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The map label for this gene is nahR [H]

Identifier: 218708613

GI number: 218708613

Start: 615232

End: 616161

Strand: Reverse

Name: nahR [H]

Synonym: VS_0591

Alternate gene names: 218708613

Gene position: 616161-615232 (Counterclockwise)

Preceding gene: 218708614

Following gene: 218708611

Centisome position: 18.68

GC content: 40.32

Gene sequence:

>930_bases
ATGGCTAAAGACCTATTCAGCTCTCTTGATTTAAACCTGTTACGAACATTTCTGATTGTTTATCAAGAAAAAAACACCAG
AAAGGCTGCGGAACGTTTATTCGTTTCTCAGCCAGCGGTTAGCCAAGCCCTACAAAAGCTAAGACACCACTTCAACGATG
ATCTTTTCGTAAAGGTTCATGGAGGCTTACAACCTACGGCATTTTCAGAGCAGCTCACCAATCAAATCAAGCCGTTCATG
GACGGTCTATCTATCGCGGTTAATACATCAAACACTTTTGATCCGAAAGAGATCGATTACACGTTGAAAATAGCCCTATC
TCCAGTGGTGCTTTCTTGTCTGTCTGGCTCACTTTTTAAAGATATAAAAGCGCAAGCACCAAACGCTAAACTAAAGCTTG
TTCCATGGTCAAACTCGTCTGTCTCAGATATACAAAAAGATGAGGTTTTGATGGGAGTAAGCTATTTAGGGGAAAAGACA
AGTAAAGAAGTCTATACAAGGCAGCTCATTGAATTAACAGGACGTATATTTGTTAGGAAAGATCACCCTTTAAAGCAAGA
CACCGTGACTCCAAATGACATGGCAGGGTACGAAATCGCATCTTTAGTAACACCAGGTTGGAATGACAATTTTAGCTTAG
CGTCTCAGATTCTAACCGACCTTTCCATCGAGCATCGTATCGGTTTTCGCAGCGAATTGGTCATGGCTATAATCGATGTC
ATTCAACATACTGATATGTACATGCCCCATTCCAACCTTTTCCCAGTAGAAAACTATCCGACATTACGCGGGATAGATGT
CTCAGTCGACGGAAAAACGCTGAAAACTCCGGTCTATAGTTATATACACATTAAAAATCGAAACTCACCTTTAACAAATT
GGCTTTCAAAACTCATAGAGCAAGTTTTATCAGAACAAGTACAAAAGTAA

Upstream 100 bases:

>100_bases
GGGTAATCGTCACTAACACAAATCCAGAGAACCACGCTGACGAATCTAGCGGACTGGCGTATATTAGAGTGAATAGCACA
GAAAATTTTCATGGATAGAT

Downstream 100 bases:

>100_bases
GTTCGATTAAAAGTTATATATTGTATTTTACTCTTCCGGACGCCAGCTCAGTGCGCTAGCAATAGTACCGATAACTAATG
TGTCTTTTTCAGCGTCATTA

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MAKDLFSSLDLNLLRTFLIVYQEKNTRKAAERLFVSQPAVSQALQKLRHHFNDDLFVKVHGGLQPTAFSEQLTNQIKPFM
DGLSIAVNTSNTFDPKEIDYTLKIALSPVVLSCLSGSLFKDIKAQAPNAKLKLVPWSNSSVSDIQKDEVLMGVSYLGEKT
SKEVYTRQLIELTGRIFVRKDHPLKQDTVTPNDMAGYEIASLVTPGWNDNFSLASQILTDLSIEHRIGFRSELVMAIIDV
IQHTDMYMPHSNLFPVENYPTLRGIDVSVDGKTLKTPVYSYIHIKNRNSPLTNWLSKLIEQVLSEQVQK

Sequences:

>Translated_309_residues
MAKDLFSSLDLNLLRTFLIVYQEKNTRKAAERLFVSQPAVSQALQKLRHHFNDDLFVKVHGGLQPTAFSEQLTNQIKPFM
DGLSIAVNTSNTFDPKEIDYTLKIALSPVVLSCLSGSLFKDIKAQAPNAKLKLVPWSNSSVSDIQKDEVLMGVSYLGEKT
SKEVYTRQLIELTGRIFVRKDHPLKQDTVTPNDMAGYEIASLVTPGWNDNFSLASQILTDLSIEHRIGFRSELVMAIIDV
IQHTDMYMPHSNLFPVENYPTLRGIDVSVDGKTLKTPVYSYIHIKNRNSPLTNWLSKLIEQVLSEQVQK
>Mature_308_residues
AKDLFSSLDLNLLRTFLIVYQEKNTRKAAERLFVSQPAVSQALQKLRHHFNDDLFVKVHGGLQPTAFSEQLTNQIKPFMD
GLSIAVNTSNTFDPKEIDYTLKIALSPVVLSCLSGSLFKDIKAQAPNAKLKLVPWSNSSVSDIQKDEVLMGVSYLGEKTS
KEVYTRQLIELTGRIFVRKDHPLKQDTVTPNDMAGYEIASLVTPGWNDNFSLASQILTDLSIEHRIGFRSELVMAIIDVI
QHTDMYMPHSNLFPVENYPTLRGIDVSVDGKTLKTPVYSYIHIKNRNSPLTNWLSKLIEQVLSEQVQK

Specific function: Regulates the expression of the naphthalene (nahA-F) and salicylate (nahG-M) metabolism genes [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081684, Length=254, Percent_Identity=25.9842519685039, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786820, Length=270, Percent_Identity=26.2962962962963, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI87081766, Length=267, Percent_Identity=26.5917602996255, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790147, Length=305, Percent_Identity=26.5573770491803, Blast_Score=71, Evalue=1e-13,

Paralogues:

None

Copy number: 825 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34882; Mature: 34750

Theoretical pI: Translated: 7.81; Mature: 7.81

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKDLFSSLDLNLLRTFLIVYQEKNTRKAAERLFVSQPAVSQALQKLRHHFNDDLFVKVH
CCHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEC
GGLQPTAFSEQLTNQIKPFMDGLSIAVNTSNTFDPKEIDYTLKIALSPVVLSCLSGSLFK
CCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHCCEEEEEHHHHHHHHHHCCHHHH
DIKAQAPNAKLKLVPWSNSSVSDIQKDEVLMGVSYLGEKTSKEVYTRQLIELTGRIFVRK
HHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEC
DHPLKQDTVTPNDMAGYEIASLVTPGWNDNFSLASQILTDLSIEHRIGFRSELVMAIIDV
CCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHCCHHHHHHHHHHHH
IQHTDMYMPHSNLFPVENYPTLRGIDVSVDGKTLKTPVYSYIHIKNRNSPLTNWLSKLIE
HHHCCCCCCCCCCCCCCCCCCEECEEEEECCCEECCCCEEEEEEECCCCHHHHHHHHHHH
QVLSEQVQK
HHHHHHHCC
>Mature Secondary Structure 
AKDLFSSLDLNLLRTFLIVYQEKNTRKAAERLFVSQPAVSQALQKLRHHFNDDLFVKVH
CHHHHHHCCHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEC
GGLQPTAFSEQLTNQIKPFMDGLSIAVNTSNTFDPKEIDYTLKIALSPVVLSCLSGSLFK
CCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHCCEEEEEHHHHHHHHHHCCHHHH
DIKAQAPNAKLKLVPWSNSSVSDIQKDEVLMGVSYLGEKTSKEVYTRQLIELTGRIFVRK
HHHHCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCEEEEC
DHPLKQDTVTPNDMAGYEIASLVTPGWNDNFSLASQILTDLSIEHRIGFRSELVMAIIDV
CCCCCCCCCCCCCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCHHHHCCHHHHHHHHHHHH
IQHTDMYMPHSNLFPVENYPTLRGIDVSVDGKTLKTPVYSYIHIKNRNSPLTNWLSKLIE
HHHCCCCCCCCCCCCCCCCCCEECEEEEECCCEECCCCEEEEEEECCCCHHHHHHHHHHH
QVLSEQVQK
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2703465; 2848005 [H]