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The map label for this gene is yvmA [H]

Identifier: 218233100

GI number: 218233100

Start: 776505

End: 777689

Strand: Reverse

Name: yvmA [H]

Synonym: BCB4264_A0801

Alternate gene names: 218233100

Gene position: 777689-776505 (Counterclockwise)

Preceding gene: 218235926

Following gene: 218232789

Centisome position: 14.35

GC content: 32.83

Gene sequence:

>1185_bases
ATGATGAAAAACTCTAAACTAACTTTTATTTTATATGTTGTCTGTATTAGTGCCTTATTCGGTTCCTTCGCGCAAAATAT
TTACACACCTATCTTACCGATGATTCAAAATTCTTTTCACACTTCTCTTTATCTTGTAAATATAACCGTTTCACTTTTCA
CATTCGTTCTTGCAATTATGCAGCTCGTATATGGACCTTTAATTGATACAAAAGGAAGAAAATCTGTCCTTATTCCTAGT
TTGGTCATTAGTACAATTGGTTCAATCGGATGTGCTTTTTCGGCAAACATTTATTTATTTCTCTTTTTTAGAGCTGTTCA
AGCTATAGGAATAGCGGCTATACCTGTAGTTTCAGCAACGATTATCGGCGATTTATTTGAAGGAAAAGAACGCGGAGAAG
CGATGAGCCTATACCAAATGTTACTTGCCCTCGCACCTGCAATGGCTCCTCTCATAGGTGGTTATCTTGGCAGTATACAT
GGTCACTTATCTGTATTTCTCTTTTTATCTACACTTGGCATTATCTTATTAATTATAAACATTTCACTACTCCCAGAAAC
AAAGCCAAATATAATTAAACAAGCTAAAGCACAAAAGAATTACTCTCTTATCTTAAAAAATAAAACTGGATTTTCTATTA
CTCTTATTGGCTTCATTCAATTTTGTATTTACTTTTGCTTTCTCGTTTTTTTACCGAGTATTTTAACAAATTCATTTCAT
TTAACTGTAAATAAAATTGGTCTTATGTTTGTACCAATGTCTCTTTCTATCATGCTAGGAAGTTTTTGCTACAAATTTTT
GCAAAAACGCCTCACAACAAAGCAAGCTTTATTTATTACGAGTTTCTTCAATATTATATGTGTCGTTTTATTCTCTTTCA
TATATAACATCAATATCCCATTCATCATTATCGTTACATCTTTGTACGGTTTTAGTATGGGACTTTCTATGCCAACTCAC
ACCACTTTATTAACAGAAGAATTCGTACAAGAACGCGCAACAGCTATCGGTATGTACAACTTCATCCGCTATCTTGGTAT
GGGCACAGGGCCACTTATAGGTGGATTTCTTTTATTTAACCAAAATTACTTTTGGATTTTCTTCCTAGGCGCAATTATGT
TTTTACTTGTAATCTTATATACAATGAAAATGCTAAGCCTTCATGCTGTACAAAAATTAAAATAG

Upstream 100 bases:

>100_bases
CTATATACCATTTTAAAACCATTTTTTCATCTTTACAAGTAAGAAAATCATGTTAAAATAAATTTAGTTTCCAAGGAAAC
TAATTCACAAGGAGGTTAAC

Downstream 100 bases:

>100_bases
AGCCCCAAAAATGTCGGCTCTATTTTACCCTCTTTGATCCGCAACAATATGAATATCAATATACTTTGTTTGTCTCATAA
TTTCATTTACAATAGAACCT

Product: major facilitator family transporter

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MMKNSKLTFILYVVCISALFGSFAQNIYTPILPMIQNSFHTSLYLVNITVSLFTFVLAIMQLVYGPLIDTKGRKSVLIPS
LVISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVSATIIGDLFEGKERGEAMSLYQMLLALAPAMAPLIGGYLGSIH
GHLSVFLFLSTLGIILLIINISLLPETKPNIIKQAKAQKNYSLILKNKTGFSITLIGFIQFCIYFCFLVFLPSILTNSFH
LTVNKIGLMFVPMSLSIMLGSFCYKFLQKRLTTKQALFITSFFNIICVVLFSFIYNINIPFIIIVTSLYGFSMGLSMPTH
TTLLTEEFVQERATAIGMYNFIRYLGMGTGPLIGGFLLFNQNYFWIFFLGAIMFLLVILYTMKMLSLHAVQKLK

Sequences:

>Translated_394_residues
MMKNSKLTFILYVVCISALFGSFAQNIYTPILPMIQNSFHTSLYLVNITVSLFTFVLAIMQLVYGPLIDTKGRKSVLIPS
LVISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVSATIIGDLFEGKERGEAMSLYQMLLALAPAMAPLIGGYLGSIH
GHLSVFLFLSTLGIILLIINISLLPETKPNIIKQAKAQKNYSLILKNKTGFSITLIGFIQFCIYFCFLVFLPSILTNSFH
LTVNKIGLMFVPMSLSIMLGSFCYKFLQKRLTTKQALFITSFFNIICVVLFSFIYNINIPFIIIVTSLYGFSMGLSMPTH
TTLLTEEFVQERATAIGMYNFIRYLGMGTGPLIGGFLLFNQNYFWIFFLGAIMFLLVILYTMKMLSLHAVQKLK
>Mature_394_residues
MMKNSKLTFILYVVCISALFGSFAQNIYTPILPMIQNSFHTSLYLVNITVSLFTFVLAIMQLVYGPLIDTKGRKSVLIPS
LVISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVSATIIGDLFEGKERGEAMSLYQMLLALAPAMAPLIGGYLGSIH
GHLSVFLFLSTLGIILLIINISLLPETKPNIIKQAKAQKNYSLILKNKTGFSITLIGFIQFCIYFCFLVFLPSILTNSFH
LTVNKIGLMFVPMSLSIMLGSFCYKFLQKRLTTKQALFITSFFNIICVVLFSFIYNINIPFIIIVTSLYGFSMGLSMPTH
TTLLTEEFVQERATAIGMYNFIRYLGMGTGPLIGGFLLFNQNYFWIFFLGAIMFLLVILYTMKMLSLHAVQKLK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. TCR/tet family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=262, Percent_Identity=29.3893129770992, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1790146, Length=183, Percent_Identity=26.775956284153, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI87082312, Length=340, Percent_Identity=23.5294117647059, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788509, Length=245, Percent_Identity=24.4897959183673, Blast_Score=67, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6322071, Length=292, Percent_Identity=26.027397260274, Blast_Score=87, Evalue=5e-18,
Organism=Saccharomyces cerevisiae, GI6322070, Length=283, Percent_Identity=26.8551236749117, Blast_Score=79, Evalue=2e-15,
Organism=Saccharomyces cerevisiae, GI6324264, Length=179, Percent_Identity=27.9329608938547, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319517, Length=202, Percent_Identity=28.7128712871287, Blast_Score=73, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6319657, Length=165, Percent_Identity=32.7272727272727, Blast_Score=71, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001411 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43971; Mature: 43971

Theoretical pI: Translated: 9.90; Mature: 9.90

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMKNSKLTFILYVVCISALFGSFAQNIYTPILPMIQNSFHTSLYLVNITVSLFTFVLAIM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEEHHHHHHHHHHHHHH
QLVYGPLIDTKGRKSVLIPSLVISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVSAT
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIGDLFEGKERGEAMSLYQMLLALAPAMAPLIGGYLGSIHGHLSVFLFLSTLGIILLIIN
HHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISLLPETKPNIIKQAKAQKNYSLILKNKTGFSITLIGFIQFCIYFCFLVFLPSILTNSFH
HHHCCCCCHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCE
LTVNKIGLMFVPMSLSIMLGSFCYKFLQKRLTTKQALFITSFFNIICVVLFSFIYNINIP
EEEEHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FIIIVTSLYGFSMGLSMPTHTTLLTEEFVQERATAIGMYNFIRYLGMGTGPLIGGFLLFN
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEC
QNYFWIFFLGAIMFLLVILYTMKMLSLHAVQKLK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MMKNSKLTFILYVVCISALFGSFAQNIYTPILPMIQNSFHTSLYLVNITVSLFTFVLAIM
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHEEEEEHHHHHHHHHHHHHH
QLVYGPLIDTKGRKSVLIPSLVISTIGSIGCAFSANIYLFLFFRAVQAIGIAAIPVVSAT
HHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IIGDLFEGKERGEAMSLYQMLLALAPAMAPLIGGYLGSIHGHLSVFLFLSTLGIILLIIN
HHHHHHCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ISLLPETKPNIIKQAKAQKNYSLILKNKTGFSITLIGFIQFCIYFCFLVFLPSILTNSFH
HHHCCCCCHHHHHHHHHCCCCEEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCE
LTVNKIGLMFVPMSLSIMLGSFCYKFLQKRLTTKQALFITSFFNIICVVLFSFIYNINIP
EEEEHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
FIIIVTSLYGFSMGLSMPTHTTLLTEEFVQERATAIGMYNFIRYLGMGTGPLIGGFLLFN
HHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHEEC
QNYFWIFFLGAIMFLLVILYTMKMLSLHAVQKLK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]