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The map label for this gene is 218884428

Identifier: 218884428

GI number: 218884428

Start: 1051006

End: 1051710

Strand: Direct

Name: 218884428

Synonym: DKAM_1117

Alternate gene names: NA

Gene position: 1051006-1051710 (Clockwise)

Preceding gene: 218884407

Following gene: 218884429

Centisome position: 76.98

GC content: 46.52

Gene sequence:

>705_bases
TTGGAGAGAAAGGTGATTGAGCTGGGGAGGCTTAAGATAATACTCGTGGAAGCAGCATTAGAGACTATACCCCCAAGCAT
TGCATCACACCCAGTAGTGCTTAAAAACGCTGGTAAAAGAGGGAAAAGTCCCCATGAGATACTACTCGATGTAAGCATAC
ATTACCACGCCATGAAGAAACTCCCATTGAAGCATAAGCGGGGTAGGCCGGATATCATACATTTAAGCCTGTTAGAGGCG
TTAGAGAGCCCATTAAATAAAACCGGTAGAATGGAGATATACATACACACGATACAGGGGCACGCTATCTTCATTGATTC
ATCAACCAGGATCCCGAGGAACTACAATAGGTTCACAGGGTTAATGGAGCAGTTATTTAAGGAGGGAGAGGTTCCACCAG
GCTCAGAGAAGCCGTTGCTCTATATCAAGACAATGCCGCTTGACTCGTTAATCAAGGCTATTGGGGCAAAGGGGCTGATA
CTCTTAAGTGAATCCTGCGTCCAGAGTAGCCTCGACAATGTGGTTGGGGAGGCATTGAACAATGGATTCGCCATAGGTAT
AGGTGGATTCCCCCATGGAGACTTCGAGGAGGACACTGTGAAACAGGCAGTCAAGTGTTACTCGATATATAGAGGTCCTC
TTGCAACATGGATCGTGGTGTCGAGGATAATAGCTAGCGCTGAGAGATTACTCGGCATACTTTAG

Upstream 100 bases:

>100_bases
TCACCCGTTCCCTAGCAATCTCCCTTATATATTTTTCCCTATTCAAGAACCAGACCCCGCGTGGTGGAGTTATATAATTA
TATTCCACCACGGTATTAAA

Downstream 100 bases:

>100_bases
ACGCAGATTTACTAATCCCAGTTAAGATCCTAGTCGAGATAATAACTTCGTTATCTACCAGTGGGTTACATCAGCCAACT
CAATCCTGCTTAAATATCTT

Product: ribosome biogenesis protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 234; Mature: 234

Protein sequence:

>234_residues
MERKVIELGRLKIILVEAALETIPPSIASHPVVLKNAGKRGKSPHEILLDVSIHYHAMKKLPLKHKRGRPDIIHLSLLEA
LESPLNKTGRMEIYIHTIQGHAIFIDSSTRIPRNYNRFTGLMEQLFKEGEVPPGSEKPLLYIKTMPLDSLIKAIGAKGLI
LLSESCVQSSLDNVVGEALNNGFAIGIGGFPHGDFEEDTVKQAVKCYSIYRGPLATWIVVSRIIASAERLLGIL

Sequences:

>Translated_234_residues
MERKVIELGRLKIILVEAALETIPPSIASHPVVLKNAGKRGKSPHEILLDVSIHYHAMKKLPLKHKRGRPDIIHLSLLEA
LESPLNKTGRMEIYIHTIQGHAIFIDSSTRIPRNYNRFTGLMEQLFKEGEVPPGSEKPLLYIKTMPLDSLIKAIGAKGLI
LLSESCVQSSLDNVVGEALNNGFAIGIGGFPHGDFEEDTVKQAVKCYSIYRGPLATWIVVSRIIASAERLLGIL
>Mature_234_residues
MERKVIELGRLKIILVEAALETIPPSIASHPVVLKNAGKRGKSPHEILLDVSIHYHAMKKLPLKHKRGRPDIIHLSLLEA
LESPLNKTGRMEIYIHTIQGHAIFIDSSTRIPRNYNRFTGLMEQLFKEGEVPPGSEKPLLYIKTMPLDSLIKAIGAKGLI
LLSESCVQSSLDNVVGEALNNGFAIGIGGFPHGDFEEDTVKQAVKCYSIYRGPLATWIVVSRIIASAERLLGIL

Specific function: Involved in ribosomal biogenesis. It seems to play a role a methylation reaction in pre-rRNA processing [H]

COG id: COG1756

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NEP1 family [H]

Homologues:

Organism=Homo sapiens, GI194328699, Length=227, Percent_Identity=29.9559471365639, Blast_Score=77, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17555712, Length=188, Percent_Identity=23.4042553191489, Blast_Score=68, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323215, Length=228, Percent_Identity=27.1929824561404, Blast_Score=79, Evalue=5e-16,
Organism=Drosophila melanogaster, GI24639698, Length=193, Percent_Identity=28.4974093264249, Blast_Score=79, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005304 [H]

Pfam domain/function: PF03587 EMG1 [H]

EC number: NA

Molecular weight: Translated: 25840; Mature: 25840

Theoretical pI: Translated: 9.56; Mature: 9.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERKVIELGRLKIILVEAALETIPPSIASHPVVLKNAGKRGKSPHEILLDVSIHYHAMKK
CCCCHHHHCCEEEEEEEHHHHHCCCCHHCCCEEEECCCCCCCCCCCEEEEEHHHHHHHHH
LPLKHKRGRPDIIHLSLLEALESPLNKTGRMEIYIHTIQGHAIFIDSSTRIPRNYNRFTG
CCCHHCCCCCCEEHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEECCCCCCCCHHHHHH
LMEQLFKEGEVPPGSEKPLLYIKTMPLDSLIKAIGAKGLILLSESCVQSSLDNVVGEALN
HHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHC
NGFAIGIGGFPHGDFEEDTVKQAVKCYSIYRGPLATWIVVSRIIASAERLLGIL
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MERKVIELGRLKIILVEAALETIPPSIASHPVVLKNAGKRGKSPHEILLDVSIHYHAMKK
CCCCHHHHCCEEEEEEEHHHHHCCCCHHCCCEEEECCCCCCCCCCCEEEEEHHHHHHHHH
LPLKHKRGRPDIIHLSLLEALESPLNKTGRMEIYIHTIQGHAIFIDSSTRIPRNYNRFTG
CCCHHCCCCCCEEHHHHHHHHHHHHCCCCCEEEEEEEECCCEEEEECCCCCCCCHHHHHH
LMEQLFKEGEVPPGSEKPLLYIKTMPLDSLIKAIGAKGLILLSESCVQSSLDNVVGEALN
HHHHHHHCCCCCCCCCCCEEEEEECCHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHC
NGFAIGIGGFPHGDFEEDTVKQAVKCYSIYRGPLATWIVVSRIIASAERLLGIL
CCEEEEECCCCCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA