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The map label for this gene is nadA [H]

Identifier: 222524794

GI number: 222524794

Start: 1939005

End: 1939976

Strand: Direct

Name: nadA [H]

Synonym: Chy400_1521

Alternate gene names: 222524794

Gene position: 1939005-1939976 (Clockwise)

Preceding gene: 222524791

Following gene: 222524795

Centisome position: 36.8

GC content: 56.17

Gene sequence:

>972_bases
ATGGTCGCCCAGATCTACGAAACAACCGGTGAAACGGCTGCCAGCCTCATCGCCGAAATTGCTGACCTCCGGCGCCAACG
CAATGCGATCATCCTGGCACATAATTACGAATACGGCGAAATTCAGGAGATTGCCGATTATGTCGGCGACTCGCTGGGTA
TGGCGCAGGCCGCAGCCCGGACCGACGCTGACGTCATTATGGTGTGCGGTGTCTACTTTATGGCCGAGACTGCCGCCATC
CTTAATCCGCAGCGGACGGTACTCATTCCCGATGCAAACGCCGGCTGCTCGCTGGCCGACTCGATTACCGTAGAGCAGTT
ACGAGCGTGGAAAGCTGCGAATCCAGGTGCGGTTGTTGTAAGTTATGTAAATACCAGTGCTGCTGTCAAGGCAGAAAGTG
ATTATTGCTGCACGTCGGGCAATGCCGAGCGAGTTATTAACGCCATCCCCGCCGATAAAACCATCTTGTTTTTGCCTGAT
ATGTTTCTCGGCAGTTATCTACGCCACAAAACAGGGCGACCGCTCAAGATTTGGGCCGGCGAGTGTCACGTCCATGCCGC
CATCCGGCCAACCATGATCGAACAGAAGCGAGCGGCAATGCCTGACGCCGAGTTTCTGATTCACCCTGAATGTGGCTGTG
TGAGTAGCGCAATGGATTATGTGGCTCGCGGCGCCATTGAGAGTCGGGGCACGCATATTCTCTCCACCGAGGGCATGATT
GCGCATGTCAACCGCTCACCGGCCAGCCGTTTTGTGGTTGCCACCGAGATTGGCGTGCTCCACCGGATGCGCAAAGCCAA
TCCGGATAAGCAGTTTGTTCCCATCGATGAGTCGATAAGCTGTCGCTACATGAAGCTGATCACGCTGGCAAAGGTGCGCG
ACAGTCTACGCGACCTGCGCGAACAGGTGACAGTACCGCCGGAGATTGCCGAACGGGCCAGAATCGCCATTGACCGAATG
CTGGCGTTGTAG

Upstream 100 bases:

>100_bases
AACATTTTTGTTAGTGACCTCTTGACAATATCTCGTCGGAGGTGTATACTCATCGCAATTGTTAAAAGTGTAATAATAAC
ACTAAATCGGAGAATATCTC

Downstream 100 bases:

>100_bases
GTCTGCGCAATCTTTGCACATTTGAAGTATTCACCTCACACCTGGCAGAGGAGCATATGATGGAAGCCCTTCCTACTCAA
CGCAGCATTCTGCAGCGCAT

Product: quinolinate synthetase complex subunit A

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 323; Mature: 323

Protein sequence:

>323_residues
MVAQIYETTGETAASLIAEIADLRRQRNAIILAHNYEYGEIQEIADYVGDSLGMAQAAARTDADVIMVCGVYFMAETAAI
LNPQRTVLIPDANAGCSLADSITVEQLRAWKAANPGAVVVSYVNTSAAVKAESDYCCTSGNAERVINAIPADKTILFLPD
MFLGSYLRHKTGRPLKIWAGECHVHAAIRPTMIEQKRAAMPDAEFLIHPECGCVSSAMDYVARGAIESRGTHILSTEGMI
AHVNRSPASRFVVATEIGVLHRMRKANPDKQFVPIDESISCRYMKLITLAKVRDSLRDLREQVTVPPEIAERARIAIDRM
LAL

Sequences:

>Translated_323_residues
MVAQIYETTGETAASLIAEIADLRRQRNAIILAHNYEYGEIQEIADYVGDSLGMAQAAARTDADVIMVCGVYFMAETAAI
LNPQRTVLIPDANAGCSLADSITVEQLRAWKAANPGAVVVSYVNTSAAVKAESDYCCTSGNAERVINAIPADKTILFLPD
MFLGSYLRHKTGRPLKIWAGECHVHAAIRPTMIEQKRAAMPDAEFLIHPECGCVSSAMDYVARGAIESRGTHILSTEGMI
AHVNRSPASRFVVATEIGVLHRMRKANPDKQFVPIDESISCRYMKLITLAKVRDSLRDLREQVTVPPEIAERARIAIDRM
LAL
>Mature_323_residues
MVAQIYETTGETAASLIAEIADLRRQRNAIILAHNYEYGEIQEIADYVGDSLGMAQAAARTDADVIMVCGVYFMAETAAI
LNPQRTVLIPDANAGCSLADSITVEQLRAWKAANPGAVVVSYVNTSAAVKAESDYCCTSGNAERVINAIPADKTILFLPD
MFLGSYLRHKTGRPLKIWAGECHVHAAIRPTMIEQKRAAMPDAEFLIHPECGCVSSAMDYVARGAIESRGTHILSTEGMI
AHVNRSPASRFVVATEIGVLHRMRKANPDKQFVPIDESISCRYMKLITLAKVRDSLRDLREQVTVPPEIAERARIAIDRM
LAL

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=319, Percent_Identity=34.4827586206897, Blast_Score=172, Evalue=2e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 35331; Mature: 35331

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVAQIYETTGETAASLIAEIADLRRQRNAIILAHNYEYGEIQEIADYVGDSLGMAQAAAR
CCCEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHC
TDADVIMVCGVYFMAETAAILNPQRTVLIPDANAGCSLADSITVEQLRAWKAANPGAVVV
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEE
SYVNTSAAVKAESDYCCTSGNAERVINAIPADKTILFLPDMFLGSYLRHKTGRPLKIWAG
EEECCCEEEEECCCCEECCCCHHHHHHCCCCCCEEEEECCHHHHHHHHHCCCCCEEEEEC
ECHVHAAIRPTMIEQKRAAMPDAEFLIHPECGCVSSAMDYVARGAIESRGTHILSTEGMI
CEEEEEECCCHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHCCHHHCCCEEEECCCEE
AHVNRSPASRFVVATEIGVLHRMRKANPDKQFVPIDESISCRYMKLITLAKVRDSLRDLR
EEECCCCCHHEEEEHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHH
EQVTVPPEIAERARIAIDRMLAL
HHCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVAQIYETTGETAASLIAEIADLRRQRNAIILAHNYEYGEIQEIADYVGDSLGMAQAAAR
CCCEEECCCCHHHHHHHHHHHHHHHHCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHC
TDADVIMVCGVYFMAETAAILNPQRTVLIPDANAGCSLADSITVEQLRAWKAANPGAVVV
CCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEE
SYVNTSAAVKAESDYCCTSGNAERVINAIPADKTILFLPDMFLGSYLRHKTGRPLKIWAG
EEECCCEEEEECCCCEECCCCHHHHHHCCCCCCEEEEECCHHHHHHHHHCCCCCEEEEEC
ECHVHAAIRPTMIEQKRAAMPDAEFLIHPECGCVSSAMDYVARGAIESRGTHILSTEGMI
CEEEEEECCCHHHHHHHHCCCCCCEEECCCCCHHHHHHHHHHHCCHHHCCCEEEECCCEE
AHVNRSPASRFVVATEIGVLHRMRKANPDKQFVPIDESISCRYMKLITLAKVRDSLRDLR
EEECCCCCHHEEEEHHHHHHHHHHHCCCCCCEECCCCCCCHHHHHHHHHHHHHHHHHHHH
EQVTVPPEIAERARIAIDRMLAL
HHCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA