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The map label for this gene is trpD [H]

Identifier: 220904857

GI number: 220904857

Start: 1911589

End: 1913181

Strand: Reverse

Name: trpD [H]

Synonym: Ddes_1591

Alternate gene names: 220904857

Gene position: 1913181-1911589 (Counterclockwise)

Preceding gene: 220904858

Following gene: 220904856

Centisome position: 66.58

GC content: 60.77

Gene sequence:

>1593_bases
ATGTTTCTTCTTATAGATAATTACGATTCTTTTACATATAATCTGGTACAGGCCTTTCACGCCCTGGGGCACAAGCCTGT
AGTTATGACCAACGACGACCCCGCAGTGCTTGGCATGGCTGAAAATCCGGACCTTGCCCTGGTCTGTATTTCTCCCGGGC
CGGGGCATCCTTCCAAAGCGGGTTTTTGCCCCGAATTTCTCGGGCGTCTTGATCCGCGTATTCCGGTGCTTGGCGTGTGC
CTGGGGCATCAGTTGCTTGGCCTGCGCGCCGGGGCGCGGGTGGAAGTTGGCCCCTGCATCATGCACGGCAAGCAGTCTGA
AATAGTGCATGACGGCACGGGCCTGTTCTCCGGCCTGCCCAATCCCATGCGGGTAGGGCGTTACCATTCCCTTGTGGTAC
GTGCCGACGAAGATGCCGAAAATCCGCGTTTTACCGTCACAGCCCGTGGCCCCGAAGGCGAGGTTATGGCCCTGCGTTAT
AATGACCGCCCCTGGGTGGGGGTGCAGTTTCATCCCGAGTCGGTACTCACGCCCGAAGGGCTGCGCCTGCTGGGCAATTT
TCCGCAGATGATCATGGATGCCGGTGGGCCAGCATCCAACTTTGCGGATATTCTCGAGCGGCTGGCCCGTGGAGAAGACC
TCAGCGCTGAGATGGCTGCCGCAGGTTTTGCCGCCCTTATGGACGGGAAAATGACTTCGGCCCAGGCCGGGAGCTTTCTC
ATGGGGCTGCGCATGAAAGGTGAAAGCGCTCTGGAACTGGCTCACGCCACACGCGCCGCCCTTGCTCGTGCCGTGCGCGT
GGACGGCGTTTCGGGTACGACCATTGACGTGGTGGGTACAGGCGGCGACGGGCGCAACTCTTTTAACTGCTCCACGGCCA
CATCGCTTGTTCTGGCGGGCATGGGCTACAAGGTGGTCAAACACGGCGGCCGCGCCGTTTCTTCAAAATGCGGCAGCGCC
GACGCCCTTGAAGCTCTCGGTATCGCGCTGGACGAAAACCCCGCTTCGGTGGCCGAAATGGTCAGAAAGCGCAATTTTGC
CTTTTTGTTCGCGCCGCACTTTCATCCCTCCTTTGCCAATATCGGTCCTGTGCGCAAGGAACTGGGGGTGCGCACACTCT
TCAACATACTGGGACCAATGATCAATCCAGCCCGGCCCAGCCATCTGCTCATGGGTGTGGCCCGGCCGGAACTGGTGGAT
CTTGTGGCCGAAACCCTGCTTCAGGGACCGTTGTACCGGGCAGCCGTGGTTTGCGGCGCGGGCGACTATGACGAGATCAC
ACCCATTGGTCCCGCGCGCATGGCCTTGCTGCATGCCGGTTCTGTGACGCCTATGACGCTTGACCCCCGCGACTTCGGCA
TCCTGCCGTGCACCGTGGAAGATCTGGCCGTGGACGGCAAGGATGAGGCCGTGGCCATGCTCAGGGGGATACTCGATGGT
GAAGGCCCGCGCGCCATGCTGGACATGGTGGCCCTCAATGTGGGGCTGGCGGTGTACCTGCTGGAAGAAAACATGGACAT
GGCCCTGTGCATGGCGCGCGCGCGCGAAGCCGTAAGCGGAGGCTTTGGCAGGAAGGTGCTGCATGCTGCTTGA

Upstream 100 bases:

>100_bases
GGAGGAATCGTTCATGATTCGGACCCGGATATGGAATGGAAAGAAGTTTGCAATAAGTCAGCCATTATGCGCCTTGCCCT
GCGAACGGAGGACGAAGAGT

Downstream 100 bases:

>100_bases
GCGTTTCATCAAGGCCAAGACGGCCGAAGTTGAGGGCCTGCGCCGTCTGGCGGAGCAGGGTAAAATCCCCGCGCCGCTTG
ATGTGCCGCGGCCGGAGTTT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MFLLIDNYDSFTYNLVQAFHALGHKPVVMTNDDPAVLGMAENPDLALVCISPGPGHPSKAGFCPEFLGRLDPRIPVLGVC
LGHQLLGLRAGARVEVGPCIMHGKQSEIVHDGTGLFSGLPNPMRVGRYHSLVVRADEDAENPRFTVTARGPEGEVMALRY
NDRPWVGVQFHPESVLTPEGLRLLGNFPQMIMDAGGPASNFADILERLARGEDLSAEMAAAGFAALMDGKMTSAQAGSFL
MGLRMKGESALELAHATRAALARAVRVDGVSGTTIDVVGTGGDGRNSFNCSTATSLVLAGMGYKVVKHGGRAVSSKCGSA
DALEALGIALDENPASVAEMVRKRNFAFLFAPHFHPSFANIGPVRKELGVRTLFNILGPMINPARPSHLLMGVARPELVD
LVAETLLQGPLYRAAVVCGAGDYDEITPIGPARMALLHAGSVTPMTLDPRDFGILPCTVEDLAVDGKDEAVAMLRGILDG
EGPRAMLDMVALNVGLAVYLLEENMDMALCMARAREAVSGGFGRKVLHAA

Sequences:

>Translated_530_residues
MFLLIDNYDSFTYNLVQAFHALGHKPVVMTNDDPAVLGMAENPDLALVCISPGPGHPSKAGFCPEFLGRLDPRIPVLGVC
LGHQLLGLRAGARVEVGPCIMHGKQSEIVHDGTGLFSGLPNPMRVGRYHSLVVRADEDAENPRFTVTARGPEGEVMALRY
NDRPWVGVQFHPESVLTPEGLRLLGNFPQMIMDAGGPASNFADILERLARGEDLSAEMAAAGFAALMDGKMTSAQAGSFL
MGLRMKGESALELAHATRAALARAVRVDGVSGTTIDVVGTGGDGRNSFNCSTATSLVLAGMGYKVVKHGGRAVSSKCGSA
DALEALGIALDENPASVAEMVRKRNFAFLFAPHFHPSFANIGPVRKELGVRTLFNILGPMINPARPSHLLMGVARPELVD
LVAETLLQGPLYRAAVVCGAGDYDEITPIGPARMALLHAGSVTPMTLDPRDFGILPCTVEDLAVDGKDEAVAMLRGILDG
EGPRAMLDMVALNVGLAVYLLEENMDMALCMARAREAVSGGFGRKVLHAA
>Mature_530_residues
MFLLIDNYDSFTYNLVQAFHALGHKPVVMTNDDPAVLGMAENPDLALVCISPGPGHPSKAGFCPEFLGRLDPRIPVLGVC
LGHQLLGLRAGARVEVGPCIMHGKQSEIVHDGTGLFSGLPNPMRVGRYHSLVVRADEDAENPRFTVTARGPEGEVMALRY
NDRPWVGVQFHPESVLTPEGLRLLGNFPQMIMDAGGPASNFADILERLARGEDLSAEMAAAGFAALMDGKMTSAQAGSFL
MGLRMKGESALELAHATRAALARAVRVDGVSGTTIDVVGTGGDGRNSFNCSTATSLVLAGMGYKVVKHGGRAVSSKCGSA
DALEALGIALDENPASVAEMVRKRNFAFLFAPHFHPSFANIGPVRKELGVRTLFNILGPMINPARPSHLLMGVARPELVD
LVAETLLQGPLYRAAVVCGAGDYDEITPIGPARMALLHAGSVTPMTLDPRDFGILPCTVEDLAVDGKDEAVAMLRGILDG
EGPRAMLDMVALNVGLAVYLLEENMDMALCMARAREAVSGGFGRKVLHAA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787517, Length=486, Percent_Identity=41.9753086419753, Blast_Score=318, Evalue=7e-88,
Organism=Escherichia coli, GI1789760, Length=189, Percent_Identity=46.031746031746, Blast_Score=152, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6322638, Length=232, Percent_Identity=37.0689655172414, Blast_Score=127, Evalue=6e-30,
Organism=Saccharomyces cerevisiae, GI6320561, Length=316, Percent_Identity=29.1139240506329, Blast_Score=120, Evalue=8e-28,
Organism=Saccharomyces cerevisiae, GI6324361, Length=243, Percent_Identity=30.8641975308642, Blast_Score=85, Evalue=3e-17,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072 [H]

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3 [H]

EC number: =2.4.2.18 [H]

Molecular weight: Translated: 56136; Mature: 56136

Theoretical pI: Translated: 5.99; Mature: 5.99

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
4.7 %Met     (Translated Protein)
6.4 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
4.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFLLIDNYDSFTYNLVQAFHALGHKPVVMTNDDPAVLGMAENPDLALVCISPGPGHPSKA
CEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCEEEEEECCCCCCCCCC
GFCPEFLGRLDPRIPVLGVCLGHQLLGLRAGARVEVGPCIMHGKQSEIVHDGTGLFSGLP
CCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCEEECCCCCCEEECCCHHHCCCC
NPMRVGRYHSLVVRADEDAENPRFTVTARGPEGEVMALRYNDRPWVGVQFHPESVLTPEG
CHHHCCCEEEEEEEECCCCCCCEEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCCHHH
LRLLGNFPQMIMDAGGPASNFADILERLARGEDLSAEMAAAGFAALMDGKMTSAQAGSFL
HHHHCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEE
MGLRMKGESALELAHATRAALARAVRVDGVSGTTIDVVGTGGDGRNSFNCSTATSLVLAG
EEEEECCCHHHHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHC
MGYKVVKHGGRAVSSKCGSADALEALGIALDENPASVAEMVRKRNFAFLFAPHFHPSFAN
CCHHHHHCCCHHHHHCCCCHHHHHHHCEEECCCHHHHHHHHHHCCEEEEEECCCCCCCCC
IGPVRKELGVRTLFNILGPMINPARPSHLLMGVARPELVDLVAETLLQGPLYRAAVVCGA
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCCHHHHHHHHHHHHCCCCCEEEEEECC
GDYDEITPIGPARMALLHAGSVTPMTLDPRDFGILPCTVEDLAVDGKDEAVAMLRGILDG
CCCCCCCCCCHHHHHEEECCCCCCEEECCCCCCEEEEEHHHHCCCCCHHHHHHHHHHHCC
EGPRAMLDMVALNVGLAVYLLEENMDMALCMARAREAVSGGFGRKVLHAA
CCHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHCC
>Mature Secondary Structure
MFLLIDNYDSFTYNLVQAFHALGHKPVVMTNDDPAVLGMAENPDLALVCISPGPGHPSKA
CEEEEECCCCHHHHHHHHHHHCCCCCEEEECCCCEEEEECCCCCEEEEEECCCCCCCCCC
GFCPEFLGRLDPRIPVLGVCLGHQLLGLRAGARVEVGPCIMHGKQSEIVHDGTGLFSGLP
CCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEEEECCEEECCCCCCEEECCCHHHCCCC
NPMRVGRYHSLVVRADEDAENPRFTVTARGPEGEVMALRYNDRPWVGVQFHPESVLTPEG
CHHHCCCEEEEEEEECCCCCCCEEEEEEECCCCCEEEEEECCCCEEEEEECCCCCCCHHH
LRLLGNFPQMIMDAGGPASNFADILERLARGEDLSAEMAAAGFAALMDGKMTSAQAGSFL
HHHHCCCHHHHHCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEE
MGLRMKGESALELAHATRAALARAVRVDGVSGTTIDVVGTGGDGRNSFNCSTATSLVLAG
EEEEECCCHHHHHHHHHHHHHHHHHEECCCCCCEEEEEECCCCCCCCCCCHHHHHHHHHC
MGYKVVKHGGRAVSSKCGSADALEALGIALDENPASVAEMVRKRNFAFLFAPHFHPSFAN
CCHHHHHCCCHHHHHCCCCHHHHHHHCEEECCCHHHHHHHHHHCCEEEEEECCCCCCCCC
IGPVRKELGVRTLFNILGPMINPARPSHLLMGVARPELVDLVAETLLQGPLYRAAVVCGA
CCHHHHHHHHHHHHHHHHHCCCCCCCCHHEEECCCHHHHHHHHHHHHCCCCCEEEEEECC
GDYDEITPIGPARMALLHAGSVTPMTLDPRDFGILPCTVEDLAVDGKDEAVAMLRGILDG
CCCCCCCCCCHHHHHEEECCCCCCEEECCCCCCEEEEEHHHHCCCCCHHHHHHHHHHHCC
EGPRAMLDMVALNVGLAVYLLEENMDMALCMARAREAVSGGFGRKVLHAA
CCHHHHHHHHHHHHCEEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA