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The map label for this gene is atoA

Identifier: 218700691

GI number: 218700691

Start: 2436200

End: 2436850

Strand: Direct

Name: atoA

Synonym: ECIAI39_2360

Alternate gene names: 218700691

Gene position: 2436200-2436850 (Clockwise)

Preceding gene: 218700690

Following gene: 218700692

Centisome position: 47.47

GC content: 53.3

Gene sequence:

>651_bases
ATGGATGCGAAACAACGTATTGCGCGCCGTGTGGCGCAAGAGCTTCGTGATGGTGACATCGTTAACTTAGGGATCGGTTT
ACCCACAATGGTCGCCAATTATTTACCGGAGGGTATTCATATCACTCTGCAATCGGAAAACGGCTTCCTCGGTTTAGGCC
CGGTCACGACAGCGCATCCAGATCTGGTGAACGCTGGCGGACAACCGTGCGGCATTTTACCCGGCGCAGCCATGTTTGAT
AGCGCCATGTCATTTGCGCTAATCCGTGGCGGTCATATTGATGCCTGCGTGCTCGGCGGTTTGCAAGTAGACGAAGAAGC
AAACCTCGCGAACTGGGTAGTGCCTGGGAAAATGGTGCCCGGTATGGGTGGCGCGATGGATCTGGTGACCGGGTCGCGCA
AAGTGATCATCGCCATGGAACATTGCGCCAAAGATGGTTCAGCAAAAATTTTGCGCCGCTGCACCATGCCACTCACTGCG
CAACATGCGGTGCATATGCTGGTTACTGAACTGGCTGTCTTTCGTTTTATTGACGGCAAAATGTGGCTCACCGAAATTGC
CGACGGGTGTGATTTAGCCACCGTGCGTGCCAAAACAGAAGCTCGGTTTGAAGTAGCTGCCGATCTGAATACGCAACGGG
GTGATTTATGA

Upstream 100 bases:

>100_bases
AGCCAGATGAACTGGTCGAAACCGGCGAGCTGCAACCTGACCATATTGTCACCCCTGGTGCCGTTATCGACCACATCATC
GTTTCACAGGAGAGCAAATA

Downstream 100 bases:

>100_bases
TTGGTCGCATATCGCGTTTTATGACGCGTTTTGTCAGCCGGTGGCTTCCCGATCCACTGATCTTTGCCATGTTGCTGACA
TTGCTAACATTCGTGATCGC

Product: acetyl-CoA:acetoacetyl-CoA transferase subunit beta

Products: NA

Alternate protein names: Acetyl-CoA:acetoacetate-CoA transferase subunit beta [H]

Number of amino acids: Translated: 216; Mature: 216

Protein sequence:

>216_residues
MDAKQRIARRVAQELRDGDIVNLGIGLPTMVANYLPEGIHITLQSENGFLGLGPVTTAHPDLVNAGGQPCGILPGAAMFD
SAMSFALIRGGHIDACVLGGLQVDEEANLANWVVPGKMVPGMGGAMDLVTGSRKVIIAMEHCAKDGSAKILRRCTMPLTA
QHAVHMLVTELAVFRFIDGKMWLTEIADGCDLATVRAKTEARFEVAADLNTQRGDL

Sequences:

>Translated_216_residues
MDAKQRIARRVAQELRDGDIVNLGIGLPTMVANYLPEGIHITLQSENGFLGLGPVTTAHPDLVNAGGQPCGILPGAAMFD
SAMSFALIRGGHIDACVLGGLQVDEEANLANWVVPGKMVPGMGGAMDLVTGSRKVIIAMEHCAKDGSAKILRRCTMPLTA
QHAVHMLVTELAVFRFIDGKMWLTEIADGCDLATVRAKTEARFEVAADLNTQRGDL
>Mature_216_residues
MDAKQRIARRVAQELRDGDIVNLGIGLPTMVANYLPEGIHITLQSENGFLGLGPVTTAHPDLVNAGGQPCGILPGAAMFD
SAMSFALIRGGHIDACVLGGLQVDEEANLANWVVPGKMVPGMGGAMDLVTGSRKVIIAMEHCAKDGSAKILRRCTMPLTA
QHAVHMLVTELAVFRFIDGKMWLTEIADGCDLATVRAKTEARFEVAADLNTQRGDL

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG2057

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit B family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=214, Percent_Identity=47.6635514018692, Blast_Score=197, Evalue=4e-51,
Organism=Homo sapiens, GI11545841, Length=213, Percent_Identity=45.5399061032864, Blast_Score=189, Evalue=1e-48,
Organism=Escherichia coli, GI1788552, Length=216, Percent_Identity=99.537037037037, Blast_Score=441, Evalue=1e-125,
Organism=Caenorhabditis elegans, GI17531517, Length=213, Percent_Identity=45.5399061032864, Blast_Score=184, Evalue=3e-47,
Organism=Drosophila melanogaster, GI21358325, Length=211, Percent_Identity=50.2369668246445, Blast_Score=213, Evalue=8e-56,
Organism=Drosophila melanogaster, GI24655794, Length=211, Percent_Identity=50.2369668246445, Blast_Score=213, Evalue=9e-56,

Paralogues:

None

Copy number: 369 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012791
- InterPro:   IPR004165
- InterPro:   IPR004164 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.8 [H]

Molecular weight: Translated: 22974; Mature: 22974

Theoretical pI: Translated: 5.93; Mature: 5.93

Prosite motif: PS01274 COA_TRANSF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
7.4 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
7.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAKQRIARRVAQELRDGDIVNLGIGLPTMVANYLPEGIHITLQSENGFLGLGPVTTAHP
CCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCC
DLVNAGGQPCGILPGAAMFDSAMSFALIRGGHIDACVLGGLQVDEEANLANWVVPGKMVP
HHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCEEECCCCCCCCEEECCCCCC
GMGGAMDLVTGSRKVIIAMEHCAKDGSAKILRRCTMPLTAQHAVHMLVTELAVFRFIDGK
CCCCCEEEECCCCEEEEEEHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
MWLTEIADGCDLATVRAKTEARFEVAADLNTQRGDL
EEEHHHCCCCCEEEEECCCCCEEEEEECCCCCCCCC
>Mature Secondary Structure
MDAKQRIARRVAQELRDGDIVNLGIGLPTMVANYLPEGIHITLQSENGFLGLGPVTTAHP
CCHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHCCCCEEEEEECCCCEEECCCCCCCCC
DLVNAGGQPCGILPGAAMFDSAMSFALIRGGHIDACVLGGLQVDEEANLANWVVPGKMVP
HHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCEEEECCEEECCCCCCCCEEECCCCCC
GMGGAMDLVTGSRKVIIAMEHCAKDGSAKILRRCTMPLTAQHAVHMLVTELAVFRFIDGK
CCCCCEEEECCCCEEEEEEHHHCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCC
MWLTEIADGCDLATVRAKTEARFEVAADLNTQRGDL
EEEHHHCCCCCEEEEECCCCCEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]