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The map label for this gene is phoP [H]

Identifier: 222526878

GI number: 222526878

Start: 4553798

End: 4554502

Strand: Direct

Name: phoP [H]

Synonym: Chy400_3655

Alternate gene names: 222526878

Gene position: 4553798-4554502 (Clockwise)

Preceding gene: 222526877

Following gene: 222526879

Centisome position: 86.43

GC content: 55.32

Gene sequence:

>705_bases
ATGGAAGCAGCTACAATTCTCGTTGTTGATGACGAGCAACCAATTGTTGATCTGGTCAGCAGTTACCTGACAAACGAGGG
TTTTGTTGTGCATCGGGCTTACGATGGCCCTGGCGCGTTGGCGCTGGCGCGGAGTGTGAAGCCCGATCTGGTTGTTCTTG
ATGTGATGCTGCCGGGGCTGGACGGGATTGAGGTTTGTCGGCAGTTGCACCGCGACACCTCGGTGTTTGTACTGATGCTG
ACGGCACGCGCCGATGAGATTGATAAGCTGATCGGTTTGTCGGTCGGTGCTGATGATTATCTGACCAAGCCATTCAGTCC
GCGTGAGTTGGTCGCACGGGTGAAGGCTATTCTCCGCCGTAATCGGGTTATTCGTGCGATAGAGGTGAACCAGCGCCCGA
TTTTGCAATTTGAAGGGCTGTTGATCGACCCCGAACGGCGCGAAGTTGAACGCAACGGGGTGCGGGTTGATTTGACCCCG
CGTGAATTTGATCTGCTCTATGCACTGGCCAGCTATCCGGGGCGCGTGTTCACCCGTGAAGAGTTGCTTCAGCGTGTGTG
GGGGCCAGATTTTGCCGGTATTGATCGGGTGGTTGACGTGCATATCGGTACTCTGCGGCGCAAGCTCGATGATGATCATC
ACGGCACGCCTCTGGTGCAGACGGTTCGTGGCGTTGGTTATAAGTTTGTTGGTAGTACGCGATGA

Upstream 100 bases:

>100_bases
ACCTGTCGTTAACGGTCACGAGTATCACGGATAGAAAACGCCGTATATCCCCGTATAACAGCGTCCATTGCATCCATTGA
AGGAAGCAAGGAGTGCTGCA

Downstream 100 bases:

>100_bases
TGAAGTGGCTGCGGCAGCTCCGCTGGAAGCTATTCATTTCCCATCTGATTATCGTCTTGATGGCCTACGTCGTACTGCTG
GCCGCTGCCAATGTACTGGC

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MEAATILVVDDEQPIVDLVSSYLTNEGFVVHRAYDGPGALALARSVKPDLVVLDVMLPGLDGIEVCRQLHRDTSVFVLML
TARADEIDKLIGLSVGADDYLTKPFSPRELVARVKAILRRNRVIRAIEVNQRPILQFEGLLIDPERREVERNGVRVDLTP
REFDLLYALASYPGRVFTREELLQRVWGPDFAGIDRVVDVHIGTLRRKLDDDHHGTPLVQTVRGVGYKFVGSTR

Sequences:

>Translated_234_residues
MEAATILVVDDEQPIVDLVSSYLTNEGFVVHRAYDGPGALALARSVKPDLVVLDVMLPGLDGIEVCRQLHRDTSVFVLML
TARADEIDKLIGLSVGADDYLTKPFSPRELVARVKAILRRNRVIRAIEVNQRPILQFEGLLIDPERREVERNGVRVDLTP
REFDLLYALASYPGRVFTREELLQRVWGPDFAGIDRVVDVHIGTLRRKLDDDHHGTPLVQTVRGVGYKFVGSTR
>Mature_234_residues
MEAATILVVDDEQPIVDLVSSYLTNEGFVVHRAYDGPGALALARSVKPDLVVLDVMLPGLDGIEVCRQLHRDTSVFVLML
TARADEIDKLIGLSVGADDYLTKPFSPRELVARVKAILRRNRVIRAIEVNQRPILQFEGLLIDPERREVERNGVRVDLTP
REFDLLYALASYPGRVFTREELLQRVWGPDFAGIDRVVDVHIGTLRRKLDDDHHGTPLVQTVRGVGYKFVGSTR

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=235, Percent_Identity=44.2553191489362, Blast_Score=177, Evalue=7e-46,
Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=41.0714285714286, Blast_Score=171, Evalue=4e-44,
Organism=Escherichia coli, GI2367329, Length=230, Percent_Identity=43.9130434782609, Blast_Score=167, Evalue=6e-43,
Organism=Escherichia coli, GI1790860, Length=232, Percent_Identity=39.6551724137931, Blast_Score=154, Evalue=5e-39,
Organism=Escherichia coli, GI1789809, Length=231, Percent_Identity=36.7965367965368, Blast_Score=153, Evalue=1e-38,
Organism=Escherichia coli, GI1786911, Length=226, Percent_Identity=38.0530973451327, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI87082012, Length=226, Percent_Identity=37.6106194690265, Blast_Score=144, Evalue=5e-36,
Organism=Escherichia coli, GI1790863, Length=234, Percent_Identity=32.4786324786325, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=38.1165919282511, Blast_Score=137, Evalue=6e-34,
Organism=Escherichia coli, GI1787229, Length=228, Percent_Identity=36.8421052631579, Blast_Score=133, Evalue=9e-33,
Organism=Escherichia coli, GI145693140, Length=232, Percent_Identity=33.6206896551724, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1789402, Length=225, Percent_Identity=33.7777777777778, Blast_Score=112, Evalue=2e-26,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=34.4978165938865, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1787375, Length=225, Percent_Identity=32.4444444444444, Blast_Score=100, Evalue=6e-23,
Organism=Escherichia coli, GI1788550, Length=106, Percent_Identity=35.8490566037736, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26291; Mature: 26291

Theoretical pI: Translated: 6.05; Mature: 6.05

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEAATILVVDDEQPIVDLVSSYLTNEGFVVHRAYDGPGALALARSVKPDLVVLDVMLPGL
CCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCCCEEEEEEHHCCC
DGIEVCRQLHRDTSVFVLMLTARADEIDKLIGLSVGADDYLTKPFSPRELVARVKAILRR
CHHHHHHHHHCCCEEEEEEEECCHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHHHHHH
NRVIRAIEVNQRPILQFEGLLIDPERREVERNGVRVDLTPREFDLLYALASYPGRVFTRE
CCEEEEEECCCCCCEEECCEEECCHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCEECHH
ELLQRVWGPDFAGIDRVVDVHIGTLRRKLDDDHHGTPLVQTVRGVGYKFVGSTR
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEECCCCC
>Mature Secondary Structure
MEAATILVVDDEQPIVDLVSSYLTNEGFVVHRAYDGPGALALARSVKPDLVVLDVMLPGL
CCCEEEEEECCCCCHHHHHHHHHCCCCEEEEEECCCCCHHHHHHCCCCCEEEEEEHHCCC
DGIEVCRQLHRDTSVFVLMLTARADEIDKLIGLSVGADDYLTKPFSPRELVARVKAILRR
CHHHHHHHHHCCCEEEEEEEECCHHHHHHHHCCCCCCCHHHCCCCCHHHHHHHHHHHHHH
NRVIRAIEVNQRPILQFEGLLIDPERREVERNGVRVDLTPREFDLLYALASYPGRVFTRE
CCEEEEEECCCCCCEEECCEEECCHHHHHHHCCEEEEECCCHHHHHHHHHHCCCCEECHH
ELLQRVWGPDFAGIDRVVDVHIGTLRRKLDDDHHGTPLVQTVRGVGYKFVGSTR
HHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]