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The map label for this gene is iolG [H]

Identifier: 218688154

GI number: 218688154

Start: 322246

End: 323274

Strand: Direct

Name: iolG [H]

Synonym: ECED1_0304

Alternate gene names: 218688154

Gene position: 322246-323274 (Clockwise)

Preceding gene: 218688153

Following gene: 218688155

Centisome position: 6.19

GC content: 48.49

Gene sequence:

>1029_bases
TTGAAAAGGAAACAGAAAATGACTTTAAAAGCAGGTATTGTAGGTATCGGCATGATCGGCTCCGATCACTTAAGACGTCT
GGCCAACACCGTGTCGGGTGTAGAGGTTGTTGCCGTATGTGATATCGTCGCGGGTAGGGCGCAGGCGGCGCTGGATAAGT
ATGCGATCGAAGCCAAAGATTATAATGACTATCACGATCTGATTAATGATAAAGACGTTGAAGTGGTCATCATTACCGCA
TCAAATGAGGCGCACGCCGATGTGGCCGTTGCCGCGCTAAATGCTAACAAATATGTTTTCTGCGAAAAACCGTTAGCGGT
GACGGCTGCGGATTGTCAGCGTGTGATTGAAGCAGAGCAGAAAAATGGTAAGCGCATGGTGCAGATTGGTTTTATGCGCC
GCTACGACAAAGGTTACGTTCAGCTGAAAAATATTATCGACAGCGGCGAAATCGGTCAGCCATTAATGGTTCATGGACGT
CATTACAATGCCAGCACGGTGCCAGAATACAAAACGCCACAGGCTATCTATGAAACATTGATTCATGAAATTGACATTAT
GCACTGGCTGCTTAACGAAGATTATAAAACCGTTAAGGTTTACTTCCCGCGTCAGTCCAGCCTGGTGACCACTCTGCGTG
ATCCGCAGCTGGTTGTAATGGAAACCACCTCCGGCATCAATATTGTGGTTGAAGTATTTGTGAACTGCCAGTATGGCTAC
GACATTCACTGCGATGTTACCGGCGAGAAAGGAATGGCGGAGCTGCCAACCGTCGCCAGCGCTGCGGTACGGAAAGCGGC
GAAGTATAGCACCGACATCCTGGTTGACTGGAAACAGCGCTTTATTGATGCCTACGACATTGAGTTCCAGGATTTCTTCG
ATCGCCTGAACGCAGGATTGCCGCCAGCAGGCCCAACGTCATGGGATGGTTATCTGGCTGCGGTTACCGCTGATGCCTGC
GTGAAGTCTCAGGAAACAGGGAATACCGAGATTGTTGAATTACCCTCAAAACCTGATTTCTACAAATAA

Upstream 100 bases:

>100_bases
TGTTGTTGAGGCCGAGCAGGATCCTAAGAAATATAACCCATTGGAATATGCGCAAAAAGGTAAAAAGCATATTGATGAGT
TACTGAAAAATTATCTTTAA

Downstream 100 bases:

>100_bases
ACCTTCCGCGTATTAAAACCTTCTGCCGGATAGCGATGCTTAAGCGTCCTATCCGGCATATCACAATTTATTATCTTCTT
TTATCCGGAACTTCCCTATG

Product: inositol 2-dehydrogenase

Products: NA

Alternate protein names: Myo-inositol 2-dehydrogenase; MI 2-dehydrogenase [H]

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MKRKQKMTLKAGIVGIGMIGSDHLRRLANTVSGVEVVAVCDIVAGRAQAALDKYAIEAKDYNDYHDLINDKDVEVVIITA
SNEAHADVAVAALNANKYVFCEKPLAVTAADCQRVIEAEQKNGKRMVQIGFMRRYDKGYVQLKNIIDSGEIGQPLMVHGR
HYNASTVPEYKTPQAIYETLIHEIDIMHWLLNEDYKTVKVYFPRQSSLVTTLRDPQLVVMETTSGINIVVEVFVNCQYGY
DIHCDVTGEKGMAELPTVASAAVRKAAKYSTDILVDWKQRFIDAYDIEFQDFFDRLNAGLPPAGPTSWDGYLAAVTADAC
VKSQETGNTEIVELPSKPDFYK

Sequences:

>Translated_342_residues
MKRKQKMTLKAGIVGIGMIGSDHLRRLANTVSGVEVVAVCDIVAGRAQAALDKYAIEAKDYNDYHDLINDKDVEVVIITA
SNEAHADVAVAALNANKYVFCEKPLAVTAADCQRVIEAEQKNGKRMVQIGFMRRYDKGYVQLKNIIDSGEIGQPLMVHGR
HYNASTVPEYKTPQAIYETLIHEIDIMHWLLNEDYKTVKVYFPRQSSLVTTLRDPQLVVMETTSGINIVVEVFVNCQYGY
DIHCDVTGEKGMAELPTVASAAVRKAAKYSTDILVDWKQRFIDAYDIEFQDFFDRLNAGLPPAGPTSWDGYLAAVTADAC
VKSQETGNTEIVELPSKPDFYK
>Mature_342_residues
MKRKQKMTLKAGIVGIGMIGSDHLRRLANTVSGVEVVAVCDIVAGRAQAALDKYAIEAKDYNDYHDLINDKDVEVVIITA
SNEAHADVAVAALNANKYVFCEKPLAVTAADCQRVIEAEQKNGKRMVQIGFMRRYDKGYVQLKNIIDSGEIGQPLMVHGR
HYNASTVPEYKTPQAIYETLIHEIDIMHWLLNEDYKTVKVYFPRQSSLVTTLRDPQLVVMETTSGINIVVEVFVNCQYGY
DIHCDVTGEKGMAELPTVASAAVRKAAKYSTDILVDWKQRFIDAYDIEFQDFFDRLNAGLPPAGPTSWDGYLAAVTADAC
VKSQETGNTEIVELPSKPDFYK

Specific function: Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) [H]

COG id: COG0673

COG function: function code R; Predicted dehydrogenases and related proteins

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gfo/idh/mocA family [H]

Homologues:

Organism=Escherichia coli, GI87082405, Length=196, Percent_Identity=26.0204081632653, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787574, Length=170, Percent_Identity=27.6470588235294, Blast_Score=62, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24581117, Length=146, Percent_Identity=33.5616438356164, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016040
- InterPro:   IPR000683
- InterPro:   IPR004104 [H]

Pfam domain/function: PF01408 GFO_IDH_MocA; PF02894 GFO_IDH_MocA_C [H]

EC number: =1.1.1.18 [H]

Molecular weight: Translated: 38082; Mature: 38082

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRKQKMTLKAGIVGIGMIGSDHLRRLANTVSGVEVVAVCDIVAGRAQAALDKYAIEAKD
CCCCCCEEEEECEEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHEEECCC
YNDYHDLINDKDVEVVIITASNEAHADVAVAALNANKYVFCEKPLAVTAADCQRVIEAEQ
CCCHHHHCCCCCEEEEEEEECCCCCCEEEEEEECCCEEEEECCCCEEEHHHHHHHHHHHH
KNGKRMVQIGFMRRYDKGYVQLKNIIDSGEIGQPLMVHGRHYNASTVPEYKTPQAIYETL
CCCCEEEEEHHHHHCCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHH
IHEIDIMHWLLNEDYKTVKVYFPRQSSLVTTLRDPQLVVMETTSGINIVVEVFVNCQYGY
HHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCEEEEEEECCCCEEEEEEEEEEECCC
DIHCDVTGEKGMAELPTVASAAVRKAAKYSTDILVDWKQRFIDAYDIEFQDFFDRLNAGL
EEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHCCHHCCCCHHHHHHHHCCCC
PPAGPTSWDGYLAAVTADACVKSQETGNTEIVELPSKPDFYK
CCCCCCCCCCEEEEEEHHHHHCCCCCCCEEEEECCCCCCCCC
>Mature Secondary Structure
MKRKQKMTLKAGIVGIGMIGSDHLRRLANTVSGVEVVAVCDIVAGRAQAALDKYAIEAKD
CCCCCCEEEEECEEEEEECCHHHHHHHHHHHCCHHHHHHHHHHHCHHHHHHHHHEEECCC
YNDYHDLINDKDVEVVIITASNEAHADVAVAALNANKYVFCEKPLAVTAADCQRVIEAEQ
CCCHHHHCCCCCEEEEEEEECCCCCCEEEEEEECCCEEEEECCCCEEEHHHHHHHHHHHH
KNGKRMVQIGFMRRYDKGYVQLKNIIDSGEIGQPLMVHGRHYNASTVPEYKTPQAIYETL
CCCCEEEEEHHHHHCCCCHHHHHHHHCCCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHH
IHEIDIMHWLLNEDYKTVKVYFPRQSSLVTTLRDPQLVVMETTSGINIVVEVFVNCQYGY
HHHHHHHHHHHCCCCEEEEEEECCCCCEEEEECCCEEEEEEECCCCEEEEEEEEEEECCC
DIHCDVTGEKGMAELPTVASAAVRKAAKYSTDILVDWKQRFIDAYDIEFQDFFDRLNAGL
EEEEEECCCCCCCCCCHHHHHHHHHHHHCCCCEEEEHHHHCCHHCCCCHHHHHHHHCCCC
PPAGPTSWDGYLAAVTADACVKSQETGNTEIVELPSKPDFYK
CCCCCCCCCCEEEEEEHHHHHCCCCCCCEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA