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The map label for this gene is nadB1 [H]

Identifier: 222524795

GI number: 222524795

Start: 1940036

End: 1941685

Strand: Direct

Name: nadB1 [H]

Synonym: Chy400_1522

Alternate gene names: 222524795

Gene position: 1940036-1941685 (Clockwise)

Preceding gene: 222524794

Following gene: 222524800

Centisome position: 36.82

GC content: 62.55

Gene sequence:

>1650_bases
ATGGAAGCCCTTCCTACTCAACGCAGCATTCTGCAGCGCATGCCATCGGTACGCGACCGTTTTGTTGATGTCCTGGTCAT
TGGCGCCGGCGCAGCCGGTCTCACTGCAGCGCTGGCCGCGGCTGCCCGCGGTGCGCGCGTGCTCGTTCTGGCACGCGGTT
CACTCCCCGAAAGTAACTCGGCCTGGGCCCAGGGCGGGATTGCTGCCGCGTTGGACCCGGCCGACTCGCCTGGCATTCAC
GTTGCCGACACGCTTACTGCCGGAGCCGGCTTGTGTGATCCGGCAGCCGTGGCAGTGCTTGCCCACGAAGCACCGGCACT
GATGCGTGAGCTGGCGATGTTGGGGGTACCTTTCGAGCGCGATGCCGATCAATTTGCGTTAGGGCTGGAAGGAGGGCATT
CCCGGCGGCGCATTGTTCACGTCGGCGACGCAACCGGGCGGGCTGTAACCCAGGTGTTGATCGAGCGAGTGCGTGCCACG
CCACTCATCAGTGTGCGCGAGCAGGCCCAGGCGGTCGAATTGTTAACTGCCGATGAGCGCGTGGTCGGAGCGCTGGTACG
CCAGGCTGATGGGTCGTGGTGGCGAGTGTTGGCGGCGGCAACCGTGCTGGCCAGTGGCGGCGCTGGTGCGTTGTACGGGC
TAACCAGTAATCAACCAACGGCACTCGGTGAAGGCATTGCGCTGGCCTACCGCGCCGGAGCCGAGATTGCCGATATGGAG
TTTGTGCAATTTCATCCTACGGTCTATCGCACCCGCGCCGGTTATGGCTTTCTGATCACCGAAGCTGCCCGTGGTGAGGG
TGGATTGCTCTACACGCCAACCGGTCGGCGCTTTATGCCGGCCTACGATCCGCGTGCCGAACTGGCACCCCGCGATGTGG
TAACGCGCGGCATTGTTGCAGCAATGCAGGAGGAAGGCTGCGATCACGTCTTGCTCGATTTGACCCATCTGCCACCTGAT
CAGATCGAGCATCATTTTCCGACCATTTGTGCCCGTTTACGGGCCGACGGTATTGATCCGGTGCGAGATCCGATTCCGGT
GGCACCGGCAGCCCACTACCTCATGGGAGGGGTACGTACCGATTTGAGTGGCGCAACCAATCTGCCGGGACTCTTCGCTG
CCGGTGAGGTCGCCTGTACGGGTGTGCATGGCGCGAATCGGCTGGCCAGCAACTCGTTACTCGAATGCCTTGTCTTTGGT
CGCCGGGCCGGTGAAGCCGCCGCTACCTATCGCGGGCAAGCCGTTCCTATGCCTGATCCGCTTCCGATAGCACCAATTAC
CACGCCACTTCCTGCCGATTGGCGCTCTACACTGGCCGAAATCATGCGAGCCGCCGGGCCATTGCGAGACGGATCAACCC
TTCGAAGCGCACTGGCAAGGCTGGCAGAGTGGCCAATCAGTGCCGGGCCAGACGAAGCCGATCACATCACTGCTGTTAAT
GCCGGACTGACGGCACGGCTGATCGTCACTGCGGCCTTGTTGCGTACTGAGAGCCGTGGTGGCCACTTCCGGCAGGATTA
CCCGCAATCAGAGGAAGCCTGGCGCAAACATACCATCCTGCGACGTGACGCCGAACCCGCGTTTGTGCCGACGATTGCAC
CGCCGACGGCGGTTAGCCACGAGCGACAGGGGACGCATGTCTTGATCTGA

Upstream 100 bases:

>100_bases
AACGGGCCAGAATCGCCATTGACCGAATGCTGGCGTTGTAGGTCTGCGCAATCTTTGCACATTTGAAGTATTCACCTCAC
ACCTGGCAGAGGAGCATATG

Downstream 100 bases:

>100_bases
TCAGGAGTTACGCAGTTGAGAGCTGGGTAGAGCGTGGATGAGCCAGGTAGGCTCGTATCGCCTCACGGACGATGGCGGCT
GTGGCCTCAAACCACGACGT

Product: L-aspartate oxidase

Products: NA

Alternate protein names: LASPO 1; Quinolinate synthase B 1 [H]

Number of amino acids: Translated: 549; Mature: 549

Protein sequence:

>549_residues
MEALPTQRSILQRMPSVRDRFVDVLVIGAGAAGLTAALAAAARGARVLVLARGSLPESNSAWAQGGIAAALDPADSPGIH
VADTLTAGAGLCDPAAVAVLAHEAPALMRELAMLGVPFERDADQFALGLEGGHSRRRIVHVGDATGRAVTQVLIERVRAT
PLISVREQAQAVELLTADERVVGALVRQADGSWWRVLAAATVLASGGAGALYGLTSNQPTALGEGIALAYRAGAEIADME
FVQFHPTVYRTRAGYGFLITEAARGEGGLLYTPTGRRFMPAYDPRAELAPRDVVTRGIVAAMQEEGCDHVLLDLTHLPPD
QIEHHFPTICARLRADGIDPVRDPIPVAPAAHYLMGGVRTDLSGATNLPGLFAAGEVACTGVHGANRLASNSLLECLVFG
RRAGEAAATYRGQAVPMPDPLPIAPITTPLPADWRSTLAEIMRAAGPLRDGSTLRSALARLAEWPISAGPDEADHITAVN
AGLTARLIVTAALLRTESRGGHFRQDYPQSEEAWRKHTILRRDAEPAFVPTIAPPTAVSHERQGTHVLI

Sequences:

>Translated_549_residues
MEALPTQRSILQRMPSVRDRFVDVLVIGAGAAGLTAALAAAARGARVLVLARGSLPESNSAWAQGGIAAALDPADSPGIH
VADTLTAGAGLCDPAAVAVLAHEAPALMRELAMLGVPFERDADQFALGLEGGHSRRRIVHVGDATGRAVTQVLIERVRAT
PLISVREQAQAVELLTADERVVGALVRQADGSWWRVLAAATVLASGGAGALYGLTSNQPTALGEGIALAYRAGAEIADME
FVQFHPTVYRTRAGYGFLITEAARGEGGLLYTPTGRRFMPAYDPRAELAPRDVVTRGIVAAMQEEGCDHVLLDLTHLPPD
QIEHHFPTICARLRADGIDPVRDPIPVAPAAHYLMGGVRTDLSGATNLPGLFAAGEVACTGVHGANRLASNSLLECLVFG
RRAGEAAATYRGQAVPMPDPLPIAPITTPLPADWRSTLAEIMRAAGPLRDGSTLRSALARLAEWPISAGPDEADHITAVN
AGLTARLIVTAALLRTESRGGHFRQDYPQSEEAWRKHTILRRDAEPAFVPTIAPPTAVSHERQGTHVLI
>Mature_549_residues
MEALPTQRSILQRMPSVRDRFVDVLVIGAGAAGLTAALAAAARGARVLVLARGSLPESNSAWAQGGIAAALDPADSPGIH
VADTLTAGAGLCDPAAVAVLAHEAPALMRELAMLGVPFERDADQFALGLEGGHSRRRIVHVGDATGRAVTQVLIERVRAT
PLISVREQAQAVELLTADERVVGALVRQADGSWWRVLAAATVLASGGAGALYGLTSNQPTALGEGIALAYRAGAEIADME
FVQFHPTVYRTRAGYGFLITEAARGEGGLLYTPTGRRFMPAYDPRAELAPRDVVTRGIVAAMQEEGCDHVLLDLTHLPPD
QIEHHFPTICARLRADGIDPVRDPIPVAPAAHYLMGGVRTDLSGATNLPGLFAAGEVACTGVHGANRLASNSLLECLVFG
RRAGEAAATYRGQAVPMPDPLPIAPITTPLPADWRSTLAEIMRAAGPLRDGSTLRSALARLAEWPISAGPDEADHITAVN
AGLTARLIVTAALLRTESRGGHFRQDYPQSEEAWRKHTILRRDAEPAFVPTIAPPTAVSHERQGTHVLI

Specific function: Catalyzes the oxidation of L-aspartate to iminoaspartate [H]

COG id: COG0029

COG function: function code H; Aspartate oxidase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAD-dependent oxidoreductase 2 family. NadB subfamily [H]

Homologues:

Organism=Homo sapiens, GI156416003, Length=535, Percent_Identity=35.1401869158879, Blast_Score=226, Evalue=3e-59,
Organism=Escherichia coli, GI1788928, Length=528, Percent_Identity=41.4772727272727, Blast_Score=359, Evalue=1e-100,
Organism=Escherichia coli, GI1790597, Length=520, Percent_Identity=31.9230769230769, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI1786942, Length=586, Percent_Identity=33.617747440273, Blast_Score=220, Evalue=2e-58,
Organism=Caenorhabditis elegans, GI17550100, Length=562, Percent_Identity=32.2064056939502, Blast_Score=219, Evalue=3e-57,
Organism=Caenorhabditis elegans, GI17505833, Length=573, Percent_Identity=31.7626527050611, Blast_Score=218, Evalue=9e-57,
Organism=Caenorhabditis elegans, GI71986328, Length=476, Percent_Identity=30.0420168067227, Blast_Score=118, Evalue=7e-27,
Organism=Saccharomyces cerevisiae, GI6322701, Length=600, Percent_Identity=34, Blast_Score=238, Evalue=1e-63,
Organism=Saccharomyces cerevisiae, GI6322416, Length=568, Percent_Identity=35.387323943662, Blast_Score=236, Evalue=5e-63,
Organism=Saccharomyces cerevisiae, GI6320788, Length=476, Percent_Identity=29.8319327731092, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6322511, Length=310, Percent_Identity=29.0322580645161, Blast_Score=82, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17137288, Length=588, Percent_Identity=34.3537414965986, Blast_Score=229, Evalue=5e-60,
Organism=Drosophila melanogaster, GI24655642, Length=588, Percent_Identity=34.3537414965986, Blast_Score=229, Evalue=5e-60,
Organism=Drosophila melanogaster, GI24655647, Length=588, Percent_Identity=34.3537414965986, Blast_Score=229, Evalue=5e-60,
Organism=Drosophila melanogaster, GI24663005, Length=583, Percent_Identity=32.4185248713551, Blast_Score=219, Evalue=4e-57,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003953
- InterPro:   IPR013027
- InterPro:   IPR015939
- InterPro:   IPR004112
- InterPro:   IPR005288 [H]

Pfam domain/function: PF00890 FAD_binding_2; PF02910 Succ_DH_flav_C [H]

EC number: =1.4.3.16 [H]

Molecular weight: Translated: 57898; Mature: 57898

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEALPTQRSILQRMPSVRDRFVDVLVIGAGAAGLTAALAAAARGARVLVLARGSLPESNS
CCCCCHHHHHHHHCHHHHHHHEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCC
AWAQGGIAAALDPADSPGIHVADTLTAGAGLCDPAAVAVLAHEAPALMRELAMLGVPFER
CHHCCCEEEEECCCCCCCEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
DADQFALGLEGGHSRRRIVHVGDATGRAVTQVLIERVRATPLISVREQAQAVELLTADER
CCCCEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VVGALVRQADGSWWRVLAAATVLASGGAGALYGLTSNQPTALGEGIALAYRAGAEIADME
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHCCCEEEEECCCCCHHCCC
FVQFHPTVYRTRAGYGFLITEAARGEGGLLYTPTGRRFMPAYDPRAELAPRDVVTRGIVA
EEEECCHHEEECCCCEEEEEECCCCCCCEEECCCCCEECCCCCCCCCCCCHHHHHHHHHH
AMQEEGCDHVLLDLTHLPPDQIEHHFPTICARLRADGIDPVRDPIPVAPAAHYLMGGVRT
HHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCHHH
DLSGATNLPGLFAAGEVACTGVHGANRLASNSLLECLVFGRRAGEAAATYRGQAVPMPDP
CCCCCCCCCCCEECCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCC
LPIAPITTPLPADWRSTLAEIMRAAGPLRDGSTLRSALARLAEWPISAGPDEADHITAVN
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEC
AGLTARLIVTAALLRTESRGGHFRQDYPQSEEAWRKHTILRRDAEPAFVPTIAPPTAVSH
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
ERQGTHVLI
CCCCCEECC
>Mature Secondary Structure
MEALPTQRSILQRMPSVRDRFVDVLVIGAGAAGLTAALAAAARGARVLVLARGSLPESNS
CCCCCHHHHHHHHCHHHHHHHEEEEEECCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCC
AWAQGGIAAALDPADSPGIHVADTLTAGAGLCDPAAVAVLAHEAPALMRELAMLGVPFER
CHHCCCEEEEECCCCCCCEEEEHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
DADQFALGLEGGHSRRRIVHVGDATGRAVTQVLIERVRATPLISVREQAQAVELLTADER
CCCCEEEECCCCCCCCEEEEECCCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VVGALVRQADGSWWRVLAAATVLASGGAGALYGLTSNQPTALGEGIALAYRAGAEIADME
HHHHHHHHCCCCHHHHHHHHHHHHCCCCCEEEEECCCCCCHHCCCEEEEECCCCCHHCCC
FVQFHPTVYRTRAGYGFLITEAARGEGGLLYTPTGRRFMPAYDPRAELAPRDVVTRGIVA
EEEECCHHEEECCCCEEEEEECCCCCCCEEECCCCCEECCCCCCCCCCCCHHHHHHHHHH
AMQEEGCDHVLLDLTHLPPDQIEHHFPTICARLRADGIDPVRDPIPVAPAAHYLMGGVRT
HHHHCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCHHH
DLSGATNLPGLFAAGEVACTGVHGANRLASNSLLECLVFGRRAGEAAATYRGQAVPMPDP
CCCCCCCCCCCEECCCEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHCCCCCCCCCCC
LPIAPITTPLPADWRSTLAEIMRAAGPLRDGSTLRSALARLAEWPISAGPDEADHITAVN
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCEEEEC
AGLTARLIVTAALLRTESRGGHFRQDYPQSEEAWRKHTILRRDAEPAFVPTIAPPTAVSH
CCCHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCCCC
ERQGTHVLI
CCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11823852 [H]