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The map label for this gene is hflX [C]

Identifier: 218884581

GI number: 218884581

Start: 1187582

End: 1188637

Strand: Direct

Name: hflX [C]

Synonym: DKAM_1270

Alternate gene names: 218884581

Gene position: 1187582-1188637 (Clockwise)

Preceding gene: 218884580

Following gene: 218884582

Centisome position: 86.99

GC content: 44.79

Gene sequence:

>1056_bases
TTGAGGGTTGTCGTGGTAGTACCGAGGAAATATTGGGTTTTCCTCGAGGAGGAGCTGGGACTAGTTAAAACCATTTACAG
TGACATAGTAGAAGTGTTGAAGACGAAGGGTTCCCCATCAGGAACATACCTACCGAGGGAGAAGATCGAGTTTTTACGTG
GCAGCGACTTTGATAAGTTAATAGTGATGGATAGGCTTAAACCAATACAGATAGTTAACCTGATTAAAGAATTAAGGAGG
GATGTGATCGACAGGGTTATGTTGATCCTCGAGATATTCGCTGAACACGCTGGCTCGAAGGAAGCCAAGATGCAGATAGA
GCTTGCTAGGCTGAAATACTATATTCCACTAGTCAAGGAAGCTATAAGATATGCTAAGATAGGCGAGTTACACGGCTTCC
TCGGTGCTGGTAGATATGGGTATGAGAAGTACTATCTAATGCTTAAGAAGAGGGAGGCCAGGGTGAGGAGGGAGTTAGAG
GAGCTTAGGAGGATACGTGGAATAAGGAGAATGCAGAGGCTTAAAGCCGGATTCCCCCATGTCGCGATAGCAGGATATAC
ATGTGCAGGCAAGACAACCCTATTCAATGCGATCACAGGGTTAAGTATGCTGGTTGGACCGGAACCCTTTACAACGCTCT
CCCCTAAATCTCGTAGGATAGTTTATAGGGATGCATCGTTCATCCTAACCGATACCGTTGGCTTCATAAGAGATCTACCG
CCTGAGGTTATTGAAGCGTTTTACGCTACACTTGAGGAGATCACCGCAGCAGATGTCATAGTGAATGTTGTGGATGCTTC
CAAGCCGATTGAGAGGATAAGAATAGAGCTTGAGACAACCAGGGAGATACTCAGTAGGATCGGGGTTCATAGTAAACCCA
TGGTAGTGGCATTGAATAAGATAGACCTGGTGGATGACTATGCTAGTATCGCAAGTGAAGTCAAGGTATTACTGGCTAGT
AATGAGACCCTTATACCCATTTCCTCGGTTAAGAGGATTAATATCGATAGATTAATGGATACAGTATACATGTTAGTTAA
GGGTGGCTACCAGTGA

Upstream 100 bases:

>100_bases
GTAGTCGAGGAAAACGTGTCGTCGAATCATGAGAGCAGCGAGGACTTAACAATAGGCGACCTCATCAGGTTTAAACGGGA
GTAGGGGTGTCCGGGAAGTA

Downstream 100 bases:

>100_bases
AGATATACGTGTTAAGGTATGGTCATAGGCCGGGTAGGGATAAACGGGTCACTACGCATGTAGCTCTTGTATCAAGGGCT
TTTGGGGCCAACGGATTCAT

Product: small GTP-binding protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MRVVVVVPRKYWVFLEEELGLVKTIYSDIVEVLKTKGSPSGTYLPREKIEFLRGSDFDKLIVMDRLKPIQIVNLIKELRR
DVIDRVMLILEIFAEHAGSKEAKMQIELARLKYYIPLVKEAIRYAKIGELHGFLGAGRYGYEKYYLMLKKREARVRRELE
ELRRIRGIRRMQRLKAGFPHVAIAGYTCAGKTTLFNAITGLSMLVGPEPFTTLSPKSRRIVYRDASFILTDTVGFIRDLP
PEVIEAFYATLEEITAADVIVNVVDASKPIERIRIELETTREILSRIGVHSKPMVVALNKIDLVDDYASIASEVKVLLAS
NETLIPISSVKRINIDRLMDTVYMLVKGGYQ

Sequences:

>Translated_351_residues
MRVVVVVPRKYWVFLEEELGLVKTIYSDIVEVLKTKGSPSGTYLPREKIEFLRGSDFDKLIVMDRLKPIQIVNLIKELRR
DVIDRVMLILEIFAEHAGSKEAKMQIELARLKYYIPLVKEAIRYAKIGELHGFLGAGRYGYEKYYLMLKKREARVRRELE
ELRRIRGIRRMQRLKAGFPHVAIAGYTCAGKTTLFNAITGLSMLVGPEPFTTLSPKSRRIVYRDASFILTDTVGFIRDLP
PEVIEAFYATLEEITAADVIVNVVDASKPIERIRIELETTREILSRIGVHSKPMVVALNKIDLVDDYASIASEVKVLLAS
NETLIPISSVKRINIDRLMDTVYMLVKGGYQ
>Mature_351_residues
MRVVVVVPRKYWVFLEEELGLVKTIYSDIVEVLKTKGSPSGTYLPREKIEFLRGSDFDKLIVMDRLKPIQIVNLIKELRR
DVIDRVMLILEIFAEHAGSKEAKMQIELARLKYYIPLVKEAIRYAKIGELHGFLGAGRYGYEKYYLMLKKREARVRRELE
ELRRIRGIRRMQRLKAGFPHVAIAGYTCAGKTTLFNAITGLSMLVGPEPFTTLSPKSRRIVYRDASFILTDTVGFIRDLP
PEVIEAFYATLEEITAADVIVNVVDASKPIERIRIELETTREILSRIGVHSKPMVVALNKIDLVDDYASIASEVKVLLAS
NETLIPISSVKRINIDRLMDTVYMLVKGGYQ

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310124269, Length=209, Percent_Identity=31.1004784688995, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI310124267, Length=209, Percent_Identity=31.1004784688995, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI310124171, Length=209, Percent_Identity=31.1004784688995, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI310124169, Length=209, Percent_Identity=31.1004784688995, Blast_Score=92, Evalue=7e-19,
Organism=Homo sapiens, GI310133116, Length=209, Percent_Identity=30.622009569378, Blast_Score=89, Evalue=5e-18,
Organism=Homo sapiens, GI310133118, Length=188, Percent_Identity=32.4468085106383, Blast_Score=88, Evalue=1e-17,
Organism=Escherichia coli, GI1790615, Length=244, Percent_Identity=37.2950819672131, Blast_Score=149, Evalue=3e-37,
Organism=Caenorhabditis elegans, GI17561038, Length=253, Percent_Identity=29.2490118577075, Blast_Score=93, Evalue=2e-19,
Organism=Drosophila melanogaster, GI24650079, Length=253, Percent_Identity=33.9920948616601, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 40094; Mature: 40094

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVVVVVPRKYWVFLEEELGLVKTIYSDIVEVLKTKGSPSGTYLPREKIEFLRGSDFDKL
CEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCHH
IVMDRLKPIQIVNLIKELRRDVIDRVMLILEIFAEHAGSKEAKMQIELARLKYYIPLVKE
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AIRYAKIGELHGFLGAGRYGYEKYYLMLKKREARVRRELEELRRIRGIRRMQRLKAGFPH
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VAIAGYTCAGKTTLFNAITGLSMLVGPEPFTTLSPKSRRIVYRDASFILTDTVGFIRDLP
EEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCC
PEVIEAFYATLEEITAADVIVNVVDASKPIERIRIELETTREILSRIGVHSKPMVVALNK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECC
IDLVDDYASIASEVKVLLASNETLIPISSVKRINIDRLMDTVYMLVKGGYQ
HHHHHHHHHHHHHHEEHEECCCEEEEHHHHHHCCHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MRVVVVVPRKYWVFLEEELGLVKTIYSDIVEVLKTKGSPSGTYLPREKIEFLRGSDFDKL
CEEEEEECCCEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHCCCCCCHH
IVMDRLKPIQIVNLIKELRRDVIDRVMLILEIFAEHAGSKEAKMQIELARLKYYIPLVKE
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHH
AIRYAKIGELHGFLGAGRYGYEKYYLMLKKREARVRRELEELRRIRGIRRMQRLKAGFPH
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
VAIAGYTCAGKTTLFNAITGLSMLVGPEPFTTLSPKSRRIVYRDASFILTDTVGFIRDLP
EEEEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCCCHHHHHHHHHHCCC
PEVIEAFYATLEEITAADVIVNVVDASKPIERIRIELETTREILSRIGVHSKPMVVALNK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEECC
IDLVDDYASIASEVKVLLASNETLIPISSVKRINIDRLMDTVYMLVKGGYQ
HHHHHHHHHHHHHHEEHEECCCEEEEHHHHHHCCHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]