Click here to switch to the map view.

The map label for this gene is queC [H]

Identifier: 220904355

GI number: 220904355

Start: 1268762

End: 1269538

Strand: Reverse

Name: queC [H]

Synonym: Ddes_1083

Alternate gene names: 220904355

Gene position: 1269538-1268762 (Counterclockwise)

Preceding gene: 220904356

Following gene: 220904354

Centisome position: 44.18

GC content: 58.3

Gene sequence:

>777_bases
ATGAGCCGACAGTCCCCGGGCAGAACCACGTCAAGTCCGCTGGCCGACCAGACAGCCCTGGTCATTTTTTCCGGTGGCCA
GGACTCCGCAACATGTCTTGCGTGGGCTCTGGACCGCTTTGCCCGTGTCCGCACACTGGGTTTTGACTACGGCCAGCGCC
ATGCCGTGGAATTGGCCTGCCGCCAGAACCTCCGTGAAAAACTGGCTACTCTCAACCCGCAGTGGGCCGCCCGCCTGGAT
GCGGATTGCTTGCTTGATATCGGCCTTTTCCGCCAGCTTGCCAATACCGCCCTCACCTCTACCTCGCCCATTGAAGATAA
ACCAGAGGGTCTGCCCAATACCTTTGTTCCGGGCCGCAATCTCATATTTATCCTGCATGCCGCCGCATGGGCCTACGGGC
TTGATATCCGTCATATGGTCCTTGGCGTATGCCAGAGTGACTCCTCGGGCTATCCAGACTGCCGTGACGACAGCATCAAA
GCCATGCAGGTAGCCCTGAATGTCGGCATGGACGCGAATTTTGTACTGCATACGCCCCTCATGTGGCGCAGTAAAAAAGA
TGCCTGGACCCTGGCGGAAGTTCTTGGCGGGGCAAACCTGGTTGACCTGATCGTTGAGGAAAGCCACACCTGTTATGAAG
GGCAGCGCGGACAGCGGCATCCCTGGGGCTACGGCTGCGGGCAATGTCCGGCCTGCCGTCTGCGGGCGGCGGGATATACC
GAATATCTGACCGAAAAGTCCGAAGCAAAGGAGCGGGTATGTCCAAAAAACAGTTAA

Upstream 100 bases:

>100_bases
ACATACGCCCGCGAAACCGTGTGTATTTCGGCAACCTGATGGATGCCTTCATGGCAGGCTACGCTCCTGCGCGGGTGTGT
TCCTTCTGGCCGGTGACGCC

Downstream 100 bases:

>100_bases
GCGCGGCCCAGGGCGTTGAGGTGGCCTGTATTCTTTTCACTCTCAACACGGATCCCGAGGGCATGGTGCGCCTGGCACAC
AGCGCCCTCCTGCCTCCTGC

Product: exsB protein

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC [H]

Number of amino acids: Translated: 258; Mature: 257

Protein sequence:

>258_residues
MSRQSPGRTTSSPLADQTALVIFSGGQDSATCLAWALDRFARVRTLGFDYGQRHAVELACRQNLREKLATLNPQWAARLD
ADCLLDIGLFRQLANTALTSTSPIEDKPEGLPNTFVPGRNLIFILHAAAWAYGLDIRHMVLGVCQSDSSGYPDCRDDSIK
AMQVALNVGMDANFVLHTPLMWRSKKDAWTLAEVLGGANLVDLIVEESHTCYEGQRGQRHPWGYGCGQCPACRLRAAGYT
EYLTEKSEAKERVCPKNS

Sequences:

>Translated_258_residues
MSRQSPGRTTSSPLADQTALVIFSGGQDSATCLAWALDRFARVRTLGFDYGQRHAVELACRQNLREKLATLNPQWAARLD
ADCLLDIGLFRQLANTALTSTSPIEDKPEGLPNTFVPGRNLIFILHAAAWAYGLDIRHMVLGVCQSDSSGYPDCRDDSIK
AMQVALNVGMDANFVLHTPLMWRSKKDAWTLAEVLGGANLVDLIVEESHTCYEGQRGQRHPWGYGCGQCPACRLRAAGYT
EYLTEKSEAKERVCPKNS
>Mature_257_residues
SRQSPGRTTSSPLADQTALVIFSGGQDSATCLAWALDRFARVRTLGFDYGQRHAVELACRQNLREKLATLNPQWAARLDA
DCLLDIGLFRQLANTALTSTSPIEDKPEGLPNTFVPGRNLIFILHAAAWAYGLDIRHMVLGVCQSDSSGYPDCRDDSIKA
MQVALNVGMDANFVLHTPLMWRSKKDAWTLAEVLGGANLVDLIVEESHTCYEGQRGQRHPWGYGCGQCPACRLRAAGYTE
YLTEKSEAKERVCPKNS

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) [H]

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family [H]

Homologues:

Organism=Escherichia coli, GI1786648, Length=234, Percent_Identity=44.4444444444444, Blast_Score=189, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR018317
- InterPro:   IPR014729 [H]

Pfam domain/function: PF06508 ExsB [H]

EC number: NA

Molecular weight: Translated: 28449; Mature: 28317

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRQSPGRTTSSPLADQTALVIFSGGQDSATCLAWALDRFARVRTLGFDYGQRHAVELAC
CCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RQNLREKLATLNPQWAARLDADCLLDIGLFRQLANTALTSTSPIEDKPEGLPNTFVPGRN
HHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
LIFILHAAAWAYGLDIRHMVLGVCQSDSSGYPDCRDDSIKAMQVALNVGMDANFVLHTPL
EEEEEEHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCH
MWRSKKDAWTLAEVLGGANLVDLIVEESHTCYEGQRGQRHPWGYGCGQCPACRLRAAGYT
HHCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHH
EYLTEKSEAKERVCPKNS
HHHHCHHHHHHHCCCCCC
>Mature Secondary Structure 
SRQSPGRTTSSPLADQTALVIFSGGQDSATCLAWALDRFARVRTLGFDYGQRHAVELAC
CCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
RQNLREKLATLNPQWAARLDADCLLDIGLFRQLANTALTSTSPIEDKPEGLPNTFVPGRN
HHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCC
LIFILHAAAWAYGLDIRHMVLGVCQSDSSGYPDCRDDSIKAMQVALNVGMDANFVLHTPL
EEEEEEHHHHHHCCCHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEEEECCH
MWRSKKDAWTLAEVLGGANLVDLIVEESHTCYEGQRGQRHPWGYGCGQCPACRLRAAGYT
HHCCCCCHHHHHHHHCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHCCHH
EYLTEKSEAKERVCPKNS
HHHHCHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA