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The map label for this gene is resE [H]

Identifier: 220916345

GI number: 220916345

Start: 1390123

End: 1391928

Strand: Reverse

Name: resE [H]

Synonym: A2cp1_1239

Alternate gene names: 220916345

Gene position: 1391928-1390123 (Counterclockwise)

Preceding gene: 220916346

Following gene: 220916325

Centisome position: 27.68

GC content: 78.35

Gene sequence:

>1806_bases
ATGCGCGCAGGGCTCCAGGGCCGGGCGCACGCGCCCCTCCTCAACGCCGCGACCCCGGGACACCCGTCGCGCACCGGGCA
GCTCCAGGCCATCACCGCCGCGCTCTCGCGCGCCGTCACCCGCGGCGACGTGGCGCGCGCGCTGGTCGAGCGGACGCTCG
ACGCCGTGGCGGCGCAGGAGGGCGCGCTGTGGCTGGTCGAGCGCGCCGGCGGGGTGGCGCGCCTCGTCCACGCGGCCGGA
CTCCCCGAGGAGGAGCGGGCGCGCCTGGAGATCCTGCCGCTGGAGCGCGGCGCCGGGCCGGTGTCCGGGAGCATGGTGGC
CTGCGAGGCGCAGTACCTGGGCAGCCGCCGGGAGCTGGCCGAGCGGTTCCCGCGCGCGCGCATGGAGCGGCTCCCGGAGC
TGGCGCTGGCGGCGGTGCCGCTCGAGGCGGAGGGGCGCTGCCTCGGGGCGCTCGCGCTCGTGTTCCACGCGCGGCGGCAT
TTCGACGAGGAGGAGCGGATCTTCCTGGCGGTGCTGGCGCGGGTGGCGGCCCAGGCGCTGGCGCGGGCACGGCTCTACGA
GTCGGAGCGGGCCGCGCGCGCGGAGGCGGAGGGCGCGCACCGGCGGGCGGCGTTCCTGGGCGAGGCGAGCGCGCTGCTCG
CGTCGTCGCTCGACTGGGAGGAGACGCTCGCCTCGGTGGCGCGGCTGGCGGTGGCGGGCGTGGCCGACTGGTGCTGGGTG
GAGCTGCCCGAGGGGCTCGCCGGCGGCGCGCCGCCGGTGGTGGTCGCCCACGTCGATCCGGCGCGCGCGGAGCTGTCCGC
CGCCTGGCGCCGGCGCTTCCCCCCCGAGCCGGACGCGCCCTCCGGGGCGCCGGCGGTGATGCGGACCGGGCGCTCCGAGC
TGTACCCGGAGCTGCCCGCCTCGCTGCTCGACGCCCTCGGGCGCGACTCCGACGCGCTCGCCGCCGACCGCGCGCTCGAG
ACCTGCTCGGCGATGGTGGTGCCGCTCTCGGCCCGCGGCCGCACGCTCGGGACGATCACGCTGGTGGCCAGCCGCGTCGA
CCGGCGCTACGGCCCGGAGGACCTCGCCATGGCGGAGGAGCTGGGGCGCCGCGCCGGCGTGGCCATGGACAACGCGCGGC
TCTACGACGAGGCACAGCGGGCCATCCGCGCGCGCGACGACGTCCTCGCGATCGTCTCGCACGACCTGAAGAACCCGCTG
GAGGCGATCTACCTCTCCTCGGCGCTGCTGCTGCGCAGCGGCGCCGCGCCCCGCCTGCGGCGGCACGCCGAGACCATCCA
GCGCTCCGCCGCCCGGATGGACCGGCTCATCCGCGAGCTGCTCGACCTGTCCAGCATCGACGCGGGCCGGCTCGTCGTGG
AGCCCCGGCCCGAGCCGCTCGACGCGGTGGTCGAGGAGGCGCTGGCCGGGCTCTCGCCGCTGGCCCTGGAGCGCGGCATC
GCGCTCGGCGCCGACACCGGCGGCGCGCGGGAGCCGGTGCCGTGCGACCGCGAGCGGATCCTGCAGGTGCTCTCGAACCT
GGTCGGGAACGCGCTCCAGTTCACCCCGCGCGGCGGGCACGTCACCGTGCGCGCCACGCTGGCGCCCACCGAGGCGCGGG
TGGAGGTGCGCGACGACGGGCCCGGCATCGCCCCGGCGCAGCTCCGGCGCGTCTTCGACCGCTACTGGAAGAGCGGCTCG
CGGCGCGGCAGCGGGCTGGGCCTGTCCATCGCGAAGGGGCTCGTGGAGGCGCACGGCGGGCGCATCGAGGTCGAGAGCCG
GCTCGGCGCGGGGAGCACGTTCCGGTTCACGTTGCCGCGGCGCTGA

Upstream 100 bases:

>100_bases
TGACGAGGCGGCCGGCGGGGTGCCCCGGGATCGCGCCGGACCCCGATTGCCCGGCCAGCGCGCGCGGCACCGGCCCGCGC
GCCGGGCTACAGGTGCTGCG

Downstream 100 bases:

>100_bases
GGCGCGCCGGCGCGCCCCGAGCTTCAGGCGAGCCGGTCGGAGAGCGCGCGGCGCAGCGGCTCGAGGTCGTCCTCCGGGGG
CAGCCAGGCGGTCACCGCCA

Product: GAF sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 601; Mature: 601

Protein sequence:

>601_residues
MRAGLQGRAHAPLLNAATPGHPSRTGQLQAITAALSRAVTRGDVARALVERTLDAVAAQEGALWLVERAGGVARLVHAAG
LPEEERARLEILPLERGAGPVSGSMVACEAQYLGSRRELAERFPRARMERLPELALAAVPLEAEGRCLGALALVFHARRH
FDEEERIFLAVLARVAAQALARARLYESERAARAEAEGAHRRAAFLGEASALLASSLDWEETLASVARLAVAGVADWCWV
ELPEGLAGGAPPVVVAHVDPARAELSAAWRRRFPPEPDAPSGAPAVMRTGRSELYPELPASLLDALGRDSDALAADRALE
TCSAMVVPLSARGRTLGTITLVASRVDRRYGPEDLAMAEELGRRAGVAMDNARLYDEAQRAIRARDDVLAIVSHDLKNPL
EAIYLSSALLLRSGAAPRLRRHAETIQRSAARMDRLIRELLDLSSIDAGRLVVEPRPEPLDAVVEEALAGLSPLALERGI
ALGADTGGAREPVPCDRERILQVLSNLVGNALQFTPRGGHVTVRATLAPTEARVEVRDDGPGIAPAQLRRVFDRYWKSGS
RRGSGLGLSIAKGLVEAHGGRIEVESRLGAGSTFRFTLPRR

Sequences:

>Translated_601_residues
MRAGLQGRAHAPLLNAATPGHPSRTGQLQAITAALSRAVTRGDVARALVERTLDAVAAQEGALWLVERAGGVARLVHAAG
LPEEERARLEILPLERGAGPVSGSMVACEAQYLGSRRELAERFPRARMERLPELALAAVPLEAEGRCLGALALVFHARRH
FDEEERIFLAVLARVAAQALARARLYESERAARAEAEGAHRRAAFLGEASALLASSLDWEETLASVARLAVAGVADWCWV
ELPEGLAGGAPPVVVAHVDPARAELSAAWRRRFPPEPDAPSGAPAVMRTGRSELYPELPASLLDALGRDSDALAADRALE
TCSAMVVPLSARGRTLGTITLVASRVDRRYGPEDLAMAEELGRRAGVAMDNARLYDEAQRAIRARDDVLAIVSHDLKNPL
EAIYLSSALLLRSGAAPRLRRHAETIQRSAARMDRLIRELLDLSSIDAGRLVVEPRPEPLDAVVEEALAGLSPLALERGI
ALGADTGGAREPVPCDRERILQVLSNLVGNALQFTPRGGHVTVRATLAPTEARVEVRDDGPGIAPAQLRRVFDRYWKSGS
RRGSGLGLSIAKGLVEAHGGRIEVESRLGAGSTFRFTLPRR
>Mature_601_residues
MRAGLQGRAHAPLLNAATPGHPSRTGQLQAITAALSRAVTRGDVARALVERTLDAVAAQEGALWLVERAGGVARLVHAAG
LPEEERARLEILPLERGAGPVSGSMVACEAQYLGSRRELAERFPRARMERLPELALAAVPLEAEGRCLGALALVFHARRH
FDEEERIFLAVLARVAAQALARARLYESERAARAEAEGAHRRAAFLGEASALLASSLDWEETLASVARLAVAGVADWCWV
ELPEGLAGGAPPVVVAHVDPARAELSAAWRRRFPPEPDAPSGAPAVMRTGRSELYPELPASLLDALGRDSDALAADRALE
TCSAMVVPLSARGRTLGTITLVASRVDRRYGPEDLAMAEELGRRAGVAMDNARLYDEAQRAIRARDDVLAIVSHDLKNPL
EAIYLSSALLLRSGAAPRLRRHAETIQRSAARMDRLIRELLDLSSIDAGRLVVEPRPEPLDAVVEEALAGLSPLALERGI
ALGADTGGAREPVPCDRERILQVLSNLVGNALQFTPRGGHVTVRATLAPTEARVEVRDDGPGIAPAQLRRVFDRYWKSGS
RRGSGLGLSIAKGLVEAHGGRIEVESRLGAGSTFRFTLPRR

Specific function: Member of the two-component regulatory system resD/resE involved in the global regulation of aerobic and anaerobic respiration. Probably phosphorylates resD [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=232, Percent_Identity=34.9137931034483, Blast_Score=125, Evalue=9e-30,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=34.8017621145374, Blast_Score=110, Evalue=3e-25,
Organism=Escherichia coli, GI145693157, Length=279, Percent_Identity=30.8243727598566, Blast_Score=107, Evalue=3e-24,
Organism=Escherichia coli, GI87081816, Length=238, Percent_Identity=33.6134453781513, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI1790436, Length=234, Percent_Identity=32.9059829059829, Blast_Score=102, Evalue=7e-23,
Organism=Escherichia coli, GI1788713, Length=234, Percent_Identity=29.9145299145299, Blast_Score=102, Evalue=8e-23,
Organism=Escherichia coli, GI1786912, Length=291, Percent_Identity=28.1786941580756, Blast_Score=101, Evalue=1e-22,
Organism=Escherichia coli, GI48994928, Length=253, Percent_Identity=28.0632411067194, Blast_Score=99, Evalue=5e-22,
Organism=Escherichia coli, GI1788393, Length=251, Percent_Identity=29.8804780876494, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1788549, Length=359, Percent_Identity=23.3983286908078, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1786783, Length=284, Percent_Identity=26.4084507042254, Blast_Score=88, Evalue=2e-18,
Organism=Escherichia coli, GI1790300, Length=248, Percent_Identity=31.8548387096774, Blast_Score=83, Evalue=5e-17,
Organism=Escherichia coli, GI1788279, Length=220, Percent_Identity=25.9090909090909, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1789808, Length=218, Percent_Identity=29.3577981651376, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790346, Length=216, Percent_Identity=26.3888888888889, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1790861, Length=237, Percent_Identity=28.6919831223629, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI87082128, Length=226, Percent_Identity=26.1061946902655, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1787894, Length=243, Percent_Identity=24.6913580246914, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64387; Mature: 64387

Theoretical pI: Translated: 8.25; Mature: 8.25

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRAGLQGRAHAPLLNAATPGHPSRTGQLQAITAALSRAVTRGDVARALVERTLDAVAAQE
CCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GALWLVERAGGVARLVHAAGLPEEERARLEILPLERGAGPVSGSMVACEAQYLGSRRELA
CCEEEEECCCCHHHHHHHCCCCHHHCCCEEEEEECCCCCCCCCCEEEEEHHHCCCHHHHH
ERFPRARMERLPELALAAVPLEAEGRCLGALALVFHARRHFDEEERIFLAVLARVAAQAL
HHHHHHHHHHCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ARARLYESERAARAEAEGAHRRAAFLGEASALLASSLDWEETLASVARLAVAGVADWCWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ELPEGLAGGAPPVVVAHVDPARAELSAAWRRRFPPEPDAPSGAPAVMRTGRSELYPELPA
CCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHCCCCCHH
SLLDALGRDSDALAADRALETCSAMVVPLSARGRTLGTITLVASRVDRRYGPEDLAMAEE
HHHHHHCCCCHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
LGRRAGVAMDNARLYDEAQRAIRARDDVLAIVSHDLKNPLEAIYLSSALLLRSGAAPRLR
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RHAETIQRSAARMDRLIRELLDLSSIDAGRLVVEPRPEPLDAVVEEALAGLSPLALERGI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHCCCHHHHHCCC
ALGADTGGAREPVPCDRERILQVLSNLVGNALQFTPRGGHVTVRATLAPTEARVEVRDDG
EECCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCEEEEEEEECCCCCEEEEECCC
PGIAPAQLRRVFDRYWKSGSRRGSGLGLSIAKGLVEAHGGRIEVESRLGAGSTFRFTLPR
CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCC
R
C
>Mature Secondary Structure
MRAGLQGRAHAPLLNAATPGHPSRTGQLQAITAALSRAVTRGDVARALVERTLDAVAAQE
CCCCCCCCCCCCEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GALWLVERAGGVARLVHAAGLPEEERARLEILPLERGAGPVSGSMVACEAQYLGSRRELA
CCEEEEECCCCHHHHHHHCCCCHHHCCCEEEEEECCCCCCCCCCEEEEEHHHCCCHHHHH
ERFPRARMERLPELALAAVPLEAEGRCLGALALVFHARRHFDEEERIFLAVLARVAAQAL
HHHHHHHHHHCHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
ARARLYESERAARAEAEGAHRRAAFLGEASALLASSLDWEETLASVARLAVAGVADWCWV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
ELPEGLAGGAPPVVVAHVDPARAELSAAWRRRFPPEPDAPSGAPAVMRTGRSELYPELPA
CCCCCCCCCCCCEEEEECCHHHHHHHHHHHHCCCCCCCCCCCCHHHHHCCHHHCCCCCHH
SLLDALGRDSDALAADRALETCSAMVVPLSARGRTLGTITLVASRVDRRYGPEDLAMAEE
HHHHHHCCCCHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHHHHHHHCCCCHHHHHHHH
LGRRAGVAMDNARLYDEAQRAIRARDDVLAIVSHDLKNPLEAIYLSSALLLRSGAAPRLR
HHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHH
RHAETIQRSAARMDRLIRELLDLSSIDAGRLVVEPRPEPLDAVVEEALAGLSPLALERGI
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCHHHHHHHHHHHCCCHHHHHCCC
ALGADTGGAREPVPCDRERILQVLSNLVGNALQFTPRGGHVTVRATLAPTEARVEVRDDG
EECCCCCCCCCCCCCCHHHHHHHHHHHHCCCEEECCCCCEEEEEEEECCCCCEEEEECCC
PGIAPAQLRRVFDRYWKSGSRRGSGLGLSIAKGLVEAHGGRIEVESRLGAGSTFRFTLPR
CCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCEEEEECCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7934829; 9384377; 8631715 [H]