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The map label for this gene is rlmM [H]

Identifier: 218710360

GI number: 218710360

Start: 2566786

End: 2567973

Strand: Reverse

Name: rlmM [H]

Synonym: VS_2396

Alternate gene names: 218710360

Gene position: 2567973-2566786 (Counterclockwise)

Preceding gene: 218710361

Following gene: 218710359

Centisome position: 77.83

GC content: 44.87

Gene sequence:

>1188_bases
ATGGTTTGGCCCTATAACACCGTTTGGTGGTCTACTATTTATCATTGGTTGGGGAGTCTTCTCCTTCGCTGCTTTGAATA
TAAAAGAGGTAACTCAGTGAAACACGTACTACTTTATTGTCGCTCTGGTTTTGAAAAAGAATGTGCTGGCGAAATTCAAG
ACAAGGCAACACAACTGGAAGTGTTTGGTTTTCCTCGCCTAAAGAACAATACCGGCTTTGTATTGTTTGAATGTTACCAA
GCAGGTGAAGCGGATAAGTTGATCAAAGAGATCGATTTCCAATCACTGATCTTTGCTCGTCAAATGCTAGCAGTAGCTGT
TGAAATCAAAGACCTGCCAACCGATGACCGTATTTCTCCAATTCTTGAGGCGCTTTCTGAGAAAGAAGGTTTCCCTCGTT
GTGGTGATATCCGTATCGAAACACCAGACACTAACGAAGCAAAAGAGCTTTTGAAGTTCTGCCGTAAGTTTACTGTGCCA
ATGCGTCAGGCAATGCGCGGTAAAGGGCTGATGACAGCGAAAGACAACGCTAAGAAGCCAGTGCTTCATTTATGCTTTAT
CGCTCCGGGTCACTGTTTTGTTGGTTACTCTTACCCAACTAACAACTCACAGTTCTTCATGGGTATTCCTCGTTTGAAAT
TCCCATCAGATGCGCCAAGCCGTTCTACATTGAAGCTAGAAGAAGCATTCCACGTATTCATCCCTCGTGATGAGTGGGAC
GAACGTCTGGCTCCGGGTATGTGGGGCGTAGATTTAGGCGCGTGTCCAGGTGGTTGGACTTACCAATTGGTTAAGCGCTC
TATGTTTGTTCACTGTGTTGATAACGGCATGATGGCAGACAGCCTAATGGAAACGGGTCAAATTAAGCACCACATGGTGG
ATGGTTTTAAATTCGAACCTGACCGTAAGAACGTCACTTGGATTATCTGTGACATGGTTGAGAAGCCGGCTCGTGTTGCT
CATTTAATGGGGGAGTGGATCATCAAAGGCTGGGCGAAAGAAGCACTGTTCAACCTTAAACTGCCAATGAAAGGCCGTTA
CGATGAAGTTCTGCAGGATATCGAAAACCTAAAACAGTTCCTGATTGATAACAAAGTGAAGTTCAAGATGCAGGCGAAGC
ACCTTTACCACGATCGCGAAGAGATCACGGTTCATATTCAGTCGCTTTCGAATATCTCACCGTACTAA

Upstream 100 bases:

>100_bases
CTAAATCACAAAAATATTTTTTCATTGCGGCAATTTGCTTTATCATCGGCATCCTTTGTTTTAGTGGCAGCCTTTATGGC
TTGGCATTGACAGGAATAAA

Downstream 100 bases:

>100_bases
TATTTACGTTAGTGTGTCAGTGATAAATAAAATGCTCCTTTAGGGGCATTTTTTATATCTTAAGTTTGTTTATGAGCTTG
ATTATCGCTTCGTACGGATA

Product: putative RNA 2'-O-ribose methyltransferase

Products: NA

Alternate protein names: 23S rRNA 2'-O-ribose methyltransferase rlmM [H]

Number of amino acids: Translated: 395; Mature: 395

Protein sequence:

>395_residues
MVWPYNTVWWSTIYHWLGSLLLRCFEYKRGNSVKHVLLYCRSGFEKECAGEIQDKATQLEVFGFPRLKNNTGFVLFECYQ
AGEADKLIKEIDFQSLIFARQMLAVAVEIKDLPTDDRISPILEALSEKEGFPRCGDIRIETPDTNEAKELLKFCRKFTVP
MRQAMRGKGLMTAKDNAKKPVLHLCFIAPGHCFVGYSYPTNNSQFFMGIPRLKFPSDAPSRSTLKLEEAFHVFIPRDEWD
ERLAPGMWGVDLGACPGGWTYQLVKRSMFVHCVDNGMMADSLMETGQIKHHMVDGFKFEPDRKNVTWIICDMVEKPARVA
HLMGEWIIKGWAKEALFNLKLPMKGRYDEVLQDIENLKQFLIDNKVKFKMQAKHLYHDREEITVHIQSLSNISPY

Sequences:

>Translated_395_residues
MVWPYNTVWWSTIYHWLGSLLLRCFEYKRGNSVKHVLLYCRSGFEKECAGEIQDKATQLEVFGFPRLKNNTGFVLFECYQ
AGEADKLIKEIDFQSLIFARQMLAVAVEIKDLPTDDRISPILEALSEKEGFPRCGDIRIETPDTNEAKELLKFCRKFTVP
MRQAMRGKGLMTAKDNAKKPVLHLCFIAPGHCFVGYSYPTNNSQFFMGIPRLKFPSDAPSRSTLKLEEAFHVFIPRDEWD
ERLAPGMWGVDLGACPGGWTYQLVKRSMFVHCVDNGMMADSLMETGQIKHHMVDGFKFEPDRKNVTWIICDMVEKPARVA
HLMGEWIIKGWAKEALFNLKLPMKGRYDEVLQDIENLKQFLIDNKVKFKMQAKHLYHDREEITVHIQSLSNISPY
>Mature_395_residues
MVWPYNTVWWSTIYHWLGSLLLRCFEYKRGNSVKHVLLYCRSGFEKECAGEIQDKATQLEVFGFPRLKNNTGFVLFECYQ
AGEADKLIKEIDFQSLIFARQMLAVAVEIKDLPTDDRISPILEALSEKEGFPRCGDIRIETPDTNEAKELLKFCRKFTVP
MRQAMRGKGLMTAKDNAKKPVLHLCFIAPGHCFVGYSYPTNNSQFFMGIPRLKFPSDAPSRSTLKLEEAFHVFIPRDEWD
ERLAPGMWGVDLGACPGGWTYQLVKRSMFVHCVDNGMMADSLMETGQIKHHMVDGFKFEPDRKNVTWIICDMVEKPARVA
HLMGEWIIKGWAKEALFNLKLPMKGRYDEVLQDIENLKQFLIDNKVKFKMQAKHLYHDREEITVHIQSLSNISPY

Specific function: Catalyzes the 2'-O-methylation at nucleotide C2498 in 23S rRNA [H]

COG id: COG2933

COG function: function code R; Predicted SAM-dependent methyltransferase

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. RlmE family. RlmM subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789171, Length=360, Percent_Identity=60, Blast_Score=468, Evalue=1e-133,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011224
- InterPro:   IPR002877 [H]

Pfam domain/function: PF01728 FtsJ [H]

EC number: NA

Molecular weight: Translated: 45680; Mature: 45680

Theoretical pI: Translated: 7.90; Mature: 7.90

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.8 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVWPYNTVWWSTIYHWLGSLLLRCFEYKRGNSVKHVLLYCRSGFEKECAGEIQDKATQLE
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHEEE
VFGFPRLKNNTGFVLFECYQAGEADKLIKEIDFQSLIFARQMLAVAVEIKDLPTDDRISP
EEECCEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
ILEALSEKEGFPRCGDIRIETPDTNEAKELLKFCRKFTVPMRQAMRGKGLMTAKDNAKKP
HHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCHHHHHHHCCCCCEECCCCCCCC
VLHLCFIAPGHCFVGYSYPTNNSQFFMGIPRLKFPSDAPSRSTLKLEEAFHVFIPRDEWD
EEEEEEECCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCEEEEECEEEEEECCCCHH
ERLAPGMWGVDLGACPGGWTYQLVKRSMFVHCVDNGMMADSLMETGQIKHHMVDGFKFEP
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCHHHHHHHHHCCHHHHHHCCEEECC
DRKNVTWIICDMVEKPARVAHLMGEWIIKGWAKEALFNLKLPMKGRYDEVLQDIENLKQF
CCCCEEEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHH
LIDNKVKFKMQAKHLYHDREEITVHIQSLSNISPY
HHCCCCEEEEHHHHHHCCCHHEEEEEEHHCCCCCC
>Mature Secondary Structure
MVWPYNTVWWSTIYHWLGSLLLRCFEYKRGNSVKHVLLYCRSGFEKECAGEIQDKATQLE
CCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHEEE
VFGFPRLKNNTGFVLFECYQAGEADKLIKEIDFQSLIFARQMLAVAVEIKDLPTDDRISP
EEECCEECCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
ILEALSEKEGFPRCGDIRIETPDTNEAKELLKFCRKFTVPMRQAMRGKGLMTAKDNAKKP
HHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHCHHHHHHHCCCCCEECCCCCCCC
VLHLCFIAPGHCFVGYSYPTNNSQFFMGIPRLKFPSDAPSRSTLKLEEAFHVFIPRDEWD
EEEEEEECCCCEEEEECCCCCCCEEEEECCCCCCCCCCCCCCEEEEECEEEEEECCCCHH
ERLAPGMWGVDLGACPGGWTYQLVKRSMFVHCVDNGMMADSLMETGQIKHHMVDGFKFEP
HHHCCCCCCCCCCCCCCCHHHHHHHHHHHEEECCCCHHHHHHHHHCCHHHHHHCCEEECC
DRKNVTWIICDMVEKPARVAHLMGEWIIKGWAKEALFNLKLPMKGRYDEVLQDIENLKQF
CCCCEEEEEEEHHHCHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHH
LIDNKVKFKMQAKHLYHDREEITVHIQSLSNISPY
HHCCCCEEEEHHHHHHCCCHHEEEEEEHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA