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The map label for this gene is luxQ [H]

Identifier: 220917584

GI number: 220917584

Start: 2744082

End: 2746367

Strand: Reverse

Name: luxQ [H]

Synonym: A2cp1_2484

Alternate gene names: 220917584

Gene position: 2746367-2744082 (Counterclockwise)

Preceding gene: 220917585

Following gene: 220917583

Centisome position: 54.61

GC content: 74.15

Gene sequence:

>2286_bases
ATGAGCACGCAGCGCACGGTCGGTTCCGCATCGCTGACCGATCTCCTGTTCGACGAGGCAGCGGTCGGGCTCTGCCTGGT
GGCGCCGGACGGCACGATCGTCCGGGTCAACGCGCCCTGGCTCCGCTCGACCGGGTTCACGCACGAGCAGGTCCTGGGCG
AGCACATCGTGAGCCTGTTCCCCGGCACCCGGGACATGGCGCTCGCGATGCACGCCCGCGCCCGTGCCGGCCACCGCGTC
GAGGTCCCGCGTCACGCACAGACCGTGAACGGGCGCGAGACGTGGTGGGAGGGGAGCATCGCGCCGGTCGCGATGGAGGG
CGGGACGGGGCTGCTCATCACCGCGCGCGAGGTGAGGTCGGGGCCGGGCGAGCAGCCCCCGGGCTGCGCCTCCTGCACGG
AGGTCGTGGACCGGCTCCTGGCCTGCGTGCCGGAGGGCATCACCATCGCCACCGGACCGGACGTGGTCACGATCGCGAAC
AGCCGGTACGCGGAGGAGCGGCTGCTCGGGAGCTGGAACCGGAGCGTCGGCCTCTCGATGGAGCAGTGGCTCGCCCGCGT
CGAGCACTACCTCCCGGACGGGAAGACGCCGGCCGCGGTCGAGGATCTCCCGCTCTGGCGCGCGACCCGGCGCGGCGAGT
CGGTGCGAGACGCGGAGCTGGTCGTGAGGCGGCCCGACGGCACGCGCATGTCCGTCACCTGCAACGCCGAGCCGGTCCGG
GACGCCGCCGGCGACGTCGTGGGCGGCATCGTGGCCTGGCGCGACGTCACCGAGCAGCGGCGGCAGCAGGCGGCGCTGCG
CACCACCGAGGAGCGCTTCCGGCTGCTCGCGGAGGCGATGCCGCAGATCGTGTGCGTCCTCGCGCCCGACGGCGCGGTCG
AGCTGGTCAACCGTGCGTGGACCACCTTCTCGGGCCTGGACGTGGCCGCGACGGCCCGCACCGGGTGGGAGCGCGTCCTG
CATCCGGACGACGTGCAGGCGGCGCGCGAGTGCCGGTACCAGGCGCTGAAGCGTCTCGAGCCCCAGGACGTGGAGCTCCG
GTACCGCGCCGCGGACGGGACGTACCGCTGGTTCCTGTCGCGCCTCGCGCCCGTGGTGGAGGGCGGCCGCGTGGTGCGCT
TCATCGGCGCGGGCATGGACATCGAGCGGCGCAAGCGCGCCGAGGCGGAGCTGCGCGACGCGAACGCGAAGCTCGTCGAG
GCCGACCGGCGGAAGGACGAGTTCCTGGGGATGCTCAGCCACGAGCTGCGCAACCCGCTCGCGCCCATCCGCAACTCGAG
CTTCATCCTGCGGCACGCGGCGCCCGGGAGCGACGCGGCGAGCCGCGCGCAGCAGGTCATCGAGCGGCAGACGGGGCACC
TGACGCACCTGGTGGACGACCTGCTCGACGTGACGCGCATCTCGCGCGGCAAGATCGAGCTGCGGCGCTCGACAGTGGAT
CTGCGCGAGGTGGTCCTTCGCGCCGCGGAGGACTTCCGGCTCCCGCTGGACGATCGCGGCGTCTCGTTCCGCGCGTCGGT
CCCCGAGGCGCCGGTCCGGGCGCACGTCGACGCGACGCGGATCACGCAGGTGGTCGGGAACCTGCTCACGAACGCGGCGA
AGTTCACCCGGCGCGGGGACGAGGTGATCGTGTCGCTCACGGTCGAGGAGGGCGAGGCCGCGATCCGCGTGAGGGACACC
GGGGCCGGGATCGACCCGGCCATCCTGGCGTCGATCTTCCAGCCGTTCGTCCAGGGGGAGCGGACGCTGGCGCGGAGCGA
GGGAGGGCTCGGCCTCGGGCTGGCGCTCGTGCGGGGGATCGCCGAGCTGCACGGCGGCGCTGCCTCGGTGACGAGCGAGG
GCAAGGGCAGGGGCGCCGAGTTCCTCGTGCGGCTCCCGCTCGGCCAGGGCCAGCCGTCGGCGCCCGTGGACGGGCGAAGC
GCGGGGACGGCGCGGAGCGGCCGCAGGGTGCTGGTGGTGGACGACAACGTGGACGCCGCCGAGACGCTCGCCGAGATCGT
CACCATGCTCGGCCACACCGCCGAGATCGCGTTCGACGGGCCGGGCGCGCTCGACAAGGTGCGCACCGGCCGGCCCGACG
TGGTGCTGTGCGACCTGGGCCTGCCGGGCATGAGCGGCTACGACGTCGCGGCGGCGATCCGGGCCATGGCAGGCGAGCGC
GTGCAGCTCGTGGCGGTCTCCGGGTACGCGCAGCCCGAGGACGTGAAGCGGGCGACGGACGCCGGGTTCGACGCGCACGT
CGCCAAGCCCGCGGATCTGACCTTCCTGGAGGCGCTCCTGGCGTGA

Upstream 100 bases:

>100_bases
CGCGCCGGCGCCGGAAGCACGCGGGGACGCACCCCGGAATACACCCGTCCCGTCCCCCGGTTCGCTAGAGTTCAGCTCGC
GCCGGTACCGGGGGTACTCG

Downstream 100 bases:

>100_bases
AGGCGCCGGTCGGCACCGGGTGACGGCGGCTCGGACCGGGGCTCGTCCGCGTGGCCGTCCCCGCCGACGAGGCTGGGCTC
GCGCGAGGGCTCGTCGCAGG

Product: PAS/PAC sensor hybrid histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 761; Mature: 760

Protein sequence:

>761_residues
MSTQRTVGSASLTDLLFDEAAVGLCLVAPDGTIVRVNAPWLRSTGFTHEQVLGEHIVSLFPGTRDMALAMHARARAGHRV
EVPRHAQTVNGRETWWEGSIAPVAMEGGTGLLITAREVRSGPGEQPPGCASCTEVVDRLLACVPEGITIATGPDVVTIAN
SRYAEERLLGSWNRSVGLSMEQWLARVEHYLPDGKTPAAVEDLPLWRATRRGESVRDAELVVRRPDGTRMSVTCNAEPVR
DAAGDVVGGIVAWRDVTEQRRQQAALRTTEERFRLLAEAMPQIVCVLAPDGAVELVNRAWTTFSGLDVAATARTGWERVL
HPDDVQAARECRYQALKRLEPQDVELRYRAADGTYRWFLSRLAPVVEGGRVVRFIGAGMDIERRKRAEAELRDANAKLVE
ADRRKDEFLGMLSHELRNPLAPIRNSSFILRHAAPGSDAASRAQQVIERQTGHLTHLVDDLLDVTRISRGKIELRRSTVD
LREVVLRAAEDFRLPLDDRGVSFRASVPEAPVRAHVDATRITQVVGNLLTNAAKFTRRGDEVIVSLTVEEGEAAIRVRDT
GAGIDPAILASIFQPFVQGERTLARSEGGLGLGLALVRGIAELHGGAASVTSEGKGRGAEFLVRLPLGQGQPSAPVDGRS
AGTARSGRRVLVVDDNVDAAETLAEIVTMLGHTAEIAFDGPGALDKVRTGRPDVVLCDLGLPGMSGYDVAAAIRAMAGER
VQLVAVSGYAQPEDVKRATDAGFDAHVAKPADLTFLEALLA

Sequences:

>Translated_761_residues
MSTQRTVGSASLTDLLFDEAAVGLCLVAPDGTIVRVNAPWLRSTGFTHEQVLGEHIVSLFPGTRDMALAMHARARAGHRV
EVPRHAQTVNGRETWWEGSIAPVAMEGGTGLLITAREVRSGPGEQPPGCASCTEVVDRLLACVPEGITIATGPDVVTIAN
SRYAEERLLGSWNRSVGLSMEQWLARVEHYLPDGKTPAAVEDLPLWRATRRGESVRDAELVVRRPDGTRMSVTCNAEPVR
DAAGDVVGGIVAWRDVTEQRRQQAALRTTEERFRLLAEAMPQIVCVLAPDGAVELVNRAWTTFSGLDVAATARTGWERVL
HPDDVQAARECRYQALKRLEPQDVELRYRAADGTYRWFLSRLAPVVEGGRVVRFIGAGMDIERRKRAEAELRDANAKLVE
ADRRKDEFLGMLSHELRNPLAPIRNSSFILRHAAPGSDAASRAQQVIERQTGHLTHLVDDLLDVTRISRGKIELRRSTVD
LREVVLRAAEDFRLPLDDRGVSFRASVPEAPVRAHVDATRITQVVGNLLTNAAKFTRRGDEVIVSLTVEEGEAAIRVRDT
GAGIDPAILASIFQPFVQGERTLARSEGGLGLGLALVRGIAELHGGAASVTSEGKGRGAEFLVRLPLGQGQPSAPVDGRS
AGTARSGRRVLVVDDNVDAAETLAEIVTMLGHTAEIAFDGPGALDKVRTGRPDVVLCDLGLPGMSGYDVAAAIRAMAGER
VQLVAVSGYAQPEDVKRATDAGFDAHVAKPADLTFLEALLA
>Mature_760_residues
STQRTVGSASLTDLLFDEAAVGLCLVAPDGTIVRVNAPWLRSTGFTHEQVLGEHIVSLFPGTRDMALAMHARARAGHRVE
VPRHAQTVNGRETWWEGSIAPVAMEGGTGLLITAREVRSGPGEQPPGCASCTEVVDRLLACVPEGITIATGPDVVTIANS
RYAEERLLGSWNRSVGLSMEQWLARVEHYLPDGKTPAAVEDLPLWRATRRGESVRDAELVVRRPDGTRMSVTCNAEPVRD
AAGDVVGGIVAWRDVTEQRRQQAALRTTEERFRLLAEAMPQIVCVLAPDGAVELVNRAWTTFSGLDVAATARTGWERVLH
PDDVQAARECRYQALKRLEPQDVELRYRAADGTYRWFLSRLAPVVEGGRVVRFIGAGMDIERRKRAEAELRDANAKLVEA
DRRKDEFLGMLSHELRNPLAPIRNSSFILRHAAPGSDAASRAQQVIERQTGHLTHLVDDLLDVTRISRGKIELRRSTVDL
REVVLRAAEDFRLPLDDRGVSFRASVPEAPVRAHVDATRITQVVGNLLTNAAKFTRRGDEVIVSLTVEEGEAAIRVRDTG
AGIDPAILASIFQPFVQGERTLARSEGGLGLGLALVRGIAELHGGAASVTSEGKGRGAEFLVRLPLGQGQPSAPVDGRSA
GTARSGRRVLVVDDNVDAAETLAEIVTMLGHTAEIAFDGPGALDKVRTGRPDVVLCDLGLPGMSGYDVAAAIRAMAGERV
QLVAVSGYAQPEDVKRATDAGFDAHVAKPADLTFLEALLA

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=529, Percent_Identity=27.7882797731569, Blast_Score=133, Evalue=4e-32,
Organism=Escherichia coli, GI87081816, Length=382, Percent_Identity=30.3664921465969, Blast_Score=114, Evalue=3e-26,
Organism=Escherichia coli, GI1788713, Length=398, Percent_Identity=25.1256281407035, Blast_Score=112, Evalue=9e-26,
Organism=Escherichia coli, GI145693157, Length=261, Percent_Identity=31.4176245210728, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789149, Length=299, Percent_Identity=29.4314381270903, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1786912, Length=240, Percent_Identity=34.1666666666667, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=28.6324786324786, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI1788393, Length=287, Percent_Identity=27.5261324041812, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1790861, Length=235, Percent_Identity=30.6382978723404, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787894, Length=256, Percent_Identity=31.25, Blast_Score=87, Evalue=4e-18,
Organism=Escherichia coli, GI1790300, Length=229, Percent_Identity=32.3144104803493, Blast_Score=74, Evalue=4e-14,
Organism=Escherichia coli, GI1790346, Length=223, Percent_Identity=25.5605381165919, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1786783, Length=226, Percent_Identity=25.6637168141593, Blast_Score=73, Evalue=8e-14,
Organism=Escherichia coli, GI1790551, Length=242, Percent_Identity=26.8595041322314, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788549, Length=231, Percent_Identity=28.1385281385281, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1786600, Length=226, Percent_Identity=25.2212389380531, Blast_Score=69, Evalue=1e-12,
Organism=Saccharomyces cerevisiae, GI6322044, Length=159, Percent_Identity=32.7044025157233, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 82206; Mature: 82075

Theoretical pI: Translated: 6.27; Mature: 6.27

Prosite motif: PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTQRTVGSASLTDLLFDEAAVGLCLVAPDGTIVRVNAPWLRSTGFTHEQVLGEHIVSLF
CCCCCCCCCHHHHHHHHHHHHCCEEEECCCCEEEEEECCHHHCCCCCHHHHHHHHHHHHC
PGTRDMALAMHARARAGHRVEVPRHAQTVNGRETWWEGSIAPVAMEGGTGLLITAREVRS
CCCHHHHHHHHHHHCCCCEEECCCHHCCCCCCCCEECCCCCEEEECCCCEEEEEHHHHHC
GPGEQPPGCASCTEVVDRLLACVPEGITIATGPDVVTIANSRYAEERLLGSWNRSVGLSM
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCEEEECCCHHHHHHHHHCCCCCCCCCH
EQWLARVEHYLPDGKTPAAVEDLPLWRATRRGESVRDAELVVRRPDGTRMSVTCNAEPVR
HHHHHHHHHHCCCCCCCCCHHCCCCHHHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCH
DAAGDVVGGIVAWRDVTEQRRQQAALRTTEERFRLLAEAMPQIVCVLAPDGAVELVNRAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHH
TTFSGLDVAATARTGWERVLHPDDVQAARECRYQALKRLEPQDVELRYRAADGTYRWFLS
HHCCCCCEEECCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHH
RLAPVVEGGRVVRFIGAGMDIERRKRAEAELRDANAKLVEADRRKDEFLGMLSHELRNPL
HHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
APIRNSSFILRHAAPGSDAASRAQQVIERQTGHLTHLVDDLLDVTRISRGKIELRRSTVD
CCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEHHHHHH
LREVVLRAAEDFRLPLDDRGVSFRASVPEAPVRAHVDATRITQVVGNLLTNAAKFTRRGD
HHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCC
EVIVSLTVEEGEAAIRVRDTGAGIDPAILASIFQPFVQGERTLARSEGGLGLGLALVRGI
EEEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHH
AELHGGAASVTSEGKGRGAEFLVRLPLGQGQPSAPVDGRSAGTARSGRRVLVVDDNVDAA
HHHCCCCEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHH
ETLAEIVTMLGHTAEIAFDGPGALDKVRTGRPDVVLCDLGLPGMSGYDVAAAIRAMAGER
HHHHHHHHHHCCCEEEEECCCCCHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCC
VQLVAVSGYAQPEDVKRATDAGFDAHVAKPADLTFLEALLA
EEEEEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHC
>Mature Secondary Structure 
STQRTVGSASLTDLLFDEAAVGLCLVAPDGTIVRVNAPWLRSTGFTHEQVLGEHIVSLF
CCCCCCCCHHHHHHHHHHHHCCEEEECCCCEEEEEECCHHHCCCCCHHHHHHHHHHHHC
PGTRDMALAMHARARAGHRVEVPRHAQTVNGRETWWEGSIAPVAMEGGTGLLITAREVRS
CCCHHHHHHHHHHHCCCCEEECCCHHCCCCCCCCEECCCCCEEEECCCCEEEEEHHHHHC
GPGEQPPGCASCTEVVDRLLACVPEGITIATGPDVVTIANSRYAEERLLGSWNRSVGLSM
CCCCCCCCCHHHHHHHHHHHHHCCCCCEEECCCCEEEECCCHHHHHHHHHCCCCCCCCCH
EQWLARVEHYLPDGKTPAAVEDLPLWRATRRGESVRDAELVVRRPDGTRMSVTCNAEPVR
HHHHHHHHHHCCCCCCCCCHHCCCCHHHHHCCCCCCCCEEEEECCCCCEEEEEECCCCCH
DAAGDVVGGIVAWRDVTEQRRQQAALRTTEERFRLLAEAMPQIVCVLAPDGAVELVNRAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHHH
TTFSGLDVAATARTGWERVLHPDDVQAARECRYQALKRLEPQDVELRYRAADGTYRWFLS
HHCCCCCEEECCCCCHHHCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHH
RLAPVVEGGRVVRFIGAGMDIERRKRAEAELRDANAKLVEADRRKDEFLGMLSHELRNPL
HHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCC
APIRNSSFILRHAAPGSDAASRAQQVIERQTGHLTHLVDDLLDVTRISRGKIELRRSTVD
CCCCCCCEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCEEEHHHHHH
LREVVLRAAEDFRLPLDDRGVSFRASVPEAPVRAHVDATRITQVVGNLLTNAAKFTRRGD
HHHHHHHHHHHCCCCCCCCCCEEECCCCCCCCHHCCCHHHHHHHHHHHHHHHHHHHCCCC
EVIVSLTVEEGEAAIRVRDTGAGIDPAILASIFQPFVQGERTLARSEGGLGLGLALVRGI
EEEEEEEEECCCEEEEEECCCCCCCHHHHHHHHHHHHCCCHHHHHCCCCCHHHHHHHHHH
AELHGGAASVTSEGKGRGAEFLVRLPLGQGQPSAPVDGRSAGTARSGRRVLVVDDNVDAA
HHHCCCCEECCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCHH
ETLAEIVTMLGHTAEIAFDGPGALDKVRTGRPDVVLCDLGLPGMSGYDVAAAIRAMAGER
HHHHHHHHHHCCCEEEEECCCCCHHHHCCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCC
VQLVAVSGYAQPEDVKRATDAGFDAHVAKPADLTFLEALLA
EEEEEEECCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA