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The map label for this gene is dppB [H]

Identifier: 218883598

GI number: 218883598

Start: 267624

End: 268682

Strand: Direct

Name: dppB [H]

Synonym: DKAM_0287

Alternate gene names: 218883598

Gene position: 267624-268682 (Clockwise)

Preceding gene: 218883597

Following gene: 218883599

Centisome position: 19.6

GC content: 44.57

Gene sequence:

>1059_bases
ATGGGTCTGGGAAGATTTCTAGCCAGAAGAATAGCTACCTTCATACCCACGATAATAGGAGTATTATTCATAACCTACCT
TATAGCATACGCCATACCAGCGGATCCTGTTAGGGCCTGGGTCGGAGAGAAATTAATGAACAGGGAGGCCCTTGAAGAAA
TACGCGCGAAATACAAGTTTGATGCACCATGGTATGAGCAATTCGCGTTCTTAGTCACCAGTCTTCTAACAGGTAACCTT
GAAGACCCTATACAACACAGGAACATCTTTGATGAGTTATTCTACAGATTCCCTATAACGGTTGAGGTAGCTATAATGGG
TTTTATCTTCACGGCTATTATAGGCATACCACTAGGCTTCATAGCGGCTCTAAAAAAGGATTCAATAGTAGACTTCTTTG
TTAGGATTTTCGCACTGGTTGGGAGTTCTCTACCAGCATTCGTCTTATACTACTTCCTCATCCTCTTCTTGTTCACGTAC
ATGCATACCACGGTTCTAGCTGGAATGCCCTTCCCCTCACAGACATGTATAGCGTCTATTTCAAGCCTACCTAGTAAAAT
ACCGGTGATAGGGCACATTGTATCGGCTATTGGAAGCGTCCCAATGTTCGGTGCAATGATGTGTGGTGAATGGAGTGTTG
TAGCCGATACCTTCAGGAGGCTTTACCTACCTGGATTAGCACTTGGGTTACTGGATGGTGGATTAATAGCGAGGATAGTT
AGAAACAGCCTGCTCGATAGTCTCAGCCAGGAGTATATTCAATACGCTAAGGCGAGAGGCCTTAGGAAGAGGAGGATATG
GATGCATGCATTAAAGAACGCCTCCATACCAGTTGTAACAGTGCTGGGGACGCTTTTCGGCGGCTTACTCTCAGGCGCGA
TAGTTGCTGAGACAGTGTTCAATATACCGGGTCTCGGTAGATACATCTATAATGCTATAACAAGGCTTAACTTCCCAGCA
ATAATTGGTGGTACCTTCCTGGTAGCCATAGTATATGTAACGGTGAACCTAATAGTTGACATAATCTATGCGGTCCTCGA
CCCGAGGATAAGATATTAA

Upstream 100 bases:

>100_bases
GAACGCGACAGTATGGTATGAACTCTACGGCTTCAAACCATAGGTTACCTGATATTTTTTAAAGCCTCATCCTCGTTTCT
ACCCTATAAGAGGGAGATAA

Downstream 100 bases:

>100_bases
GGGGTGGTGTTAATGGAGGCAATATATAAACTACTCGTTAAGATAATAGATAGCTATGCATCGCTGAGAGATAAGATCAA
TAAGGGTTGGAAGGAGAAGA

Product: binding-protein-dependent transport systems inner membrane component

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 352; Mature: 351

Protein sequence:

>352_residues
MGLGRFLARRIATFIPTIIGVLFITYLIAYAIPADPVRAWVGEKLMNREALEEIRAKYKFDAPWYEQFAFLVTSLLTGNL
EDPIQHRNIFDELFYRFPITVEVAIMGFIFTAIIGIPLGFIAALKKDSIVDFFVRIFALVGSSLPAFVLYYFLILFLFTY
MHTTVLAGMPFPSQTCIASISSLPSKIPVIGHIVSAIGSVPMFGAMMCGEWSVVADTFRRLYLPGLALGLLDGGLIARIV
RNSLLDSLSQEYIQYAKARGLRKRRIWMHALKNASIPVVTVLGTLFGGLLSGAIVAETVFNIPGLGRYIYNAITRLNFPA
IIGGTFLVAIVYVTVNLIVDIIYAVLDPRIRY

Sequences:

>Translated_352_residues
MGLGRFLARRIATFIPTIIGVLFITYLIAYAIPADPVRAWVGEKLMNREALEEIRAKYKFDAPWYEQFAFLVTSLLTGNL
EDPIQHRNIFDELFYRFPITVEVAIMGFIFTAIIGIPLGFIAALKKDSIVDFFVRIFALVGSSLPAFVLYYFLILFLFTY
MHTTVLAGMPFPSQTCIASISSLPSKIPVIGHIVSAIGSVPMFGAMMCGEWSVVADTFRRLYLPGLALGLLDGGLIARIV
RNSLLDSLSQEYIQYAKARGLRKRRIWMHALKNASIPVVTVLGTLFGGLLSGAIVAETVFNIPGLGRYIYNAITRLNFPA
IIGGTFLVAIVYVTVNLIVDIIYAVLDPRIRY
>Mature_351_residues
GLGRFLARRIATFIPTIIGVLFITYLIAYAIPADPVRAWVGEKLMNREALEEIRAKYKFDAPWYEQFAFLVTSLLTGNLE
DPIQHRNIFDELFYRFPITVEVAIMGFIFTAIIGIPLGFIAALKKDSIVDFFVRIFALVGSSLPAFVLYYFLILFLFTYM
HTTVLAGMPFPSQTCIASISSLPSKIPVIGHIVSAIGSVPMFGAMMCGEWSVVADTFRRLYLPGLALGLLDGGLIARIVR
NSLLDSLSQEYIQYAKARGLRKRRIWMHALKNASIPVVTVLGTLFGGLLSGAIVAETVFNIPGLGRYIYNAITRLNFPAI
IGGTFLVAIVYVTVNLIVDIIYAVLDPRIRY

Specific function: Part of the binding-protein-dependent transport system for dipeptides; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0601

COG function: function code EP; ABC-type dipeptide/oligopeptide/nickel transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789965, Length=350, Percent_Identity=34.2857142857143, Blast_Score=211, Evalue=6e-56,
Organism=Escherichia coli, GI1787053, Length=350, Percent_Identity=29.4285714285714, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1787761, Length=346, Percent_Identity=35.2601156069364, Blast_Score=158, Evalue=5e-40,
Organism=Escherichia coli, GI1787497, Length=351, Percent_Identity=27.9202279202279, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1789888, Length=353, Percent_Identity=27.4787535410765, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI1787550, Length=277, Percent_Identity=29.9638989169675, Blast_Score=112, Evalue=3e-26,
Organism=Escherichia coli, GI1788504, Length=390, Percent_Identity=21.7948717948718, Blast_Score=100, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 39139; Mature: 39008

Theoretical pI: Translated: 9.69; Mature: 9.69

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GLGRFLARRIATFIPTIIGVLFITYLIAYAIPADPVRAWVGEKLMNREALEEIRAKYKF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCC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CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]