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The map label for this gene is ydjG

Identifier: 218695330

GI number: 218695330

Start: 2003422

End: 2004402

Strand: Reverse

Name: ydjG

Synonym: EC55989_1940

Alternate gene names: 218695330

Gene position: 2004402-2003422 (Counterclockwise)

Preceding gene: 218695331

Following gene: 218695329

Centisome position: 38.88

GC content: 47.71

Gene sequence:

>981_bases
ATGAAAAAGATACCTTTAGGCACAACGGATATTACGCTTTCGCGAATGGGGTTGGGGACATGGGCCATTGGCGGCGGTCC
TGCATGGAATGGCGATCTCGATCGGCAAATATGTATTGATACTATTCTTGAAGCCCATCGTTGTGGCATTAATCTGATTG
ATACTGCGCCAGGATATAACTTTGGCAATAGTGAAGTTATCGTCGGTCAGGCGTTAAAAAAACTGCCCCGTGAACAGGTT
GTAGTAGAAACCAAATGCGGCATTGTCTGGGAACGAAAAGGAAGTTTATTCAACAAAGTTGGCGATCGGCAGTTGTATAA
AAACCTTTCCCCGGAATCTATCCGCGAAGAGGTAGCAGCGAGCTTGCAACGTCTGGGTATTGATTACATCGATATCTACA
TGACGCACTGGCAGTCGGTGCCGCCATTTTTTACGCCGATCGCTGAAACTGTCGCAGTGCTTAATGAGTTAAAGTCTGAA
GGGAAAATTCGCGCTATAGGCGCTGCTAACGTCGATGCTGACCATATCCGCGAGTATCTGCAATATGGTGAACTGGATAT
TATTCAGGCGAAATACAGTATCCTCGACCGGGCAATGGAAAACGAACTGCTGCCACTATGTCGTGATAATGGCATTGTGG
TTCAGGTTTATTCCCCGCTAGAGCAGGGATTGTTGACCGGCACCATCACTCGTGATTACGTTCCGGGCGGCGCTCGGGCA
AATAAAGTCTGGTTCCAGCGTGAAAACATGCTGAAAGTGATTGATATGCTTGAACAGTGGCAGCCACTTTGTGCTCGTTA
TCAGTGCACAATTCCCACTCTGGCACTGGCGTGGATATTAAAACAGAGTGATTTAATCTCCATTCTTAGTGGGGCTACTG
CACCGGAACAGGTACGCGAAAATGTCGCGGCACTGAATATCAACTTATCGGATGCAGACGCAACATTGATGAGGGAAATG
GCAGAGGCCCTGGAGCGTTAA

Upstream 100 bases:

>100_bases
GGCGGCTATCTCGGTTCTAAGCGTCGGTGCCACCACCGGCGTAAAAAACAGAAAGCTGGTCGAACAATTGCTGGAAGAAT
ACGAAGGATAATGAAGGCAA

Downstream 100 bases:

>100_bases
ATACTCAACACGATTCACCTCTGTTTCTGTGAAAACTGTGATGAAAATCTGTGATTCAAACAGGTTATTTTGAAAGTAAA
CATCGGTTATGCGATAATCG

Product: putative oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 326; Mature: 326

Protein sequence:

>326_residues
MKKIPLGTTDITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILEAHRCGINLIDTAPGYNFGNSEVIVGQALKKLPREQV
VVETKCGIVWERKGSLFNKVGDRQLYKNLSPESIREEVAASLQRLGIDYIDIYMTHWQSVPPFFTPIAETVAVLNELKSE
GKIRAIGAANVDADHIREYLQYGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYSPLEQGLLTGTITRDYVPGGARA
NKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLALAWILKQSDLISILSGATAPEQVRENVAALNINLSDADATLMREM
AEALER

Sequences:

>Translated_326_residues
MKKIPLGTTDITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILEAHRCGINLIDTAPGYNFGNSEVIVGQALKKLPREQV
VVETKCGIVWERKGSLFNKVGDRQLYKNLSPESIREEVAASLQRLGIDYIDIYMTHWQSVPPFFTPIAETVAVLNELKSE
GKIRAIGAANVDADHIREYLQYGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYSPLEQGLLTGTITRDYVPGGARA
NKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLALAWILKQSDLISILSGATAPEQVRENVAALNINLSDADATLMREM
AEALER
>Mature_326_residues
MKKIPLGTTDITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILEAHRCGINLIDTAPGYNFGNSEVIVGQALKKLPREQV
VVETKCGIVWERKGSLFNKVGDRQLYKNLSPESIREEVAASLQRLGIDYIDIYMTHWQSVPPFFTPIAETVAVLNELKSE
GKIRAIGAANVDADHIREYLQYGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYSPLEQGLLTGTITRDYVPGGARA
NKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLALAWILKQSDLISILSGATAPEQVRENVAALNINLSDADATLMREM
AEALER

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family

Homologues:

Organism=Homo sapiens, GI27436964, Length=323, Percent_Identity=30.3405572755418, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI27436966, Length=318, Percent_Identity=30.188679245283, Blast_Score=119, Evalue=5e-27,
Organism=Homo sapiens, GI27436962, Length=318, Percent_Identity=30.188679245283, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI4504825, Length=335, Percent_Identity=28.0597014925373, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI27436969, Length=335, Percent_Identity=28.0597014925373, Blast_Score=108, Evalue=5e-24,
Organism=Homo sapiens, GI27436971, Length=327, Percent_Identity=28.1345565749235, Blast_Score=93, Evalue=3e-19,
Organism=Homo sapiens, GI223718702, Length=283, Percent_Identity=27.208480565371, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI41327764, Length=281, Percent_Identity=25.9786476868327, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI41152114, Length=282, Percent_Identity=26.241134751773, Blast_Score=79, Evalue=5e-15,
Organism=Escherichia coli, GI1788070, Length=326, Percent_Identity=100, Blast_Score=670, Evalue=0.0,
Organism=Escherichia coli, GI87081735, Length=324, Percent_Identity=33.9506172839506, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1789199, Length=341, Percent_Identity=29.0322580645161, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1788081, Length=313, Percent_Identity=27.4760383386581, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1789375, Length=318, Percent_Identity=26.7295597484277, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787674, Length=309, Percent_Identity=25.5663430420712, Blast_Score=79, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17564128, Length=335, Percent_Identity=25.0746268656716, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI212645785, Length=171, Percent_Identity=35.0877192982456, Blast_Score=74, Evalue=9e-14,
Organism=Caenorhabditis elegans, GI17552492, Length=315, Percent_Identity=24.4444444444444, Blast_Score=68, Evalue=7e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=339, Percent_Identity=24.4837758112094, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323998, Length=331, Percent_Identity=24.4712990936556, Blast_Score=76, Evalue=7e-15,
Organism=Saccharomyces cerevisiae, GI6319958, Length=293, Percent_Identity=21.8430034129693, Blast_Score=73, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24646159, Length=320, Percent_Identity=29.375, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24646155, Length=323, Percent_Identity=27.5541795665635, Blast_Score=101, Evalue=8e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YDJG_ECOLI (P77256)

Other databases:

- EMBL:   U00096
- EMBL:   AP009048
- PIR:   C64937
- RefSeq:   AP_002390.1
- RefSeq:   NP_416285.1
- ProteinModelPortal:   P77256
- SMR:   P77256
- STRING:   P77256
- EnsemblBacteria:   EBESCT00000004636
- EnsemblBacteria:   EBESCT00000017751
- GeneID:   946283
- GenomeReviews:   AP009048_GR
- GenomeReviews:   U00096_GR
- KEGG:   ecj:JW1760
- KEGG:   eco:b1771
- EchoBASE:   EB3256
- EcoGene:   EG13483
- eggNOG:   COG0667
- GeneTree:   EBGT00050000009263
- HOGENOM:   HBG605727
- OMA:   IDIYITH
- ProtClustDB:   CLSK880189
- BioCyc:   EcoCyc:G6958-MONOMER
- BioCyc:   MetaCyc:G6958-MONOMER
- Genevestigator:   P77256
- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210
- Gene3D:   G3DSA:3.20.20.100
- PANTHER:   PTHR11732
- PRINTS:   PR00069

Pfam domain/function: PF00248 Aldo_ket_red; SSF51430 Aldo/ket_red

EC number: 1.-.-.- [C]

Molecular weight: Translated: 36329; Mature: 36329

Theoretical pI: Translated: 4.88; Mature: 4.88

Prosite motif: NA

Important sites: ACT_SITE 59-59

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIPLGTTDITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILEAHRCGINLIDTAPGYN
CCCCCCCCCCEEHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCC
FGNSEVIVGQALKKLPREQVVVETKCGIVWERKGSLFNKVGDRQLYKNLSPESIREEVAA
CCCCCCHHHHHHHHCCHHHEEEEECCCEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
SLQRLGIDYIDIYMTHWQSVPPFFTPIAETVAVLNELKSEGKIRAIGAANVDADHIREYL
HHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
QYGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYSPLEQGLLTGTITRDYVPGGARA
HHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHCCCEEECCCCCCCCCCCCC
NKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLALAWILKQSDLISILSGATAPEQVRE
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHC
NVAALNINLSDADATLMREMAEALER
CHHEEEEECCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKKIPLGTTDITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILEAHRCGINLIDTAPGYN
CCCCCCCCCCEEHHHCCCCEEECCCCCCCCCCCCHHHHHHHHHHHHHCCCEEEECCCCCC
FGNSEVIVGQALKKLPREQVVVETKCGIVWERKGSLFNKVGDRQLYKNLSPESIREEVAA
CCCCCCHHHHHHHHCCHHHEEEEECCCEEECCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
SLQRLGIDYIDIYMTHWQSVPPFFTPIAETVAVLNELKSEGKIRAIGAANVDADHIREYL
HHHHHCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHH
QYGELDIIQAKYSILDRAMENELLPLCRDNGIVVQVYSPLEQGLLTGTITRDYVPGGARA
HHCCCHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECHHHCCCEEECCCCCCCCCCCCC
NKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLALAWILKQSDLISILSGATAPEQVRE
CHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHC
NVAALNINLSDADATLMREMAEALER
CHHEEEEECCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503