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The map label for this gene is rho [H]

Identifier: 220916372

GI number: 220916372

Start: 1418145

End: 1419326

Strand: Reverse

Name: rho [H]

Synonym: A2cp1_1266

Alternate gene names: 220916372

Gene position: 1419326-1418145 (Counterclockwise)

Preceding gene: 220916373

Following gene: 220916371

Centisome position: 28.22

GC content: 70.14

Gene sequence:

>1182_bases
ATGGGCGCCGGCGGGCAGCCCGGTGCGCCGGCCCCCGCGAACGGGACCGCGCCGCAGGGCCAGCCCGCCCCGGCCGCGCA
GGCCGAGGCGACCGAGGAGGTCGAGGGCGTGCTGCAGTTCGAGGGCAAGGGCAACGGCTGGCTCCGCGACGCGAAGCGAA
GCTACCTGCCCCAGCCGTTCGACGTCGAGGTCCCGCGCTGGCTCATCGACCGCACCCACCTGCAGCCGGGCATGCTGGTG
AAGGGCCTCGCCACGGTCCGCAACATGAAGCGGGTGCTCTCGCGGATCGACACGCTGGAGGGCACCGATCCGATGGCGGT
GGTGCGGCGCACGCACTTCCAGAACCTGACCGCCACCGACCCCACCGAGCGCCTGGTGATGGAGACCCGCTCCGACGAGC
TGATCGGGCGGGTCCTCGATCTCATCTCGCCCATCGGCCTGGGCGCCCGCGGGCTCATCACGTCGCCGCCGAAGGCCGGC
AAGACCATCATGCTGCAGCGGATCGCGCAGGCCATCATCGCGAACCGCCCGGACGTGCACCTCACGGTGCTCCTCGTGGA
CGAGCGTCCCGAGGAGGTCACCGACATGAAGCGCAACATCAAGGGCGAGGTGATCGGCTCCTCCAACGACCGCCCGACGG
AGGAGCACATCCACGTCGCCGAGATGGTGCTGGAGCGCTCGAAGCGCCTGGTCGAGGGCGGCAGGGACGTGGTGGTCCTG
CTCGACTCGATCACCCGCCTGTCGCGCGCCTACAACAAGGAGGTCGAGTCCTCCGGCCGCACCCTCACCGGCGGCGTGGA
CTCGCGCGCGCTGGAGCGCCCGAAGCGGCTGTTCGGCTCGGCGCGCAAGGCCGAGGAGGGCGGCTCGCTCACCATCATCG
CGACCGCGCTCATCGACACCGGCTCGCGCATGGACGAGGTGATCTTCGAGGAGTTCAAGGGCACCGGCAACATGGAGGTG
GTGCTCTCGCGGCAGCTCGCCGAGCGGCGCATCTTCCCGGCCATCGACATCGGCGCGTCCGGCACCCGCAAGGAGGAGAA
GCTCTTCTCGTCGAAGGACATCGAGAAGGTGCGGCGCCTCCGCGGCGCGCTCGCCTCGCTGAAGCCGGTCGAGGCCATGG
AGCGGCTGCTGAAGAAGCTCTCGGAGTTCGACTCGAACGACGAGTTCCTGCAGAGCTTCTGA

Upstream 100 bases:

>100_bases
GGGCGGCGCGCCCGGTCAGGCCGGACGGCGCCGGCGCCGTCGGCGGGGACGCCGCGGCCGCGGCGGTCAGCCGCAGCCGC
AGGGCGGCGGCCCCACGCCG

Downstream 100 bases:

>100_bases
ACGGGGCTCGCCCCGCCCCGCGGAGCGGAGCTCCGCGGGGGCCCCACCCTGCTGCGCGAGGTCCCCGCGGGCGCGGCTTC
GCCGCGTTCGGGGGCTGCGT

Product: transcription termination factor Rho

Products: NA

Alternate protein names: ATP-dependent helicase Rho [H]

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MGAGGQPGAPAPANGTAPQGQPAPAAQAEATEEVEGVLQFEGKGNGWLRDAKRSYLPQPFDVEVPRWLIDRTHLQPGMLV
KGLATVRNMKRVLSRIDTLEGTDPMAVVRRTHFQNLTATDPTERLVMETRSDELIGRVLDLISPIGLGARGLITSPPKAG
KTIMLQRIAQAIIANRPDVHLTVLLVDERPEEVTDMKRNIKGEVIGSSNDRPTEEHIHVAEMVLERSKRLVEGGRDVVVL
LDSITRLSRAYNKEVESSGRTLTGGVDSRALERPKRLFGSARKAEEGGSLTIIATALIDTGSRMDEVIFEEFKGTGNMEV
VLSRQLAERRIFPAIDIGASGTRKEEKLFSSKDIEKVRRLRGALASLKPVEAMERLLKKLSEFDSNDEFLQSF

Sequences:

>Translated_393_residues
MGAGGQPGAPAPANGTAPQGQPAPAAQAEATEEVEGVLQFEGKGNGWLRDAKRSYLPQPFDVEVPRWLIDRTHLQPGMLV
KGLATVRNMKRVLSRIDTLEGTDPMAVVRRTHFQNLTATDPTERLVMETRSDELIGRVLDLISPIGLGARGLITSPPKAG
KTIMLQRIAQAIIANRPDVHLTVLLVDERPEEVTDMKRNIKGEVIGSSNDRPTEEHIHVAEMVLERSKRLVEGGRDVVVL
LDSITRLSRAYNKEVESSGRTLTGGVDSRALERPKRLFGSARKAEEGGSLTIIATALIDTGSRMDEVIFEEFKGTGNMEV
VLSRQLAERRIFPAIDIGASGTRKEEKLFSSKDIEKVRRLRGALASLKPVEAMERLLKKLSEFDSNDEFLQSF
>Mature_392_residues
GAGGQPGAPAPANGTAPQGQPAPAAQAEATEEVEGVLQFEGKGNGWLRDAKRSYLPQPFDVEVPRWLIDRTHLQPGMLVK
GLATVRNMKRVLSRIDTLEGTDPMAVVRRTHFQNLTATDPTERLVMETRSDELIGRVLDLISPIGLGARGLITSPPKAGK
TIMLQRIAQAIIANRPDVHLTVLLVDERPEEVTDMKRNIKGEVIGSSNDRPTEEHIHVAEMVLERSKRLVEGGRDVVVLL
DSITRLSRAYNKEVESSGRTLTGGVDSRALERPKRLFGSARKAEEGGSLTIIATALIDTGSRMDEVIFEEFKGTGNMEVV
LSRQLAERRIFPAIDIGASGTRKEEKLFSSKDIEKVRRLRGALASLKPVEAMERLLKKLSEFDSNDEFLQSF

Specific function: Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template [H]

COG id: COG1158

COG function: function code K; Transcription termination factor

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Rho family [H]

Homologues:

Organism=Escherichia coli, GI1790217, Length=375, Percent_Identity=51.7333333333333, Blast_Score=360, Evalue=1e-100,

Paralogues:

None

Copy number: 300 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR011129
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR011112
- InterPro:   IPR011113
- InterPro:   IPR004665 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF07498 Rho_N; PF07497 Rho_RNA_bind [H]

EC number: NA

Molecular weight: Translated: 43212; Mature: 43081

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAGGQPGAPAPANGTAPQGQPAPAAQAEATEEVEGVLQFEGKGNGWLRDAKRSYLPQPF
CCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHCCCCCC
DVEVPRWLIDRTHLQPGMLVKGLATVRNMKRVLSRIDTLEGTDPMAVVRRTHFQNLTATD
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCC
PTERLVMETRSDELIGRVLDLISPIGLGARGLITSPPKAGKTIMLQRIAQAIIANRPDVH
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCE
LTVLLVDERPEEVTDMKRNIKGEVIGSSNDRPTEEHIHVAEMVLERSKRLVEGGRDVVVL
EEEEEECCCCHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHH
LDSITRLSRAYNKEVESSGRTLTGGVDSRALERPKRLFGSARKAEEGGSLTIIATALIDT
HHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHCCHHHHCCCCCEEEEEEEHHHC
GSRMDEVIFEEFKGTGNMEVVLSRQLAERRIFPAIDIGASGTRKEEKLFSSKDIEKVRRL
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHH
RGALASLKPVEAMERLLKKLSEFDSNDEFLQSF
HHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHCC
>Mature Secondary Structure 
GAGGQPGAPAPANGTAPQGQPAPAAQAEATEEVEGVLQFEGKGNGWLRDAKRSYLPQPF
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHCCCCCC
DVEVPRWLIDRTHLQPGMLVKGLATVRNMKRVLSRIDTLEGTDPMAVVRRTHFQNLTATD
CCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCC
PTERLVMETRSDELIGRVLDLISPIGLGARGLITSPPKAGKTIMLQRIAQAIIANRPDVH
HHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCE
LTVLLVDERPEEVTDMKRNIKGEVIGSSNDRPTEEHIHVAEMVLERSKRLVEGGRDVVVL
EEEEEECCCCHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEHH
LDSITRLSRAYNKEVESSGRTLTGGVDSRALERPKRLFGSARKAEEGGSLTIIATALIDT
HHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHHHCCHHHHCCCCCEEEEEEEHHHC
GSRMDEVIFEEFKGTGNMEVVLSRQLAERRIFPAIDIGASGTRKEEKLFSSKDIEKVRRL
CCHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCEEECCCCCCCHHHHHHHHHHHHHHHHH
RGALASLKPVEAMERLLKKLSEFDSNDEFLQSF
HHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8606169 [H]