The gene/protein map for NC_012032 is currently unavailable.
Definition Chloroflexus sp. Y-400-fl chromosome, complete genome.
Accession NC_012032
Length 5,268,950

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The map label for this gene is fabG [H]

Identifier: 222526667

GI number: 222526667

Start: 4286227

End: 4286937

Strand: Reverse

Name: fabG [H]

Synonym: Chy400_3436

Alternate gene names: 222526667

Gene position: 4286937-4286227 (Counterclockwise)

Preceding gene: 222526671

Following gene: 222526666

Centisome position: 81.36

GC content: 60.34

Gene sequence:

>711_bases
ATGACGTTAAACGGCATACATGCTCTGGTGACCGGTGGTGGTCGTGGTCTCGGTCGGGCCAGTGCGCTGGCGCTGGCCCG
TGCCGGTGCCCAGGTTTCGGTATTAGCCCGCAGTGCCGACGAGGTTGCCGAAACGGTCTGGCTCATTGAAGAAAGCGGCC
AGAGCGGTTTGGGGCTGACGGCTGATGTGCGTGACCGTGCTCAACTGAACCAGGCCGTGGCTCAGGCTTACGACCACTTT
GGCCCCATCCGCGTACTGGTTGCGGCTGCTGGTGTTGGCCTGCGTGCCCCGATTCAGGAGACCAGCGAAGAGCAGTGGGA
TGCAGTGATCGATACGCTTCTCAAAGGAGTGTTCCTGAGCGCTCGTGCAGTCATTCCCCAGATGATTGAAGCTGGTGGTG
GCAACATTATCGTCATTGGCGCACCGCTTGAACGCATCGCTGTACCCGGTTTTGCCGCTTACTATGCGGCCAAAGCCGGC
GTCGATGGCCTGGCCCGGGTGATGGCCAAAGACCTTCGTCGCTTCGGGATTAATGTCAATATCGTGCATCCCGGTGGCTT
CGCCGATACGCATATGGTACGTACAACAGTACCAGAGGTGCGCACCGGTCTGCTTAGCCCCGACGAGATCGGGCCGGCGG
TGGTTGAACTGGCTGCACTGCCTCCTCGAAGCCAGACCGGGCAGACGATTGATGCCCACGCCCGAAAATGA

Upstream 100 bases:

>100_bases
GTCATAACAACCATCATTGCGTCCCTCGCTGCGGCAAAGTGTGGTATAACGATGGTGTAGTGCAAAATATTTGCAAAACA
TTGACAAAAGGAGAAGGGTT

Downstream 100 bases:

>100_bases
GTGCAAAATTAATCCGTACATGATCTTGACAAAACCTGTGCAAAGATCGAAAATATACTCATCCAAAATCTTTGAGGAGG
CGTATATCCAGATAGCGAAT

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 236; Mature: 235

Protein sequence:

>236_residues
MTLNGIHALVTGGGRGLGRASALALARAGAQVSVLARSADEVAETVWLIEESGQSGLGLTADVRDRAQLNQAVAQAYDHF
GPIRVLVAAAGVGLRAPIQETSEEQWDAVIDTLLKGVFLSARAVIPQMIEAGGGNIIVIGAPLERIAVPGFAAYYAAKAG
VDGLARVMAKDLRRFGINVNIVHPGGFADTHMVRTTVPEVRTGLLSPDEIGPAVVELAALPPRSQTGQTIDAHARK

Sequences:

>Translated_236_residues
MTLNGIHALVTGGGRGLGRASALALARAGAQVSVLARSADEVAETVWLIEESGQSGLGLTADVRDRAQLNQAVAQAYDHF
GPIRVLVAAAGVGLRAPIQETSEEQWDAVIDTLLKGVFLSARAVIPQMIEAGGGNIIVIGAPLERIAVPGFAAYYAAKAG
VDGLARVMAKDLRRFGINVNIVHPGGFADTHMVRTTVPEVRTGLLSPDEIGPAVVELAALPPRSQTGQTIDAHARK
>Mature_235_residues
TLNGIHALVTGGGRGLGRASALALARAGAQVSVLARSADEVAETVWLIEESGQSGLGLTADVRDRAQLNQAVAQAYDHFG
PIRVLVAAAGVGLRAPIQETSEEQWDAVIDTLLKGVFLSARAVIPQMIEAGGGNIIVIGAPLERIAVPGFAAYYAAKAGV
DGLARVMAKDLRRFGINVNIVHPGGFADTHMVRTTVPEVRTGLLSPDEIGPAVVELAALPPRSQTGQTIDAHARK

Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI4503817, Length=231, Percent_Identity=25.974025974026, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI40254992, Length=190, Percent_Identity=31.0526315789474, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI32483357, Length=179, Percent_Identity=32.9608938547486, Blast_Score=85, Evalue=4e-17,
Organism=Homo sapiens, GI4504505, Length=226, Percent_Identity=32.7433628318584, Blast_Score=84, Evalue=8e-17,
Organism=Homo sapiens, GI19923817, Length=250, Percent_Identity=28, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI15277342, Length=201, Percent_Identity=34.8258706467662, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI126723191, Length=177, Percent_Identity=31.638418079096, Blast_Score=78, Evalue=6e-15,
Organism=Homo sapiens, GI40254986, Length=180, Percent_Identity=28.8888888888889, Blast_Score=73, Evalue=2e-13,
Organism=Homo sapiens, GI31542939, Length=233, Percent_Identity=28.3261802575107, Blast_Score=72, Evalue=3e-13,
Organism=Homo sapiens, GI5031737, Length=179, Percent_Identity=32.4022346368715, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI33667109, Length=179, Percent_Identity=32.4022346368715, Blast_Score=71, Evalue=8e-13,
Organism=Homo sapiens, GI126723750, Length=182, Percent_Identity=30.7692307692308, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI20149619, Length=183, Percent_Identity=24.5901639344262, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI7705925, Length=220, Percent_Identity=27.7272727272727, Blast_Score=66, Evalue=2e-11,
Organism=Homo sapiens, GI209862901, Length=194, Percent_Identity=29.3814432989691, Blast_Score=65, Evalue=6e-11,
Organism=Homo sapiens, GI19923983, Length=194, Percent_Identity=29.3814432989691, Blast_Score=65, Evalue=6e-11,
Organism=Escherichia coli, GI1787335, Length=240, Percent_Identity=34.5833333333333, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1789208, Length=250, Percent_Identity=36.4, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1790717, Length=199, Percent_Identity=30.6532663316583, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI2367175, Length=242, Percent_Identity=30.9917355371901, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI87082100, Length=223, Percent_Identity=32.2869955156951, Blast_Score=88, Evalue=4e-19,
Organism=Escherichia coli, GI87082160, Length=206, Percent_Identity=28.6407766990291, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787526, Length=238, Percent_Identity=28.5714285714286, Blast_Score=78, Evalue=4e-16,
Organism=Escherichia coli, GI1788459, Length=235, Percent_Identity=29.7872340425532, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1787820, Length=223, Percent_Identity=29.5964125560538, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1789378, Length=186, Percent_Identity=31.1827956989247, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789057, Length=214, Percent_Identity=30.8411214953271, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1786812, Length=195, Percent_Identity=29.2307692307692, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI2367365, Length=184, Percent_Identity=29.3478260869565, Blast_Score=64, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=187, Percent_Identity=32.620320855615, Blast_Score=83, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI17560676, Length=236, Percent_Identity=27.1186440677966, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=188, Percent_Identity=31.9148936170213, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17562910, Length=246, Percent_Identity=29.6747967479675, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17564282, Length=203, Percent_Identity=24.6305418719212, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI25147288, Length=240, Percent_Identity=29.1666666666667, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17562906, Length=192, Percent_Identity=30.7291666666667, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17568967, Length=225, Percent_Identity=27.1111111111111, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17561402, Length=241, Percent_Identity=29.045643153527, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI71982365, Length=185, Percent_Identity=28.6486486486486, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17544670, Length=204, Percent_Identity=26.4705882352941, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17555706, Length=237, Percent_Identity=30.379746835443, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17562908, Length=191, Percent_Identity=28.7958115183246, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17560150, Length=208, Percent_Identity=27.4038461538462, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17538486, Length=188, Percent_Identity=32.4468085106383, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=211, Percent_Identity=29.3838862559242, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17567345, Length=240, Percent_Identity=22.9166666666667, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=192, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI193203117, Length=229, Percent_Identity=23.5807860262009, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71994600, Length=188, Percent_Identity=25.531914893617, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI71994604, Length=194, Percent_Identity=27.319587628866, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI193203115, Length=221, Percent_Identity=23.9819004524887, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI193204405, Length=194, Percent_Identity=29.8969072164948, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17531453, Length=226, Percent_Identity=28.7610619469027, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17565030, Length=191, Percent_Identity=32.9842931937173, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI17536651, Length=186, Percent_Identity=27.4193548387097, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17538480, Length=213, Percent_Identity=30.5164319248826, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17536025, Length=186, Percent_Identity=26.8817204301075, Blast_Score=64, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=190, Percent_Identity=28.9473684210526, Blast_Score=64, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17558628, Length=189, Percent_Identity=27.5132275132275, Blast_Score=64, Evalue=9e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=217, Percent_Identity=30.8755760368664, Blast_Score=85, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324126, Length=196, Percent_Identity=27.0408163265306, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24639444, Length=235, Percent_Identity=32.7659574468085, Blast_Score=89, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357041, Length=178, Percent_Identity=30.8988764044944, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21356301, Length=228, Percent_Identity=25.4385964912281, Blast_Score=86, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24644339, Length=186, Percent_Identity=29.0322580645161, Blast_Score=85, Evalue=4e-17,
Organism=Drosophila melanogaster, GI28571526, Length=178, Percent_Identity=30.8988764044944, Blast_Score=84, Evalue=6e-17,
Organism=Drosophila melanogaster, GI18859837, Length=224, Percent_Identity=30.3571428571429, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI21355631, Length=196, Percent_Identity=27.0408163265306, Blast_Score=77, Evalue=9e-15,
Organism=Drosophila melanogaster, GI21357673, Length=238, Percent_Identity=27.3109243697479, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI23397609, Length=207, Percent_Identity=31.4009661835749, Blast_Score=75, Evalue=4e-14,
Organism=Drosophila melanogaster, GI281364892, Length=232, Percent_Identity=27.1551724137931, Blast_Score=69, Evalue=2e-12,
Organism=Drosophila melanogaster, GI24640492, Length=172, Percent_Identity=25.5813953488372, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI21355319, Length=187, Percent_Identity=27.807486631016, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24581726, Length=180, Percent_Identity=26.1111111111111, Blast_Score=65, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24643142, Length=176, Percent_Identity=30.6818181818182, Blast_Score=65, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 24534; Mature: 24403

Theoretical pI: Translated: 6.69; Mature: 6.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure: 

>Translated Secondary Structure
MTLNGIHALVTGGGRGLGRASALALARAGAQVSVLARSADEVAETVWLIEESGQSGLGLT
CCCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ADVRDRAQLNQAVAQAYDHFGPIRVLVAAAGVGLRAPIQETSEEQWDAVIDTLLKGVFLS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHH
ARAVIPQMIEAGGGNIIVIGAPLERIAVPGFAAYYAAKAGVDGLARVMAKDLRRFGINVN
HHHHHHHHHHCCCCCEEEECCCHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCEEE
IVHPGGFADTHMVRTTVPEVRTGLLSPDEIGPAVVELAALPPRSQTGQTIDAHARK
EECCCCCCCHHHHHHHHHHHHHCCCCCHHHCHHHHHHHCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
TLNGIHALVTGGGRGLGRASALALARAGAQVSVLARSADEVAETVWLIEESGQSGLGLT
CCCCEEEEEECCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
ADVRDRAQLNQAVAQAYDHFGPIRVLVAAAGVGLRAPIQETSEEQWDAVIDTLLKGVFLS
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCCHHHCCHHHHHHHHHHHHHHHHHH
ARAVIPQMIEAGGGNIIVIGAPLERIAVPGFAAYYAAKAGVDGLARVMAKDLRRFGINVN
HHHHHHHHHHCCCCCEEEECCCHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHCCEEE
IVHPGGFADTHMVRTTVPEVRTGLLSPDEIGPAVVELAALPPRSQTGQTIDAHARK
EECCCCCCCHHHHHHHHHHHHHCCCCCHHHCHHHHHHHCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8759840; 9384377; 9534248; 8654983 [H]