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The map label for this gene is purC [H]

Identifier: 220916346

GI number: 220916346

Start: 1392130

End: 1393089

Strand: Reverse

Name: purC [H]

Synonym: A2cp1_1240

Alternate gene names: 220916346

Gene position: 1393089-1392130 (Counterclockwise)

Preceding gene: 220916348

Following gene: 220916345

Centisome position: 27.7

GC content: 68.65

Gene sequence:

>960_bases
ATGATCCCCGACGACAAGCTGCGGGCCCAGCTCCCGCACACCCTCCAGCAGCTCGACCTCCCCGGTCTCGGCGAGCTGTA
CCGGGGGAAGGTCCGCGACAACTACAGCCGCGGCGACCGGATCGTCATGGTCACGACCGACCGGATCTCGGCCTTCGACC
ACGTGCTCGGCACCATCCCGTTCAAGGGCGAGGTGCTGTCGCGGCTCACCGCGTTCTGGTTCGACAAGGTGAAGGACATC
GCGCCGACGCACATCGTCGAGGTGCCGGATCCGAGCGTGATGGTGGTGAAGCGCGCCAAGGCGCTGCCCATCGAGATCGT
CATCCGCGGCTACGTCACCGGCTCGCTCTGGCGCGACTACCAGGCCGGCAAGGCCGACTACGGCATCTCCTGGCCGGCCG
GGCTGCGCAAGGACCAGCGGTTCGACCAGCCCATCATCACGCCCTCGACCAAGGCCGAGTACGGCAAGCACGACGAGCCC
ATCGGCGAGGCCGAGATCCTGAAGCAGGGTCTGGTGACGCCGGACGTCTGGAAGGAGGCCACCGCCGTCGCGCGGCGGCT
GTTCCAGCGCGGCCAGGAGTGGGCGCGGACGCGCGGCCTCATCCTCGTGGACACGAAGTACGAGATGGGGATCGCCGACG
GCAAGCTGGTGGTCATCGACGAGATCCACACCCCGGACAGCTCGCGCTACTGGGTGGCGGACGGCTACGAGGAGCGCTTC
GCGCGGGGCGAGGACCAGGAGATGCTGGACAAGGAGAACATCCGGCAGTGGCTCATCAAGGAGCACGGGTTCTCCGGGCA
CGGCACCCCGCCCCCGCTCACCGACGACGTGCGGGTGATGCTGGCGCGCAAGTACGTCGAGGTCTTCGAGAAGCTCACCG
GCGAGACGTTCGCGTCGGAGGTCGGCTCGGTCGCCGCCCGCATCGAGCGGAACCTCCGCGCCACGGGTCACCTCGCCTGA

Upstream 100 bases:

>100_bases
CGGGCGGCGGCGCCGACGTTGTCGGCGCTCTGCGGCCGGTGGAGCACGAGGCGGATTTTTCCCGGGTGCATGTGCGCCCG
CCACGTATAACATCCCGCCC

Downstream 100 bases:

>100_bases
GCCTCGCCGGGGCCGGCGGCCGCTCCCCGGCCGGCCGCCCCGCAGCGGAGTGGCGCCGGGCCCGCGCCCGCGCGCCGGGA
GGCGCTCCGCCGCCCGCCCC

Product: phosphoribosylaminoimidazole-succinocarboxamide synthase

Products: NA

Alternate protein names: SAICAR synthetase [H]

Number of amino acids: Translated: 319; Mature: 319

Protein sequence:

>319_residues
MIPDDKLRAQLPHTLQQLDLPGLGELYRGKVRDNYSRGDRIVMVTTDRISAFDHVLGTIPFKGEVLSRLTAFWFDKVKDI
APTHIVEVPDPSVMVVKRAKALPIEIVIRGYVTGSLWRDYQAGKADYGISWPAGLRKDQRFDQPIITPSTKAEYGKHDEP
IGEAEILKQGLVTPDVWKEATAVARRLFQRGQEWARTRGLILVDTKYEMGIADGKLVVIDEIHTPDSSRYWVADGYEERF
ARGEDQEMLDKENIRQWLIKEHGFSGHGTPPPLTDDVRVMLARKYVEVFEKLTGETFASEVGSVAARIERNLRATGHLA

Sequences:

>Translated_319_residues
MIPDDKLRAQLPHTLQQLDLPGLGELYRGKVRDNYSRGDRIVMVTTDRISAFDHVLGTIPFKGEVLSRLTAFWFDKVKDI
APTHIVEVPDPSVMVVKRAKALPIEIVIRGYVTGSLWRDYQAGKADYGISWPAGLRKDQRFDQPIITPSTKAEYGKHDEP
IGEAEILKQGLVTPDVWKEATAVARRLFQRGQEWARTRGLILVDTKYEMGIADGKLVVIDEIHTPDSSRYWVADGYEERF
ARGEDQEMLDKENIRQWLIKEHGFSGHGTPPPLTDDVRVMLARKYVEVFEKLTGETFASEVGSVAARIERNLRATGHLA
>Mature_319_residues
MIPDDKLRAQLPHTLQQLDLPGLGELYRGKVRDNYSRGDRIVMVTTDRISAFDHVLGTIPFKGEVLSRLTAFWFDKVKDI
APTHIVEVPDPSVMVVKRAKALPIEIVIRGYVTGSLWRDYQAGKADYGISWPAGLRKDQRFDQPIITPSTKAEYGKHDEP
IGEAEILKQGLVTPDVWKEATAVARRLFQRGQEWARTRGLILVDTKYEMGIADGKLVVIDEIHTPDSSRYWVADGYEERF
ARGEDQEMLDKENIRQWLIKEHGFSGHGTPPPLTDDVRVMLARKYVEVFEKLTGETFASEVGSVAARIERNLRATGHLA

Specific function: De novo purine biosynthesis; seventh step. [C]

COG id: COG0152

COG function: function code F; Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the SAICAR synthetase family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6319326, Length=299, Percent_Identity=35.1170568561873, Blast_Score=185, Evalue=8e-48,

Paralogues:

None

Copy number: 1680 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 13,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013816
- InterPro:   IPR001636
- InterPro:   IPR018236 [H]

Pfam domain/function: PF01259 SAICAR_synt [H]

EC number: =6.3.2.6 [H]

Molecular weight: Translated: 36107; Mature: 36107

Theoretical pI: Translated: 6.74; Mature: 6.74

Prosite motif: PS01057 SAICAR_SYNTHETASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPDDKLRAQLPHTLQQLDLPGLGELYRGKVRDNYSRGDRIVMVTTDRISAFDHVLGTIP
CCCCHHHHHHHHHHHHHCCCCCCHHHHHCHHCCCCCCCCEEEEEECCHHHHHHHHHHCCC
FKGEVLSRLTAFWFDKVKDIAPTHIVEVPDPSVMVVKRAKALPIEIVIRGYVTGSLWRDY
CCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEHHCCCCCEEEEEEHHHHHHHHHHH
QAGKADYGISWPAGLRKDQRFDQPIITPSTKAEYGKHDEPIGEAEILKQGLVTPDVWKEA
CCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHH
TAVARRLFQRGQEWARTRGLILVDTKYEMGIADGKLVVIDEIHTPDSSRYWVADGYEERF
HHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCEEEECCHHHHH
ARGEDQEMLDKENIRQWLIKEHGFSGHGTPPPLTDDVRVMLARKYVEVFEKLTGETFASE
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHH
VGSVAARIERNLRATGHLA
HHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MIPDDKLRAQLPHTLQQLDLPGLGELYRGKVRDNYSRGDRIVMVTTDRISAFDHVLGTIP
CCCCHHHHHHHHHHHHHCCCCCCHHHHHCHHCCCCCCCCEEEEEECCHHHHHHHHHHCCC
FKGEVLSRLTAFWFDKVKDIAPTHIVEVPDPSVMVVKRAKALPIEIVIRGYVTGSLWRDY
CCHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEHHCCCCCEEEEEEHHHHHHHHHHH
QAGKADYGISWPAGLRKDQRFDQPIITPSTKAEYGKHDEPIGEAEILKQGLVTPDVWKEA
CCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCHHHHHHH
TAVARRLFQRGQEWARTRGLILVDTKYEMGIADGKLVVIDEIHTPDSSRYWVADGYEERF
HHHHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCEEEEEECCCCCCCCEEEECCHHHHH
ARGEDQEMLDKENIRQWLIKEHGFSGHGTPPPLTDDVRVMLARKYVEVFEKLTGETFASE
CCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHH
VGSVAARIERNLRATGHLA
HHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA