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The map label for this gene is trkG [H]

Identifier: 218549289

GI number: 218549289

Start: 1998187

End: 1999662

Strand: Direct

Name: trkG [H]

Synonym: EFER_1950

Alternate gene names: 218549289

Gene position: 1998187-1999662 (Clockwise)

Preceding gene: 218549288

Following gene: 218549290

Centisome position: 43.55

GC content: 42.48

Gene sequence:

>1476_bases
TTGATAGGCCATTCATCTATGAATACATCTCATTTGCGAGTTGTCACTCATATGTGCGGTTTTTTGGTCTGGCTTTATAG
CTTATCTATGTTGCCACCGATGCTTATCGCCTTGATCTACAAGGAAAGAAGCTTTTTCGTTTTCCTCGAAACATTTCTGG
TATTTTTTAGCCTTGGAGGCATTGCCTGGCTGGCGACAAAGAAAGCGGGGATTCAACTGCGCACCAGGGATGGTTTTCTG
ATCATTGTGCTGTTCTGGATCTTATTTTCCATTATCAGTGCATTTCCTTTGTGGATTGATGATGAGTTTAACTTAAGTTT
TGTTGATGCTTTATTCGAAGGTGTTTCCGGGATCACAACTACCGGTGCCACTGTCATTTCCGATGTGAGCACTTTACCTT
TTGCTTTTCTATACTATCGCGCACAACTGAACTTTATCGGCGGCTTAGGCGTCATCGTTCTCGCGGTTGCTGTACTACCT
TTATTAGGCATTGGTGGCGCAAAACTCTATCAATCTGAAATGCCGGGGCCGTTTAAAGATGACAAACTGACTCCTCGCCT
GGCAGATACATCTCGTACACTTTGGCTGACTTATCTTTTGCTCGGCATAGTATGCAGCGCATCATATTTTGTTGCAGGTA
TGCCGTTGTTTGACGCTATTTGCCACGGTATATCGACAGTTTCTTTAGGCGGCTTTTCAACACATAGTGAAAGCATTGGT
TTTTATAACAGCCATGCCATTGAGTTTGTTGCCGGACTGTTTTCATTGCTCTCTGCGATTAATTTTACCTTGTGGTATGT
GGTCATCGTTAAGCGTCAGTTCAGACCTTTACTACGTAACAGTGAATTGCACTTTTTCCTGCTTGTCGCCTTTATAGTCA
TTGCGATTACGGCATGGCAAGTCTGGCATGCGGGAATGTATGATATCTCTTCCAGCATTATTCATGCCTTTTTTCTCACC
AGTTCGATGATGACAGATAATGGTCTGGCAACTCTGGATTACGCAAACTGGCCTTCTCACACCATTATTTTCTTAATGCT
GTTGAGTTTTTTTGGTGGTTGTATCGGTTCAACTTGTGGTGGCATTAAGGCGTTACGTTTTCTCATTTTATTTAAACAGA
GCAGAAATGAGCTGCACCAGTTAGCTCATCCCAGAGCATTACTGAGTATCAAAGTCGACGGCAATGTCGTTACGGACCGT
GTCCTGCGCTCGGTATGGAGCTTTTTCTTTCTCTATATTCTGTTTACGGTATTTTTTATCTGCATATTAAACATGATGGG
CTATGATCTATTAACGTCATTCGCTACCGTCGCGGCATGCATTAATAACATGGGGCTTGGATTTGGCGAAACTGCATCGA
CATTTGGTACATTAAATGATGCAGCAAAATATCTTATGTGCACAGCGATGATTCTGGGCCGACTGGAAATTTATCCGGTA
TTAATACTGTTTTCACGATTTTTCTGGAAATCCTGA

Upstream 100 bases:

>100_bases
ACGAAAGGTAATCGTGAGCGAGTTTAAGCGCAGCACATGCAACTTGAAGTATGGCGAGTATAATAGCCGCCAAACTGAAG
GCATAACACTGGAGGTATAA

Downstream 100 bases:

>100_bases
TATACCACTTTGGATAGATTGACAGCATTTTTGGGTGTTGGTAGAAATAGCGCCAACTCAGTCGCGAAGATAGTGACTAA
TATCCCTGAGAAGTAATAGG

Product: Trk system potassium uptake protein

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 491

Protein sequence:

>491_residues
MIGHSSMNTSHLRVVTHMCGFLVWLYSLSMLPPMLIALIYKERSFFVFLETFLVFFSLGGIAWLATKKAGIQLRTRDGFL
IIVLFWILFSIISAFPLWIDDEFNLSFVDALFEGVSGITTTGATVISDVSTLPFAFLYYRAQLNFIGGLGVIVLAVAVLP
LLGIGGAKLYQSEMPGPFKDDKLTPRLADTSRTLWLTYLLLGIVCSASYFVAGMPLFDAICHGISTVSLGGFSTHSESIG
FYNSHAIEFVAGLFSLLSAINFTLWYVVIVKRQFRPLLRNSELHFFLLVAFIVIAITAWQVWHAGMYDISSSIIHAFFLT
SSMMTDNGLATLDYANWPSHTIIFLMLLSFFGGCIGSTCGGIKALRFLILFKQSRNELHQLAHPRALLSIKVDGNVVTDR
VLRSVWSFFFLYILFTVFFICILNMMGYDLLTSFATVAACINNMGLGFGETASTFGTLNDAAKYLMCTAMILGRLEIYPV
LILFSRFFWKS

Sequences:

>Translated_491_residues
MIGHSSMNTSHLRVVTHMCGFLVWLYSLSMLPPMLIALIYKERSFFVFLETFLVFFSLGGIAWLATKKAGIQLRTRDGFL
IIVLFWILFSIISAFPLWIDDEFNLSFVDALFEGVSGITTTGATVISDVSTLPFAFLYYRAQLNFIGGLGVIVLAVAVLP
LLGIGGAKLYQSEMPGPFKDDKLTPRLADTSRTLWLTYLLLGIVCSASYFVAGMPLFDAICHGISTVSLGGFSTHSESIG
FYNSHAIEFVAGLFSLLSAINFTLWYVVIVKRQFRPLLRNSELHFFLLVAFIVIAITAWQVWHAGMYDISSSIIHAFFLT
SSMMTDNGLATLDYANWPSHTIIFLMLLSFFGGCIGSTCGGIKALRFLILFKQSRNELHQLAHPRALLSIKVDGNVVTDR
VLRSVWSFFFLYILFTVFFICILNMMGYDLLTSFATVAACINNMGLGFGETASTFGTLNDAAKYLMCTAMILGRLEIYPV
LILFSRFFWKS
>Mature_491_residues
MIGHSSMNTSHLRVVTHMCGFLVWLYSLSMLPPMLIALIYKERSFFVFLETFLVFFSLGGIAWLATKKAGIQLRTRDGFL
IIVLFWILFSIISAFPLWIDDEFNLSFVDALFEGVSGITTTGATVISDVSTLPFAFLYYRAQLNFIGGLGVIVLAVAVLP
LLGIGGAKLYQSEMPGPFKDDKLTPRLADTSRTLWLTYLLLGIVCSASYFVAGMPLFDAICHGISTVSLGGFSTHSESIG
FYNSHAIEFVAGLFSLLSAINFTLWYVVIVKRQFRPLLRNSELHFFLLVAFIVIAITAWQVWHAGMYDISSSIIHAFFLT
SSMMTDNGLATLDYANWPSHTIIFLMLLSFFGGCIGSTCGGIKALRFLILFKQSRNELHQLAHPRALLSIKVDGNVVTDR
VLRSVWSFFFLYILFTVFFICILNMMGYDLLTSFATVAACINNMGLGFGETASTFGTLNDAAKYLMCTAMILGRLEIYPV
LILFSRFFWKS

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA. TrkE increases the affinity of the system [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI1787626, Length=485, Percent_Identity=78.7628865979381, Blast_Score=780, Evalue=0.0,
Organism=Escherichia coli, GI48994987, Length=484, Percent_Identity=41.5289256198347, Blast_Score=362, Evalue=1e-101,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 54781; Mature: 54781

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGHSSMNTSHLRVVTHMCGFLVWLYSLSMLPPMLIALIYKERSFFVFLETFLVFFSLGG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
IAWLATKKAGIQLRTRDGFLIIVLFWILFSIISAFPLWIDDEFNLSFVDALFEGVSGITT
HHEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHCCCCCCC
TGATVISDVSTLPFAFLYYRAQLNFIGGLGVIVLAVAVLPLLGIGGAKLYQSEMPGPFKD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCC
DKLTPRLADTSRTLWLTYLLLGIVCSASYFVAGMPLFDAICHGISTVSLGGFSTHSESIG
CCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEECCCCCCCCCCCC
FYNSHAIEFVAGLFSLLSAINFTLWYVVIVKRQFRPLLRNSELHFFLLVAFIVIAITAWQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VWHAGMYDISSSIIHAFFLTSSMMTDNGLATLDYANWPSHTIIFLMLLSFFGGCIGSTCG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCH
GIKALRFLILFKQSRNELHQLAHPRALLSIKVDGNVVTDRVLRSVWSFFFLYILFTVFFI
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
CILNMMGYDLLTSFATVAACINNMGLGFGETASTFGTLNDAAKYLMCTAMILGRLEIYPV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
LILFSRFFWKS
HHHHHHHHHCC
>Mature Secondary Structure
MIGHSSMNTSHLRVVTHMCGFLVWLYSLSMLPPMLIALIYKERSFFVFLETFLVFFSLGG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCC
IAWLATKKAGIQLRTRDGFLIIVLFWILFSIISAFPLWIDDEFNLSFVDALFEGVSGITT
HHEEEECCCCEEEEECCCHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHCCCCCCC
TGATVISDVSTLPFAFLYYRAQLNFIGGLGVIVLAVAVLPLLGIGGAKLYQSEMPGPFKD
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCC
DKLTPRLADTSRTLWLTYLLLGIVCSASYFVAGMPLFDAICHGISTVSLGGFSTHSESIG
CCCCCCHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEECCCCCCCCCCCC
FYNSHAIEFVAGLFSLLSAINFTLWYVVIVKRQFRPLLRNSELHFFLLVAFIVIAITAWQ
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VWHAGMYDISSSIIHAFFLTSSMMTDNGLATLDYANWPSHTIIFLMLLSFFGGCIGSTCG
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCCH
GIKALRFLILFKQSRNELHQLAHPRALLSIKVDGNVVTDRVLRSVWSFFFLYILFTVFFI
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHH
CILNMMGYDLLTSFATVAACINNMGLGFGETASTFGTLNDAAKYLMCTAMILGRLEIYPV
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCHHHHHHHHHHHHHHHHHHHHHHH
LILFSRFFWKS
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2022616; 9097039; 9278503 [H]