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The map label for this gene is nrdD [C]

Identifier: 218884429

GI number: 218884429

Start: 1051809

End: 1054355

Strand: Direct

Name: nrdD [C]

Synonym: DKAM_1118

Alternate gene names: 218884429

Gene position: 1051809-1054355 (Clockwise)

Preceding gene: 218884428

Following gene: 218884430

Centisome position: 77.04

GC content: 49.35

Gene sequence:

>2547_bases
TTGTATTTCCTAGTATTTATCTTGAAGCCTTATCGGAGATGCCTTATGCAGTCAAGCAAGGTTGATACTGATATGAGAGA
TCCCTTTATAGAGTTTGTCAAATGGAGTAGTCTCGACGTAAACGAGAACGCTAATAAATACATGGGTCCAGGCAGCTTCT
TCAGCTACCTGCTCGAGGAATACATGAAGCGCGACATACTAGGCTTACTTCCAAGCCACATCCTTAAAGCACATAGGGAT
GGATTAATATATATTCACAAACTACCCCAGAGCATATACATACCCTACTGCACCGGGCATAGTATGGCAAGGCTACTTGA
GAAAGGCTTGAAGACCCCTACAGTCATCTCCCGTCCAGCAAGACACTTCGACACATTCGTAGACCACGTGGCTAACTACC
TGATCACACTCCAGCACTATTTCACAGGGGCGCAGGCTTTCTCCAGCGTCGAGTGGTACGCGGGTCCATTCATAAGGAGC
GATGGATTAGACTACCGAGGGGTAAAGCAGAATATCCAGAGGCTACTCTATAATTTAAACTATCCAACCAGGATAGGTTT
GCAAACCCCCTTCACGAACTTCACGATAATAATGGATGCATCGAGGAAAGCCCTCGAAGGAGACTACGCCGTCTACGATG
GTAAGAAAACCGAGCCCCTTGGGGCATATGAGAAGGAGGCTAAAATCTTTCTCTTAGCCCTTTTCGAGAACTATATGAAT
GGGGACAGCGTAGGGCAACCATTCACATTCCCAATTCCCACCCTAATGACCACATCTAAACTACTCTGGGAGGATCCAGA
GATATATGAAGCGGTATTCGAGACGGCTGCAAAACGCGGAAGCTTCTACTGGTTAAACACTAGGGTAGTAGACCCGGACG
CCAGTTATGCAATGTGCCTGCATAGCGGTGAGAAGATACCCATCAACAACGATGGCGAAGTTCACGAGCTGACGATGGGA
GAGCTGGTGGAGAAGTACGCTGGTGGAGTAGAGGCCGTGGACCCGGATGGGGCGACATGGTATAAGCCGGCTAGGGAGTT
CAAGGTGCTGGCGTTCAACCCCGAAACAGGCGAGGTAAGCTGGAGGCCTGTGAAGAGAATCCTAGTGAAGAAGTCTAGGA
AAGCCGTCAGAGTCCAGCTTAGTAATGGCACGGGCTTTGTGGCCACGCCAGACCACCCAGTACTGGTCTACAGGAGGAAC
CACAGGAGATACGAGCTGAGGAAGGCCAACGACATACCGAAAGACAGTAAGCTACCAGTGTTACAGGCGGAAATCAGTGG
TGAATACGTAGAGCTCGAAGGGGAAGTCGAGCTAGTGGTAGATGAGGAAAGCCCCTCAATCGAGGCTTGGAAACATAGGA
TGAAGACAGGAAGTGTTGTGTGGGTCAGTATTAAGAGCATAGAAGAGGTGGAGCTTGAAAACGATGAACTGTTCGTCGAC
GTGGAGGTAGACGGGCCCCACTACTTCGTCCACAGCGGGGGCGTGATAACCCACAACTGCTGCAGGATTAGTATTCAGAA
GAACGAGCTTCTCTACGCATACAACGGTGGCTTAACGTTCTCTTTAAGCTCGATTAAAAAAGACGTTGAGGAAGCTAGGG
AAGAATATTGGAACAAGCTTGAGAAGCAGAGGTTCGGCGGGCTGTGGGCAATGCCCGATATAACTGGGAGCGTAAATGTT
GTAGATATCAATATTCCGAGGTTGGCTCTAGAGGCTAGAGGCAATGACACCAGATTCTGGGAGCTCTACGATGAGGCCTT
GAAGCTGGTTAGGGAGGCTGTAGACTGGTTTAGAGCTAGGTATGTGAAAATATTGAAAGAACACCCGAATTTCTACTATA
TGATCACAGAATATATGCCTGAATTCCCCTCATCGCACTTCAACACCATAGGATTAATAGGGCTACCCGAGGCAGCCGCC
ATACTGCTGCAAGAGCCGAAGCTCTGGCTAGACGGAAATAGGAGCGATTGGCTCCGAGCAACAGAGTTGATGAGGAAGAT
GGTCGAGCACGCCACCAATACTGCTAGAAGATGGATGCAGGAGTCGGGCACCCCATGGAATGTTGAGGAGGTCCCAGCCG
AGTCAGCCTCACCCAAGATGGCGGCTCTAGACATGAAGCTATACCCTGAACTAGCAGATTACTTACCAGACCCTGATAAC
CCCGTATACTCGACCAGTATAGCCCCATACTATGCCCCTGAAATGGAGCTCCCCGATAGAATCGAGGTTGAGGCAAGAGT
CCAGAAGTACTTCACGGGGGGCGTGATGATGCATATATTTCTAGCCGAGGAACCCGAGCCAGACGCATTGGCGAAGCTGG
CTAAGAGAATCATGGATACCGATATCGTGTACTGGAGCTTCACCCCTGCATTAACATATTGCCCATCATGCGGGAGAACA
TACACCGGGTTATATAAATCATGCCCGAGATGTGGAAACGAGAACATCGAGGTATGGAGCAGGATTATAGGTTACTATAG
GCCAATAAAGAACTGGAACCCCCAGAGGAGGAAGGAGTTCTGGACACGGAATCACTACGTCTTCTAA

Upstream 100 bases:

>100_bases
AGACGCAGATTTACTAATCCCAGTTAAGATCCTAGTCGAGATAATAACTTCGTTATCTACCAGTGGGTTACATCAGCCAA
CTCAATCCTGCTTAAATATC

Downstream 100 bases:

>100_bases
ACACCGACTCGTTTTCTCGATTTTCTCGTCTGGTGGTTTCTCATGCTCATCAAACTGATTGGTAGCGGGTGGAAGAATAC
CAGCCTAGTTGACGTCCACG

Product: anaerobic ribonucleoside triphosphate reductase

Products: ribonucleoside triphosphate; thioredoxin

Alternate protein names: NA

Number of amino acids: Translated: 848; Mature: 848

Protein sequence:

>848_residues
MYFLVFILKPYRRCLMQSSKVDTDMRDPFIEFVKWSSLDVNENANKYMGPGSFFSYLLEEYMKRDILGLLPSHILKAHRD
GLIYIHKLPQSIYIPYCTGHSMARLLEKGLKTPTVISRPARHFDTFVDHVANYLITLQHYFTGAQAFSSVEWYAGPFIRS
DGLDYRGVKQNIQRLLYNLNYPTRIGLQTPFTNFTIIMDASRKALEGDYAVYDGKKTEPLGAYEKEAKIFLLALFENYMN
GDSVGQPFTFPIPTLMTTSKLLWEDPEIYEAVFETAAKRGSFYWLNTRVVDPDASYAMCLHSGEKIPINNDGEVHELTMG
ELVEKYAGGVEAVDPDGATWYKPAREFKVLAFNPETGEVSWRPVKRILVKKSRKAVRVQLSNGTGFVATPDHPVLVYRRN
HRRYELRKANDIPKDSKLPVLQAEISGEYVELEGEVELVVDEESPSIEAWKHRMKTGSVVWVSIKSIEEVELENDELFVD
VEVDGPHYFVHSGGVITHNCCRISIQKNELLYAYNGGLTFSLSSIKKDVEEAREEYWNKLEKQRFGGLWAMPDITGSVNV
VDINIPRLALEARGNDTRFWELYDEALKLVREAVDWFRARYVKILKEHPNFYYMITEYMPEFPSSHFNTIGLIGLPEAAA
ILLQEPKLWLDGNRSDWLRATELMRKMVEHATNTARRWMQESGTPWNVEEVPAESASPKMAALDMKLYPELADYLPDPDN
PVYSTSIAPYYAPEMELPDRIEVEARVQKYFTGGVMMHIFLAEEPEPDALAKLAKRIMDTDIVYWSFTPALTYCPSCGRT
YTGLYKSCPRCGNENIEVWSRIIGYYRPIKNWNPQRRKEFWTRNHYVF

Sequences:

>Translated_848_residues
MYFLVFILKPYRRCLMQSSKVDTDMRDPFIEFVKWSSLDVNENANKYMGPGSFFSYLLEEYMKRDILGLLPSHILKAHRD
GLIYIHKLPQSIYIPYCTGHSMARLLEKGLKTPTVISRPARHFDTFVDHVANYLITLQHYFTGAQAFSSVEWYAGPFIRS
DGLDYRGVKQNIQRLLYNLNYPTRIGLQTPFTNFTIIMDASRKALEGDYAVYDGKKTEPLGAYEKEAKIFLLALFENYMN
GDSVGQPFTFPIPTLMTTSKLLWEDPEIYEAVFETAAKRGSFYWLNTRVVDPDASYAMCLHSGEKIPINNDGEVHELTMG
ELVEKYAGGVEAVDPDGATWYKPAREFKVLAFNPETGEVSWRPVKRILVKKSRKAVRVQLSNGTGFVATPDHPVLVYRRN
HRRYELRKANDIPKDSKLPVLQAEISGEYVELEGEVELVVDEESPSIEAWKHRMKTGSVVWVSIKSIEEVELENDELFVD
VEVDGPHYFVHSGGVITHNCCRISIQKNELLYAYNGGLTFSLSSIKKDVEEAREEYWNKLEKQRFGGLWAMPDITGSVNV
VDINIPRLALEARGNDTRFWELYDEALKLVREAVDWFRARYVKILKEHPNFYYMITEYMPEFPSSHFNTIGLIGLPEAAA
ILLQEPKLWLDGNRSDWLRATELMRKMVEHATNTARRWMQESGTPWNVEEVPAESASPKMAALDMKLYPELADYLPDPDN
PVYSTSIAPYYAPEMELPDRIEVEARVQKYFTGGVMMHIFLAEEPEPDALAKLAKRIMDTDIVYWSFTPALTYCPSCGRT
YTGLYKSCPRCGNENIEVWSRIIGYYRPIKNWNPQRRKEFWTRNHYVF
>Mature_848_residues
MYFLVFILKPYRRCLMQSSKVDTDMRDPFIEFVKWSSLDVNENANKYMGPGSFFSYLLEEYMKRDILGLLPSHILKAHRD
GLIYIHKLPQSIYIPYCTGHSMARLLEKGLKTPTVISRPARHFDTFVDHVANYLITLQHYFTGAQAFSSVEWYAGPFIRS
DGLDYRGVKQNIQRLLYNLNYPTRIGLQTPFTNFTIIMDASRKALEGDYAVYDGKKTEPLGAYEKEAKIFLLALFENYMN
GDSVGQPFTFPIPTLMTTSKLLWEDPEIYEAVFETAAKRGSFYWLNTRVVDPDASYAMCLHSGEKIPINNDGEVHELTMG
ELVEKYAGGVEAVDPDGATWYKPAREFKVLAFNPETGEVSWRPVKRILVKKSRKAVRVQLSNGTGFVATPDHPVLVYRRN
HRRYELRKANDIPKDSKLPVLQAEISGEYVELEGEVELVVDEESPSIEAWKHRMKTGSVVWVSIKSIEEVELENDELFVD
VEVDGPHYFVHSGGVITHNCCRISIQKNELLYAYNGGLTFSLSSIKKDVEEAREEYWNKLEKQRFGGLWAMPDITGSVNV
VDINIPRLALEARGNDTRFWELYDEALKLVREAVDWFRARYVKILKEHPNFYYMITEYMPEFPSSHFNTIGLIGLPEAAA
ILLQEPKLWLDGNRSDWLRATELMRKMVEHATNTARRWMQESGTPWNVEEVPAESASPKMAALDMKLYPELADYLPDPDN
PVYSTSIAPYYAPEMELPDRIEVEARVQKYFTGGVMMHIFLAEEPEPDALAKLAKRIMDTDIVYWSFTPALTYCPSCGRT
YTGLYKSCPRCGNENIEVWSRIIGYYRPIKNWNPQRRKEFWTRNHYVF

Specific function: Unknown

COG id: COG1328

COG function: function code F; Oxygen-sensitive ribonucleoside-triphosphate reductase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 DOD-type homing endonuclease domains [H]

Homologues:

Organism=Escherichia coli, GI1790686, Length=312, Percent_Identity=23.3974358974359, Blast_Score=72, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005144
- InterPro:   IPR003586
- InterPro:   IPR003587
- InterPro:   IPR007869
- InterPro:   IPR006142
- InterPro:   IPR004042
- InterPro:   IPR006141
- InterPro:   IPR012833 [H]

Pfam domain/function: PF03477 ATP-cone; PF05204 Hom_end [H]

EC number: 1.17.4.2

Molecular weight: Translated: 97850; Mature: 97850

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: PS50817 INTEIN_N_TER ; PS50818 INTEIN_C_TER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYFLVFILKPYRRCLMQSSKVDTDMRDPFIEFVKWSSLDVNENANKYMGPGSFFSYLLEE
CEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
YMKRDILGLLPSHILKAHRDGLIYIHKLPQSIYIPYCTGHSMARLLEKGLKTPTVISRPA
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCHHHHHHHHHCCCCCHHHCCCH
RHFDTFVDHVANYLITLQHYFTGAQAFSSVEWYAGPFIRSDGLDYRGVKQNIQRLLYNLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEECCCCCCCHHHHHHHHHHHHCC
YPTRIGLQTPFTNFTIIMDASRKALEGDYAVYDGKKTEPLGAYEKEAKIFLLALFENYMN
CCEEECCCCCCCCEEEEEECCCHHCCCCEEEECCCCCCCCCCCCCCCCEEEEEHHHHHCC
GDSVGQPFTFPIPTLMTTSKLLWEDPEIYEAVFETAAKRGSFYWLNTRVVDPDASYAMCL
CCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEE
HSGEKIPINNDGEVHELTMGELVEKYAGGVEAVDPDGATWYKPAREFKVLAFNPETGEVS
ECCCCCCCCCCCCEEEEHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEEECCCCCCCC
WRPVKRILVKKSRKAVRVQLSNGTGFVATPDHPVLVYRRNHRRYELRKANDIPKDSKLPV
HHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCEEEEECCCCEEEEHHCCCCCCCCCCCE
LQAEISGEYVELEGEVELVVDEESPSIEAWKHRMKTGSVVWVSIKSIEEVELENDELFVD
EEEECCCCEEEECCCEEEEEECCCCCHHHHHHHHCCCCEEEEEECCCEEEEECCCEEEEE
VEVDGPHYFVHSGGVITHNCCRISIQKNELLYAYNGGLTFSLSSIKKDVEEAREEYWNKL
EEECCCEEEEECCCEEEECEEEEEEECCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHH
EKQRFGGLWAMPDITGSVNVVDINIPRLALEARGNDTRFWELYDEALKLVREAVDWFRAR
HHHHHCCEEECCCCCCCEEEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
YVKILKEHPNFYYMITEYMPEFPSSHFNTIGLIGLPEAAAILLQEPKLWLDGNRSDWLRA
HHHHHHHCCCEEEEEEHHCCCCCCCCCCEEEEEECCHHHHHHEECCCEEECCCCCHHHHH
TELMRKMVEHATNTARRWMQESGTPWNVEEVPAESASPKMAALDMKLYPELADYLPDPDN
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEEEHHHHHHHHHHHCCCCCC
PVYSTSIAPYYAPEMELPDRIEVEARVQKYFTGGVMMHIFLAEEPEPDALAKLAKRIMDT
CEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCC
DIVYWSFTPALTYCPSCGRTYTGLYKSCPRCGNENIEVWSRIIGYYRPIKNWNPQRRKEF
CEEEEECCCHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
WTRNHYVF
HCCCCCCC
>Mature Secondary Structure
MYFLVFILKPYRRCLMQSSKVDTDMRDPFIEFVKWSSLDVNENANKYMGPGSFFSYLLEE
CEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHH
YMKRDILGLLPSHILKAHRDGLIYIHKLPQSIYIPYCTGHSMARLLEKGLKTPTVISRPA
HHHHHHHHHHHHHHHHHCCCCEEEEEECCCEEEEEEECCHHHHHHHHHCCCCCHHHCCCH
RHFDTFVDHVANYLITLQHYFTGAQAFSSVEWYAGPFIRSDGLDYRGVKQNIQRLLYNLN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCEEECCCCCCCHHHHHHHHHHHHCC
YPTRIGLQTPFTNFTIIMDASRKALEGDYAVYDGKKTEPLGAYEKEAKIFLLALFENYMN
CCEEECCCCCCCCEEEEEECCCHHCCCCEEEECCCCCCCCCCCCCCCCEEEEEHHHHHCC
GDSVGQPFTFPIPTLMTTSKLLWEDPEIYEAVFETAAKRGSFYWLNTRVVDPDASYAMCL
CCCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHCCCEEEEEEEEECCCCCEEEEE
HSGEKIPINNDGEVHELTMGELVEKYAGGVEAVDPDGATWYKPAREFKVLAFNPETGEVS
ECCCCCCCCCCCCEEEEHHHHHHHHHCCCCEEECCCCCCCCCCCCCEEEEEECCCCCCCC
WRPVKRILVKKSRKAVRVQLSNGTGFVATPDHPVLVYRRNHRRYELRKANDIPKDSKLPV
HHHHHHHHHHCCCCEEEEEECCCCEEEECCCCCEEEEECCCCEEEEHHCCCCCCCCCCCE
LQAEISGEYVELEGEVELVVDEESPSIEAWKHRMKTGSVVWVSIKSIEEVELENDELFVD
EEEECCCCEEEECCCEEEEEECCCCCHHHHHHHHCCCCEEEEEECCCEEEEECCCEEEEE
VEVDGPHYFVHSGGVITHNCCRISIQKNELLYAYNGGLTFSLSSIKKDVEEAREEYWNKL
EEECCCEEEEECCCEEEECEEEEEEECCCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHH
EKQRFGGLWAMPDITGSVNVVDINIPRLALEARGNDTRFWELYDEALKLVREAVDWFRAR
HHHHHCCEEECCCCCCCEEEEEEECCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
YVKILKEHPNFYYMITEYMPEFPSSHFNTIGLIGLPEAAAILLQEPKLWLDGNRSDWLRA
HHHHHHHCCCEEEEEEHHCCCCCCCCCCEEEEEECCHHHHHHEECCCEEECCCCCHHHHH
TELMRKMVEHATNTARRWMQESGTPWNVEEVPAESASPKMAALDMKLYPELADYLPDPDN
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEEEHHHHHHHHHHHCCCCCC
PVYSTSIAPYYAPEMELPDRIEVEARVQKYFTGGVMMHIFLAEEPEPDALAKLAKRIMDT
CEEECCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEECCCCCHHHHHHHHHHHHCC
DIVYWSFTPALTYCPSCGRTYTGLYKSCPRCGNENIEVWSRIIGYYRPIKNWNPQRRKEF
CEEEEECCCHHHHCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCCCCHHHHHHH
WTRNHYVF
HCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: Ca2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 2'-deoxyribonucleoside triphosphate; thioredoxin disulfide; H2O

Specific reaction: 2'-deoxyribonucleoside triphosphate + thioredoxin disulfide + H2O = ribonucleoside triphosphate + thioredoxin

General reaction: Redox reaction [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]