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The map label for this gene is atoE

Identifier: 218700692

GI number: 218700692

Start: 2436847

End: 2438169

Strand: Direct

Name: atoE

Synonym: ECIAI39_2361

Alternate gene names: 218700692

Gene position: 2436847-2438169 (Clockwise)

Preceding gene: 218700691

Following gene: 218700693

Centisome position: 47.48

GC content: 53.06

Gene sequence:

>1323_bases
ATGATTGGTCGCATATCGCGTTTTATGACGCGTTTTGTCAGCCGGTGGCTTCCCGATCCACTGATCTTTGCCATGTTGCT
GACATTGCTAACATTCGTGATCGCGCTTTGGTTAACACCACAAACGCCGATCAGCATGGTGAAAATGTGGGGTGACGGTT
TCTGGAACTTGCTGGCGTTTGGTATGCAGATGGCGCTTATCATCGTTACCGGTCATGCCCTTGCCAGCTCTGCTCCGGTA
AAAAGTTTGCTGCGTACTGCCGCCTCCGCCGCAAAGACGCCCGTACAGGGCGTCATGCTGGTTACTTTCTTCGGTTCAGT
CGCTTGTGTCATCAACTGGGGATTTGGTTTGGTTGTCGGCGCAATGTTTGCCCGTGAAGTCGCCCGCCGAGTACCCGGTT
CTGATTATCCGTTGCTCATTGCCTGCGCCTACATTGGTTTTCTCACCTGGGGTGGCGGTTTCTCTGGCTCAATGCCTCTG
TTGGCTGCAACACCGGGCAACCCGGTTGAGCATATCGCCGGGCTGATCCCGGTGGGCGATACTCTGTTCAGTGGTTTTAA
CATTTTCATCACTGTGGCGTTGATTGTGGTGATGCCATTTATCACCCGCATGATGATGCCAAAACCGTCTGACGTGGTGA
GTATCGATCCGAAACTACTCATGGAAGAGGCTGATTTCCAAAAGCAGCTACCGAAAGATGCCCCACCATCCGAGCGACTG
GAAGAAAGCCGCATTCTGACGTTGATCATCGGCGCACTCGGTATCGCTTACCTTGCGATGTACTTCAGCGAACATGGCTT
CAACATCACCATCAATACCGTCAACCTGATGTTTATGATTGCGGGTCTGCTGCTACATAAAACGCCAATGGCTTATATGC
GTGCTATCAGCGCGGCAGCACGCAGTACTGCCGGTATTCTGGTGCAATTCCCCTTCTACGCTGGGATCCAACTGATGATG
GAGCATTCCGGTCTGGGCGGACTCATTACCGAATTCTTCATCAATGTTGCGAACAAAGACACCTTCCCGGTAATGACCTT
TTTTAGTTCTGCACTGATTAACTTCGCCGTTCCGTCTGGCGGCGGTCACTGGGTTATTCAGGGACCTTTCGTGATACCCG
CAGCCCAGGCGCTGGGCGCTGATCTCGGTAAATCGGTAATGGCGATCGCCTACGGCGAGCAATGGATGAACATGGCACAA
CCGTTCTGGGCGCTGCCAGCACTGGCAATCGCCGGACTCGGTGTCCGCGACATCATGGGCTATTGCATCACTGCCCTGCT
CTTCTCCGGCGTCATTTTCGTCATTGGTTTAACGCTGTTCTGA

Upstream 100 bases:

>100_bases
TCACCGAAATTGCCGACGGGTGTGATTTAGCCACCGTGCGTGCCAAAACAGAAGCTCGGTTTGAAGTAGCTGCCGATCTG
AATACGCAACGGGGTGATTT

Downstream 100 bases:

>100_bases
CGGCAACCCTACAGACAGAAGGAATATAAAATGAAAAATTGTGTCATCGTCAGTGCGGTACGTACTGCTATCGGTAGTTT
TAACGGTTCACTCGCTTCCA

Product: short chain fatty acid transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 440; Mature: 440

Protein sequence:

>440_residues
MIGRISRFMTRFVSRWLPDPLIFAMLLTLLTFVIALWLTPQTPISMVKMWGDGFWNLLAFGMQMALIIVTGHALASSAPV
KSLLRTAASAAKTPVQGVMLVTFFGSVACVINWGFGLVVGAMFAREVARRVPGSDYPLLIACAYIGFLTWGGGFSGSMPL
LAATPGNPVEHIAGLIPVGDTLFSGFNIFITVALIVVMPFITRMMMPKPSDVVSIDPKLLMEEADFQKQLPKDAPPSERL
EESRILTLIIGALGIAYLAMYFSEHGFNITINTVNLMFMIAGLLLHKTPMAYMRAISAAARSTAGILVQFPFYAGIQLMM
EHSGLGGLITEFFINVANKDTFPVMTFFSSALINFAVPSGGGHWVIQGPFVIPAAQALGADLGKSVMAIAYGEQWMNMAQ
PFWALPALAIAGLGVRDIMGYCITALLFSGVIFVIGLTLF

Sequences:

>Translated_440_residues
MIGRISRFMTRFVSRWLPDPLIFAMLLTLLTFVIALWLTPQTPISMVKMWGDGFWNLLAFGMQMALIIVTGHALASSAPV
KSLLRTAASAAKTPVQGVMLVTFFGSVACVINWGFGLVVGAMFAREVARRVPGSDYPLLIACAYIGFLTWGGGFSGSMPL
LAATPGNPVEHIAGLIPVGDTLFSGFNIFITVALIVVMPFITRMMMPKPSDVVSIDPKLLMEEADFQKQLPKDAPPSERL
EESRILTLIIGALGIAYLAMYFSEHGFNITINTVNLMFMIAGLLLHKTPMAYMRAISAAARSTAGILVQFPFYAGIQLMM
EHSGLGGLITEFFINVANKDTFPVMTFFSSALINFAVPSGGGHWVIQGPFVIPAAQALGADLGKSVMAIAYGEQWMNMAQ
PFWALPALAIAGLGVRDIMGYCITALLFSGVIFVIGLTLF
>Mature_440_residues
MIGRISRFMTRFVSRWLPDPLIFAMLLTLLTFVIALWLTPQTPISMVKMWGDGFWNLLAFGMQMALIIVTGHALASSAPV
KSLLRTAASAAKTPVQGVMLVTFFGSVACVINWGFGLVVGAMFAREVARRVPGSDYPLLIACAYIGFLTWGGGFSGSMPL
LAATPGNPVEHIAGLIPVGDTLFSGFNIFITVALIVVMPFITRMMMPKPSDVVSIDPKLLMEEADFQKQLPKDAPPSERL
EESRILTLIIGALGIAYLAMYFSEHGFNITINTVNLMFMIAGLLLHKTPMAYMRAISAAARSTAGILVQFPFYAGIQLMM
EHSGLGGLITEFFINVANKDTFPVMTFFSSALINFAVPSGGGHWVIQGPFVIPAAQALGADLGKSVMAIAYGEQWMNMAQ
PFWALPALAIAGLGVRDIMGYCITALLFSGVIFVIGLTLF

Specific function: Responsible for the intake of short-chain fatty acids

COG id: COG2031

COG function: function code I; Short chain fatty acids transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788553, Length=440, Percent_Identity=100, Blast_Score=880, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ATOE_ECOLI (P76460)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   E64992
- RefSeq:   AP_002822.1
- RefSeq:   NP_416727.1
- ProteinModelPortal:   P76460
- STRING:   P76460
- EnsemblBacteria:   EBESCT00000002160
- EnsemblBacteria:   EBESCT00000014270
- GeneID:   946721
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW2217
- KEGG:   eco:b2223
- EchoBASE:   EB1622
- EcoGene:   EG11671
- eggNOG:   COG2031
- GeneTree:   EBGT00050000012097
- HOGENOM:   HBG697931
- OMA:   LGFSMQM
- ProtClustDB:   CLSK2301701
- BioCyc:   EcoCyc:EG11671-MONOMER
- Genevestigator:   P76460
- InterPro:   IPR006161
- InterPro:   IPR006160
- TIGRFAMs:   TIGR00366

Pfam domain/function: PF02667 SCFA_trans

EC number: NA

Molecular weight: Translated: 47528; Mature: 47528

Theoretical pI: Translated: 8.46; Mature: 8.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x2228fff8)-; HASH(0x2335e720)-; HASH(0x22fe7200)-; HASH(0x23501498)-; HASH(0x226408f4)-; HASH(0x236ab11c)-; HASH(0x22d48534)-; HASH(0x2350c0b8)-; HASH(0x23332548)-; HASH(0x233f4140)-; HASH(0x22ed4bd8)-; HASH(0x22f6300c)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
6.1 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
6.1 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGRISRFMTRFVSRWLPDPLIFAMLLTLLTFVIALWLTPQTPISMVKMWGDGFWNLLAF
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHH
GMQMALIIVTGHALASSAPVKSLLRTAASAAKTPVQGVMLVTFFGSVACVINWGFGLVVG
HHHHHHHHEECHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
AMFAREVARRVPGSDYPLLIACAYIGFLTWGGGFSGSMPLLAATPGNPVEHIAGLIPVGD
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHCCCCH
TLFSGFNIFITVALIVVMPFITRMMMPKPSDVVSIDPKLLMEEADFQKQLPKDAPPSERL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCHHHH
EESRILTLIIGALGIAYLAMYFSEHGFNITINTVNLMFMIAGLLLHKTPMAYMRAISAAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RSTAGILVQFPFYAGIQLMMEHSGLGGLITEFFINVANKDTFPVMTFFSSALINFAVPSG
HCCCCEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
GGHWVIQGPFVIPAAQALGADLGKSVMAIAYGEQWMNMAQPFWALPALAIAGLGVRDIMG
CCEEEEECCEECHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHH
YCITALLFSGVIFVIGLTLF
HHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MIGRISRFMTRFVSRWLPDPLIFAMLLTLLTFVIALWLTPQTPISMVKMWGDGFWNLLAF
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCHHHHHHHH
GMQMALIIVTGHALASSAPVKSLLRTAASAAKTPVQGVMLVTFFGSVACVINWGFGLVVG
HHHHHHHHEECHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCHHHHHH
AMFAREVARRVPGSDYPLLIACAYIGFLTWGGGFSGSMPLLAATPGNPVEHIAGLIPVGD
HHHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEECCCCHHHHHHHHCCCCH
TLFSGFNIFITVALIVVMPFITRMMMPKPSDVVSIDPKLLMEEADFQKQLPKDAPPSERL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCHHHHHHHHHHHHHCCCCCCCHHHH
EESRILTLIIGALGIAYLAMYFSEHGFNITINTVNLMFMIAGLLLHKTPMAYMRAISAAA
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHCCHHHHHHHHHHHH
RSTAGILVQFPFYAGIQLMMEHSGLGGLITEFFINVANKDTFPVMTFFSSALINFAVPSG
HCCCCEEEEECHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCC
GGHWVIQGPFVIPAAQALGADLGKSVMAIAYGEQWMNMAQPFWALPALAIAGLGVRDIMG
CCEEEEECCEECHHHHHHHHHHCHHHHHHHHHHHHHHHHCHHHHHHHHHHHCCCHHHHHH
YCITALLFSGVIFVIGLTLF
HHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503