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The map label for this gene is dpaL [H]

Identifier: 220905305

GI number: 220905305

Start: 2456114

End: 2457346

Strand: Reverse

Name: dpaL [H]

Synonym: Ddes_2043

Alternate gene names: 220905305

Gene position: 2457346-2456114 (Counterclockwise)

Preceding gene: 220905306

Following gene: 220905299

Centisome position: 85.52

GC content: 63.02

Gene sequence:

>1233_bases
GTGAATACTGTCAGCTATTGTCCCAACAGCCTGTGCACAGGCACTGCCGATGCGGCGGATGTTGAGGTCTATGGGCCGGA
AGTTGCCCGTGTTGCCCGCGCCTTTCATCAGGGCTTTGACCGCTATGCGCCCACGCCGCTGGTACGACTGAAAAATCTTG
CTCATGAACTGGGGCTTGGCGAAATTCTGGTCAAGGACGAGTCGCAACGCTTTGGCCTCAATGCTTTCAAGGTGCTGGGC
TGTTCTTACGCGGTGGCGCGTTATCTGGCCCGGCGGCTTGATTTGCCCATGAGCCGGGTCAGCCCGCAACTGCTGCGCTC
CGCCGAGGTGCATGAGCAGCTGGGAAAGATTACCCTGGTGACGGCTACTGACGGCAATCACGGCCGGGGCGTAGCCTGGA
CTGCCCAGCAGATCGGCATGGGGGCCACGGTCTTCATGCCCGCAGGCTCCGCGCCGGTCAGGGCTGAAAACATCCGCAAG
ACCGGAGCGCAATGCACCATAACCGACCTCAACTATGATGATACCGTGCGTCTGGCCATGCAGCACGCGCAGGAAACGGA
CGGCGTGCTTGTGCAGGACACGGCCTGGGACGGGTATGAAGAGGTGCCGCTCTGGATCATGCAGGGGTATACGACCCTGG
CTCTGGAAGCAGACGAACAGTGGCGGGATTGCGGACTGCGCCCGCCGACCCATATTTTTCTGCAGGCCGGGGTGGGGTCC
TTTGCGGCGGCGGTGCTTGGGTATTTTGCTGCCGTGTGGGGTGATGCCGCGCCGCAGGTCATTACTGTGGAGCCGCAGGC
TGCCGACTGCTTTTTCCGTTCCTTCATGGCCGGAAACAGCGCTCCCCGCGCGGTCAGCGGCCATATGCGAACCATCATGG
CAGGGCTTGCCTGCGGTGAGCCGAGCAGCCTGTGCTGGCCCCTTTTGCGCGATAGGGCCGTGGGTGGCCTATCCTGCCAC
GATGTGGTGGCCGCCAACGGCATGCGCATCCTTGCCGCACCGCTGCCGGGCGACAGCCCCGTGTGCAGTGGCGAATCCGG
GGCGGCTCCCCTGGGGGCCATCGAGCAGATCATGAAAAATCCGCAGATGCAGGACGTCCGTCAGGCCTTGAGGCTGGACG
CAGCCTCCCGCATTTTGCTTTTCAGCACCGAAGGGGATACCTCGCCCGAACTGTACCGCCAGATTGTCTGGTACGGCCGC
TGCGCCGGGGTGGAGGCAGGATGGCCGTCATAA

Upstream 100 bases:

>100_bases
AGAAGATATTGTCGCCATGCTGCGGCGGGTCTGCCCGCTGCCGGGCACAAGCCTCGGTATATATATCAATCGGGCAGCCA
CGCCCTACAGGAGAGCAGCC

Downstream 100 bases:

>100_bases
CCAGAGCATTTTTACTTGAAAATGCTTTGGCGGCTGCGCGAGCAGGCGCAACGTATTTGCGTTGTCAAACGCCGTAGCGG
GTGTGCTTTGCCTGTGAGAA

Product: diaminopropionate ammonia-lyase

Products: NA

Alternate protein names: Diaminopropionatase; Alpha,beta-diaminopropionate ammonia-lyase [H]

Number of amino acids: Translated: 410; Mature: 410

Protein sequence:

>410_residues
MNTVSYCPNSLCTGTADAADVEVYGPEVARVARAFHQGFDRYAPTPLVRLKNLAHELGLGEILVKDESQRFGLNAFKVLG
CSYAVARYLARRLDLPMSRVSPQLLRSAEVHEQLGKITLVTATDGNHGRGVAWTAQQIGMGATVFMPAGSAPVRAENIRK
TGAQCTITDLNYDDTVRLAMQHAQETDGVLVQDTAWDGYEEVPLWIMQGYTTLALEADEQWRDCGLRPPTHIFLQAGVGS
FAAAVLGYFAAVWGDAAPQVITVEPQAADCFFRSFMAGNSAPRAVSGHMRTIMAGLACGEPSSLCWPLLRDRAVGGLSCH
DVVAANGMRILAAPLPGDSPVCSGESGAAPLGAIEQIMKNPQMQDVRQALRLDAASRILLFSTEGDTSPELYRQIVWYGR
CAGVEAGWPS

Sequences:

>Translated_410_residues
MNTVSYCPNSLCTGTADAADVEVYGPEVARVARAFHQGFDRYAPTPLVRLKNLAHELGLGEILVKDESQRFGLNAFKVLG
CSYAVARYLARRLDLPMSRVSPQLLRSAEVHEQLGKITLVTATDGNHGRGVAWTAQQIGMGATVFMPAGSAPVRAENIRK
TGAQCTITDLNYDDTVRLAMQHAQETDGVLVQDTAWDGYEEVPLWIMQGYTTLALEADEQWRDCGLRPPTHIFLQAGVGS
FAAAVLGYFAAVWGDAAPQVITVEPQAADCFFRSFMAGNSAPRAVSGHMRTIMAGLACGEPSSLCWPLLRDRAVGGLSCH
DVVAANGMRILAAPLPGDSPVCSGESGAAPLGAIEQIMKNPQMQDVRQALRLDAASRILLFSTEGDTSPELYRQIVWYGR
CAGVEAGWPS
>Mature_410_residues
MNTVSYCPNSLCTGTADAADVEVYGPEVARVARAFHQGFDRYAPTPLVRLKNLAHELGLGEILVKDESQRFGLNAFKVLG
CSYAVARYLARRLDLPMSRVSPQLLRSAEVHEQLGKITLVTATDGNHGRGVAWTAQQIGMGATVFMPAGSAPVRAENIRK
TGAQCTITDLNYDDTVRLAMQHAQETDGVLVQDTAWDGYEEVPLWIMQGYTTLALEADEQWRDCGLRPPTHIFLQAGVGS
FAAAVLGYFAAVWGDAAPQVITVEPQAADCFFRSFMAGNSAPRAVSGHMRTIMAGLACGEPSSLCWPLLRDRAVGGLSCH
DVVAANGMRILAAPLPGDSPVCSGESGAAPLGAIEQIMKNPQMQDVRQALRLDAASRILLFSTEGDTSPELYRQIVWYGR
CAGVEAGWPS

Specific function: Catalyzes the alpha,beta-elimination reaction of both L- and D-alpha,beta-diaminopropionate, the most suitable substrates to form pyruvate and ammonia. The L- and D-isomers of serine are also degraded, though slowly; it is the only serine dehydratase whic

COG id: COG1171

COG function: function code E; Threonine dehydratase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789235, Length=380, Percent_Identity=50.2631578947368, Blast_Score=370, Evalue=1e-104,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010081
- InterPro:   IPR019871
- InterPro:   IPR001926 [H]

Pfam domain/function: PF00291 PALP [H]

EC number: =4.3.1.15 [H]

Molecular weight: Translated: 44116; Mature: 44116

Theoretical pI: Translated: 5.41; Mature: 5.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVSYCPNSLCTGTADAADVEVYGPEVARVARAFHQGFDRYAPTPLVRLKNLAHELGLG
CCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
EILVKDESQRFGLNAFKVLGCSYAVARYLARRLDLPMSRVSPQLLRSAEVHEQLGKITLV
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCEEEE
TATDGNHGRGVAWTAQQIGMGATVFMPAGSAPVRAENIRKTGAQCTITDLNYDDTVRLAM
EECCCCCCCCEEEEHHHHCCCEEEEEECCCCCCCHHHHHHCCCEEEEEECCCCHHHHHHH
QHAQETDGVLVQDTAWDGYEEVPLWIMQGYTTLALEADEQWRDCGLRPPTHIFLQAGVGS
HHHHCCCCEEEEECCCCCHHHCCEEEECCCEEEEEECCHHHHHCCCCCCCEEEEECCHHH
FAAAVLGYFAAVWGDAAPQVITVEPQAADCFFRSFMAGNSAPRAVSGHMRTIMAGLACGE
HHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
PSSLCWPLLRDRAVGGLSCHDVVAANGMRILAAPLPGDSPVCSGESGAAPLGAIEQIMKN
CCHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCC
PQMQDVRQALRLDAASRILLFSTEGDTSPELYRQIVWYGRCAGVEAGWPS
CCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MNTVSYCPNSLCTGTADAADVEVYGPEVARVARAFHQGFDRYAPTPLVRLKNLAHELGLG
CCCCCCCCCCCCCCCCCCCCEEEECHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCC
EILVKDESQRFGLNAFKVLGCSYAVARYLARRLDLPMSRVSPQLLRSAEVHEQLGKITLV
EEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCHHHHHHHHHHHHHCCEEEE
TATDGNHGRGVAWTAQQIGMGATVFMPAGSAPVRAENIRKTGAQCTITDLNYDDTVRLAM
EECCCCCCCCEEEEHHHHCCCEEEEEECCCCCCCHHHHHHCCCEEEEEECCCCHHHHHHH
QHAQETDGVLVQDTAWDGYEEVPLWIMQGYTTLALEADEQWRDCGLRPPTHIFLQAGVGS
HHHHCCCCEEEEECCCCCHHHCCEEEECCCEEEEEECCHHHHHCCCCCCCEEEEECCHHH
FAAAVLGYFAAVWGDAAPQVITVEPQAADCFFRSFMAGNSAPRAVSGHMRTIMAGLACGE
HHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCC
PSSLCWPLLRDRAVGGLSCHDVVAANGMRILAAPLPGDSPVCSGESGAAPLGAIEQIMKN
CCHHHHHHHHHHCCCCCCHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHHCC
PQMQDVRQALRLDAASRILLFSTEGDTSPELYRQIVWYGRCAGVEAGWPS
CCHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677609; 3275662 [H]