Click here to switch to the map view.

The map label for this gene is galE [H]

Identifier: 220905212

GI number: 220905212

Start: 2350958

End: 2351944

Strand: Reverse

Name: galE [H]

Synonym: Ddes_1950

Alternate gene names: 220905212

Gene position: 2351944-2350958 (Counterclockwise)

Preceding gene: 220905213

Following gene: 220905211

Centisome position: 81.85

GC content: 58.76

Gene sequence:

>987_bases
ATGCCCATTCTGGTTTGCGGCGGAGCCGGATATATCGGCTCCCACAATGTGCGTTCCCTGTTGGCGCGCGGTGAAGAAGT
CGTTGTCATAGACAATTTTTTTACCGGTCACCGCGCTTCATTGCCTGACGGCGTTACCCTGTACGAAGGAGATATTCGCC
AGGGCGAACTGCTGGACAGGATTTTTTCCGAACACCGGGTGGATGCCGTGCTGCACTTTGCCGCCAGCTCGCTGGTGGGC
GAGAGCATGGAACAGCCGCTGAAATATTTTCACAACAATGTCCACGGCATGCAAAGCCTGCTTGAGGCTATGGTGCGCAA
CCATGTGGACAAGATCGTATTTTCCTCATCCGCGGCTGTTTACGGCGAACAGGACAATGTACCCATCAGCGAAGATGCGG
CCCTCAGCCCCACCAATCCCTATGGCGAAAGCAAGCTCATTATGGAGCGCATGATGCACTGGGTGGGCAAGGCGCACGGC
ATACGTTTTGTGAGCCTGCGCTACTTCAACGTGGGAGGTGCCTGGCCCGGCGGTATTATTGGTGAAGACCACAGGCCGGA
AAGCCACCTCATTCCTCTCATCCTGCAGGTTCCGCTGGGCAGGCGCGAAACCGTGACCATCTTCGGCAATGACTATCCCA
CGCCCGACGGTACGTGTATTCGCGACTATATCGGCGTTATGGATCTGGCGGATGCACACATGCGCGCCCTGGACTACCTG
CGTGCGGGCGGCGGCAGCGAGGTATGCAATCTTGGCAACGGCAAGGGTTTCAGCGTGCGCGAAATGGTCGCCGCTGCCTG
CCGGGTGACAGGGCACGACATCGGCGTGACCATGGCCACCCGCCGTTATGGCGATCCGGCCCGGCTGGTGGCCTCGGCCG
ACCGTGCCAGGGAACTGCTGGGGTGGGAAGCCAAGGCGGGTATTGACGACATCATTGCTTCCGCCTGGGAATGGCATAAA
AATCATCCTGACGGCTTTTCCGCCTGA

Upstream 100 bases:

>100_bases
TCATGGCGGGGCTTGCCATGACGGCAATTGTTGTGCAAAAAGCGAAACCTTGTTGGCGCGGAGTCCGCGCCGGACAGCTT
TCAACAAAAGAGACATGCCA

Downstream 100 bases:

>100_bases
GGCCTGCGCGGCCTTGCATAAAAACGGCAACAGTGCGCCTGCTCCGTTTTTTCGGGGTGGGCGCACTGTTTTTGCCTCCG
TTTGTCTCCGCGCCGCGCAG

Product: UDP-glucose 4-epimerase

Products: NA

Alternate protein names: Galactowaldenase; UDP-galactose 4-epimerase [H]

Number of amino acids: Translated: 328; Mature: 327

Protein sequence:

>328_residues
MPILVCGGAGYIGSHNVRSLLARGEEVVVIDNFFTGHRASLPDGVTLYEGDIRQGELLDRIFSEHRVDAVLHFAASSLVG
ESMEQPLKYFHNNVHGMQSLLEAMVRNHVDKIVFSSSAAVYGEQDNVPISEDAALSPTNPYGESKLIMERMMHWVGKAHG
IRFVSLRYFNVGGAWPGGIIGEDHRPESHLIPLILQVPLGRRETVTIFGNDYPTPDGTCIRDYIGVMDLADAHMRALDYL
RAGGGSEVCNLGNGKGFSVREMVAAACRVTGHDIGVTMATRRYGDPARLVASADRARELLGWEAKAGIDDIIASAWEWHK
NHPDGFSA

Sequences:

>Translated_328_residues
MPILVCGGAGYIGSHNVRSLLARGEEVVVIDNFFTGHRASLPDGVTLYEGDIRQGELLDRIFSEHRVDAVLHFAASSLVG
ESMEQPLKYFHNNVHGMQSLLEAMVRNHVDKIVFSSSAAVYGEQDNVPISEDAALSPTNPYGESKLIMERMMHWVGKAHG
IRFVSLRYFNVGGAWPGGIIGEDHRPESHLIPLILQVPLGRRETVTIFGNDYPTPDGTCIRDYIGVMDLADAHMRALDYL
RAGGGSEVCNLGNGKGFSVREMVAAACRVTGHDIGVTMATRRYGDPARLVASADRARELLGWEAKAGIDDIIASAWEWHK
NHPDGFSA
>Mature_327_residues
PILVCGGAGYIGSHNVRSLLARGEEVVVIDNFFTGHRASLPDGVTLYEGDIRQGELLDRIFSEHRVDAVLHFAASSLVGE
SMEQPLKYFHNNVHGMQSLLEAMVRNHVDKIVFSSSAAVYGEQDNVPISEDAALSPTNPYGESKLIMERMMHWVGKAHGI
RFVSLRYFNVGGAWPGGIIGEDHRPESHLIPLILQVPLGRRETVTIFGNDYPTPDGTCIRDYIGVMDLADAHMRALDYLR
AGGGSEVCNLGNGKGFSVREMVAAACRVTGHDIGVTMATRRYGDPARLVASADRARELLGWEAKAGIDDIIASAWEWHKN
HPDGFSA

Specific function: Galactose metabolism; third step. [C]

COG id: COG1087

COG function: function code M; UDP-glucose 4-epimerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sugar epimerase family [H]

Homologues:

Organism=Homo sapiens, GI56237023, Length=340, Percent_Identity=43.2352941176471, Blast_Score=248, Evalue=7e-66,
Organism=Homo sapiens, GI56118217, Length=340, Percent_Identity=43.2352941176471, Blast_Score=248, Evalue=7e-66,
Organism=Homo sapiens, GI189083684, Length=340, Percent_Identity=43.2352941176471, Blast_Score=248, Evalue=7e-66,
Organism=Homo sapiens, GI42516563, Length=323, Percent_Identity=25.6965944272446, Blast_Score=98, Evalue=9e-21,
Organism=Homo sapiens, GI7657641, Length=335, Percent_Identity=24.4776119402985, Blast_Score=92, Evalue=8e-19,
Organism=Escherichia coli, GI1786974, Length=336, Percent_Identity=41.9642857142857, Blast_Score=259, Evalue=2e-70,
Organism=Escherichia coli, GI1788353, Length=355, Percent_Identity=27.887323943662, Blast_Score=95, Evalue=6e-21,
Organism=Escherichia coli, GI48994969, Length=349, Percent_Identity=26.3610315186246, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1790049, Length=270, Percent_Identity=27.7777777777778, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1788365, Length=343, Percent_Identity=22.7405247813411, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71982035, Length=347, Percent_Identity=40.9221902017291, Blast_Score=252, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI71982038, Length=349, Percent_Identity=40.6876790830946, Blast_Score=251, Evalue=2e-67,
Organism=Caenorhabditis elegans, GI17539532, Length=329, Percent_Identity=24.9240121580547, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17568069, Length=269, Percent_Identity=28.996282527881, Blast_Score=76, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319493, Length=343, Percent_Identity=41.6909620991254, Blast_Score=258, Evalue=8e-70,
Organism=Drosophila melanogaster, GI19923002, Length=343, Percent_Identity=42.8571428571429, Blast_Score=262, Evalue=3e-70,
Organism=Drosophila melanogaster, GI21356223, Length=324, Percent_Identity=26.8518518518519, Blast_Score=110, Evalue=2e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR005886
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =5.1.3.2 [H]

Molecular weight: Translated: 35879; Mature: 35748

Theoretical pI: Translated: 6.10; Mature: 6.10

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPILVCGGAGYIGSHNVRSLLARGEEVVVIDNFFTGHRASLPDGVTLYEGDIRQGELLDR
CCEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEECCCCHHHHHHH
IFSEHRVDAVLHFAASSLVGESMEQPLKYFHNNVHGMQSLLEAMVRNHVDKIVFSSSAAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
YGEQDNVPISEDAALSPTNPYGESKLIMERMMHWVGKAHGIRFVSLRYFNVGGAWPGGII
ECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCCC
GEDHRPESHLIPLILQVPLGRRETVTIFGNDYPTPDGTCIRDYIGVMDLADAHMRALDYL
CCCCCCCHHHEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RAGGGSEVCNLGNGKGFSVREMVAAACRVTGHDIGVTMATRRYGDPARLVASADRARELL
HCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEHHCCCCHHHHHHHHHHHHHHH
GWEAKAGIDDIIASAWEWHKNHPDGFSA
CCCHHCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
PILVCGGAGYIGSHNVRSLLARGEEVVVIDNFFTGHRASLPDGVTLYEGDIRQGELLDR
CEEEECCCCCCCCHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCEEEECCCCHHHHHHH
IFSEHRVDAVLHFAASSLVGESMEQPLKYFHNNVHGMQSLLEAMVRNHVDKIVFSSSAAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEE
YGEQDNVPISEDAALSPTNPYGESKLIMERMMHWVGKAHGIRFVSLRYFNVGGAWPGGII
ECCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCEEEEEEEEEECCCCCCCCCC
GEDHRPESHLIPLILQVPLGRRETVTIFGNDYPTPDGTCIRDYIGVMDLADAHMRALDYL
CCCCCCCHHHEEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
RAGGGSEVCNLGNGKGFSVREMVAAACRVTGHDIGVTMATRRYGDPARLVASADRARELL
HCCCCCCEEECCCCCCCCHHHHHHHHHHHCCCCCCEEEEHHCCCCHHHHHHHHHHHHHHH
GWEAKAGIDDIIASAWEWHKNHPDGFSA
CCCHHCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]