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The map label for this gene is iolE [H]

Identifier: 218688153

GI number: 218688153

Start: 321325

End: 322245

Strand: Direct

Name: iolE [H]

Synonym: ECED1_0303

Alternate gene names: 218688153

Gene position: 321325-322245 (Clockwise)

Preceding gene: 218688152

Following gene: 218688154

Centisome position: 6.17

GC content: 42.56

Gene sequence:

>921_bases
GTGGGAGCCAGCAACATGTACAATGTAAAAAAGAGCATTAAGTTGGGGATTGCGCCTATCGGTTGGCGCAATGATGATAT
TCCTGAGATTGGTAAAGAAAATACATATAAACAAATACTTAGTGATGCCGCGCTCACCGGTTTTTCCGGGACGGAAGTTG
GCGGTTGTTATCCGCAGGATCCTGCTGAGTTAAATAAAGAGTTAATGCTTCGCGGCCTGGAAATACCAGGCCAGTGGTTT
TCTTCCTTTATTATTCGCGATGGTATTGCATCTGCGATGAATGCTTTTGAACAGCATTGTGCTTATTTGCAGGCAATACA
TGCATATGTCGCCGTTGTTTCTGAACAAACTTATAGTATTCAAGGTATTATCGATAAGTGCGTTTATACAGAGAAGCCTA
ACTTCAGCGACAGTGAATGGCAGCTTTTATGCGAAGGACTTAATGCGCTTGGGAAGATTGCCAATGCGCACGGGCTGAAG
CTCGCTTTCCATCATCATATGGGTACCGGTGTGCAGACTCTGCCGGAAGTGGATCGACTCATGGAGAATACCGATCCGCA
ATTTGTACATCTGCTGTTTGATACCGGGCATATATATGTTTCTGACGGCGATGTCATGCCGCTACTGAGTAAACATTTTG
ATCGTATTAAACACGTTCATTTTAAAGATGTGCGTAATGAAAAACTCAAAGCATGTCGCCTCGCGAAGAAATCATTCCTC
AATTCTTTCCTTGATGGTGTGTTTACCGTCCCCGGCGATGGAAATATTGATTTTAAATCCGTATTAGCTTATCTGGTCGG
GCATCAATATTCTGGCTGGATTGTTGTTGAGGCCGAGCAGGATCCTAAGAAATATAACCCATTGGAATATGCGCAAAAAG
GTAAAAAGCATATTGATGAGTTACTGAAAAATTATCTTTAA

Upstream 100 bases:

>100_bases
TTCAACCAGGATAGATAAAGTTTTTCAGGCTACAAAAAGTAATATGTTGTCCATCAAAGGTTAATTCGCATCGCGGTATG
CAGTAAAAGCGTTTCATTAA

Downstream 100 bases:

>100_bases
TTGAAAAGGAAACAGAAAATGACTTTAAAAGCAGGTATTGTAGGTATCGGCATGATCGGCTCCGATCACTTAAGACGTCT
GGCCAACACCGTGTCGGGTG

Product: 2-keto-myo-inositol dehydratase

Products: NA

Alternate protein names: 2-keto-myo-inositol dehydratase; 2KMI dehydratase [H]

Number of amino acids: Translated: 306; Mature: 305

Protein sequence:

>306_residues
MGASNMYNVKKSIKLGIAPIGWRNDDIPEIGKENTYKQILSDAALTGFSGTEVGGCYPQDPAELNKELMLRGLEIPGQWF
SSFIIRDGIASAMNAFEQHCAYLQAIHAYVAVVSEQTYSIQGIIDKCVYTEKPNFSDSEWQLLCEGLNALGKIANAHGLK
LAFHHHMGTGVQTLPEVDRLMENTDPQFVHLLFDTGHIYVSDGDVMPLLSKHFDRIKHVHFKDVRNEKLKACRLAKKSFL
NSFLDGVFTVPGDGNIDFKSVLAYLVGHQYSGWIVVEAEQDPKKYNPLEYAQKGKKHIDELLKNYL

Sequences:

>Translated_306_residues
MGASNMYNVKKSIKLGIAPIGWRNDDIPEIGKENTYKQILSDAALTGFSGTEVGGCYPQDPAELNKELMLRGLEIPGQWF
SSFIIRDGIASAMNAFEQHCAYLQAIHAYVAVVSEQTYSIQGIIDKCVYTEKPNFSDSEWQLLCEGLNALGKIANAHGLK
LAFHHHMGTGVQTLPEVDRLMENTDPQFVHLLFDTGHIYVSDGDVMPLLSKHFDRIKHVHFKDVRNEKLKACRLAKKSFL
NSFLDGVFTVPGDGNIDFKSVLAYLVGHQYSGWIVVEAEQDPKKYNPLEYAQKGKKHIDELLKNYL
>Mature_305_residues
GASNMYNVKKSIKLGIAPIGWRNDDIPEIGKENTYKQILSDAALTGFSGTEVGGCYPQDPAELNKELMLRGLEIPGQWFS
SFIIRDGIASAMNAFEQHCAYLQAIHAYVAVVSEQTYSIQGIIDKCVYTEKPNFSDSEWQLLCEGLNALGKIANAHGLKL
AFHHHMGTGVQTLPEVDRLMENTDPQFVHLLFDTGHIYVSDGDVMPLLSKHFDRIKHVHFKDVRNEKLKACRLAKKSFLN
SFLDGVFTVPGDGNIDFKSVLAYLVGHQYSGWIVVEAEQDPKKYNPLEYAQKGKKHIDELLKNYL

Specific function: Catalyzes the dehydration of inosose (2-keto-myo- inositol, 2KMI or 2,4,6/3,5-pentahydroxycyclohexanone) to 3D- (3,5/4)-trihydroxycyclohexane-1,2-dione (D-2,3-diketo-4-deoxy-epi- inositol) [H]

COG id: COG1082

COG function: function code G; Sugar phosphate isomerases/epimerases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iolE/mocC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013022
- InterPro:   IPR012307 [H]

Pfam domain/function: PF01261 AP_endonuc_2 [H]

EC number: =4.2.1.44 [H]

Molecular weight: Translated: 34337; Mature: 34205

Theoretical pI: Translated: 6.57; Mature: 6.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGASNMYNVKKSIKLGIAPIGWRNDDIPEIGKENTYKQILSDAALTGFSGTEVGGCYPQD
CCCCCHHHHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
PAELNKELMLRGLEIPGQWFSSFIIRDGIASAMNAFEQHCAYLQAIHAYVAVVSEQTYSI
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
QGIIDKCVYTEKPNFSDSEWQLLCEGLNALGKIANAHGLKLAFHHHMGTGVQTLPEVDRL
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHCCCCHHHHHHHHHH
MENTDPQFVHLLFDTGHIYVSDGDVMPLLSKHFDRIKHVHFKDVRNEKLKACRLAKKSFL
HHCCCCCEEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSFLDGVFTVPGDGNIDFKSVLAYLVGHQYSGWIVVEAEQDPKKYNPLEYAQKGKKHIDE
HHHHHCEEECCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
LLKNYL
HHHHCC
>Mature Secondary Structure 
GASNMYNVKKSIKLGIAPIGWRNDDIPEIGKENTYKQILSDAALTGFSGTEVGGCYPQD
CCCCHHHHHHHHEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
PAELNKELMLRGLEIPGQWFSSFIIRDGIASAMNAFEQHCAYLQAIHAYVAVVSEQTYSI
HHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
QGIIDKCVYTEKPNFSDSEWQLLCEGLNALGKIANAHGLKLAFHHHMGTGVQTLPEVDRL
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEHHCCCCHHHHHHHHHH
MENTDPQFVHLLFDTGHIYVSDGDVMPLLSKHFDRIKHVHFKDVRNEKLKACRLAKKSFL
HHCCCCCEEEEEEECCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NSFLDGVFTVPGDGNIDFKSVLAYLVGHQYSGWIVVEAEQDPKKYNPLEYAQKGKKHIDE
HHHHHCEEECCCCCCCCHHHHHHHHHCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHH
LLKNYL
HHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA