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The map label for this gene is pdxS

Identifier: 218883793

GI number: 218883793

Start: 449309

End: 450316

Strand: Reverse

Name: pdxS

Synonym: DKAM_0482

Alternate gene names: 218883793

Gene position: 450316-449309 (Counterclockwise)

Preceding gene: 218883796

Following gene: 218883792

Centisome position: 32.98

GC content: 49.5

Gene sequence:

>1008_bases
TTGAAGCTTGTTGACGCCTACGTGTTCCTCGAGGAGCTAGGAAGCCTTCTCTACAAGCTCTTAGAGCAAAGGGATAAACT
CAGGGAGGAGGGATACCCTGTTCCAGGGAGAGAGGTAGCAACACCCCTGGTGAAATACGGGTTTGTATCTATGCTTAAAG
GCGGGGTCATCATGGATGTGACTAATCCCGAGCAGGCAATCATAGCTGAGGAGGCAGGTGCTGTAGGGGTGATGGTGCTT
GATAAATTACCCTACGATGTCAGAATGGCTGGAGGTGTCGCGAGAACTGCTGATGTAAAGGTTATAGAGGAGGTAATGAG
CTCTATAACTATACCTGTCTCAGCGAAATGTAGGATAGGGCATGAATTTGAGGCCAGGGTTCTAGAGGAAGTTGGAGTCG
ACCTAATAGATGAGAGTGAAGTGTTGACGCCTGTCGATGAGAAAGCCCATATTAATAAATGGTTGTTCAAGACGCCATTT
GTTAATGGTGCTAGAAGCCTCCCAGAGGCGTTGAGAAGAATCTATGAGGGAGCATCAATGATCAGAACCAAGGGGGAGCC
GGGTACTGGTAACGTAGCTGAGGCCGTTAAACACATAAAGATCGTAAACAGGGATATCTACATGCTCAACGGCTACTATA
GGAACGGAGATGTAGAGGCGATATGGGTTTACTCGAAGGAGAACCGAGTTCCCTACGAGCTTGCTCTTCTAACAGCCAGA
CTAGGGAGACTACCTGTCGTGAACTTTGCAGCTGGAGGGATAGCGACGCCTGCAGATGCAGCCTTAATGATGTGGCTTGG
TGCCGATGGAGTCTTCGTTGGCTCAGGCATATTCAAGAGTAATGATCCAGAGGCCAGGGCCCGGGGGATAGTATTAGCAA
CAACTTACTGGGATGACCCGGAGACGGTGCTTGAGGCGCAGAAAATGGTGTCTGAGAAAGCTTCAATGCTCGGGATAGAT
ATCAGGAGGCTTAAACCCGAGGAGTTGATGCAGGAGCGAGGTGTGTAG

Upstream 100 bases:

>100_bases
TATAAACCTATACCTATATAAGACCTGAACCCTTATCCATGGGAACGTTCAACAATGTTTATCCTATAATACAATGCATT
AATACATCTGGTGACCCCTA

Downstream 100 bases:

>100_bases
TCATGATTAAAATAGGCGTCTTAGCTCTGCAGGGAGACTACCTTGAGCATTACCAGGTGCTTAAATCGCTTGGAGGAGTT
GAACCAGTGATCGTTAAGCA

Product: pyridoxal biosynthesis lyase PdxS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKLVDAYVFLEELGSLLYKLLEQRDKLREEGYPVPGREVATPLVKYGFVSMLKGGVIMDVTNPEQAIIAEEAGAVGVMVL
DKLPYDVRMAGGVARTADVKVIEEVMSSITIPVSAKCRIGHEFEARVLEEVGVDLIDESEVLTPVDEKAHINKWLFKTPF
VNGARSLPEALRRIYEGASMIRTKGEPGTGNVAEAVKHIKIVNRDIYMLNGYYRNGDVEAIWVYSKENRVPYELALLTAR
LGRLPVVNFAAGGIATPADAALMMWLGADGVFVGSGIFKSNDPEARARGIVLATTYWDDPETVLEAQKMVSEKASMLGID
IRRLKPEELMQERGV

Sequences:

>Translated_335_residues
MKLVDAYVFLEELGSLLYKLLEQRDKLREEGYPVPGREVATPLVKYGFVSMLKGGVIMDVTNPEQAIIAEEAGAVGVMVL
DKLPYDVRMAGGVARTADVKVIEEVMSSITIPVSAKCRIGHEFEARVLEEVGVDLIDESEVLTPVDEKAHINKWLFKTPF
VNGARSLPEALRRIYEGASMIRTKGEPGTGNVAEAVKHIKIVNRDIYMLNGYYRNGDVEAIWVYSKENRVPYELALLTAR
LGRLPVVNFAAGGIATPADAALMMWLGADGVFVGSGIFKSNDPEARARGIVLATTYWDDPETVLEAQKMVSEKASMLGID
IRRLKPEELMQERGV
>Mature_335_residues
MKLVDAYVFLEELGSLLYKLLEQRDKLREEGYPVPGREVATPLVKYGFVSMLKGGVIMDVTNPEQAIIAEEAGAVGVMVL
DKLPYDVRMAGGVARTADVKVIEEVMSSITIPVSAKCRIGHEFEARVLEEVGVDLIDESEVLTPVDEKAHINKWLFKTPF
VNGARSLPEALRRIYEGASMIRTKGEPGTGNVAEAVKHIKIVNRDIYMLNGYYRNGDVEAIWVYSKENRVPYELALLTAR
LGRLPVVNFAAGGIATPADAALMMWLGADGVFVGSGIFKSNDPEARARGIVLATTYWDDPETVLEAQKMVSEKASMLGID
IRRLKPEELMQERGV

Specific function: Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring

COG id: COG0214

COG function: function code H; Pyridoxine biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxS/SNZ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6321049, Length=282, Percent_Identity=56.3829787234042, Blast_Score=297, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6323996, Length=263, Percent_Identity=58.93536121673, Blast_Score=296, Evalue=2e-81,
Organism=Saccharomyces cerevisiae, GI6323743, Length=269, Percent_Identity=55.0185873605948, Blast_Score=287, Evalue=1e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXS_DESK1 (B8D3X7)

Other databases:

- EMBL:   CP001140
- RefSeq:   YP_002428175.1
- GeneID:   7170712
- GenomeReviews:   CP001140_GR
- KEGG:   dka:DKAM_0482
- HOGENOM:   HBG292342
- OMA:   ARMSDPD
- ProtClustDB:   PRK04180
- HAMAP:   MF_01824
- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR001852
- Gene3D:   G3DSA:3.20.20.70
- PIRSF:   PIRSF029271

Pfam domain/function: PF01680 SOR_SNZ; SSF51366 RibP_bind_barrel

EC number: NA

Molecular weight: Translated: 36944; Mature: 36944

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: PS01235 PDXS_SNZ_1; PS51129 PDXS_SNZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLVDAYVFLEELGSLLYKLLEQRDKLREEGYPVPGREVATPLVKYGFVSMLKGGVIMDV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEE
TNPEQAIIAEEAGAVGVMVLDKLPYDVRMAGGVARTADVKVIEEVMSSITIPVSAKCRIG
CCCCHHEEHHCCCCEEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEECC
HEFEARVLEEVGVDLIDESEVLTPVDEKAHINKWLFKTPFVNGARSLPEALRRIYEGASM
CHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHH
IRTKGEPGTGNVAEAVKHIKIVNRDIYMLNGYYRNGDVEAIWVYSKENRVPYELALLTAR
EEECCCCCCCHHHHHHHHHHHHCCCEEEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHH
LGRLPVVNFAAGGIATPADAALMMWLGADGVFVGSGIFKSNDPEARARGIVLATTYWDDP
HCCCCEEEECCCCCCCCCHHHEEEEECCCCEEEECCCCCCCCCHHHHCEEEEEEEECCCH
ETVLEAQKMVSEKASMLGIDIRRLKPEELMQERGV
HHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHCCC
>Mature Secondary Structure
MKLVDAYVFLEELGSLLYKLLEQRDKLREEGYPVPGREVATPLVKYGFVSMLKGGVIMDV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCEEEEE
TNPEQAIIAEEAGAVGVMVLDKLPYDVRMAGGVARTADVKVIEEVMSSITIPVSAKCRIG
CCCCHHEEHHCCCCEEEEEEECCCCCEEECCCCCCHHHHHHHHHHHHHCCCCCCCCEECC
HEFEARVLEEVGVDLIDESEVLTPVDEKAHINKWLFKTPFVNGARSLPEALRRIYEGASM
CHHHHHHHHHCCCCEECCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCHH
IRTKGEPGTGNVAEAVKHIKIVNRDIYMLNGYYRNGDVEAIWVYSKENRVPYELALLTAR
EEECCCCCCCHHHHHHHHHHHHCCCEEEEEEEEECCCEEEEEEEECCCCCCHHHHHHHHH
LGRLPVVNFAAGGIATPADAALMMWLGADGVFVGSGIFKSNDPEARARGIVLATTYWDDP
HCCCCEEEECCCCCCCCCHHHEEEEECCCCEEEECCCCCCCCCHHHHCEEEEEEEECCCH
ETVLEAQKMVSEKASMLGIDIRRLKPEELMQERGV
HHHHHHHHHHHHHHHHHCCHHHHCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA