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The map label for this gene is adh [H]

Identifier: 209552126

GI number: 209552126

Start: 227563

End: 228693

Strand: Reverse

Name: adh [H]

Synonym: Rleg2_6278

Alternate gene names: 209552126

Gene position: 228693-227563 (Counterclockwise)

Preceding gene: 209552130

Following gene: 209552125

Centisome position: 74.07

GC content: 59.42

Gene sequence:

>1131_bases
ATGAACCAAATATCGGACTTGCCTACGACCATGCGCGCTGTTTTACTTACGGGTTTCGGCGGTATCGACAAATTGGAGTA
CCGCGAGGACGTGCCCGTTCCGACGCCGCGCGATGGCGAAGTCCTTATCAAGGTCGGTGCGTGCGGTATGAACAATACCG
ATATCAATACCAGGACGCGGTGGTATGGCCGTGACGTGAACACCAGCCTTTCCGAGGACTTCGGCCTGACGGGAGCCGAA
AATGTCACCGGAGCCGACACCAAGCAACAGAAAGCCTGGAAAGATGACTCGGTTGACTTTCCGCGGATCCAGGGGGCCGC
TATCGCCGGAACGATCGTCGCGATCGGGCCGTCCGTTTCCGACCGCCAAGTGGGAAACCGGGTTTTGGTCGATCCGTGCA
TCAGGGACCTGTCACTGCCGCGGCGCGCTCAACTTTCTCAATACATCGGCAAGGACGTTAACGGCGGCTTTGCCGAATAC
GCGGTAGTTCCCGCGATCAATGCGCACGTTCTCGAAACCTCCCTCAGCGACGCGGAGCTCGCGACATTTCCCACGTCCTA
CGATACGGCTGAAGAGATGTTGGTACGGGCGCGGCTGTCCGAGGGCGAAACGGTGGTCATCACCGGCGCGGCGGGAGGAG
TCGGTTCGGCGCTGATCCAGCTTTCACTGATCCGCGGGGCGCGCGTCATCGCAATTGCGGGCGAGAGCAAGGGCGAACGC
CTGCTTGCGCTGGGAGCACATCATTTCGTTGCTCGCGAGAGCGCCGATGTCCGGGGCCAGATCGAGGCGCTCGTGGGCGA
GAGAGCAGTTCACGTTGTCGCAGACGTTGTCGGTGGCGAATTCTTCCCGGACGCCCTCAAACTTCTCGGGCGCGGCGGGC
GCTTCACAACGGGAGGTGCGATTGGCGGCCCCATCCAGCCATTCGATCTCAGAGACCTTATTTACAAGGACCTCGAAATG
TACGGTATCACCAACCCATTGCCGGAAACGTTCAAGTCGGTCGTCGACTACATAGCGTCGGGACAGCTTAAGCCAATTCT
CGAAAAAGCGTATCCTCTCAAGGAGCTGCCGACAGCCCAGAGTGACATGGTCAAGCGATCACATCTCGGCAAACTGGTCA
TCATCCCGTGA

Upstream 100 bases:

>100_bases
GGCCGAGGATAGGCAGTTCGGATTCGCGCGACTCGCGCTGGATTTTGTGCGGTGATCAACGGTGATCACCGCGGATAGTA
GATGATGAGGAGTTGTCTTA

Downstream 100 bases:

>100_bases
CGACCCTCTCCGACCGAGTTAGTGGGACTGATTCCAGCGAGGCGAAGCCAAAATTCGCTTCGCCAAATAAGGCGCGATTG
CCGATCACAATTTTGACGTT

Product: alcohol dehydrogenase zinc-binding domain protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 376; Mature: 376

Protein sequence:

>376_residues
MNQISDLPTTMRAVLLTGFGGIDKLEYREDVPVPTPRDGEVLIKVGACGMNNTDINTRTRWYGRDVNTSLSEDFGLTGAE
NVTGADTKQQKAWKDDSVDFPRIQGAAIAGTIVAIGPSVSDRQVGNRVLVDPCIRDLSLPRRAQLSQYIGKDVNGGFAEY
AVVPAINAHVLETSLSDAELATFPTSYDTAEEMLVRARLSEGETVVITGAAGGVGSALIQLSLIRGARVIAIAGESKGER
LLALGAHHFVARESADVRGQIEALVGERAVHVVADVVGGEFFPDALKLLGRGGRFTTGGAIGGPIQPFDLRDLIYKDLEM
YGITNPLPETFKSVVDYIASGQLKPILEKAYPLKELPTAQSDMVKRSHLGKLVIIP

Sequences:

>Translated_376_residues
MNQISDLPTTMRAVLLTGFGGIDKLEYREDVPVPTPRDGEVLIKVGACGMNNTDINTRTRWYGRDVNTSLSEDFGLTGAE
NVTGADTKQQKAWKDDSVDFPRIQGAAIAGTIVAIGPSVSDRQVGNRVLVDPCIRDLSLPRRAQLSQYIGKDVNGGFAEY
AVVPAINAHVLETSLSDAELATFPTSYDTAEEMLVRARLSEGETVVITGAAGGVGSALIQLSLIRGARVIAIAGESKGER
LLALGAHHFVARESADVRGQIEALVGERAVHVVADVVGGEFFPDALKLLGRGGRFTTGGAIGGPIQPFDLRDLIYKDLEM
YGITNPLPETFKSVVDYIASGQLKPILEKAYPLKELPTAQSDMVKRSHLGKLVIIP
>Mature_376_residues
MNQISDLPTTMRAVLLTGFGGIDKLEYREDVPVPTPRDGEVLIKVGACGMNNTDINTRTRWYGRDVNTSLSEDFGLTGAE
NVTGADTKQQKAWKDDSVDFPRIQGAAIAGTIVAIGPSVSDRQVGNRVLVDPCIRDLSLPRRAQLSQYIGKDVNGGFAEY
AVVPAINAHVLETSLSDAELATFPTSYDTAEEMLVRARLSEGETVVITGAAGGVGSALIQLSLIRGARVIAIAGESKGER
LLALGAHHFVARESADVRGQIEALVGERAVHVVADVVGGEFFPDALKLLGRGGRFTTGGAIGGPIQPFDLRDLIYKDLEM
YGITNPLPETFKSVVDYIASGQLKPILEKAYPLKELPTAQSDMVKRSHLGKLVIIP

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI194239674, Length=375, Percent_Identity=27.4666666666667, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI13236495, Length=375, Percent_Identity=27.4666666666667, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI194239676, Length=374, Percent_Identity=25.9358288770053, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI18379349, Length=395, Percent_Identity=23.7974683544304, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI22538446, Length=384, Percent_Identity=24.4791666666667, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI22538444, Length=384, Percent_Identity=24.4791666666667, Blast_Score=77, Evalue=3e-14,
Organism=Homo sapiens, GI197927207, Length=193, Percent_Identity=27.4611398963731, Blast_Score=74, Evalue=2e-13,
Organism=Escherichia coli, GI226510992, Length=361, Percent_Identity=25.7617728531856, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71988145, Length=235, Percent_Identity=26.8085106382979, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17562582, Length=268, Percent_Identity=28.7313432835821, Blast_Score=73, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562584, Length=368, Percent_Identity=26.0869565217391, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6319520, Length=383, Percent_Identity=26.3707571801567, Blast_Score=96, Evalue=7e-21,
Organism=Saccharomyces cerevisiae, GI6323961, Length=375, Percent_Identity=27.4666666666667, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6324486, Length=379, Percent_Identity=25.065963060686, Blast_Score=77, Evalue=5e-15,
Organism=Saccharomyces cerevisiae, GI6319621, Length=265, Percent_Identity=28.6792452830189, Blast_Score=76, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR002328
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40251; Mature: 40251

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQISDLPTTMRAVLLTGFGGIDKLEYREDVPVPTPRDGEVLIKVGACGMNNTDINTRTR
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEE
WYGRDVNTSLSEDFGLTGAENVTGADTKQQKAWKDDSVDFPRIQGAAIAGTIVAIGPSVS
EECCCCCCCCHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCC
DRQVGNRVLVDPCIRDLSLPRRAQLSQYIGKDVNGGFAEYAVVPAINAHVLETSLSDAEL
HHHHCCEEEECHHHHHCCCCHHHHHHHHHCCCCCCCHHHEEEECCCCHHHEECCCCCCCE
ATFPTSYDTAEEMLVRARLSEGETVVITGAAGGVGSALIQLSLIRGARVIAIAGESKGER
EECCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCE
LLALGAHHFVARESADVRGQIEALVGERAVHVVADVVGGEFFPDALKLLGRGGRFTTGGA
EEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEECCCC
IGGPIQPFDLRDLIYKDLEMYGITNPLPETFKSVVDYIASGQLKPILEKAYPLKELPTAQ
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHCCCCH
SDMVKRSHLGKLVIIP
HHHHHHHHCCCEEEEC
>Mature Secondary Structure
MNQISDLPTTMRAVLLTGFGGIDKLEYREDVPVPTPRDGEVLIKVGACGMNNTDINTRTR
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCEE
WYGRDVNTSLSEDFGLTGAENVTGADTKQQKAWKDDSVDFPRIQGAAIAGTIVAIGPSVS
EECCCCCCCCHHHCCCCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCEEEEEEEEECCCCC
DRQVGNRVLVDPCIRDLSLPRRAQLSQYIGKDVNGGFAEYAVVPAINAHVLETSLSDAEL
HHHHCCEEEECHHHHHCCCCHHHHHHHHHCCCCCCCHHHEEEECCCCHHHEECCCCCCCE
ATFPTSYDTAEEMLVRARLSEGETVVITGAAGGVGSALIQLSLIRGARVIAIAGESKGER
EECCCCCCHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCCCCE
LLALGAHHFVARESADVRGQIEALVGERAVHVVADVVGGEFFPDALKLLGRGGRFTTGGA
EEEECCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCEECCCC
IGGPIQPFDLRDLIYKDLEMYGITNPLPETFKSVVDYIASGQLKPILEKAYPLKELPTAQ
CCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCCHHHCCCCH
SDMVKRSHLGKLVIIP
HHHHHHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA