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The map label for this gene is cutC

Identifier: 218708614

GI number: 218708614

Start: 616261

End: 617004

Strand: Reverse

Name: cutC

Synonym: VS_0592

Alternate gene names: 218708614

Gene position: 617004-616261 (Counterclockwise)

Preceding gene: 218708615

Following gene: 218708613

Centisome position: 18.7

GC content: 44.49

Gene sequence:

>744_bases
ATGAACACCGAAATTGAAGTCTGTATCGATAACTTAGAATCTCTATATAACGCACTATCTGGTGGCGCGAATCGAATTGA
GCTTTGCTCTTCATTAGCACTTGGCGGGTTAACTCCAAGCTTCGGAATGATGAAGCAAGCGGCAAAAATTTCGTCCGTAC
CAGTTTATGCCATGATACGACCGAGACAAGGTGACTTCATATTCGATTATGACGATATACTCTGTATGCTGGAAGATATT
GAAGCTTGTGCGAGAGCAGGGGTGAATGGCGTCGTTCTGGGTGTACTAACACCTGATGGTGAGATTGATATGTCTGCAAT
GCAAATTCTCTCAAGCAAGGCTCACCAACTCAAACTAGCAATCACCTTCCACCGTGCAATCGACCAACTTCAGGATTATA
AAGTACCGTTAGAGCAGATTATTGAGCTTGGATGTGAAAGAATCCTGACGTCAGGACTTGCTATTAATGCAGAGCAAGGC
ATCAATGTGCTCGCAGATATGGTCAAACAAGCCGATGGCAGAATCGATATCATGGCTGGTGCTGGCGTCAACGCAACGAA
TGCCAAAATGATTCAAAGCACCACCCAAGTACCTGCACTTCACCTTTCAGGTAAATCGACAAGACCGAGTCTAATGGAAA
GCAATTCAAGCGCTCAAATGGGCAGTAATGATGTTGATGATTATCAGATACCAGTAACTGATGCGAATAAGATATCCAAT
GTGAGAGCTGCCCTCACCGCTTAG

Upstream 100 bases:

>100_bases
AAGAACAAACTTTACCCCTATTTTCCTCTGCTACCACCTATTCATATCCGTATCTAGGTTGTTATGATTTCGTCCGTATC
TTTTTGAACGGATAAATACG

Downstream 100 bases:

>100_bases
GGTAATCGTCACTAACACAAATCCAGAGAACCACGCTGACGAATCTAGCGGACTGGCGTATATTAGAGTGAATAGCACAG
AAAATTTTCATGGATAGATA

Product: Copper homeostasis protein CutC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MNTEIEVCIDNLESLYNALSGGANRIELCSSLALGGLTPSFGMMKQAAKISSVPVYAMIRPRQGDFIFDYDDILCMLEDI
EACARAGVNGVVLGVLTPDGEIDMSAMQILSSKAHQLKLAITFHRAIDQLQDYKVPLEQIIELGCERILTSGLAINAEQG
INVLADMVKQADGRIDIMAGAGVNATNAKMIQSTTQVPALHLSGKSTRPSLMESNSSAQMGSNDVDDYQIPVTDANKISN
VRAALTA

Sequences:

>Translated_247_residues
MNTEIEVCIDNLESLYNALSGGANRIELCSSLALGGLTPSFGMMKQAAKISSVPVYAMIRPRQGDFIFDYDDILCMLEDI
EACARAGVNGVVLGVLTPDGEIDMSAMQILSSKAHQLKLAITFHRAIDQLQDYKVPLEQIIELGCERILTSGLAINAEQG
INVLADMVKQADGRIDIMAGAGVNATNAKMIQSTTQVPALHLSGKSTRPSLMESNSSAQMGSNDVDDYQIPVTDANKISN
VRAALTA
>Mature_247_residues
MNTEIEVCIDNLESLYNALSGGANRIELCSSLALGGLTPSFGMMKQAAKISSVPVYAMIRPRQGDFIFDYDDILCMLEDI
EACARAGVNGVVLGVLTPDGEIDMSAMQILSSKAHQLKLAITFHRAIDQLQDYKVPLEQIIELGCERILTSGLAINAEQG
INVLADMVKQADGRIDIMAGAGVNATNAKMIQSTTQVPALHLSGKSTRPSLMESNSSAQMGSNDVDDYQIPVTDANKISN
VRAALTA

Specific function: Involved in copper homeostasis

COG id: COG3142

COG function: function code P; Uncharacterized protein involved in copper resistance

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CutC family

Homologues:

Organism=Homo sapiens, GI148596990, Length=245, Percent_Identity=40.8163265306122, Blast_Score=178, Evalue=3e-45,
Organism=Escherichia coli, GI87081995, Length=240, Percent_Identity=35, Blast_Score=138, Evalue=3e-34,
Organism=Caenorhabditis elegans, GI17556905, Length=203, Percent_Identity=41.3793103448276, Blast_Score=168, Evalue=2e-42,
Organism=Drosophila melanogaster, GI21355415, Length=239, Percent_Identity=34.7280334728033, Blast_Score=142, Evalue=3e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CUTC_VIBSL (B7VJR1)

Other databases:

- EMBL:   FM954972
- RefSeq:   YP_002416235.1
- ProteinModelPortal:   B7VJR1
- GeneID:   7160212
- GenomeReviews:   FM954972_GR
- KEGG:   vsp:VS_0592
- HOGENOM:   HBG535337
- OMA:   PVYAMIR
- ProtClustDB:   CLSK874089
- GO:   GO:0005737
- HAMAP:   MF_00795
- InterPro:   IPR005627
- Gene3D:   G3DSA:3.20.20.380
- PANTHER:   PTHR12598

Pfam domain/function: PF03932 CutC; SSF110395 CutC

EC number: NA

Molecular weight: Translated: 26408; Mature: 26408

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
6.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTEIEVCIDNLESLYNALSGGANRIELCSSLALGGLTPSFGMMKQAAKISSVPVYAMIR
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEE
PRQGDFIFDYDDILCMLEDIEACARAGVNGVVLGVLTPDGEIDMSAMQILSSKAHQLKLA
CCCCCEEECHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHEEEEE
ITFHRAIDQLQDYKVPLEQIIELGCERILTSGLAINAEQGINVLADMVKQADGRIDIMAG
EHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCCEEEEEC
AGVNATNAKMIQSTTQVPALHLSGKSTRPSLMESNSSAQMGSNDVDDYQIPVTDANKISN
CCCCCCCHHHHHHHHCCCEEEECCCCCCCHHHCCCCCCCCCCCCCCCCEECCCCCHHHHH
VRAALTA
HHHHHCC
>Mature Secondary Structure
MNTEIEVCIDNLESLYNALSGGANRIELCSSLALGGLTPSFGMMKQAAKISSVPVYAMIR
CCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCEEEEEE
PRQGDFIFDYDDILCMLEDIEACARAGVNGVVLGVLTPDGEIDMSAMQILSSKAHQLKLA
CCCCCEEECHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHEEEEE
ITFHRAIDQLQDYKVPLEQIIELGCERILTSGLAINAEQGINVLADMVKQADGRIDIMAG
EHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCEEEHHHHHHHHHHHHHHCCCCEEEEEC
AGVNATNAKMIQSTTQVPALHLSGKSTRPSLMESNSSAQMGSNDVDDYQIPVTDANKISN
CCCCCCCHHHHHHHHCCCEEEECCCCCCCHHHCCCCCCCCCCCCCCCCEECCCCCHHHHH
VRAALTA
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA