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The map label for this gene is bioA [H]

Identifier: 220904568

GI number: 220904568

Start: 1537611

End: 1539737

Strand: Reverse

Name: bioA [H]

Synonym: Ddes_1300

Alternate gene names: 220904568

Gene position: 1539737-1537611 (Counterclockwise)

Preceding gene: 220904569

Following gene: 220904565

Centisome position: 53.59

GC content: 59.43

Gene sequence:

>2127_bases
GTGACCAGAGCTGTTGAAAAATGTTGCCCTGACCACATGTGCGAACCTTTGCGCGGCGTTTTTGTGGCGGGATCAGGTAC
GGACGTGGGTAAAACAGTGTGCGCGGGCGCTTTGTTGCGCGCCTTGCGGCAGATGCGTATGCCCGTTCAGGCTGTCAAAC
CGGTGCAGACAGGGATTCCTGCAAGCGCACATGCCGTTTCAGCACAATCTGATGCGGCCGTGTATACAGCCGCAGTGGCG
GGAGTCGCCTCCACAGGCAGACTGCAGCCTGCGGCAATGCTGCATTGTTTTGAACTGCCCGCCTCACCACACCTTGCCGC
TGCGCGGGAAGGAAAAAAATTGGATTGCATGAGCCTGCGTGGGGATATTCTTGCCCACTGGGCGACTGTTCCGGCCCGGG
CCCTTTTGCTGGAAGGAGCAGGCGGCCTGCGTGTGCCGCTCAACGAAGATGAAGATATGCTGGATCTTATGGCAGTTCTG
GGCTTGCCTGTTTTTCTTGTGGGCGGCAACTACCTTGGCTGCCTGAACCATATTCTTCTTTCCATTGATGCGCTGCGTCA
CAGCGGGCTTGAACTGGCAGGGCTTGCGCTTGTTCCTTCGGTCGACCCCGATGCCGGATGCCCCGGAGTTGATATCGCAG
CCATGCTGGCGGACAACGCCCGTATTCTGCGTCACCGGCTTGGTCGGACCGGCAGTGATGCGCCGGTGGTAGAATTGCCG
CGTCTGAAAAATCTGGACGAAGGTGGGTGGGACAAACTGGCCCGTTTGTTGACTCCTGTGGCCTTGCGCATGGCTCAGGC
ATGGTCCGAACCTGCCCTCGCCGGCGGGCAGGCATCTTCGGAAGAGCAGAATCTGGTACGCAGGGACAGGGCAGCAGTCT
GGCATCCTTATGCCTCAGCCCTGGATTTTCCTCCGCTTAATGCCGTGCGACGCACCTGGGCAAACCGTATTGTTCTGGCA
GACGGCAGAGAGCTTGTGGACGGCATGTCTTCGTGGTGGGCGGCTGTGCACGGTTACAACAACCCGCACCTGCTTGACGC
CCTGCGCGTACAGGCCGGGCGCATGCCTCACGTCATGTTCGGGGGGCTTACGCATGAGCCTGCCGTGGCATTGGCCGAAA
GGCTGCTCGGGCTTATGCCCGAAGGTCTTGAGCGCGTCTTTTTTTCCGATTCCGGCTCTGTAGCCGTTGACGTTGCTCTC
AAAATGGCGCTGCAATACCAGTATGCCCGGGGGGAAACCGGGCGTACCTGTTTTCTGACTCCGCGCGGCGGCTATCACGG
TGATACTATCGGGGCCATGTCTGTATGTGATCCTGTGACCGGTATGCACGGTCTGTTTGCAGGCATGCTGCCTCGTCAGC
TTTTTATGGAGCAGCCTTCCTGCGGATTTGATCAGCCCTTTGACCCGGCCAGTCTGGACAATGCTCGTCAGATGCTTGAA
CAGCACGGCAAAAAGATCGCTGCCGTTATTCTTGAGCCTGTGGTACAGGGAGCAGGGGGCATGTGGTTTTATCATCCGGA
GTATCTGCGCGGGTTGGCGCAGTTGTGCCGCGATGCCGATACGCTGCTTATCTTTGATGAAATTGCCACTGGCTTCGGAC
GCACGGGCAAAATGTTCGCGGCTGAATGGGCCGGCATCAGTCCGGATATCCTTTGCTGCGGCAAAGCTCTTACGGGGGGG
GTACTCACCCTTGCCGCCACAGTGTGCAACAAGCGTGTTGCCGAGGGCATCTGCCGGGATGGCGGGGTGTTCATGCACGG
GCCTACCTTCATGGCCAATGCTCTGGCCTGCGCTGTGGCGGGGGCCAGTCTGGACCTGCTTTCTTCCGGCAGATGGCGGC
AACAGGTGGGAGATATTGAGCGCGACCTGCGCACAGGTCTTGCCCCGTGCAGGGATATGCCCGGCGTGGCCCATGTTCGT
GTGTTGGGCGCAATAGGGGTGGTGGAGATGAAGGAGCCTGTCAACACGCGCACGCTACAGGCTTTTTTTGTGGATCAGGG
GGTGTGGCTGCGTCCCTTTAACCGGCTTATCTACCTTATGCCGCCTTATGTGACTCCCGCCGGGGATACACTCCGGCTGT
GTGCTGCGGTAGAGGAAGCCCTGCGCCAGGGGGCGCATTTGTCGTGA

Upstream 100 bases:

>100_bases
GGGGCGAATGCTCTGATGACTGGCGATTACCTGACTACTCAGGGCCGCGGCCTGGTTGATGATCTTGCCATGATTGATTC
TCTTGGTCTGGAGGTTGATT

Downstream 100 bases:

>100_bases
TATTCCTTCTGATCTATATTGCGGTACTGTTTCTTCTGGCCTGGATTACGGCGCGGCGCGCCCCCGATAAGGAAACGTAC
TTTGTCAATGGCCGGCGCAG

Product: adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Products: NA

Alternate protein names: 7,8-diamino-pelargonic acid aminotransferase; DAPA AT; DAPA aminotransferase; Diaminopelargonic acid synthase [H]

Number of amino acids: Translated: 708; Mature: 707

Protein sequence:

>708_residues
MTRAVEKCCPDHMCEPLRGVFVAGSGTDVGKTVCAGALLRALRQMRMPVQAVKPVQTGIPASAHAVSAQSDAAVYTAAVA
GVASTGRLQPAAMLHCFELPASPHLAAAREGKKLDCMSLRGDILAHWATVPARALLLEGAGGLRVPLNEDEDMLDLMAVL
GLPVFLVGGNYLGCLNHILLSIDALRHSGLELAGLALVPSVDPDAGCPGVDIAAMLADNARILRHRLGRTGSDAPVVELP
RLKNLDEGGWDKLARLLTPVALRMAQAWSEPALAGGQASSEEQNLVRRDRAAVWHPYASALDFPPLNAVRRTWANRIVLA
DGRELVDGMSSWWAAVHGYNNPHLLDALRVQAGRMPHVMFGGLTHEPAVALAERLLGLMPEGLERVFFSDSGSVAVDVAL
KMALQYQYARGETGRTCFLTPRGGYHGDTIGAMSVCDPVTGMHGLFAGMLPRQLFMEQPSCGFDQPFDPASLDNARQMLE
QHGKKIAAVILEPVVQGAGGMWFYHPEYLRGLAQLCRDADTLLIFDEIATGFGRTGKMFAAEWAGISPDILCCGKALTGG
VLTLAATVCNKRVAEGICRDGGVFMHGPTFMANALACAVAGASLDLLSSGRWRQQVGDIERDLRTGLAPCRDMPGVAHVR
VLGAIGVVEMKEPVNTRTLQAFFVDQGVWLRPFNRLIYLMPPYVTPAGDTLRLCAAVEEALRQGAHLS

Sequences:

>Translated_708_residues
MTRAVEKCCPDHMCEPLRGVFVAGSGTDVGKTVCAGALLRALRQMRMPVQAVKPVQTGIPASAHAVSAQSDAAVYTAAVA
GVASTGRLQPAAMLHCFELPASPHLAAAREGKKLDCMSLRGDILAHWATVPARALLLEGAGGLRVPLNEDEDMLDLMAVL
GLPVFLVGGNYLGCLNHILLSIDALRHSGLELAGLALVPSVDPDAGCPGVDIAAMLADNARILRHRLGRTGSDAPVVELP
RLKNLDEGGWDKLARLLTPVALRMAQAWSEPALAGGQASSEEQNLVRRDRAAVWHPYASALDFPPLNAVRRTWANRIVLA
DGRELVDGMSSWWAAVHGYNNPHLLDALRVQAGRMPHVMFGGLTHEPAVALAERLLGLMPEGLERVFFSDSGSVAVDVAL
KMALQYQYARGETGRTCFLTPRGGYHGDTIGAMSVCDPVTGMHGLFAGMLPRQLFMEQPSCGFDQPFDPASLDNARQMLE
QHGKKIAAVILEPVVQGAGGMWFYHPEYLRGLAQLCRDADTLLIFDEIATGFGRTGKMFAAEWAGISPDILCCGKALTGG
VLTLAATVCNKRVAEGICRDGGVFMHGPTFMANALACAVAGASLDLLSSGRWRQQVGDIERDLRTGLAPCRDMPGVAHVR
VLGAIGVVEMKEPVNTRTLQAFFVDQGVWLRPFNRLIYLMPPYVTPAGDTLRLCAAVEEALRQGAHLS
>Mature_707_residues
TRAVEKCCPDHMCEPLRGVFVAGSGTDVGKTVCAGALLRALRQMRMPVQAVKPVQTGIPASAHAVSAQSDAAVYTAAVAG
VASTGRLQPAAMLHCFELPASPHLAAAREGKKLDCMSLRGDILAHWATVPARALLLEGAGGLRVPLNEDEDMLDLMAVLG
LPVFLVGGNYLGCLNHILLSIDALRHSGLELAGLALVPSVDPDAGCPGVDIAAMLADNARILRHRLGRTGSDAPVVELPR
LKNLDEGGWDKLARLLTPVALRMAQAWSEPALAGGQASSEEQNLVRRDRAAVWHPYASALDFPPLNAVRRTWANRIVLAD
GRELVDGMSSWWAAVHGYNNPHLLDALRVQAGRMPHVMFGGLTHEPAVALAERLLGLMPEGLERVFFSDSGSVAVDVALK
MALQYQYARGETGRTCFLTPRGGYHGDTIGAMSVCDPVTGMHGLFAGMLPRQLFMEQPSCGFDQPFDPASLDNARQMLEQ
HGKKIAAVILEPVVQGAGGMWFYHPEYLRGLAQLCRDADTLLIFDEIATGFGRTGKMFAAEWAGISPDILCCGKALTGGV
LTLAATVCNKRVAEGICRDGGVFMHGPTFMANALACAVAGASLDLLSSGRWRQQVGDIERDLRTGLAPCRDMPGVAHVRV
LGAIGVVEMKEPVNTRTLQAFFVDQGVWLRPFNRLIYLMPPYVTPAGDTLRLCAAVEEALRQGAHLS

Specific function: Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor [H]

COG id: COG0161

COG function: function code H; Adenosylmethionine-8-amino-7-oxononanoate aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=390, Percent_Identity=28.974358974359, Blast_Score=110, Evalue=4e-24,
Organism=Homo sapiens, GI284507298, Length=315, Percent_Identity=30.1587301587302, Blast_Score=94, Evalue=3e-19,
Organism=Escherichia coli, GI1786991, Length=415, Percent_Identity=56.6265060240964, Blast_Score=448, Evalue=1e-127,
Organism=Escherichia coli, GI145693181, Length=296, Percent_Identity=35.8108108108108, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI1789759, Length=331, Percent_Identity=30.8157099697885, Blast_Score=135, Evalue=9e-33,
Organism=Escherichia coli, GI1789016, Length=353, Percent_Identity=29.1784702549575, Blast_Score=125, Evalue=1e-29,
Organism=Escherichia coli, GI1788044, Length=317, Percent_Identity=32.1766561514196, Blast_Score=122, Evalue=9e-29,
Organism=Escherichia coli, GI1787560, Length=337, Percent_Identity=28.7833827893175, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1786349, Length=377, Percent_Identity=28.1167108753316, Blast_Score=96, Evalue=9e-21,
Organism=Escherichia coli, GI1786995, Length=174, Percent_Identity=33.3333333333333, Blast_Score=87, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI25144271, Length=351, Percent_Identity=27.3504273504274, Blast_Score=109, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI25144274, Length=128, Percent_Identity=39.0625, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32564660, Length=339, Percent_Identity=28.023598820059, Blast_Score=93, Evalue=5e-19,
Organism=Saccharomyces cerevisiae, GI6324386, Length=462, Percent_Identity=42.6406926406926, Blast_Score=360, Evalue=1e-100,
Organism=Saccharomyces cerevisiae, GI6323470, Length=412, Percent_Identity=27.6699029126214, Blast_Score=122, Evalue=3e-28,
Organism=Saccharomyces cerevisiae, GI6324432, Length=303, Percent_Identity=28.7128712871287, Blast_Score=116, Evalue=1e-26,
Organism=Drosophila melanogaster, GI21357415, Length=377, Percent_Identity=25.9946949602122, Blast_Score=110, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005814
- InterPro:   IPR005815
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.62 [H]

Molecular weight: Translated: 75734; Mature: 75602

Theoretical pI: Translated: 6.83; Mature: 6.83

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTRAVEKCCPDHMCEPLRGVFVAGSGTDVGKTVCAGALLRALRQMRMPVQAVKPVQTGIP
CCCCHHHCCHHHHCCHHHCEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHCHHHHCCC
ASAHAVSAQSDAAVYTAAVAGVASTGRLQPAAMLHCFELPASPHLAAAREGKKLDCMSLR
CCHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHH
GDILAHWATVPARALLLEGAGGLRVPLNEDEDMLDLMAVLGLPVFLVGGNYLGCLNHILL
HHHHHHHHHHHHHHHEEECCCCEECCCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHH
SIDALRHSGLELAGLALVPSVDPDAGCPGVDIAAMLADNARILRHRLGRTGSDAPVVELP
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCHHHHHHHHCCCCCCCCCEECC
RLKNLDEGGWDKLARLLTPVALRMAQAWSEPALAGGQASSEEQNLVRRDRAAVWHPYASA
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHH
LDFPPLNAVRRTWANRIVLADGRELVDGMSSWWAAVHGYNNPHLLDALRVQAGRMPHVMF
CCCCCHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEE
GGLTHEPAVALAERLLGLMPEGLERVFFSDSGSVAVDVALKMALQYQYARGETGRTCFLT
CCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEE
PRGGYHGDTIGAMSVCDPVTGMHGLFAGMLPRQLFMEQPSCGFDQPFDPASLDNARQMLE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
QHGKKIAAVILEPVVQGAGGMWFYHPEYLRGLAQLCRDADTLLIFDEIATGFGRTGKMFA
HHCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHCCCCCEEEEHHHHHCCCCCCCCHH
AEWAGISPDILCCGKALTGGVLTLAATVCNKRVAEGICRDGGVFMHGPTFMANALACAVA
HHHCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHH
GASLDLLSSGRWRQQVGDIERDLRTGLAPCRDMPGVAHVRVLGAIGVVEMKEPVNTRTLQ
CCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCEEECCCCCHHHEE
AFFVDQGVWLRPFNRLIYLMPPYVTPAGDTLRLCAAVEEALRQGAHLS
EEEECCCCEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TRAVEKCCPDHMCEPLRGVFVAGSGTDVGKTVCAGALLRALRQMRMPVQAVKPVQTGIP
CCCHHHCCHHHHCCHHHCEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHCHHHHCCC
ASAHAVSAQSDAAVYTAAVAGVASTGRLQPAAMLHCFELPASPHLAAAREGKKLDCMSLR
CCHHHCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCCCCCHHHHCCCCCCCHHHHH
GDILAHWATVPARALLLEGAGGLRVPLNEDEDMLDLMAVLGLPVFLVGGNYLGCLNHILL
HHHHHHHHHHHHHHHEEECCCCEECCCCCCHHHHHHHHHHCCCEEEECCCHHHHHHHHHH
SIDALRHSGLELAGLALVPSVDPDAGCPGVDIAAMLADNARILRHRLGRTGSDAPVVELP
HHHHHHHCCCCEEEEEEECCCCCCCCCCCCHHHHHHHCCHHHHHHHHCCCCCCCCCEECC
RLKNLDEGGWDKLARLLTPVALRMAQAWSEPALAGGQASSEEQNLVRRDRAAVWHPYASA
CCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHH
LDFPPLNAVRRTWANRIVLADGRELVDGMSSWWAAVHGYNNPHLLDALRVQAGRMPHVMF
CCCCCHHHHHHHHHCEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCEEEE
GGLTHEPAVALAERLLGLMPEGLERVFFSDSGSVAVDVALKMALQYQYARGETGRTCFLT
CCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCEEHHHHHHHHHHHHHHCCCCCCEEEEE
PRGGYHGDTIGAMSVCDPVTGMHGLFAGMLPRQLFMEQPSCGFDQPFDPASLDNARQMLE
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHH
QHGKKIAAVILEPVVQGAGGMWFYHPEYLRGLAQLCRDADTLLIFDEIATGFGRTGKMFA
HHCHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHCCCCCEEEEHHHHHCCCCCCCCHH
AEWAGISPDILCCGKALTGGVLTLAATVCNKRVAEGICRDGGVFMHGPTFMANALACAVA
HHHCCCCCCCEECCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHH
GASLDLLSSGRWRQQVGDIERDLRTGLAPCRDMPGVAHVRVLGAIGVVEMKEPVNTRTLQ
CCCHHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCEEECCCCCHHHEE
AFFVDQGVWLRPFNRLIYLMPPYVTPAGDTLRLCAAVEEALRQGAHLS
EEEECCCCEECCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]