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The map label for this gene is atoS [C]

Identifier: 222523547

GI number: 222523547

Start: 299744

End: 301672

Strand: Reverse

Name: atoS [C]

Synonym: Chy400_0253

Alternate gene names: 222523547

Gene position: 301672-299744 (Counterclockwise)

Preceding gene: 222523548

Following gene: 222523545

Centisome position: 5.73

GC content: 53.81

Gene sequence:

>1929_bases
ATGCCCGATGACACAATCTTGCTCTTACTGGCCAATGCGGCAAATCGGGAATTGCTTCGTGACTGGTTGGGGCACCATTA
TCAAACAATTATTGCTGATAGTGAGGCCGATCTCCAGCGCTCCTTTCAGCTTTGTATCGTCGATGGCCCCGCGTTGGCGA
CGTTTGAAGCGGCCATTCAGGCCCGGCGTGCTGCGGCATATCCCATCTTTCTCCCCTTCTTGCTGGTCACGACGCGAGGT
GATGTTAAGTATCATACGCATCACCTCTGGCAGACGGTTGATGAGCTGGTGATCAGTCCGATCCAGAAGGTCGAATTGCA
GGCGCGGATAGAGATTCTTTTACGTGCCCGCCGTCTGGCCCTGGAAGTGAGTCGCTTGCAGCAGGCCATGCTTTCCAGTA
CCCAAACCTGGTTGCAGTTGGCAGTGCAATCGGCCCAGATTGGGTTGTGGGAGTGGGATTTGCAGACCAATCGGGTCTTC
TTTTCGCCGGAGTGGAAGGCGCAAATTGGCTATGCTGCCGATGAGCTTGTTGATTCCCTCACCGTGTGGGAGGAGCTGAT
CCATCCCGATGATCGCGAACGTTGTCTGAACCTGTTGTACCGTTATCTGCATCGGCCCTGGCCCGATTTTGCCCTTGAGT
TTCGCCTTCGTCATAAGAATGGGAGCTACCGCTGGATTCGTTCGCAGGCGGCGCTGATTTACGATCAGCACGGTCGCCCG
ACGCATATGCTGGGTGCCCATTTTGATTTGACCGAACGGAAGCAAATGGAAGAAGAGCAGCAACAACTTGCTGAGCAGCT
CTTTCAGTCGCAGAAGTTAGAGGCGATTGGGGCGCTGACCAGTGGTATTGCCCACGACCTGAATAATCTGTTGGTGCCGA
TCATCGGGTTCGCTGAGATGGGGATGCTTGAAGTAACGCCTGATAATCCGTTGTACAGCGATTTTGATCAGATTCGGGCG
GCTGGGATTCGGGCTACCGCATTGACCCGGCGGATTTTAACGTTTAGCCGTCAGCAACGAATGGAGATGAAGCCAATCCA
CATTAGTCGGGTTATCAGCGATTTTGTGGCGATTCTCCGTCGGATTATCGGGGAACGAATTGATATTCAGCTTCAGCTTG
CGTCAGATCTGCCACCGGTACAGGCGGATGTCAGTCAGATTGAACAGATACTGCTGAATCTGGTGATCAATGCCCGTGAT
GCTATCGAAGGTAATGGCACGATTACCATCACTACCGCGTTTGTGAGTCCTGAAGACACTGACTTCCCCTGGCCTGCTGA
TGTGCCCCCCGGTGATTACATCGCTTTGCAGATTAGTGATACCGGCTGTGGGATTGATTCGGCGATCCGTTCACGGATAT
TTGAACCATTCTTTACCACAAAGCCGTCCGGTAAAGGTACCGGGCTTGGCCTGGCGACGGTTGCGGCGATTGTGAAGCAG
CATCACGGTTACATCGATGTGCAGAGTTTGCCCGGTCAGGGTGCAACGTTTACCGTGTACCTGCCGGCACTGAAGGATGG
AGCGGCGGTTAGCGAAGATGTTGCGTTCAGTAAAGATCAGCTCTTTGGTCACGAGACGGTGCTGGTGGTTGAAGATGAAC
CGGCAGTACTGCACCTGATTGCCAGTGCGCTACGTCTGCATGGCTATCAGGTGATAGAGGCGACAGATGCGCAGTATGGG
TTGGGGTTAGCTGCCAGTCACCAGGGAACTATCGATCTTCTGATTACCGACGTGATGCTGCCGACGCTTAATGGTGATGA
ACTGTATCGACAGCTTCGTGGGTTGTATCCGCAGGCACGGGTGTTGTATATCTCGGCCTATGTGGACAGCGAACACGTAG
GGCCTGACGTAACACCGATTCTGGCGAAGCCGTTCACTTTGCAACGGCTCCTGCAACAGGTACGCGCTATTCTGACGGCA
GCGGTCTGA

Upstream 100 bases:

>100_bases
TAATGATCCGCTACCCGACGATACAAAAGAATGAGTACATGCTGTCATGCGGCAACCCACAACAGAGGGCACGATATAGC
AGGCACGAAAAGGATGCACC

Downstream 100 bases:

>100_bases
TCAGGAGTGGCTCCAGTCGCCCCTGCCGCCAGACACCGATCACGTCAACGTAACCGTAGCGCACGTTGCCCCTGGCCTGT
AATTGGCTCAAAGCTGCTTG

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: Blue-light-activated histidine kinase; Response regulator [H]

Number of amino acids: Translated: 642; Mature: 641

Protein sequence:

>642_residues
MPDDTILLLLANAANRELLRDWLGHHYQTIIADSEADLQRSFQLCIVDGPALATFEAAIQARRAAAYPIFLPFLLVTTRG
DVKYHTHHLWQTVDELVISPIQKVELQARIEILLRARRLALEVSRLQQAMLSSTQTWLQLAVQSAQIGLWEWDLQTNRVF
FSPEWKAQIGYAADELVDSLTVWEELIHPDDRERCLNLLYRYLHRPWPDFALEFRLRHKNGSYRWIRSQAALIYDQHGRP
THMLGAHFDLTERKQMEEEQQQLAEQLFQSQKLEAIGALTSGIAHDLNNLLVPIIGFAEMGMLEVTPDNPLYSDFDQIRA
AGIRATALTRRILTFSRQQRMEMKPIHISRVISDFVAILRRIIGERIDIQLQLASDLPPVQADVSQIEQILLNLVINARD
AIEGNGTITITTAFVSPEDTDFPWPADVPPGDYIALQISDTGCGIDSAIRSRIFEPFFTTKPSGKGTGLGLATVAAIVKQ
HHGYIDVQSLPGQGATFTVYLPALKDGAAVSEDVAFSKDQLFGHETVLVVEDEPAVLHLIASALRLHGYQVIEATDAQYG
LGLAASHQGTIDLLITDVMLPTLNGDELYRQLRGLYPQARVLYISAYVDSEHVGPDVTPILAKPFTLQRLLQQVRAILTA
AV

Sequences:

>Translated_642_residues
MPDDTILLLLANAANRELLRDWLGHHYQTIIADSEADLQRSFQLCIVDGPALATFEAAIQARRAAAYPIFLPFLLVTTRG
DVKYHTHHLWQTVDELVISPIQKVELQARIEILLRARRLALEVSRLQQAMLSSTQTWLQLAVQSAQIGLWEWDLQTNRVF
FSPEWKAQIGYAADELVDSLTVWEELIHPDDRERCLNLLYRYLHRPWPDFALEFRLRHKNGSYRWIRSQAALIYDQHGRP
THMLGAHFDLTERKQMEEEQQQLAEQLFQSQKLEAIGALTSGIAHDLNNLLVPIIGFAEMGMLEVTPDNPLYSDFDQIRA
AGIRATALTRRILTFSRQQRMEMKPIHISRVISDFVAILRRIIGERIDIQLQLASDLPPVQADVSQIEQILLNLVINARD
AIEGNGTITITTAFVSPEDTDFPWPADVPPGDYIALQISDTGCGIDSAIRSRIFEPFFTTKPSGKGTGLGLATVAAIVKQ
HHGYIDVQSLPGQGATFTVYLPALKDGAAVSEDVAFSKDQLFGHETVLVVEDEPAVLHLIASALRLHGYQVIEATDAQYG
LGLAASHQGTIDLLITDVMLPTLNGDELYRQLRGLYPQARVLYISAYVDSEHVGPDVTPILAKPFTLQRLLQQVRAILTA
AV
>Mature_641_residues
PDDTILLLLANAANRELLRDWLGHHYQTIIADSEADLQRSFQLCIVDGPALATFEAAIQARRAAAYPIFLPFLLVTTRGD
VKYHTHHLWQTVDELVISPIQKVELQARIEILLRARRLALEVSRLQQAMLSSTQTWLQLAVQSAQIGLWEWDLQTNRVFF
SPEWKAQIGYAADELVDSLTVWEELIHPDDRERCLNLLYRYLHRPWPDFALEFRLRHKNGSYRWIRSQAALIYDQHGRPT
HMLGAHFDLTERKQMEEEQQQLAEQLFQSQKLEAIGALTSGIAHDLNNLLVPIIGFAEMGMLEVTPDNPLYSDFDQIRAA
GIRATALTRRILTFSRQQRMEMKPIHISRVISDFVAILRRIIGERIDIQLQLASDLPPVQADVSQIEQILLNLVINARDA
IEGNGTITITTAFVSPEDTDFPWPADVPPGDYIALQISDTGCGIDSAIRSRIFEPFFTTKPSGKGTGLGLATVAAIVKQH
HGYIDVQSLPGQGATFTVYLPALKDGAAVSEDVAFSKDQLFGHETVLVVEDEPAVLHLIASALRLHGYQVIEATDAQYGL
GLAASHQGTIDLLITDVMLPTLNGDELYRQLRGLYPQARVLYISAYVDSEHVGPDVTPILAKPFTLQRLLQQVRAILTAA
V

Specific function: Photosensitive kinase and response regulator that is involved in increased bacterial virulence upon exposure to light [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=387, Percent_Identity=29.7157622739018, Blast_Score=143, Evalue=3e-35,
Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=31.7073170731707, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI48994928, Length=501, Percent_Identity=23.9520958083832, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI87081816, Length=353, Percent_Identity=26.0623229461756, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788713, Length=240, Percent_Identity=30.8333333333333, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI145693157, Length=288, Percent_Identity=24.6527777777778, Blast_Score=79, Evalue=8e-16,
Organism=Escherichia coli, GI1789149, Length=293, Percent_Identity=27.9863481228669, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI1788381, Length=140, Percent_Identity=31.4285714285714, Blast_Score=63, Evalue=6e-11,
Organism=Escherichia coli, GI1786912, Length=252, Percent_Identity=26.984126984127, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 71980; Mature: 71849

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPDDTILLLLANAANRELLRDWLGHHYQTIIADSEADLQRSFQLCIVDGPALATFEAAIQ
CCCCEEEEEEECCCCHHHHHHHHCCCEEEEEECCHHHHHCCEEEEEECCCCHHHHHHHHH
ARRAAAYPIFLPFLLVTTRGDVKYHTHHLWQTVDELVISPIQKVELQARIEILLRARRLA
HHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
LEVSRLQQAMLSSTQTWLQLAVQSAQIGLWEWDLQTNRVFFSPEWKAQIGYAADELVDSL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEECCCCCCCCCCHHHHHHHHH
TVWEELIHPDDRERCLNLLYRYLHRPWPDFALEFRLRHKNGSYRWIRSQAALIYDQHGRP
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEECCEEEEEECCCCC
THMLGAHFDLTERKQMEEEQQQLAEQLFQSQKLEAIGALTSGIAHDLNNLLVPIIGFAEM
CEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GMLEVTPDNPLYSDFDQIRAAGIRATALTRRILTFSRQQRMEMKPIHISRVISDFVAILR
CEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
RIIGERIDIQLQLASDLPPVQADVSQIEQILLNLVINARDAIEGNGTITITTAFVSPEDT
HHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCC
DFPWPADVPPGDYIALQISDTGCGIDSAIRSRIFEPFFTTKPSGKGTGLGLATVAAIVKQ
CCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHHH
HHGYIDVQSLPGQGATFTVYLPALKDGAAVSEDVAFSKDQLFGHETVLVVEDEPAVLHLI
HCCEEEEECCCCCCCEEEEEECCCCCCCCCCHHHCCCHHHHCCCEEEEEECCCCHHHHHH
ASALRLHGYQVIEATDAQYGLGLAASHQGTIDLLITDVMLPTLNGDELYRQLRGLYPQAR
HHHHHHCCEEEEEECCCCCCCCEEECCCCCEEEEEEHHHHCCCCHHHHHHHHHCCCCCCE
VLYISAYVDSEHVGPDVTPILAKPFTLQRLLQQVRAILTAAV
EEEEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PDDTILLLLANAANRELLRDWLGHHYQTIIADSEADLQRSFQLCIVDGPALATFEAAIQ
CCCEEEEEEECCCCHHHHHHHHCCCEEEEEECCHHHHHCCEEEEEECCCCHHHHHHHHH
ARRAAAYPIFLPFLLVTTRGDVKYHTHHLWQTVDELVISPIQKVELQARIEILLRARRLA
HHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHH
LEVSRLQQAMLSSTQTWLQLAVQSAQIGLWEWDLQTNRVFFSPEWKAQIGYAADELVDSL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCEEEECCCCCCCCCCHHHHHHHHH
TVWEELIHPDDRERCLNLLYRYLHRPWPDFALEFRLRHKNGSYRWIRSQAALIYDQHGRP
HHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEEEEECCCCEEEEECCEEEEEECCCCC
THMLGAHFDLTERKQMEEEQQQLAEQLFQSQKLEAIGALTSGIAHDLNNLLVPIIGFAEM
CEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GMLEVTPDNPLYSDFDQIRAAGIRATALTRRILTFSRQQRMEMKPIHISRVISDFVAILR
CEEEECCCCCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
RIIGERIDIQLQLASDLPPVQADVSQIEQILLNLVINARDAIEGNGTITITTAFVSPEDT
HHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEEECCCCC
DFPWPADVPPGDYIALQISDTGCGIDSAIRSRIFEPFFTTKPSGKGTGLGLATVAAIVKQ
CCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHCCCHHCCCCCCCCCCCHHHHHHHHHHH
HHGYIDVQSLPGQGATFTVYLPALKDGAAVSEDVAFSKDQLFGHETVLVVEDEPAVLHLI
HCCEEEEECCCCCCCEEEEEECCCCCCCCCCHHHCCCHHHHCCCEEEEEECCCCHHHHHH
ASALRLHGYQVIEATDAQYGLGLAASHQGTIDLLITDVMLPTLNGDELYRQLRGLYPQAR
HHHHHHCCEEEEEECCCCCCCCEEECCCCCEEEEEEHHHHCCCCHHHHHHHHHCCCCCCE
VLYISAYVDSEHVGPDVTPILAKPFTLQRLLQQVRAILTAAV
EEEEEEEECCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA