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The map label for this gene is mltC [H]

Identifier: 220905341

GI number: 220905341

Start: 2502079

End: 2503158

Strand: Reverse

Name: mltC [H]

Synonym: Ddes_2079

Alternate gene names: 220905341

Gene position: 2503158-2502079 (Counterclockwise)

Preceding gene: 220905350

Following gene: 220905340

Centisome position: 87.11

GC content: 62.04

Gene sequence:

>1080_bases
ATGAAGCGCCATAAAACCCTTGCCATCCTTGCCGGTTGCCTTGGCAGTACATTGCTGCTCCTGGGCTTGCTGGCGGGTTT
TGTGCCGCAGCATGAAGGGTATGAGGTGCGCCGCCGCGCAAGCCCTGTTGTGGTCAGCCTGCGGCCCGAAGACATGCCTG
TTCCCATCGTTCCGCAGGGCGACGGTTCGCGCCAGTGGTCCTTGCGCCGCGCGGCATCGCCCGTGGTGGCGCCGGTGTCT
TTGGCCGATGCTTCGTCACGGGCTGAGACAGAGGACGGCGACGGTTTTTTCAGCCAGGTTCCGGCAGGCACGGGGCAGTT
GGCTTCTCTGCTGGCGCTTGATGGATTTTCCATGCCGCCGCTGCTGGCTGTACAGCCCTCGCGCTTCGGGGACGCTGTTG
ACGCCAGGGGGCTGCCCCTGCGCTGGCTGGCTGCCGAAACATTGCTTGAGGGCTACAGCCCCCTGCCGCCGCGTACCGGC
AAGACCGCCGGGCAGGGCGGTACAAGGGGTATGTCTGCGGCCAATGCCTTTTACGGTAACGATATGCTCCCGCCCAGGGC
GCGGCGCTACCAGCAGATAGTGGAAAGCTTTGCCGGGCGCTATAATCTGAGCACCGAACTTGTGTACGCCATTATCCACA
GCGAAAGCTCGTTTTCCCCCACCCTTGTGAGCCACAAGTCGGCCATGGGCCTGATGCAGATTTTGCCGGACACGGCCGGG
GGCGAGGTGCACCGTTATCTGTACGGGCGCACGGGCGACGTAAGCTTTGAAGACCTGCGCGTGCCGGAAACAAATATCCG
CTACGGTACGACCTATCTGCACATTCTGCTCACGCGGTATTTCGCCGGGGTGCACGACCCGAGGGCGCGTGAATACTGTG
CCGTAGCCGCATACAATATGGGGCCGAACCGCTTTTTGCGGCTTTTCGGCAACAGTCCGGAAGAAGCTGTTGACGCCATT
AACGCCCTGACAGCAGAACAGTTGTACGAAGACCTGACCATCCGCCTGCCCGTGGCCGAAACCCGCGCCTATGTCGCCAA
GGTCGCCAGGATGAAAGGGCATTACGCCGCGCTGCAATAA

Upstream 100 bases:

>100_bases
GGAGCGCTCGTTTTGCCCGGTTGCGTTGTTGTGCGGCCTGCGTCGTGTGACGGCGCGTCGGCAAAGAACAGGCCAAGGCC
ATCAGATTTGAGGATTTTTC

Downstream 100 bases:

>100_bases
AGGGTTTTGCCGTAATCCTGTCTGCTGCTGCGCGGGACAGGCACAAGGTTGTAGCCCGGCTTTGGCCGTTGGCGAAGGGC
TTGCGGATGAAGACGGCGGC

Product: lytic transglycosylase

Products: N-Acetylmuramic Acid Residues; N-Acetylglucosamine Residues [C]

Alternate protein names: Murein hydrolase C [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MKRHKTLAILAGCLGSTLLLLGLLAGFVPQHEGYEVRRRASPVVVSLRPEDMPVPIVPQGDGSRQWSLRRAASPVVAPVS
LADASSRAETEDGDGFFSQVPAGTGQLASLLALDGFSMPPLLAVQPSRFGDAVDARGLPLRWLAAETLLEGYSPLPPRTG
KTAGQGGTRGMSAANAFYGNDMLPPRARRYQQIVESFAGRYNLSTELVYAIIHSESSFSPTLVSHKSAMGLMQILPDTAG
GEVHRYLYGRTGDVSFEDLRVPETNIRYGTTYLHILLTRYFAGVHDPRAREYCAVAAYNMGPNRFLRLFGNSPEEAVDAI
NALTAEQLYEDLTIRLPVAETRAYVAKVARMKGHYAALQ

Sequences:

>Translated_359_residues
MKRHKTLAILAGCLGSTLLLLGLLAGFVPQHEGYEVRRRASPVVVSLRPEDMPVPIVPQGDGSRQWSLRRAASPVVAPVS
LADASSRAETEDGDGFFSQVPAGTGQLASLLALDGFSMPPLLAVQPSRFGDAVDARGLPLRWLAAETLLEGYSPLPPRTG
KTAGQGGTRGMSAANAFYGNDMLPPRARRYQQIVESFAGRYNLSTELVYAIIHSESSFSPTLVSHKSAMGLMQILPDTAG
GEVHRYLYGRTGDVSFEDLRVPETNIRYGTTYLHILLTRYFAGVHDPRAREYCAVAAYNMGPNRFLRLFGNSPEEAVDAI
NALTAEQLYEDLTIRLPVAETRAYVAKVARMKGHYAALQ
>Mature_359_residues
MKRHKTLAILAGCLGSTLLLLGLLAGFVPQHEGYEVRRRASPVVVSLRPEDMPVPIVPQGDGSRQWSLRRAASPVVAPVS
LADASSRAETEDGDGFFSQVPAGTGQLASLLALDGFSMPPLLAVQPSRFGDAVDARGLPLRWLAAETLLEGYSPLPPRTG
KTAGQGGTRGMSAANAFYGNDMLPPRARRYQQIVESFAGRYNLSTELVYAIIHSESSFSPTLVSHKSAMGLMQILPDTAG
GEVHRYLYGRTGDVSFEDLRVPETNIRYGTTYLHILLTRYFAGVHDPRAREYCAVAAYNMGPNRFLRLFGNSPEEAVDAI
NALTAEQLYEDLTIRLPVAETRAYVAKVARMKGHYAALQ

Specific function: Murein-degrading enzyme. May play a role in recycling of muropeptides during cell elongation and/or cell division [H]

COG id: COG0741

COG function: function code M; Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains)

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transglycosylase slt family [H]

Homologues:

Organism=Escherichia coli, GI87082191, Length=237, Percent_Identity=33.7552742616034, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI87081855, Length=163, Percent_Identity=33.1288343558282, Blast_Score=98, Evalue=7e-22,
Organism=Escherichia coli, GI87082441, Length=166, Percent_Identity=29.5180722891566, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008258
- InterPro:   IPR000189 [H]

Pfam domain/function: PF01464 SLT [H]

EC number: 3.2.1.- [C]

Molecular weight: Translated: 39036; Mature: 39036

Theoretical pI: Translated: 8.57; Mature: 8.57

Prosite motif: PS00922 TRANSGLYCOSYLASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRHKTLAILAGCLGSTLLLLGLLAGFVPQHEGYEVRRRASPVVVSLRPEDMPVPIVPQG
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEECCCCCCCEEEECC
DGSRQWSLRRAASPVVAPVSLADASSRAETEDGDGFFSQVPAGTGQLASLLALDGFSMPP
CCCCCHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCC
LLAVQPSRFGDAVDARGLPLRWLAAETLLEGYSPLPPRTGKTAGQGGTRGMSAANAFYGN
EEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCC
DMLPPRARRYQQIVESFAGRYNLSTELVYAIIHSESSFSPTLVSHKSAMGLMQILPDTAG
CCCCHHHHHHHHHHHHHHCCCCCCHHEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCC
GEVHRYLYGRTGDVSFEDLRVPETNIRYGTTYLHILLTRYFAGVHDPRAREYCAVAAYNM
CCEEHHEECCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHEEEEEEECC
GPNRFLRLFGNSPEEAVDAINALTAEQLYEDLTIRLPVAETRAYVAKVARMKGHYAALQ
CHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHCCCHHCCC
>Mature Secondary Structure
MKRHKTLAILAGCLGSTLLLLGLLAGFVPQHEGYEVRRRASPVVVSLRPEDMPVPIVPQG
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEECCCCCCCEEEECC
DGSRQWSLRRAASPVVAPVSLADASSRAETEDGDGFFSQVPAGTGQLASLLALDGFSMPP
CCCCCHHHHHHCCCCEEEEECCCCCCCCCCCCCCCHHHHCCCCHHHHHHHHHHCCCCCCC
LLAVQPSRFGDAVDARGLPLRWLAAETLLEGYSPLPPRTGKTAGQGGTRGMSAANAFYGN
EEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCC
DMLPPRARRYQQIVESFAGRYNLSTELVYAIIHSESSFSPTLVSHKSAMGLMQILPDTAG
CCCCHHHHHHHHHHHHHHCCCCCCHHEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCC
GEVHRYLYGRTGDVSFEDLRVPETNIRYGTTYLHILLTRYFAGVHDPRAREYCAVAAYNM
CCEEHHEECCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHEEEEEEECC
GPNRFLRLFGNSPEEAVDAINALTAEQLYEDLTIRLPVAETRAYVAKVARMKGHYAALQ
CHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEEECHHHHHHHHHHHHHHCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Muramic Acid [C]

Specific reaction: Cleavage Of The Beta-1,4-Glycosidic Bond Between N-Acetylmuramic Acid And N-Acetylglucosamine Residues, Thereby Conserving The Energy In A Newly Synthesized 1,6-Anhydrobond In The Muramic Acid Residue. [C]

General reaction: Cleavage Of The Beta-1,4-Glycosidic Bond [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA