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The map label for this gene is thrC [H]

Identifier: 221230038

GI number: 221230038

Start: 1321004

End: 1322086

Strand: Direct

Name: thrC [H]

Synonym: MLBr_01130

Alternate gene names: 221230038

Gene position: 1321004-1322086 (Clockwise)

Preceding gene: 221230037

Following gene: 221230039

Centisome position: 40.42

GC content: 61.22

Gene sequence:

>1083_bases
GTGAGCGGCCAGCAGACGACCACCCACCAGCCTTGGCCGGGTGTGATCGCAGCGTACCGAGACCGACTACCAGTGGGCGA
CGATTGGACCCCGGTTACCTTGCTAGAAGGTGGCACGCCGCTCATTGCTGCGCCCAGACTCTCCGAACAGACTGGCTGCA
CGATTCACCTCAAGGTAGAGGGCCTCAACCCCACCGGCTCCTTCAAAGACAGGGGCATGACGATGGCGGTGACCGATGCA
CTGGCCCGCGGGCAACGTGCCGTGTTATGCGCGTCGACGGGAAACACCTCGGCGTCGGCGGCGGCATACGCTGCCCGCGC
CGGTATTACCTGTGCGGTGCTAATTCCGCAGGGTAAAATTGCGATGGGCAAGCTCGCACAGGCGGTCATGCATGGAGCCA
AGATCATTCAGATCGACGGCAACTTCGACGATTGCCTGGAACTGGCTCGTAAAATGGCTGCTGATTTCCCGATGATCTCG
TTGGTCAACTCGGTTAACCCGGTGCGAATCGAAGGTCAAAAGACAGCGGTGTTCGAGATCGTTGACGCGCTAGGCACCGC
ACCACACGTGCATGCCCTTCCGGTCGGCAACGCTGGGAACATCACTGCGTACTGGAAAGGATACACCGAATATCACGCTG
ATGGTCTGATCGACAGACTGCCTAGGATGTTGGGTACTCAGGCCGCGGGCGCGGCTCCCCTGGTACTCGGCGAGCCTGTG
AGCCATCCCGAAACCATCGCTACTGCGATCCGCATTGGCTCGCCGGCGTCATGGACGTCGGCTGTCGAAGCCCAGCAGCA
ATCCAAGGGACGATTCCTGGCCGCGACGGATGAGGAGATTCTGGCTGCATACCATCTGGTGGCACGTGCTGAAGGCGTCT
TCGTCGAACCCGCATCGGCGGCCAGCATCGCCGGCCTCCTCAAGGCCATCGATGGTGGCTGGGTGGCTCGTGGGTCAACG
GTGGTGTGTACGATAACCGGCAACGGTCTGAAGGATCCCGACACGGCGTTGAAGGATATGCCGAGCGTCTCCCCAGTGCC
TGTCGATGCGGTCGCTGTTGTCGAGCAGTTAGGGCTGGTCTAG

Upstream 100 bases:

>100_bases
GCGCCACCGACGCCGCGCTCTCCGAAACCGTCGATGCGTTGGCTGACTTAGACGTCGTGCAGGGTGTCACAAGTGTGTTG
CGACTGGAAGGAATCAGCCT

Downstream 100 bases:

>100_bases
TGGTGATCGCAAGTGCGACGCAGTTGGGTGCGGTGGGGCGCCACTCGTTGGGCTCAGTGAAAGGCTGTTGGTGACCTGGA
TGCTGCCTGCTGGTCTGGTG

Product: threonine synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 359

Protein sequence:

>360_residues
MSGQQTTTHQPWPGVIAAYRDRLPVGDDWTPVTLLEGGTPLIAAPRLSEQTGCTIHLKVEGLNPTGSFKDRGMTMAVTDA
LARGQRAVLCASTGNTSASAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPMIS
LVNSVNPVRIEGQKTAVFEIVDALGTAPHVHALPVGNAGNITAYWKGYTEYHADGLIDRLPRMLGTQAAGAAPLVLGEPV
SHPETIATAIRIGSPASWTSAVEAQQQSKGRFLAATDEEILAAYHLVARAEGVFVEPASAASIAGLLKAIDGGWVARGST
VVCTITGNGLKDPDTALKDMPSVSPVPVDAVAVVEQLGLV

Sequences:

>Translated_360_residues
MSGQQTTTHQPWPGVIAAYRDRLPVGDDWTPVTLLEGGTPLIAAPRLSEQTGCTIHLKVEGLNPTGSFKDRGMTMAVTDA
LARGQRAVLCASTGNTSASAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPMIS
LVNSVNPVRIEGQKTAVFEIVDALGTAPHVHALPVGNAGNITAYWKGYTEYHADGLIDRLPRMLGTQAAGAAPLVLGEPV
SHPETIATAIRIGSPASWTSAVEAQQQSKGRFLAATDEEILAAYHLVARAEGVFVEPASAASIAGLLKAIDGGWVARGST
VVCTITGNGLKDPDTALKDMPSVSPVPVDAVAVVEQLGLV
>Mature_359_residues
SGQQTTTHQPWPGVIAAYRDRLPVGDDWTPVTLLEGGTPLIAAPRLSEQTGCTIHLKVEGLNPTGSFKDRGMTMAVTDAL
ARGQRAVLCASTGNTSASAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPMISL
VNSVNPVRIEGQKTAVFEIVDALGTAPHVHALPVGNAGNITAYWKGYTEYHADGLIDRLPRMLGTQAAGAAPLVLGEPVS
HPETIATAIRIGSPASWTSAVEAQQQSKGRFLAATDEEILAAYHLVARAEGVFVEPASAASIAGLLKAIDGGWVARGSTV
VCTITGNGLKDPDTALKDMPSVSPVPVDAVAVVEQLGLV

Specific function: Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine [H]

COG id: COG0498

COG function: function code E; Threonine synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the threonine synthase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001926
- InterPro:   IPR000634
- InterPro:   IPR004450 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.2.3.1 [H]

Molecular weight: Translated: 37385; Mature: 37254

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00165 DEHYDRATASE_SER_THR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSGQQTTTHQPWPGVIAAYRDRLPVGDDWTPVTLLEGGTPLIAAPRLSEQTGCTIHLKVE
CCCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCEEEEEEE
GLNPTGSFKDRGMTMAVTDALARGQRAVLCASTGNTSASAAAYAARAGITCAVLIPQGKI
CCCCCCCCCCCCCEEEEHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCC
AMGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPMISLVNSVNPVRIEGQKTAVFEI
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHCCCCEEECCCCHHHHHH
VDALGTAPHVHALPVGNAGNITAYWKGYTEYHADGLIDRLPRMLGTQAAGAAPLVLGEPV
HHHHCCCCCEEEEECCCCCCEEEEECCCHHHHHCHHHHHHHHHHCCCCCCCCCEEECCCC
SHPETIATAIRIGSPASWTSAVEAQQQSKGRFLAATDEEILAAYHLVARAEGVFVEPASA
CCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHCCCEEECCCCH
ASIAGLLKAIDGGWVARGSTVVCTITGNGLKDPDTALKDMPSVSPVPVDAVAVVEQLGLV
HHHHHHHHHHCCCEEECCCEEEEEEECCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCC
>Mature Secondary Structure 
SGQQTTTHQPWPGVIAAYRDRLPVGDDWTPVTLLEGGTPLIAAPRLSEQTGCTIHLKVE
CCCCCCCCCCCCCHHHHHHCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCEEEEEEE
GLNPTGSFKDRGMTMAVTDALARGQRAVLCASTGNTSASAAAYAARAGITCAVLIPQGKI
CCCCCCCCCCCCCEEEEHHHHHCCCEEEEEEECCCCCHHHHHHHHHCCCEEEEEECCCCC
AMGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPMISLVNSVNPVRIEGQKTAVFEI
HHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHCCCCHHHHHHCCCCEEECCCCHHHHHH
VDALGTAPHVHALPVGNAGNITAYWKGYTEYHADGLIDRLPRMLGTQAAGAAPLVLGEPV
HHHHCCCCCEEEEECCCCCCEEEEECCCHHHHHCHHHHHHHHHHCCCCCCCCCEEECCCC
SHPETIATAIRIGSPASWTSAVEAQQQSKGRFLAATDEEILAAYHLVARAEGVFVEPASA
CCHHHHHHHHCCCCCCCHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHCCCEEECCCCH
ASIAGLLKAIDGGWVARGSTVVCTITGNGLKDPDTALKDMPSVSPVPVDAVAVVEQLGLV
HHHHHHHHHHCCCEEECCCEEEEEEECCCCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]