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The map label for this gene is ileS

Identifier: 221230085

GI number: 221230085

Start: 1410813

End: 1413992

Strand: Direct

Name: ileS

Synonym: MLBr_01195

Alternate gene names: 221230085

Gene position: 1410813-1413992 (Clockwise)

Preceding gene: 221230084

Following gene: 221230087

Centisome position: 43.17

GC content: 57.36

Gene sequence:

>3180_bases
ATGACTAACAGCGCCTACCCGCGCACTGATCTGGGCGCCGACCAGCGCGGCGGGTCCCCAAATTTTCCTGCGCTGGAAGC
CCAGGTCCTCGATTATTGGTCCAACGACGATACTTTTCGGGCCAGCATTGCCCGTTGTGACGACGCCCCCGAGTACGTGT
TCTATGACGGACCTCCCTTCGCTAATGGCCTGCCACATTATGGGCATCTGCTCACCGGCTATGTGAAGGACATCGTTCCG
CGTTACCGCACCATGTGTGGCTATAAAGTAGAGCGCCGCTTTGGTTGGGACACGCACGGGCTGCCTGCTGAACTCGAAGT
CGAGCGGCAGCTGGGTATCACCGACAAATCCCAGATCGACGCCATGGGAATTGCCGCGTTCAACGAAGCATGTCGCAAAT
CGGTGTTGCGCTACACGGAAGAATGGCAGGCGTATGTAACCCGCCAGGCACGCTGGGTCGACTTCGATAACGATTACAAG
ACACTCGATCTGTCTTACATGGAGTCTGTGATCTGGGCGTTTAAACAGCTGTGGGACAAGGGTTTGGCTTACGAGAGCTA
TCGGGTGTTGCCGTACTGCTGGCGCGACGAAACCCCGCTATCCAACCACGAACTGCGGATGGACGACGACGTCTATCAAA
GCCGCCAGGATCCGGCGGTCACGCTGGGCTTCAAGGTGCTGGGGGGTGACGATGAGGACCTAGTTGGTGCTTATCTTTTG
GTGTGGACGACGACGCCCTGGACTTTACCGTCGAACCTGGCCGTTGCCGTCCATCCGGATGTAACCTATGTCGATGTCAG
GGCAGGCGATCGCCGTTTCGTTTTGGCACAGGCGCGTCTGACCGCCTATGCTCGAGAGCTAGGCGACGAACCTGAGGTGC
TTGCCACCTATCGTGGCGCCGATCTGCTGGGCAGGCACTATCTGCCGCCGTTCCAGTATTTCTACGAGTCTGCTAGAAAT
GCATTTCAGGTGCTCCCAGGAGACTTCGTGACTACTGATGACGGCACTGGTATCGTCCATATCGCGCCTGCCTACGGCGA
AGATGATATGGCGACCGCCGATAAGGTTGGCATCGTTCCGGTCACGCCGGTTGACTCTAACGGTTGTTTTGACGCCACCG
TGCCCGATTACCAGGGGCAACACGTCTTTGAGGCCAACGCCCAGATCATCCGCGATCTGAAGAACCAGAGTGGCTCGGCG
GCGGTGAACGGCGCGGTGTTGCTTCGTCACGAAACCTATGAGCACCCATACCCGCATTGCTGGCGATGTCGCAATCCGCT
GATCTACCGTGCGGTGTCGTCATGGTTTGTCGCTGTGACGGAATTCCGGGACCGCATGGTGGAACTGAACCAACAGATCA
CCTGGTATCCTGAGCACGTCAAGGACGGTCAGTTTGGTAAGTGGTTGCAGGGTGCCCGCGATTGGTCTATCTCACGAAAC
CGCTACTGGGGCACCCCAATCCCAGTGTGGAAATCGGATGATCCCGATTACCCAAGAATCGATGTATACGGCAGCTTGGA
TGAGCTGGAGCGCGATTTCGGGGTGCGTCCCACGAATCTACATCGCCCCTACATCGACGAGCTCACCCGACCCAACCCTG
ACGATCCCACCGGCCTTAGCACCATGCGACGGATCCCGGATGTTTTTGATGTGTGGTTCGACTCGGGTTCTATGCCATAT
GCTCAGGTGCACTACCCGTTTGAAAACGATGACTGGTTCGACGGGTTCGATTCCGCTGATTCTGACAAGCAGGTCGACGC
GCACTATCCTGGCGATTTCATCGTCGAGTACATCGGTCAGGCCCGCGGTTGGTTCTACACGCTACATGTGCTGGCCACTG
CACTCTTTGATCGTCCGGCATTCAAAACCTGTATAGCGCATGGGGTTGTGCTGGGGTCTAACGGTCAGAAGATGAGCAAG
TCGTTGCGCAACTACCCAGACGTTACTGAGATATTTGACCGCGACGGTTCCGATGCCATGCGGTGGTTTTTGATGGCCTC
GCCGATCCTGCGTGGCGGCAACCTCATCATAACTGAACCCGGAATCCGCGAAGGCATGCGGCAGGTGCTGCTGCCGTTGT
GGAACGCTTACAGTTTTTTGGCCCTTTACGCACCCAAAATCGGTACCTGGCATACGGATGTGTCGCATGTGTTGGACCGT
TATATTCTGGCGAAGCTGGCGGTACTGCGTGATGATCTCAGTCAGGCGATGGAGGTCTGTGATATCTCTGGGGCCTGCGA
ACAGCTTCGCCAATTCACCGAGCCGCTAACGAATTGGTATTTGCGACGGTCGCGTGCGCGGTTCTGGGACGAAGATGTTG
ATGCTATCGATACCCTGCACACCGTGCTGGAAGTGACCGCCAGGTTGGCTGCACCACTTCTCCCGTTGATCACCGAGATT
ATTTGGCGCAGTGTCACTGGTGGGCGTTCGGTACACCTGACCGATTGGCCGCAAGCCAACCAGCTACCCGCCGACCCTGA
CCTGGTTGCTGTGATGGATCAGGTCCGACAAGTGTGTTCCGCAGCGTCATCGCTGCGCAAGGCTAAGAAGCTTCGGGTAC
GCCTTCCTCTACCGAAACTCGTTGTAGCAGTGTATAATTCACAGAGACTAAAGCCCTACATTGACTTAATCGGCGATGAG
CTTAACGTCAAGCAGATAGAACTGACCGATGCTATTGACACCTACGGCCGATTTGAGTTCACCGTCAACGCTCGAGTGGC
CGGGCCGCGATTGGGAAGGGATGTGCAGGCTGCCATCAAGGTGGTAAAGGCGGGAGAAGGGGTCGCCAACCCGGATGGCA
CCCTGACCGCCGGGCCCGTTGTGCTGCAACCTGACGAGTACAGTTCGCGGTTGGTGGCCGCTAACCCGGAATTTACCGCG
GAGCTGCCCGACGGGTCCGGTCTTGTTGTGTTGGACGATACGGTGACTCCCGAACTGGAGGCCGAGGGCTGGGCCAAGGA
TCGGATCCGCGAACTACAGGAGTTGCGTAAGTTGATCGGGCTGGATGTTTCCGATCGTATCCGGGTGTTGATGTCGGTGC
CGGCCGAGCGGGCTGACTGGGCGCGCGTCCATCGCGACTTCATCGCTAGGGAAATCCTGGCCACCAGCTTCGAGTTTGGC
GAGCCGGCTGATTCGGTGGCTATCGGAGATGGCGTCCGAGTCAGCCTTTTAAAGGTCTAA

Upstream 100 bases:

>100_bases
CGTGCGTTCGCGTGCGGCAAGCGGGGTGGTACCGCGGCGCTCGCGCACCTAGCGCGTCGTCGTCCCCGTGTCTACTTGTG
TTAAGTGGCCCAGGAGACGT

Downstream 100 bases:

>100_bases
GTCGAGATCAACGTTTTGCCGAGCAAGTTTGAGAACAGCCTTGCAAAACGTCGATCTCGACGCGAGAAAATCAGATGTAA
TCGCGTGCCAGCGCTGCGTG

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 1059; Mature: 1058

Protein sequence:

>1059_residues
MTNSAYPRTDLGADQRGGSPNFPALEAQVLDYWSNDDTFRASIARCDDAPEYVFYDGPPFANGLPHYGHLLTGYVKDIVP
RYRTMCGYKVERRFGWDTHGLPAELEVERQLGITDKSQIDAMGIAAFNEACRKSVLRYTEEWQAYVTRQARWVDFDNDYK
TLDLSYMESVIWAFKQLWDKGLAYESYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPAVTLGFKVLGGDDEDLVGAYLL
VWTTTPWTLPSNLAVAVHPDVTYVDVRAGDRRFVLAQARLTAYARELGDEPEVLATYRGADLLGRHYLPPFQYFYESARN
AFQVLPGDFVTTDDGTGIVHIAPAYGEDDMATADKVGIVPVTPVDSNGCFDATVPDYQGQHVFEANAQIIRDLKNQSGSA
AVNGAVLLRHETYEHPYPHCWRCRNPLIYRAVSSWFVAVTEFRDRMVELNQQITWYPEHVKDGQFGKWLQGARDWSISRN
RYWGTPIPVWKSDDPDYPRIDVYGSLDELERDFGVRPTNLHRPYIDELTRPNPDDPTGLSTMRRIPDVFDVWFDSGSMPY
AQVHYPFENDDWFDGFDSADSDKQVDAHYPGDFIVEYIGQARGWFYTLHVLATALFDRPAFKTCIAHGVVLGSNGQKMSK
SLRNYPDVTEIFDRDGSDAMRWFLMASPILRGGNLIITEPGIREGMRQVLLPLWNAYSFLALYAPKIGTWHTDVSHVLDR
YILAKLAVLRDDLSQAMEVCDISGACEQLRQFTEPLTNWYLRRSRARFWDEDVDAIDTLHTVLEVTARLAAPLLPLITEI
IWRSVTGGRSVHLTDWPQANQLPADPDLVAVMDQVRQVCSAASSLRKAKKLRVRLPLPKLVVAVYNSQRLKPYIDLIGDE
LNVKQIELTDAIDTYGRFEFTVNARVAGPRLGRDVQAAIKVVKAGEGVANPDGTLTAGPVVLQPDEYSSRLVAANPEFTA
ELPDGSGLVVLDDTVTPELEAEGWAKDRIRELQELRKLIGLDVSDRIRVLMSVPAERADWARVHRDFIAREILATSFEFG
EPADSVAIGDGVRVSLLKV

Sequences:

>Translated_1059_residues
MTNSAYPRTDLGADQRGGSPNFPALEAQVLDYWSNDDTFRASIARCDDAPEYVFYDGPPFANGLPHYGHLLTGYVKDIVP
RYRTMCGYKVERRFGWDTHGLPAELEVERQLGITDKSQIDAMGIAAFNEACRKSVLRYTEEWQAYVTRQARWVDFDNDYK
TLDLSYMESVIWAFKQLWDKGLAYESYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPAVTLGFKVLGGDDEDLVGAYLL
VWTTTPWTLPSNLAVAVHPDVTYVDVRAGDRRFVLAQARLTAYARELGDEPEVLATYRGADLLGRHYLPPFQYFYESARN
AFQVLPGDFVTTDDGTGIVHIAPAYGEDDMATADKVGIVPVTPVDSNGCFDATVPDYQGQHVFEANAQIIRDLKNQSGSA
AVNGAVLLRHETYEHPYPHCWRCRNPLIYRAVSSWFVAVTEFRDRMVELNQQITWYPEHVKDGQFGKWLQGARDWSISRN
RYWGTPIPVWKSDDPDYPRIDVYGSLDELERDFGVRPTNLHRPYIDELTRPNPDDPTGLSTMRRIPDVFDVWFDSGSMPY
AQVHYPFENDDWFDGFDSADSDKQVDAHYPGDFIVEYIGQARGWFYTLHVLATALFDRPAFKTCIAHGVVLGSNGQKMSK
SLRNYPDVTEIFDRDGSDAMRWFLMASPILRGGNLIITEPGIREGMRQVLLPLWNAYSFLALYAPKIGTWHTDVSHVLDR
YILAKLAVLRDDLSQAMEVCDISGACEQLRQFTEPLTNWYLRRSRARFWDEDVDAIDTLHTVLEVTARLAAPLLPLITEI
IWRSVTGGRSVHLTDWPQANQLPADPDLVAVMDQVRQVCSAASSLRKAKKLRVRLPLPKLVVAVYNSQRLKPYIDLIGDE
LNVKQIELTDAIDTYGRFEFTVNARVAGPRLGRDVQAAIKVVKAGEGVANPDGTLTAGPVVLQPDEYSSRLVAANPEFTA
ELPDGSGLVVLDDTVTPELEAEGWAKDRIRELQELRKLIGLDVSDRIRVLMSVPAERADWARVHRDFIAREILATSFEFG
EPADSVAIGDGVRVSLLKV
>Mature_1058_residues
TNSAYPRTDLGADQRGGSPNFPALEAQVLDYWSNDDTFRASIARCDDAPEYVFYDGPPFANGLPHYGHLLTGYVKDIVPR
YRTMCGYKVERRFGWDTHGLPAELEVERQLGITDKSQIDAMGIAAFNEACRKSVLRYTEEWQAYVTRQARWVDFDNDYKT
LDLSYMESVIWAFKQLWDKGLAYESYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPAVTLGFKVLGGDDEDLVGAYLLV
WTTTPWTLPSNLAVAVHPDVTYVDVRAGDRRFVLAQARLTAYARELGDEPEVLATYRGADLLGRHYLPPFQYFYESARNA
FQVLPGDFVTTDDGTGIVHIAPAYGEDDMATADKVGIVPVTPVDSNGCFDATVPDYQGQHVFEANAQIIRDLKNQSGSAA
VNGAVLLRHETYEHPYPHCWRCRNPLIYRAVSSWFVAVTEFRDRMVELNQQITWYPEHVKDGQFGKWLQGARDWSISRNR
YWGTPIPVWKSDDPDYPRIDVYGSLDELERDFGVRPTNLHRPYIDELTRPNPDDPTGLSTMRRIPDVFDVWFDSGSMPYA
QVHYPFENDDWFDGFDSADSDKQVDAHYPGDFIVEYIGQARGWFYTLHVLATALFDRPAFKTCIAHGVVLGSNGQKMSKS
LRNYPDVTEIFDRDGSDAMRWFLMASPILRGGNLIITEPGIREGMRQVLLPLWNAYSFLALYAPKIGTWHTDVSHVLDRY
ILAKLAVLRDDLSQAMEVCDISGACEQLRQFTEPLTNWYLRRSRARFWDEDVDAIDTLHTVLEVTARLAAPLLPLITEII
WRSVTGGRSVHLTDWPQANQLPADPDLVAVMDQVRQVCSAASSLRKAKKLRVRLPLPKLVVAVYNSQRLKPYIDLIGDEL
NVKQIELTDAIDTYGRFEFTVNARVAGPRLGRDVQAAIKVVKAGEGVANPDGTLTAGPVVLQPDEYSSRLVAANPEFTAE
LPDGSGLVVLDDTVTPELEAEGWAKDRIRELQELRKLIGLDVSDRIRVLMSVPAERADWARVHRDFIAREILATSFEFGE
PADSVAIGDGVRVSLLKV

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily

Homologues:

Organism=Homo sapiens, GI94721239, Length=1090, Percent_Identity=38.9908256880734, Blast_Score=727, Evalue=0.0,
Organism=Homo sapiens, GI94721241, Length=1090, Percent_Identity=38.9908256880734, Blast_Score=727, Evalue=0.0,
Organism=Homo sapiens, GI46852147, Length=843, Percent_Identity=28.1138790035587, Blast_Score=284, Evalue=3e-76,
Organism=Homo sapiens, GI5454158, Length=936, Percent_Identity=22.542735042735, Blast_Score=138, Evalue=3e-32,
Organism=Homo sapiens, GI268370297, Length=914, Percent_Identity=22.9759299781182, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI268370295, Length=872, Percent_Identity=22.9357798165138, Blast_Score=136, Evalue=1e-31,
Organism=Homo sapiens, GI268370293, Length=914, Percent_Identity=22.9759299781182, Blast_Score=135, Evalue=2e-31,
Organism=Escherichia coli, GI2367096, Length=894, Percent_Identity=25.3914988814318, Blast_Score=278, Evalue=1e-75,
Organism=Caenorhabditis elegans, GI17541896, Length=1044, Percent_Identity=38.2183908045977, Blast_Score=670, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980946, Length=833, Percent_Identity=24.3697478991597, Blast_Score=217, Evalue=3e-56,
Organism=Caenorhabditis elegans, GI72001587, Length=811, Percent_Identity=22.8113440197287, Blast_Score=140, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1066, Percent_Identity=37.5234521575985, Blast_Score=681, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325217, Length=814, Percent_Identity=24.2014742014742, Blast_Score=212, Evalue=2e-55,
Organism=Saccharomyces cerevisiae, GI6321531, Length=896, Percent_Identity=23.1026785714286, Blast_Score=160, Evalue=9e-40,
Organism=Drosophila melanogaster, GI28574730, Length=1051, Percent_Identity=38.6298763082778, Blast_Score=683, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668547, Length=1051, Percent_Identity=38.6298763082778, Blast_Score=683, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668543, Length=1051, Percent_Identity=38.6298763082778, Blast_Score=683, Evalue=0.0,
Organism=Drosophila melanogaster, GI281366294, Length=793, Percent_Identity=25.7250945775536, Blast_Score=215, Evalue=1e-55,
Organism=Drosophila melanogaster, GI17864482, Length=883, Percent_Identity=23.4428086070215, Blast_Score=144, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24653289, Length=883, Percent_Identity=23.4428086070215, Blast_Score=144, Evalue=4e-34,
Organism=Drosophila melanogaster, GI21355675, Length=888, Percent_Identity=22.5225225225225, Blast_Score=138, Evalue=2e-32,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_MYCLE (Q9X7E5)

Other databases:

- EMBL:   AL049478
- EMBL:   AL583921
- PIR:   E87058
- RefSeq:   NP_301871.1
- ProteinModelPortal:   Q9X7E5
- SMR:   Q9X7E5
- EnsemblBacteria:   EBMYCT00000028740
- GeneID:   910297
- GenomeReviews:   AL450380_GR
- KEGG:   mle:ML1195
- NMPDR:   fig|272631.1.peg.743
- Leproma:   ML1195
- GeneTree:   EBGT00050000015649
- HOGENOM:   HBG577712
- OMA:   DCHGLPA
- ProtClustDB:   PRK06039
- BioCyc:   MLEP272631:ML1195-MONOMER
- BRENDA:   6.1.1.5
- GO:   GO:0005737
- HAMAP:   MF_02003
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 119810; Mature: 119679

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 640-640

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNSAYPRTDLGADQRGGSPNFPALEAQVLDYWSNDDTFRASIARCDDAPEYVFYDGPPF
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEECCCCC
ANGLPHYGHLLTGYVKDIVPRYRTMCGYKVERRFGWDTHGLPAELEVERQLGITDKSQID
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEHHHCCCCCHHHHH
AMGIAAFNEACRKSVLRYTEEWQAYVTRQARWVDFDNDYKTLDLSYMESVIWAFKQLWDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEHHHHHHHHHHHHHHHHH
GLAYESYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPAVTLGFKVLGGDDEDLVGAYLL
CCCCCCEEECEEEECCCCCCCCCCCCCCHHHHHCCCCCEEEEEEEEECCCCCHHHEEEEE
VWTTTPWTLPSNLAVAVHPDVTYVDVRAGDRRFVLAQARLTAYARELGDEPEVLATYRGA
EEECCCCCCCCCCEEEECCCEEEEEECCCCCEEEEHHHHHHHHHHHHCCCCCEEEEECCH
DLLGRHYLPPFQYFYESARNAFQVLPGDFVTTDDGTGIVHIAPAYGEDDMATADKVGIVP
HHHHCCCCCHHHHHHHHHHHHEEECCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCEEE
VTPVDSNGCFDATVPDYQGQHVFEANAQIIRDLKNQSGSAAVNGAVLLRHETYEHPYPHC
CCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCEEECCEEEEEECCCCCCCCCH
WRCRNPLIYRAVSSWFVAVTEFRDRMVELNQQITWYPEHVKDGQFGKWLQGARDWSISRN
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHCCCCCCHHHHCCCCCCCCCCC
RYWGTPIPVWKSDDPDYPRIDVYGSLDELERDFGVRPTNLHRPYIDELTRPNPDDPTGLS
CCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCHHH
TMRRIPDVFDVWFDSGSMPYAQVHYPFENDDWFDGFDSADSDKQVDAHYPGDFIVEYIGQ
HHHHCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
ARGWFYTLHVLATALFDRPAFKTCIAHGVVLGSNGQKMSKSLRNYPDVTEIFDRDGSDAM
HCCHHHHHHHHHHHHHCCHHHHHHHHHCEEECCCCHHHHHHHHCCCCHHHHHCCCCHHHH
RWFLMASPILRGGNLIITEPGIREGMRQVLLPLWNAYSFLALYAPKIGTWHTDVSHVLDR
HHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
YILAKLAVLRDDLSQAMEVCDISGACEQLRQFTEPLTNWYLRRSRARFWDEDVDAIDTLH
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TVLEVTARLAAPLLPLITEIIWRSVTGGRSVHLTDWPQANQLPADPDLVAVMDQVRQVCS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
AASSLRKAKKLRVRLPLPKLVVAVYNSQRLKPYIDLIGDELNVKQIELTDAIDTYGRFEF
HHHHHHHHHHHEEECCCHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEEHHHHHCCCEEEE
TVNARVAGPRLGRDVQAAIKVVKAGEGVANPDGTLTAGPVVLQPDEYSSRLVAANPEFTA
EEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEECCCEEECCCCCCCEEEECCCCEEE
ELPDGSGLVVLDDTVTPELEAEGWAKDRIRELQELRKLIGLDVSDRIRVLMSVPAERADW
ECCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHH
ARVHRDFIAREILATSFEFGEPADSVAIGDGVRVSLLKV
HHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEEEEC
>Mature Secondary Structure 
TNSAYPRTDLGADQRGGSPNFPALEAQVLDYWSNDDTFRASIARCDDAPEYVFYDGPPF
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHCCCCCCEEEECCCCC
ANGLPHYGHLLTGYVKDIVPRYRTMCGYKVERRFGWDTHGLPAELEVERQLGITDKSQID
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCEEEHHHCCCCCHHHHH
AMGIAAFNEACRKSVLRYTEEWQAYVTRQARWVDFDNDYKTLDLSYMESVIWAFKQLWDK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCEEEHHHHHHHHHHHHHHHHH
GLAYESYRVLPYCWRDETPLSNHELRMDDDVYQSRQDPAVTLGFKVLGGDDEDLVGAYLL
CCCCCCEEECEEEECCCCCCCCCCCCCCHHHHHCCCCCEEEEEEEEECCCCCHHHEEEEE
VWTTTPWTLPSNLAVAVHPDVTYVDVRAGDRRFVLAQARLTAYARELGDEPEVLATYRGA
EEECCCCCCCCCCEEEECCCEEEEEECCCCCEEEEHHHHHHHHHHHHCCCCCEEEEECCH
DLLGRHYLPPFQYFYESARNAFQVLPGDFVTTDDGTGIVHIAPAYGEDDMATADKVGIVP
HHHHCCCCCHHHHHHHHHHHHEEECCCCEEECCCCCEEEEEECCCCCCCCCCCCCCCEEE
VTPVDSNGCFDATVPDYQGQHVFEANAQIIRDLKNQSGSAAVNGAVLLRHETYEHPYPHC
CCCCCCCCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCEEECCEEEEEECCCCCCCCCH
WRCRNPLIYRAVSSWFVAVTEFRDRMVELNQQITWYPEHVKDGQFGKWLQGARDWSISRN
HHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHCCCCCCHHHHCCCCCCCCCCC
RYWGTPIPVWKSDDPDYPRIDVYGSLDELERDFGVRPTNLHRPYIDELTRPNPDDPTGLS
CCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCCCCCCCCHHHHHCCCCCCCCCHHH
TMRRIPDVFDVWFDSGSMPYAQVHYPFENDDWFDGFDSADSDKQVDAHYPGDFIVEYIGQ
HHHHCCHHHHHHHCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
ARGWFYTLHVLATALFDRPAFKTCIAHGVVLGSNGQKMSKSLRNYPDVTEIFDRDGSDAM
HCCHHHHHHHHHHHHHCCHHHHHHHHHCEEECCCCHHHHHHHHCCCCHHHHHCCCCHHHH
RWFLMASPILRGGNLIITEPGIREGMRQVLLPLWNAYSFLALYAPKIGTWHTDVSHVLDR
HHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
YILAKLAVLRDDLSQAMEVCDISGACEQLRQFTEPLTNWYLRRSRARFWDEDVDAIDTLH
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
TVLEVTARLAAPLLPLITEIIWRSVTGGRSVHLTDWPQANQLPADPDLVAVMDQVRQVCS
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHH
AASSLRKAKKLRVRLPLPKLVVAVYNSQRLKPYIDLIGDELNVKQIELTDAIDTYGRFEF
HHHHHHHHHHHEEECCCHHHHHHHHCCCCCCHHHHHCCCCCCCEEEEEHHHHHCCCEEEE
TVNARVAGPRLGRDVQAAIKVVKAGEGVANPDGTLTAGPVVLQPDEYSSRLVAANPEFTA
EEEEEECCCCCCHHHHHHHHHHHCCCCCCCCCCCEECCCEEECCCCCCCEEEECCCCEEE
ELPDGSGLVVLDDTVTPELEAEGWAKDRIRELQELRKLIGLDVSDRIRVLMSVPAERADW
ECCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHH
ARVHRDFIAREILATSFEFGEPADSVAIGDGVRVSLLKV
HHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002