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The map label for this gene is serC [H]

Identifier: 220917902

GI number: 220917902

Start: 3100758

End: 3101885

Strand: Reverse

Name: serC [H]

Synonym: A2cp1_2803

Alternate gene names: 220917902

Gene position: 3101885-3100758 (Counterclockwise)

Preceding gene: 220917903

Following gene: 220917899

Centisome position: 61.68

GC content: 70.57

Gene sequence:

>1128_bases
ATGCCCCGCGTGAAGAACTTCAATGCCGGCCCCGCCGCCCTCCCTCTGCCCGCGCTGGAGCGCGCCCGCGACGAGTTCCT
CGACTTCGCCGGCAGCGGCATGTCGGTGATGGAGCACTCGCACCGCGGCAAGGAGTACGAGGCGGTCCACGACGAGGCGC
TGGCGCTGCTCCGCGAGCTGCTGGGCGTGCCCGACGCCTACGACGTGCTGTTCGTGCAGGGCGGCGCGTCGCAGCTCTTC
GCGCAGATCCCGATGAACCTCGTCGAGAAGGGCCGCGGCGCCGACTACCTGGTGACCGGCGCCTGGGGCGAGAAGGCGTT
CTCCGAGGCGAAGGCCGCCACCGCGATGCTGGGCGCGTCGGCGCGCCTGGCCGGCACCACCGGCGAGGGCGAGGGCAAGG
AGAAGCGCTACGTCCGCGCGGCCACCGCCGCCGACCTCCAGGTCTCGCCCGACGCGGCGTACCTGCACCTGACCTCGAAC
GAGACCATCCACGGCGTGCAGTTCGCGGTGGACCCGGCCCGGCCGTTCCCGGACGCGGGCAAGGTCCCGCTGGTCGCCGA
CATGTCCTCCGACTTCCTGTGGAAGCCGGTGGACGTCTCGCGGTTCGGGCTGATCTACGCGGGCGCGCAGAAGAACATCG
GGCCCTCGGGCGTGGTGGTGGTGATCGTCCGCAAGGACCTGGTGGCCGCCGGCCGCAAGGACATCCCGAAGATCTTCCAG
CTCCGCACGCCGGCCGAGAACAAGTCGCTCTACAACACGCCGCCCACCTTCGGCATCTACATGATCCGCAACGTGCTCGC
GTGGCTGAAGGGGCTCGGCGGCCTGGGCGCCATGGAGCAGCGGAACCGGGCCAAGGCCGGGAAGCTGTACGGCGTCATCG
ACGCGAACCCGGGCTTCTATCGCTGCCCGGTGGAGCGTGAGAGCCGGTCGGTGATGAACGTGGTGTTCCGGCTGCCCGCC
GAGGCCGACGAGGAGCGCTTCGTGAAGGAGGCCAAGGCGAAGGGCATGGTGGGCCTGAAGGGCCACCGCTCGGTGGGCGG
CATCCGCGTGTCCACCTACAACGCGGTCGAGCCGGCCTGGCTCGACGAGCTCTGCGCGTTCATGCAGGACTTCGCGAAGC
GCGGCTAG

Upstream 100 bases:

>100_bases
CATCGCCGTCCAGTTCATGATGGACGGGCTCGCGGAAGGGTTGCCGCGGACCTTCCGGCTCCAATAAATCCCCGGTCCCC
CACCTACCCCCGAGGAGACC

Downstream 100 bases:

>100_bases
CGCCGAGCCCGCCCGCCGCGCCCGCCGGGCCCGGTCCCTCCGCGCGAGGGCCGGGCCCGCCGTCGTTCAGGGGCAGGGCT
GCGAAGGCAGCTCGGCGATC

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 375; Mature: 374

Protein sequence:

>375_residues
MPRVKNFNAGPAALPLPALERARDEFLDFAGSGMSVMEHSHRGKEYEAVHDEALALLRELLGVPDAYDVLFVQGGASQLF
AQIPMNLVEKGRGADYLVTGAWGEKAFSEAKAATAMLGASARLAGTTGEGEGKEKRYVRAATAADLQVSPDAAYLHLTSN
ETIHGVQFAVDPARPFPDAGKVPLVADMSSDFLWKPVDVSRFGLIYAGAQKNIGPSGVVVVIVRKDLVAAGRKDIPKIFQ
LRTPAENKSLYNTPPTFGIYMIRNVLAWLKGLGGLGAMEQRNRAKAGKLYGVIDANPGFYRCPVERESRSVMNVVFRLPA
EADEERFVKEAKAKGMVGLKGHRSVGGIRVSTYNAVEPAWLDELCAFMQDFAKRG

Sequences:

>Translated_375_residues
MPRVKNFNAGPAALPLPALERARDEFLDFAGSGMSVMEHSHRGKEYEAVHDEALALLRELLGVPDAYDVLFVQGGASQLF
AQIPMNLVEKGRGADYLVTGAWGEKAFSEAKAATAMLGASARLAGTTGEGEGKEKRYVRAATAADLQVSPDAAYLHLTSN
ETIHGVQFAVDPARPFPDAGKVPLVADMSSDFLWKPVDVSRFGLIYAGAQKNIGPSGVVVVIVRKDLVAAGRKDIPKIFQ
LRTPAENKSLYNTPPTFGIYMIRNVLAWLKGLGGLGAMEQRNRAKAGKLYGVIDANPGFYRCPVERESRSVMNVVFRLPA
EADEERFVKEAKAKGMVGLKGHRSVGGIRVSTYNAVEPAWLDELCAFMQDFAKRG
>Mature_374_residues
PRVKNFNAGPAALPLPALERARDEFLDFAGSGMSVMEHSHRGKEYEAVHDEALALLRELLGVPDAYDVLFVQGGASQLFA
QIPMNLVEKGRGADYLVTGAWGEKAFSEAKAATAMLGASARLAGTTGEGEGKEKRYVRAATAADLQVSPDAAYLHLTSNE
TIHGVQFAVDPARPFPDAGKVPLVADMSSDFLWKPVDVSRFGLIYAGAQKNIGPSGVVVVIVRKDLVAAGRKDIPKIFQL
RTPAENKSLYNTPPTFGIYMIRNVLAWLKGLGGLGAMEQRNRAKAGKLYGVIDANPGFYRCPVERESRSVMNVVFRLPAE
ADEERFVKEAKAKGMVGLKGHRSVGGIRVSTYNAVEPAWLDELCAFMQDFAKRG

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=375, Percent_Identity=45.0666666666667, Blast_Score=319, Evalue=2e-87,
Organism=Homo sapiens, GI10863955, Length=371, Percent_Identity=39.8921832884097, Blast_Score=262, Evalue=4e-70,
Organism=Escherichia coli, GI1787136, Length=377, Percent_Identity=42.9708222811671, Blast_Score=278, Evalue=4e-76,
Organism=Caenorhabditis elegans, GI17506897, Length=375, Percent_Identity=42.9333333333333, Blast_Score=303, Evalue=7e-83,
Organism=Saccharomyces cerevisiae, GI6324758, Length=391, Percent_Identity=36.0613810741688, Blast_Score=239, Evalue=5e-64,
Organism=Drosophila melanogaster, GI21356589, Length=375, Percent_Identity=44.5333333333333, Blast_Score=310, Evalue=1e-84,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 40612; Mature: 40481

Theoretical pI: Translated: 9.15; Mature: 9.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRVKNFNAGPAALPLPALERARDEFLDFAGSGMSVMEHSHRGKEYEAVHDEALALLREL
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
LGVPDAYDVLFVQGGASQLFAQIPMNLVEKGRGADYLVTGAWGEKAFSEAKAATAMLGAS
HCCCCCCEEEEEECCHHHHHHHCCHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCC
ARLAGTTGEGEGKEKRYVRAATAADLQVSPDAAYLHLTSNETIHGVQFAVDPARPFPDAG
CEEECCCCCCCCCHHHEEEEECCCCEEECCCCEEEEEECCCEEEEEEEEECCCCCCCCCC
KVPLVADMSSDFLWKPVDVSRFGLIYAGAQKNIGPSGVVVVIVRKDLVAAGRKDIPKIFQ
CCCEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECHHHHCCCCCCHHHHE
LRTPAENKSLYNTPPTFGIYMIRNVLAWLKGLGGLGAMEQRNRAKAGKLYGVIDANPGFY
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEECCCCEE
RCPVERESRSVMNVVFRLPAEADEERFVKEAKAKGMVGLKGHRSVGGIRVSTYNAVEPAW
ECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCCHHH
LDELCAFMQDFAKRG
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
PRVKNFNAGPAALPLPALERARDEFLDFAGSGMSVMEHSHRGKEYEAVHDEALALLREL
CCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
LGVPDAYDVLFVQGGASQLFAQIPMNLVEKGRGADYLVTGAWGEKAFSEAKAATAMLGAS
HCCCCCCEEEEEECCHHHHHHHCCHHHHHCCCCCCEEEECCCCHHHHHHHHHHHHHHCCC
ARLAGTTGEGEGKEKRYVRAATAADLQVSPDAAYLHLTSNETIHGVQFAVDPARPFPDAG
CEEECCCCCCCCCHHHEEEEECCCCEEECCCCEEEEEECCCEEEEEEEEECCCCCCCCCC
KVPLVADMSSDFLWKPVDVSRFGLIYAGAQKNIGPSGVVVVIVRKDLVAAGRKDIPKIFQ
CCCEEEECCCCCCCCCCCCCCCEEEEECCCCCCCCCCEEEEEEECHHHHCCCCCCHHHHE
LRTPAENKSLYNTPPTFGIYMIRNVLAWLKGLGGLGAMEQRNRAKAGKLYGVIDANPGFY
ECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCCCEEEEEECCCCEE
RCPVERESRSVMNVVFRLPAEADEERFVKEAKAKGMVGLKGHRSVGGIRVSTYNAVEPAW
ECCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEECCCCCCCCEEEEECCCCCHHH
LDELCAFMQDFAKRG
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA