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The map label for this gene is norM [H]

Identifier: 218884143

GI number: 218884143

Start: 802045

End: 803388

Strand: Reverse

Name: norM [H]

Synonym: DKAM_0832

Alternate gene names: 218884143

Gene position: 803388-802045 (Counterclockwise)

Preceding gene: 218884144

Following gene: 218884142

Centisome position: 58.85

GC content: 45.61

Gene sequence:

>1344_bases
ATGAAGAATTATTTCTCAACGCTCCTAAATGATCCAGAGATAAAGTCCTCTCTAAGAATCTCGTTACCACTGGTATTCGT
GGAGCTGGTGAATAGTCTCTACTCATTGGCTGACACCTTCTTCGTTAAAGATCTTGGTAGTGAAGCGTTAGCCGCAGTGG
GTATTGCAGGCTACTTACTAATGCTATTACAGGTCTTCTTCACATTATTTCAAACACCCTTACTCATACTGGTCTCGCAG
AGTATTGGAGCAGGTTATAGGGATAAAACCAGGCTTATAACCGGTGAGATCCTGGTTGAGGGAAGCATTTGCGTGATTTT
TCTATCCATTATATTCTATATAGTGGCGCCGGTATTCGTCGCCATACAGTCAGGGGTAGCTGGCCTCGCGTTCCAATATA
CACTGGATTATCTCAGGATAAGGGTTGCCTGGTTTGTAATATTCTTTGTTTCAGCGTCATTCGATATTGTTTTCATAGCC
AGCGGGAGGTCAGATATATCATTAATATCAAATATCATTGGATTAGTCTCTAACATTATTCTAGACCCCATAATGATCTA
TGGGCTGGCAGGCTTCCCAAGGCTCGGAGTTGCTGGTGCAGCATGGGCGTCGGTCATCGCTTCATTCTTGACTATACCGA
TCCAGCTATATTACCTAGGGAAACTCCAGTTGCTACCCATGAGGCCGGGCTTATTTATTCTACCGAGGAAAATAATAGAC
CTCGGGTTACCAGCCTTCATAGAGAGGAGCGTTATCTCGCTGGGAAACAATATCTATGCTGGAATAATATCAAGGCTAGG
CAATACGGTTATGGCGGCCCATAATATTGGGCTTAGAATCGAGAGCATAATATACATGCCGGGCTTCGCATTCGCTATGA
CGGCCTCAACAATTGTTGGAAGACATGTGGGCGAGGGGGATTTCAAACGTGCTAAGAGGATAGGGGAGAAGGTGATATAT
ATGGGGGCTTCACTAATGGGGTTGCTGGGTGTCGTAGTCGCCTTATCCAGCTATTATATCACAGCCCCCTTCGTGCCGAC
AAGCGAGATCCGTGAGTTGGCATCACTCTACCTTATTCTAGCAGGGTTCAGTGAGTTTGGCCTGGGATTAGCGATGGTTT
CCAGTGGAGCTATAAGGGGAGCCGGCAACACCAGGTTGCCATTTATCACTAATACTGTTTCCCTACTATTATTCAGGGTC
ATCCCCTCACTAATCCTGGTGAAGTCTCTAGGGGTGCTAGGTCCTTGGATAGCGATGTTTATCGAGGTGTATGCGAGGGG
TATTATGGCTTACACGATATTCAAACGCTATTTCAACCAGCTGGCCAGAAGACTTATTAGCTAA

Upstream 100 bases:

>100_bases
AAGCCATCAGGGAAGCACCGTTATTAAAGCTGCCGAAATACCGTAATGGCGGCGAATACATTGCAGAATATATTATGAGA
ATACTCCGGGGTGCAGGGTA

Downstream 100 bases:

>100_bases
CCTGGAGATAACCGAATAATAGTTAATATAATAGTTAATTAGTGGCGGATCCCTTTGTCTGCAACTATTACCTCACTTAT
ACTGGCAGGGGGTCAGGGTG

Product: MATE efflux family protein

Products: NA

Alternate protein names: Multidrug-efflux transporter [H]

Number of amino acids: Translated: 447; Mature: 447

Protein sequence:

>447_residues
MKNYFSTLLNDPEIKSSLRISLPLVFVELVNSLYSLADTFFVKDLGSEALAAVGIAGYLLMLLQVFFTLFQTPLLILVSQ
SIGAGYRDKTRLITGEILVEGSICVIFLSIIFYIVAPVFVAIQSGVAGLAFQYTLDYLRIRVAWFVIFFVSASFDIVFIA
SGRSDISLISNIIGLVSNIILDPIMIYGLAGFPRLGVAGAAWASVIASFLTIPIQLYYLGKLQLLPMRPGLFILPRKIID
LGLPAFIERSVISLGNNIYAGIISRLGNTVMAAHNIGLRIESIIYMPGFAFAMTASTIVGRHVGEGDFKRAKRIGEKVIY
MGASLMGLLGVVVALSSYYITAPFVPTSEIRELASLYLILAGFSEFGLGLAMVSSGAIRGAGNTRLPFITNTVSLLLFRV
IPSLILVKSLGVLGPWIAMFIEVYARGIMAYTIFKRYFNQLARRLIS

Sequences:

>Translated_447_residues
MKNYFSTLLNDPEIKSSLRISLPLVFVELVNSLYSLADTFFVKDLGSEALAAVGIAGYLLMLLQVFFTLFQTPLLILVSQ
SIGAGYRDKTRLITGEILVEGSICVIFLSIIFYIVAPVFVAIQSGVAGLAFQYTLDYLRIRVAWFVIFFVSASFDIVFIA
SGRSDISLISNIIGLVSNIILDPIMIYGLAGFPRLGVAGAAWASVIASFLTIPIQLYYLGKLQLLPMRPGLFILPRKIID
LGLPAFIERSVISLGNNIYAGIISRLGNTVMAAHNIGLRIESIIYMPGFAFAMTASTIVGRHVGEGDFKRAKRIGEKVIY
MGASLMGLLGVVVALSSYYITAPFVPTSEIRELASLYLILAGFSEFGLGLAMVSSGAIRGAGNTRLPFITNTVSLLLFRV
IPSLILVKSLGVLGPWIAMFIEVYARGIMAYTIFKRYFNQLARRLIS
>Mature_447_residues
MKNYFSTLLNDPEIKSSLRISLPLVFVELVNSLYSLADTFFVKDLGSEALAAVGIAGYLLMLLQVFFTLFQTPLLILVSQ
SIGAGYRDKTRLITGEILVEGSICVIFLSIIFYIVAPVFVAIQSGVAGLAFQYTLDYLRIRVAWFVIFFVSASFDIVFIA
SGRSDISLISNIIGLVSNIILDPIMIYGLAGFPRLGVAGAAWASVIASFLTIPIQLYYLGKLQLLPMRPGLFILPRKIID
LGLPAFIERSVISLGNNIYAGIISRLGNTVMAAHNIGLRIESIIYMPGFAFAMTASTIVGRHVGEGDFKRAKRIGEKVIY
MGASLMGLLGVVVALSSYYITAPFVPTSEIRELASLYLILAGFSEFGLGLAMVSSGAIRGAGNTRLPFITNTVSLLLFRV
IPSLILVKSLGVLGPWIAMFIEVYARGIMAYTIFKRYFNQLARRLIS

Specific function: Multidrug efflux pump [H]

COG id: COG0534

COG function: function code V; Na+-driven multidrug efflux pump

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family [H]

Homologues:

Organism=Escherichia coli, GI226510954, Length=435, Percent_Identity=22.7586206896552, Blast_Score=90, Evalue=3e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002528 [H]

Pfam domain/function: PF01554 MatE [H]

EC number: NA

Molecular weight: Translated: 48803; Mature: 48803

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNYFSTLLNDPEIKSSLRISLPLVFVELVNSLYSLADTFFVKDLGSEALAAVGIAGYLL
CCCHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
MLLQVFFTLFQTPLLILVSQSIGAGYRDKTRLITGEILVEGSICVIFLSIIFYIVAPVFV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHEEECCCHHHHHHHHHHHHHHHHHH
AIQSGVAGLAFQYTLDYLRIRVAWFVIFFVSASFDIVFIASGRSDISLISNIIGLVSNII
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHH
LDPIMIYGLAGFPRLGVAGAAWASVIASFLTIPIQLYYLGKLQLLPMRPGLFILPRKIID
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCEEEEECCCCCEEHHHHHHH
LGLPAFIERSVISLGNNIYAGIISRLGNTVMAAHNIGLRIESIIYMPGFAFAMTASTIVG
CCCHHHHHHHHHHHCCHHHHHHHHHHCCCEEHHHCCCCEEEHEEECCCHHHHHHHHHHHH
RHVGEGDFKRAKRIGEKVIYMGASLMGLLGVVVALSSYYITAPFVPTSEIRELASLYLIL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHH
AGFSEFGLGLAMVSSGAIRGAGNTRLPFITNTVSLLLFRVIPSLILVKSLGVLGPWIAMF
HHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEVYARGIMAYTIFKRYFNQLARRLIS
HHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKNYFSTLLNDPEIKSSLRISLPLVFVELVNSLYSLADTFFVKDLGSEALAAVGIAGYLL
CCCHHHHHCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
MLLQVFFTLFQTPLLILVSQSIGAGYRDKTRLITGEILVEGSICVIFLSIIFYIVAPVFV
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEHEEECCCHHHHHHHHHHHHHHHHHH
AIQSGVAGLAFQYTLDYLRIRVAWFVIFFVSASFDIVFIASGRSDISLISNIIGLVSNII
HHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHHHHHHHHHHH
LDPIMIYGLAGFPRLGVAGAAWASVIASFLTIPIQLYYLGKLQLLPMRPGLFILPRKIID
HHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHEEEECCEEEEECCCCCEEHHHHHHH
LGLPAFIERSVISLGNNIYAGIISRLGNTVMAAHNIGLRIESIIYMPGFAFAMTASTIVG
CCCHHHHHHHHHHHCCHHHHHHHHHHCCCEEHHHCCCCEEEHEEECCCHHHHHHHHHHHH
RHVGEGDFKRAKRIGEKVIYMGASLMGLLGVVVALSSYYITAPFVPTSEIRELASLYLIL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHH
AGFSEFGLGLAMVSSGAIRGAGNTRLPFITNTVSLLLFRVIPSLILVKSLGVLGPWIAMF
HHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IEVYARGIMAYTIFKRYFNQLARRLIS
HHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]