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The map label for this gene is yghZ [H]

Identifier: 220931113

GI number: 220931113

Start: 269839

End: 270792

Strand: Direct

Name: yghZ [H]

Synonym: Hore_02650

Alternate gene names: 220931113

Gene position: 269839-270792 (Clockwise)

Preceding gene: 220931112

Following gene: 220931114

Centisome position: 10.47

GC content: 37.74

Gene sequence:

>954_bases
ATGAAATATAGAAAACTAGGGAGAGCGGGAGTAAAAGTAAGTGAACTTAGTTTAGGAAGCTGGTTAACATATGGTAATTC
TGTTGAAAAGGAAAGGGCCATTAAGACTATTGATAAAGCTTATGAGCTTGGTATTAATTCCTTTGATACTGCCAATGTTT
ATGCCAGGGGGGAAGCTGAAAAAATTGTTGGTAGGGCTTTAAATAAGTATCCCAGGGAATCTTATGTTCTGGCAACTAAG
GTTTACTGGCCTATGGGGGATGGTGTTAATGATAGGGGTTTATCGAAAAAACATGTTTTTGAACAACTACATCAGAGTTT
AAAAAGACTGAACCATGATTATGTAGATATTCTCTACTGCCACCGTTTTGATGAGGAGACTCCCCTGTATGAAACACTAC
GGACTATTGATGATCTAATTCGTCAGGGTAAGGTATTATATGTAGGGGTAAGTGAATGGACTGCTTATCAGATTGTAGAG
GGATTAAGGGTACAGGACCAATACCTTTTAGATCGCCTGGTTGTAAATCAACCTATTTATAACCTTTTCAACAGGTATAT
TGAAAAAGAAATTGTACCTACCTGTATGGAAAACGGTCTGGGATTAATTGTTTTTTCTCCATTAGCCCAGGGTTTACTTA
CAGGTAAATATAGATTAGGAGAACCTATTCCTGAAAATAGTAGGGCCGCAGACCCTAAGGCAAATAGATGGATTAAAGAA
ATCCTGACCGAAGAAAACCTTTCTAAAGTGGAAAAATTAATTGAGATTGCCAATGAACTGGGGATAAGTATGCCACAATT
AGCCCTGGCCTGGATTTTACATCAACCGGGAATTACTAGTGCTTTAATTGGTGCCAGTAAACCAGAACAGGTAGAAGAGA
ATGTAAAGGCAGTAGATGTATCTCTTTCTGAAGATGTATTAGAAAGGATAGAAAAAATAATGCAGGGTGAGTAA

Upstream 100 bases:

>100_bases
AAAAAGCAGGACTAAAACTATAAAGTGTTTTTGATGTTTATTATTCATATATTTAAAGGGATTGGAAATTCAATAAACAT
AAAGGAGTGTGGATTATTAA

Downstream 100 bases:

>100_bases
TTGTTTTTTAAAATATCCATATACTTTTTAATAATTTGCGGGAAGTGTTAAAGAAATAACGGGTAGTTAGTTTAGAAAAA
TAACAATAAGGGGGTATCTA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 317; Mature: 317

Protein sequence:

>317_residues
MKYRKLGRAGVKVSELSLGSWLTYGNSVEKERAIKTIDKAYELGINSFDTANVYARGEAEKIVGRALNKYPRESYVLATK
VYWPMGDGVNDRGLSKKHVFEQLHQSLKRLNHDYVDILYCHRFDEETPLYETLRTIDDLIRQGKVLYVGVSEWTAYQIVE
GLRVQDQYLLDRLVVNQPIYNLFNRYIEKEIVPTCMENGLGLIVFSPLAQGLLTGKYRLGEPIPENSRAADPKANRWIKE
ILTEENLSKVEKLIEIANELGISMPQLALAWILHQPGITSALIGASKPEQVEENVKAVDVSLSEDVLERIEKIMQGE

Sequences:

>Translated_317_residues
MKYRKLGRAGVKVSELSLGSWLTYGNSVEKERAIKTIDKAYELGINSFDTANVYARGEAEKIVGRALNKYPRESYVLATK
VYWPMGDGVNDRGLSKKHVFEQLHQSLKRLNHDYVDILYCHRFDEETPLYETLRTIDDLIRQGKVLYVGVSEWTAYQIVE
GLRVQDQYLLDRLVVNQPIYNLFNRYIEKEIVPTCMENGLGLIVFSPLAQGLLTGKYRLGEPIPENSRAADPKANRWIKE
ILTEENLSKVEKLIEIANELGISMPQLALAWILHQPGITSALIGASKPEQVEENVKAVDVSLSEDVLERIEKIMQGE
>Mature_317_residues
MKYRKLGRAGVKVSELSLGSWLTYGNSVEKERAIKTIDKAYELGINSFDTANVYARGEAEKIVGRALNKYPRESYVLATK
VYWPMGDGVNDRGLSKKHVFEQLHQSLKRLNHDYVDILYCHRFDEETPLYETLRTIDDLIRQGKVLYVGVSEWTAYQIVE
GLRVQDQYLLDRLVVNQPIYNLFNRYIEKEIVPTCMENGLGLIVFSPLAQGLLTGKYRLGEPIPENSRAADPKANRWIKE
ILTEENLSKVEKLIEIANELGISMPQLALAWILHQPGITSALIGASKPEQVEENVKAVDVSLSEDVLERIEKIMQGE

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI27436964, Length=324, Percent_Identity=41.358024691358, Blast_Score=240, Evalue=1e-63,
Organism=Homo sapiens, GI27436962, Length=324, Percent_Identity=41.0493827160494, Blast_Score=238, Evalue=6e-63,
Organism=Homo sapiens, GI27436966, Length=324, Percent_Identity=40.7407407407407, Blast_Score=236, Evalue=2e-62,
Organism=Homo sapiens, GI27436969, Length=323, Percent_Identity=40.2476780185758, Blast_Score=233, Evalue=2e-61,
Organism=Homo sapiens, GI4504825, Length=321, Percent_Identity=40.1869158878505, Blast_Score=231, Evalue=5e-61,
Organism=Homo sapiens, GI27436971, Length=307, Percent_Identity=39.413680781759, Blast_Score=215, Evalue=3e-56,
Organism=Homo sapiens, GI223718702, Length=284, Percent_Identity=31.3380281690141, Blast_Score=102, Evalue=3e-22,
Organism=Homo sapiens, GI41152114, Length=284, Percent_Identity=31.3380281690141, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI41327764, Length=277, Percent_Identity=31.0469314079422, Blast_Score=99, Evalue=4e-21,
Organism=Escherichia coli, GI1789375, Length=329, Percent_Identity=40.7294832826748, Blast_Score=220, Evalue=8e-59,
Organism=Escherichia coli, GI87081735, Length=320, Percent_Identity=37.8125, Blast_Score=206, Evalue=1e-54,
Organism=Escherichia coli, GI1788070, Length=326, Percent_Identity=35.5828220858896, Blast_Score=162, Evalue=4e-41,
Organism=Escherichia coli, GI1789199, Length=346, Percent_Identity=32.3699421965318, Blast_Score=152, Evalue=2e-38,
Organism=Escherichia coli, GI1788081, Length=306, Percent_Identity=28.4313725490196, Blast_Score=105, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI212645785, Length=325, Percent_Identity=27.3846153846154, Blast_Score=91, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6325169, Length=340, Percent_Identity=29.1176470588235, Blast_Score=162, Evalue=5e-41,
Organism=Saccharomyces cerevisiae, GI6323998, Length=321, Percent_Identity=28.3489096573209, Blast_Score=120, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6319958, Length=299, Percent_Identity=28.4280936454849, Blast_Score=114, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6319951, Length=339, Percent_Identity=27.4336283185841, Blast_Score=105, Evalue=9e-24,
Organism=Saccharomyces cerevisiae, GI6322615, Length=251, Percent_Identity=24.3027888446215, Blast_Score=87, Evalue=2e-18,
Organism=Saccharomyces cerevisiae, GI6321052, Length=150, Percent_Identity=32, Blast_Score=71, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24640980, Length=337, Percent_Identity=29.3768545994065, Blast_Score=152, Evalue=4e-37,
Organism=Drosophila melanogaster, GI45549126, Length=336, Percent_Identity=29.4642857142857, Blast_Score=150, Evalue=8e-37,
Organism=Drosophila melanogaster, GI24646155, Length=310, Percent_Identity=30.6451612903226, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24646159, Length=310, Percent_Identity=25.8064516129032, Blast_Score=98, Evalue=9e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR005399
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: NA

Molecular weight: Translated: 36071; Mature: 36071

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKYRKLGRAGVKVSELSLGSWLTYGNSVEKERAIKTIDKAYELGINSFDTANVYARGEAE
CCCHHHHCCCCEEEHCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHH
KIVGRALNKYPRESYVLATKVYWPMGDGVNDRGLSKKHVFEQLHQSLKRLNHDYVDILYC
HHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
HRFDEETPLYETLRTIDDLIRQGKVLYVGVSEWTAYQIVEGLRVQDQYLLDRLVVNQPIY
HHCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCHHH
NLFNRYIEKEIVPTCMENGLGLIVFSPLAQGLLTGKYRLGEPIPENSRAADPKANRWIKE
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCHHCCCCCCCCCCCCCCHHHHHHHH
ILTEENLSKVEKLIEIANELGISMPQLALAWILHQPGITSALIGASKPEQVEENVKAVDV
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHCC
SLSEDVLERIEKIMQGE
CHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKYRKLGRAGVKVSELSLGSWLTYGNSVEKERAIKTIDKAYELGINSFDTANVYARGEAE
CCCHHHHCCCCEEEHCCCCHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCCCEEECCHHH
KIVGRALNKYPRESYVLATKVYWPMGDGVNDRGLSKKHVFEQLHQSLKRLNHDYVDILYC
HHHHHHHHHCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHH
HRFDEETPLYETLRTIDDLIRQGKVLYVGVSEWTAYQIVEGLRVQDQYLLDRLVVNQPIY
HHCCCCCHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCHHHHHHHHHHHHCCHHH
NLFNRYIEKEIVPTCMENGLGLIVFSPLAQGLLTGKYRLGEPIPENSRAADPKANRWIKE
HHHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHCCCHHCCCCCCCCCCCCCCHHHHHHHH
ILTEENLSKVEKLIEIANELGISMPQLALAWILHQPGITSALIGASKPEQVEENVKAVDV
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHCCCCHHHHHHHHHHHCC
SLSEDVLERIEKIMQGE
CHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]