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The map label for this gene is prcA

Identifier: 221230165

GI number: 221230165

Start: 1576576

End: 1577373

Strand: Direct

Name: prcA

Synonym: MLBr_01323

Alternate gene names: 221230165

Gene position: 1576576-1577373 (Clockwise)

Preceding gene: 221230164

Following gene: 221230166

Centisome position: 48.24

GC content: 57.52

Gene sequence:

>798_bases
ATGAGTTTTCCGTACTTCATCTCACCTGAACAGGCTATGCGCGAGCGCAGCGAGCTCGCTCGCAAGGGTATTGCTCGGGG
CCGCAGCGTGGTAGCGCTAGCCTATGCTGGCGGTGTTTTGTTCGTCGCGGAGAACCCGTCACGCTCACTGCAGAAGATCA
GTGAACTCTACGATCGAGTGGGCTTTGCGGCCGCAGGTAAGTTTAATGAGTTCGACAATTTACGCCGCGGCGGGATCCAA
TTCGCTGATACTCGAGGTTACGCTTACGATCGCCGCGACGTCACCGGCCGGCAGTTGGCCAACGTCTATGCGCAGACGCT
TGGCACTATCTTCACGGAACAGGCCAAACCTTACGAGGTTGAGTTGTGCGTAGCTGAGGTCGCGCACTACGGTGAAACGA
AACCGCCTGAGCTGTACCGGATCACCTACGACGGATCGATCAACGATGAACCGCATTTTATGGTCATGGGTGGCACTACG
GAGTCGATCGCTAACGCGCTCAAAGAGTCGTATGCCGAGAATGCCAGCTTGACCGACGCTCTGGGGATCGCGGTCGCAGC
ACTGCGGGCGGGCAGTGCGGATGCCGCCGGTAGCGATCAACCTACCCTTGGCGTGGCCAGCTTAGAGGTGGCTGTCCTCG
ATGCTAATCGGCCGCGGCGGGCTTTTCGTCGGATCATCGGCTCTGGGTTGGAAGCATTGCTGCGGGAAAAGGATTCCAAA
GGCTCCAAGGGTGCTCAGAATCCCAAAGGTGCTAGGGATTCGAAGAATTCGAAATCCTACGGCGAATCAACGGATTAG

Upstream 100 bases:

>100_bases
CGGCCGAGGTAACAGAAAGCCGGATCGCCGAACTTGCCCGCGAGATTATCGAAAGCCGTTCACGTGCGTACACTCTTGGC
TCCTTTGGCGGGAGTGAGAA

Downstream 100 bases:

>100_bases
GGGTACAGCCTATTCGGTCGTTAGTGGCCAATTCGGCGAGCACTTGCAGCACTCATTGCTGTTAGACTGCATACGACGGT
GACGTTGGACGACCACGTCA

Product: proteasome alpha-type subunit 1

Products: NA

Alternate protein names: 20S proteasome alpha subunit; Proteasome core protein PrcA

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MSFPYFISPEQAMRERSELARKGIARGRSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQ
FADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSINDEPHFMVMGGTT
ESIANALKESYAENASLTDALGIAVAALRAGSADAAGSDQPTLGVASLEVAVLDANRPRRAFRRIIGSGLEALLREKDSK
GSKGAQNPKGARDSKNSKSYGESTD

Sequences:

>Translated_265_residues
MSFPYFISPEQAMRERSELARKGIARGRSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQ
FADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSINDEPHFMVMGGTT
ESIANALKESYAENASLTDALGIAVAALRAGSADAAGSDQPTLGVASLEVAVLDANRPRRAFRRIIGSGLEALLREKDSK
GSKGAQNPKGARDSKNSKSYGESTD
>Mature_264_residues
SFPYFISPEQAMRERSELARKGIARGRSVVALAYAGGVLFVAENPSRSLQKISELYDRVGFAAAGKFNEFDNLRRGGIQF
ADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHYGETKPPELYRITYDGSINDEPHFMVMGGTTE
SIANALKESYAENASLTDALGIAVAALRAGSADAAGSDQPTLGVASLEVAVLDANRPRRAFRRIIGSGLEALLREKDSKG
SKGAQNPKGARDSKNSKSYGESTD

Specific function: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation

COG id: COG0638

COG function: function code O; 20S proteasome, alpha and beta subunits

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1A family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PSA_MYCLB (B8ZRF4)

Other databases:

- EMBL:   FM211192
- RefSeq:   YP_002503581.1
- ProteinModelPortal:   B8ZRF4
- SMR:   B8ZRF4
- EnsemblBacteria:   EBMYCT00000087443
- GeneID:   7325004
- GenomeReviews:   FM211192_GR
- GeneTree:   EBGT00050000016603
- HOGENOM:   HBG292323
- OMA:   AVGKYNE
- ProtClustDB:   CLSK872007
- GO:   GO:0005737
- HAMAP:   MF_00289_B
- InterPro:   IPR022296
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03691

Pfam domain/function: PF00227 Proteasome

EC number: =3.4.25.1

Molecular weight: Translated: 28677; Mature: 28546

Theoretical pI: Translated: 7.49; Mature: 7.49

Prosite motif: PS00388 PROTEASOME_A_1; PS51475 PROTEASOME_A_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPYFISPEQAMRERSELARKGIARGRSVVALAYAGGVLFVAENPSRSLQKISELYDRV
CCCCCEECHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEECCCHHHHHHHHHHHHHH
GFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEV
CHHHCCCCHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEH
ELCVAEVAHYGETKPPELYRITYDGSINDEPHFMVMGGTTESIANALKESYAENASLTDA
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCHHHH
LGIAVAALRAGSADAAGSDQPTLGVASLEVAVLDANRPRRAFRRIIGSGLEALLREKDSK
HHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
GSKGAQNPKGARDSKNSKSYGESTD
CCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SFPYFISPEQAMRERSELARKGIARGRSVVALAYAGGVLFVAENPSRSLQKISELYDRV
CCCCEECHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEECCCHHHHHHHHHHHHHH
GFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTIFTEQAKPYEV
CHHHCCCCHHHHHHHHCCCEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCEEH
ELCVAEVAHYGETKPPELYRITYDGSINDEPHFMVMGGTTESIANALKESYAENASLTDA
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCCHHHH
LGIAVAALRAGSADAAGSDQPTLGVASLEVAVLDANRPRRAFRRIIGSGLEALLREKDSK
HHHHHHHHHCCCCCCCCCCCCCEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
GSKGAQNPKGARDSKNSKSYGESTD
CCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA