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The map label for this gene is cdsA [H]

Identifier: 218710313

GI number: 218710313

Start: 2517512

End: 2518354

Strand: Reverse

Name: cdsA [H]

Synonym: VS_2348

Alternate gene names: 218710313

Gene position: 2518354-2517512 (Counterclockwise)

Preceding gene: 218710314

Following gene: 218710312

Centisome position: 76.33

GC content: 42.23

Gene sequence:

>843_bases
TTGAAACAACGAATTATTACGGCGTTGATTTTAGCTCCCCTAGTTATTCTAGGTATTTTCGAGTTATCACTTCCCACGTT
TATTCTTTCACTAGCGGTAATCTCGCTACTGGGTTTTTGGGAGTGGACTCAGTTTGTTGAAAGCAAATCGCGTTCTTTAG
CGTTGATTCCAACAGTTGTGGTCAGTGCTGCAAGTTTTGCTTTTATACCTTTTGATGCATTTAGCCTTAATAACTTATCG
AGTGCTCACTATGCCATTCTGACGATTGGTTCAATTTGGTGGGTAATCGCAAGTGGTATGGCAGTGACTTATCCTAAGTC
TATGCCAGCATGGAAAGACTCATCAATTCTTCGTCACGCATTTGGCGTGCTGACTTTGCTACCATTCTTCTGGAGTGTAG
TTATCCTGCGTGCTAACGGTATCGATGTTGATCCTTACCACGGTGCAAAATTGGTGATGTTCGTTTGCTTGCTTGTTTGG
GCTGCAGACAGTGGTGCTTATTTTTCAGGAAAGAGCTTTGGCAAGCGAAAAATGGCCCCTGCGGTGAGTCCTAATAAAAC
GATTGAAGGTCTTATTGGTGGCATCATTACAGCAGTGATCGTGGCCTGGATCTTTGCTGACTTGTTTGATATCCAATTCA
CAAGTCCTCTCCACATGATTGTTATTACTCTTGTGACCGTCGTTATTTCAGTTCTTGGTGATCTTGTTGAAAGCATGTTT
AAACGTGTTTCTGGGGTGAAAGACAGCAGTAATCTGATTCCTGGTCATGGTGGTATACTTGATAGAATAGATAGCTTAAC
GGCTGCATTCCCTGTCTTTGCTCTGCTTTATTTAGCATTCTAA

Upstream 100 bases:

>100_bases
GTAGAAGCTGTGACTTGGTTTGTAAACCGCGAGCGTCGTTTTGGATGCACCGGTGAGCAAATTAAAGCTCTGATGGACAG
TTAATAAGGATTTTTTTGGT

Downstream 100 bases:

>100_bases
TAAAAAAGGGCAGTGATTCTGCCCTTTATTACATTCCTACGGTCATATGTGATGCGAAATCTAACTATCCTTGGCGCTAC
CGGCTCAATTGGTGCAAGTA

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 280; Mature: 280

Protein sequence:

>280_residues
MKQRIITALILAPLVILGIFELSLPTFILSLAVISLLGFWEWTQFVESKSRSLALIPTVVVSAASFAFIPFDAFSLNNLS
SAHYAILTIGSIWWVIASGMAVTYPKSMPAWKDSSILRHAFGVLTLLPFFWSVVILRANGIDVDPYHGAKLVMFVCLLVW
AADSGAYFSGKSFGKRKMAPAVSPNKTIEGLIGGIITAVIVAWIFADLFDIQFTSPLHMIVITLVTVVISVLGDLVESMF
KRVSGVKDSSNLIPGHGGILDRIDSLTAAFPVFALLYLAF

Sequences:

>Translated_280_residues
MKQRIITALILAPLVILGIFELSLPTFILSLAVISLLGFWEWTQFVESKSRSLALIPTVVVSAASFAFIPFDAFSLNNLS
SAHYAILTIGSIWWVIASGMAVTYPKSMPAWKDSSILRHAFGVLTLLPFFWSVVILRANGIDVDPYHGAKLVMFVCLLVW
AADSGAYFSGKSFGKRKMAPAVSPNKTIEGLIGGIITAVIVAWIFADLFDIQFTSPLHMIVITLVTVVISVLGDLVESMF
KRVSGVKDSSNLIPGHGGILDRIDSLTAAFPVFALLYLAF
>Mature_280_residues
MKQRIITALILAPLVILGIFELSLPTFILSLAVISLLGFWEWTQFVESKSRSLALIPTVVVSAASFAFIPFDAFSLNNLS
SAHYAILTIGSIWWVIASGMAVTYPKSMPAWKDSSILRHAFGVLTLLPFFWSVVILRANGIDVDPYHGAKLVMFVCLLVW
AADSGAYFSGKSFGKRKMAPAVSPNKTIEGLIGGIITAVIVAWIFADLFDIQFTSPLHMIVITLVTVVISVLGDLVESMF
KRVSGVKDSSNLIPGHGGILDRIDSLTAAFPVFALLYLAF

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=279, Percent_Identity=43.3691756272401, Blast_Score=218, Evalue=2e-58,
Organism=Escherichia coli, GI1787677, Length=116, Percent_Identity=47.4137931034483, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 30442; Mature: 30442

Theoretical pI: Translated: 9.00; Mature: 9.00

Prosite motif: PS01315 CDS ; PS00133 CARBOXYPEPT_ZN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQRIITALILAPLVILGIFELSLPTFILSLAVISLLGFWEWTQFVESKSRSLALIPTVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHH
VSAASFAFIPFDAFSLNNLSSAHYAILTIGSIWWVIASGMAVTYPKSMPAWKDSSILRHA
HHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHH
FGVLTLLPFFWSVVILRANGIDVDPYHGAKLVMFVCLLVWAADSGAYFSGKSFGKRKMAP
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCHHCCC
AVSPNKTIEGLIGGIITAVIVAWIFADLFDIQFTSPLHMIVITLVTVVISVLGDLVESMF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KRVSGVKDSSNLIPGHGGILDRIDSLTAAFPVFALLYLAF
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MKQRIITALILAPLVILGIFELSLPTFILSLAVISLLGFWEWTQFVESKSRSLALIPTVV
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHH
VSAASFAFIPFDAFSLNNLSSAHYAILTIGSIWWVIASGMAVTYPKSMPAWKDSSILRHA
HHHHHHHEECCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCEEECCCCCCCCCCHHHHHHH
FGVLTLLPFFWSVVILRANGIDVDPYHGAKLVMFVCLLVWAADSGAYFSGKSFGKRKMAP
HHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCEECCCCCCCHHCCC
AVSPNKTIEGLIGGIITAVIVAWIFADLFDIQFTSPLHMIVITLVTVVISVLGDLVESMF
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KRVSGVKDSSNLIPGHGGILDRIDSLTAAFPVFALLYLAF
HHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]