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The map label for this gene is cynT [H]

Identifier: 220905299

GI number: 220905299

Start: 2449642

End: 2450343

Strand: Reverse

Name: cynT [H]

Synonym: Ddes_2037

Alternate gene names: 220905299

Gene position: 2450343-2449642 (Counterclockwise)

Preceding gene: 220905305

Following gene: 220905294

Centisome position: 85.28

GC content: 51.71

Gene sequence:

>702_bases
GTGCGCCTGCCGCCTGAATGGCTGTGGAATGAAGGGCTGCGTAACCCCAACGGAGGATCGTTGATGAAGAATGTTGAAAG
CCTGTTACAGGGCAACGAGCTGTTTCAGAAAAATTATTTCAGAAAAAATGAATCCCAGCTTCTGGATCTGGTCAGCAGCG
GGCAGCACCCCAAGGCGCTTTTTATCGGTTGCGCCGACTCCCGGGTTATTCCCTCCCTCATAACCAACGCGCCTCCGGGG
CAGCTTTTTGTCTTGCGCAATGTGGGCAACTTTGTAGCTCCCTATAAGCCGGACGAAGATTATCACGCGACGGCTTCCGG
CATTGAATACGCGGTCACCACGCTGAACATCTCGGAAATAATCATCTGCGGGCATACCCACTGTGGCGCCATTGAGGCGC
TGTACAAAGACATCAACGGCAAGCAGCTTATCCATACGAAAAAATGGCTGTCCCTCGGCAAGAAAGCCAAGGACCTTGCC
CTGCTGGCCCTGGGCAAAAATGCCGACAGGGAAAAACTGCTGCGCCTGACCGAAAAACTTTCCATCATATTCCAGATCGA
AAACCTGCTCACCTATCCCTATGTCAGACGCAAGGTAAACAAGGGTACGCTGCATATCCACGGCTGGCTCTATCACATCG
AGTCCGGCGAAATGGAATATTACGATCCTGATGAACACGAGTTTCTTACACTGAACAAGTGA

Upstream 100 bases:

>100_bases
ATGATTTGGAAGCAGCGTGATGATACCCCGGCCCTGCCGGGGAATGCGCCCCCCCCTTTACGGGCCGTGCCGTCTTTCCG
CAGAGGACGGCATCCACGGG

Downstream 100 bases:

>100_bases
GTTCGGGCGCTCGTCGCGCAGGGGATGCGCCTGCGGCAACTGCTTGCCTTTGATCGGGGATAGCTCAAACGTAAGCTGCG
CTGTCCGCCGGTCTCTATGC

Product: carbonate dehydratase

Products: NA

Alternate protein names: Carbonate dehydratase [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MRLPPEWLWNEGLRNPNGGSLMKNVESLLQGNELFQKNYFRKNESQLLDLVSSGQHPKALFIGCADSRVIPSLITNAPPG
QLFVLRNVGNFVAPYKPDEDYHATASGIEYAVTTLNISEIIICGHTHCGAIEALYKDINGKQLIHTKKWLSLGKKAKDLA
LLALGKNADREKLLRLTEKLSIIFQIENLLTYPYVRRKVNKGTLHIHGWLYHIESGEMEYYDPDEHEFLTLNK

Sequences:

>Translated_233_residues
MRLPPEWLWNEGLRNPNGGSLMKNVESLLQGNELFQKNYFRKNESQLLDLVSSGQHPKALFIGCADSRVIPSLITNAPPG
QLFVLRNVGNFVAPYKPDEDYHATASGIEYAVTTLNISEIIICGHTHCGAIEALYKDINGKQLIHTKKWLSLGKKAKDLA
LLALGKNADREKLLRLTEKLSIIFQIENLLTYPYVRRKVNKGTLHIHGWLYHIESGEMEYYDPDEHEFLTLNK
>Mature_233_residues
MRLPPEWLWNEGLRNPNGGSLMKNVESLLQGNELFQKNYFRKNESQLLDLVSSGQHPKALFIGCADSRVIPSLITNAPPG
QLFVLRNVGNFVAPYKPDEDYHATASGIEYAVTTLNISEIIICGHTHCGAIEALYKDINGKQLIHTKKWLSLGKKAKDLA
LLALGKNADREKLLRLTEKLSIIFQIENLLTYPYVRRKVNKGTLHIHGWLYHIESGEMEYYDPDEHEFLTLNK

Specific function: Reversible Hydration Of Carbon Dioxide. Carbon Dioxide Formed In The Bicarbonate-Dependent Decomposition Of Cyanate By Cyanase (Cyns) Diffuses Out Of The Cell Faster Than It Would Be Hydrated To Bicarbonate, So The Apparent Function Of This Enzyme Is To C

COG id: COG0288

COG function: function code P; Carbonic anhydrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-class carbonic anhydrase family [H]

Homologues:

Organism=Escherichia coli, GI1786534, Length=207, Percent_Identity=33.8164251207729, Blast_Score=139, Evalue=1e-34,
Organism=Escherichia coli, GI1786318, Length=202, Percent_Identity=30.6930693069307, Blast_Score=88, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI115532990, Length=247, Percent_Identity=26.3157894736842, Blast_Score=86, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324292, Length=203, Percent_Identity=27.0935960591133, Blast_Score=74, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24645213, Length=241, Percent_Identity=26.5560165975104, Blast_Score=91, Evalue=5e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001765
- InterPro:   IPR015892 [H]

Pfam domain/function: PF00484 Pro_CA [H]

EC number: =4.2.1.1 [H]

Molecular weight: Translated: 26484; Mature: 26484

Theoretical pI: Translated: 8.10; Mature: 8.10

Prosite motif: PS00704 PROK_CO2_ANHYDRASE_1 ; PS00705 PROK_CO2_ANHYDRASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLPPEWLWNEGLRNPNGGSLMKNVESLLQGNELFQKNYFRKNESQLLDLVSSGQHPKAL
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHCCCCCCEE
FIGCADSRVIPSLITNAPPGQLFVLRNVGNFVAPYKPDEDYHATASGIEYAVTTLNISEI
EEECCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEE
IICGHTHCGAIEALYKDINGKQLIHTKKWLSLGKKAKDLALLALGKNADREKLLRLTEKL
EEECCCCCHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHH
SIIFQIENLLTYPYVRRKVNKGTLHIHGWLYHIESGEMEYYDPDEHEFLTLNK
HHEEEHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCEECCCCCCCCEEEECC
>Mature Secondary Structure
MRLPPEWLWNEGLRNPNGGSLMKNVESLLQGNELFQKNYFRKNESQLLDLVSSGQHPKAL
CCCCHHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHCCCCCCEE
FIGCADSRVIPSLITNAPPGQLFVLRNVGNFVAPYKPDEDYHATASGIEYAVTTLNISEI
EEECCCCCHHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEEE
IICGHTHCGAIEALYKDINGKQLIHTKKWLSLGKKAKDLALLALGKNADREKLLRLTEKL
EEECCCCCHHHHHHHHCCCCCEEEHHHHHHHHCCCCCCEEEEEECCCCCHHHHHHHHHHH
SIIFQIENLLTYPYVRRKVNKGTLHIHGWLYHIESGEMEYYDPDEHEFLTLNK
HHEEEHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCEECCCCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]