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The map label for this gene is mcpA [H]

Identifier: 218532676

GI number: 218532676

Start: 5080921

End: 5082612

Strand: Reverse

Name: mcpA [H]

Synonym: Mchl_4791

Alternate gene names: 218532676

Gene position: 5082612-5080921 (Counterclockwise)

Preceding gene: 218532677

Following gene: 218532675

Centisome position: 87.97

GC content: 60.34

Gene sequence:

>1692_bases
ATGCGCTTCCTGAACAACCTTCGGCTAACACTTAAACTGGCGATTCCGGCGTTGGTCCTGATCGCTGTGTCGGTAGGCAT
GGTCCTGCTAGCGCGAGCCAGTCTCAGCACACTTGATCAGAACACGCACGAAATTGTTGAGGTCAGTGCAGCACGTACCA
TAAGAATTCAGCAGCTTGCCTTCGCACTGGACGAAATCACGATCCGCGACAAAAACATTATCATCGAGACCGATCCGAAT
GTGCTTGCAAAGCAGTTCAATCAGTTCAAAGAGGACAAGCAGAAGGCACTCGCCACAGCCGATGAGCTGATTGCGCTGTC
CAGCTCGCCCGAGCGCCGAGTTGTCAATGAGGAGATCAAGCGCCTGCTTGTTGACTACCTTGCATCTGCCGAAAGCGGCA
TCGGCTATGGTATGAAGGGCGACAAGGGCATGGCTGCCAAAATCTCGGGCAGCACAAGCCGTGAGGTTCGGCTGAAGCTG
ATCGCCGAGGTCAATAAGCGTATTGCGGCCAACCTGCAGGAGCTAAAAGCTGCCAAGGAGCGCGCCTCCGAGGTCGCCGC
ATCAGCCACTGCGACTCTTACTGCTGTAGCAGCAGCAGGCCTCATTGCGGCTACTGCGCTTCTTGCGGCCATTGCGACCT
TCGGTGTCGCTCGTCCTCTTAATGCTATGACCACGGCTATGGGGCGTTTGGCTTCCGGTGACCTGGACATCGCCGTGACT
GGGACTAACCGCCGGGATGAAGTCGGATCGCTGGCACGCTCGCTTCAGGTGTTCAAGGACAATGCTATTGAGGCTCGTCA
GGTGGCTGCCGCTCAGGAGGTGGAGAACCAAGCCAAGATGCGCCGCGCCAACCTATTGGACGACCTTACCAAAACGTTCG
AGCGCAGCGTATCCCTGCTCACTCAGGGGCTTGCCGGAGCGGCCACCGAGATGGAGGCAACGGCCCGTGCGATGACCGCG
ACCGCCGACGAGACGACGCATCAGAGTGTCTCAGTGGCCGGCGCGGCTCAGCAGACTTCTGCCAACGTGCAGACCGTCGC
AGCGGCAAGCGAGGAGATGGCTGCGTCGGTAGCGGAGATCGTTCAGCAAGTGAGCCAGTCGGCGCGTATCGCCGATCGCG
CCGTCGAAACAGCTCGCCGGACAGACGCCACGGTGCAGAGGCTTGCTGGCACGGCCGAGCGCATCAGCACCGCAGTGTCA
CTGATCTCGGATATCGCGAGCCAAACCAATCTGTTGGCGCTCAATGCCACGATCGAAGCAGCCCGTGCGGGTGAGGCTGG
ACGCGGCTTCGCGGTTGTTGCAGCCGAGGTCAAGGAACTGGCGGGCCAGACCGGCCGCGCCACGAGTGAGATCGGTGAGC
GGATTGCCGAGATCCAGGCTGCCACGCAGGAGGCGGTCACCGATATTCAGCAGATTGGCCGCGTGATCGGCGAAATGTCC
ACTTACGCAGCAAGCATCGCGGCGGCGATGGAGGAGCAGGGCGCAGCCACTCAAGAAATCACGCGCAACGTACAGCAGGC
TGCACAAGGTACGGAGCAGGTGACTCACAACATCGGTTCAGTGCAGGCAGGCGCTGGCCAGACAAGCGCTGCAGCTTCAC
AGGTGCTGAGCGCGGCGCAGGAACTGGCACGGCACTCGGAAGGCCTCACTCATGAGGTCTCCACCTTCCTGACAGGTGTG
AAGGCGGCGTAA

Upstream 100 bases:

>100_bases
AAAAATTTAAGCTTTCGGCAAGGTTGAGACCTGAAAAGAGGAGCTACGGCTGCGATGGGACCGCAGCACAACATAAGTTA
GTTCCCATGCTGTGTGCCAG

Downstream 100 bases:

>100_bases
AGAACACCACACTCACGCATCTGGAGCCCGTCCGGCAGCCGCCGCGGCGGGCTCTTTTGCATGGGCTACAGAACAGTGCG
CTTGAAGCAAGCCTCACCTT

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 563; Mature: 563

Protein sequence:

>563_residues
MRFLNNLRLTLKLAIPALVLIAVSVGMVLLARASLSTLDQNTHEIVEVSAARTIRIQQLAFALDEITIRDKNIIIETDPN
VLAKQFNQFKEDKQKALATADELIALSSSPERRVVNEEIKRLLVDYLASAESGIGYGMKGDKGMAAKISGSTSREVRLKL
IAEVNKRIAANLQELKAAKERASEVAASATATLTAVAAAGLIAATALLAAIATFGVARPLNAMTTAMGRLASGDLDIAVT
GTNRRDEVGSLARSLQVFKDNAIEARQVAAAQEVENQAKMRRANLLDDLTKTFERSVSLLTQGLAGAATEMEATARAMTA
TADETTHQSVSVAGAAQQTSANVQTVAAASEEMAASVAEIVQQVSQSARIADRAVETARRTDATVQRLAGTAERISTAVS
LISDIASQTNLLALNATIEAARAGEAGRGFAVVAAEVKELAGQTGRATSEIGERIAEIQAATQEAVTDIQQIGRVIGEMS
TYAASIAAAMEEQGAATQEITRNVQQAAQGTEQVTHNIGSVQAGAGQTSAAASQVLSAAQELARHSEGLTHEVSTFLTGV
KAA

Sequences:

>Translated_563_residues
MRFLNNLRLTLKLAIPALVLIAVSVGMVLLARASLSTLDQNTHEIVEVSAARTIRIQQLAFALDEITIRDKNIIIETDPN
VLAKQFNQFKEDKQKALATADELIALSSSPERRVVNEEIKRLLVDYLASAESGIGYGMKGDKGMAAKISGSTSREVRLKL
IAEVNKRIAANLQELKAAKERASEVAASATATLTAVAAAGLIAATALLAAIATFGVARPLNAMTTAMGRLASGDLDIAVT
GTNRRDEVGSLARSLQVFKDNAIEARQVAAAQEVENQAKMRRANLLDDLTKTFERSVSLLTQGLAGAATEMEATARAMTA
TADETTHQSVSVAGAAQQTSANVQTVAAASEEMAASVAEIVQQVSQSARIADRAVETARRTDATVQRLAGTAERISTAVS
LISDIASQTNLLALNATIEAARAGEAGRGFAVVAAEVKELAGQTGRATSEIGERIAEIQAATQEAVTDIQQIGRVIGEMS
TYAASIAAAMEEQGAATQEITRNVQQAAQGTEQVTHNIGSVQAGAGQTSAAASQVLSAAQELARHSEGLTHEVSTFLTGV
KAA
>Mature_563_residues
MRFLNNLRLTLKLAIPALVLIAVSVGMVLLARASLSTLDQNTHEIVEVSAARTIRIQQLAFALDEITIRDKNIIIETDPN
VLAKQFNQFKEDKQKALATADELIALSSSPERRVVNEEIKRLLVDYLASAESGIGYGMKGDKGMAAKISGSTSREVRLKL
IAEVNKRIAANLQELKAAKERASEVAASATATLTAVAAAGLIAATALLAAIATFGVARPLNAMTTAMGRLASGDLDIAVT
GTNRRDEVGSLARSLQVFKDNAIEARQVAAAQEVENQAKMRRANLLDDLTKTFERSVSLLTQGLAGAATEMEATARAMTA
TADETTHQSVSVAGAAQQTSANVQTVAAASEEMAASVAEIVQQVSQSARIADRAVETARRTDATVQRLAGTAERISTAVS
LISDIASQTNLLALNATIEAARAGEAGRGFAVVAAEVKELAGQTGRATSEIGERIAEIQAATQEAVTDIQQIGRVIGEMS
TYAASIAAAMEEQGAATQEITRNVQQAAQGTEQVTHNIGSVQAGAGQTSAAASQVLSAAQELARHSEGLTHEVSTFLTGV
KAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=319, Percent_Identity=28.5266457680251, Blast_Score=92, Evalue=8e-20,
Organism=Escherichia coli, GI1789453, Length=214, Percent_Identity=35.5140186915888, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788194, Length=248, Percent_Identity=30.6451612903226, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788195, Length=221, Percent_Identity=29.8642533936652, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787690, Length=310, Percent_Identity=28.3870967741935, Blast_Score=82, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58892; Mature: 58892

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2 ; PS50192 T_SNARE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFLNNLRLTLKLAIPALVLIAVSVGMVLLARASLSTLDQNTHEIVEVSAARTIRIQQLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
FALDEITIRDKNIIIETDPNVLAKQFNQFKEDKQKALATADELIALSSSPERRVVNEEIK
HHHHHHEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RLLVDYLASAESGIGYGMKGDKGMAAKISGSTSREVRLKLIAEVNKRIAANLQELKAAKE
HHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RASEVAASATATLTAVAAAGLIAATALLAAIATFGVARPLNAMTTAMGRLASGDLDIAVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEE
GTNRRDEVGSLARSLQVFKDNAIEARQVAAAQEVENQAKMRRANLLDDLTKTFERSVSLL
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQGLAGAATEMEATARAMTATADETTHQSVSVAGAAQQTSANVQTVAAASEEMAASVAEI
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHH
VQQVSQSARIADRAVETARRTDATVQRLAGTAERISTAVSLISDIASQTNLLALNATIEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHH
ARAGEAGRGFAVVAAEVKELAGQTGRATSEIGERIAEIQAATQEAVTDIQQIGRVIGEMS
HHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TYAASIAAAMEEQGAATQEITRNVQQAAQGTEQVTHNIGSVQAGAGQTSAAASQVLSAAQ
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ELARHSEGLTHEVSTFLTGVKAA
HHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MRFLNNLRLTLKLAIPALVLIAVSVGMVLLARASLSTLDQNTHEIVEVSAARTIRIQQLA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
FALDEITIRDKNIIIETDPNVLAKQFNQFKEDKQKALATADELIALSSSPERRVVNEEIK
HHHHHHEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RLLVDYLASAESGIGYGMKGDKGMAAKISGSTSREVRLKLIAEVNKRIAANLQELKAAKE
HHHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
RASEVAASATATLTAVAAAGLIAATALLAAIATFGVARPLNAMTTAMGRLASGDLDIAVT
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEEE
GTNRRDEVGSLARSLQVFKDNAIEARQVAAAQEVENQAKMRRANLLDDLTKTFERSVSLL
CCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TQGLAGAATEMEATARAMTATADETTHQSVSVAGAAQQTSANVQTVAAASEEMAASVAEI
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHH
VQQVSQSARIADRAVETARRTDATVQRLAGTAERISTAVSLISDIASQTNLLALNATIEA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECHHHH
ARAGEAGRGFAVVAAEVKELAGQTGRATSEIGERIAEIQAATQEAVTDIQQIGRVIGEMS
HHCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TYAASIAAAMEEQGAATQEITRNVQQAAQGTEQVTHNIGSVQAGAGQTSAAASQVLSAAQ
HHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
ELARHSEGLTHEVSTFLTGVKAA
HHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]