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The map label for this gene is dppA [H]

Identifier: 209552123

GI number: 209552123

Start: 220856

End: 222391

Strand: Reverse

Name: dppA [H]

Synonym: Rleg2_6274

Alternate gene names: 209552123

Gene position: 222391-220856 (Counterclockwise)

Preceding gene: 209552125

Following gene: 209552122

Centisome position: 72.03

GC content: 55.01

Gene sequence:

>1536_bases
ATGCAGTACCTGAATCGCAGACGTTTCATGCAACTCTCCGCTGCCGTGGCAGCGTCGGGATTTGCGCCTGGATTTGCAAG
GGCCGAAGGTAAGCGCGGCGGCCATCTCCGCGTGGGTTTGGCCGGAGGCTCGTCACAGGATACCCTTGATCAGCTCACCT
ACGTGTCCGATGCGACTTGGATATTTTCCAGCAACGTAAGAAACAACCTCGTTGAAATTGATGAACTGAACCAACAGGTG
CCTGGTCTCGCGGAGCGCTGGGAGGTTTCACCGGACGCGACCCGGTTCTCCTTTTTTATACGAAAAGGCGTGACCTTCCA
CAGCGGAAAAACTCTCACCGCCGACGATGTCGTTGCCTCTCTCAATATTCATCGGGGAGAGACATCCCAGTCGCCGGCAA
AGGAGGAAATGCGCGATGTTGTCGACATCAAGGCTGACGGATCCCGCGTCGATGTCACGTTCTCTACCCCCAACATCGAT
TTTCTTAGTCTCGTCACCACGTTCAATTTTGGTATCCTGCCCGTTGCCGATGGCAAGATCGACAGGCTGACGAAGGACGG
CACCGGCCCTTACATGCTTGAAAGCTTCGAACCCGGTCAAAGCATAATCCTGAAACGAAATCCCAATTACTGGAAACCGG
AGGCGGGCTTTTTCGATACCGCTGAAGTGACGTTCATCGAAGATGATGCCGCTCGCATGAACGCTATTAGGACAGGCTTG
GTCGACGTCGTGAACAAGGTCGACTTAAAGACCGCATCGGTGCTGAAGCGCGTCAAAGGTATCCGGGTGGAGGATATCAA
GACTGAGCAATTCAACTCCTTCGCCATGATGATCGACACCGCCCCGTTCAATGACAACAATATCCGGCTGGCATTGAAAT
ACGGGGTCAACCGCGAGGAACTGGTCAAAAAAATTCTCCTAGGTTACGGCTCGATCGGCAATGACCATCCGGTCGGCGTC
ACCAACAAGTTTTTCAATTCACAAATACAGCAGACCGAGTTCGACGCCGACAAGGCGAAATACTACTTGAAGCAAGCTGG
CCTCACGAGGCTCGACGTGTCGCTCAGCGCCTCAGATGCAGGCTTTCCCGGCGCCGTCGGATCCTCCTCCCTTTACCAGT
CGTCCGCTGCGGCGGCGGGCATCAACATCAACGTCGTCCGGGAACCCAATGACGGCTTCTATGAGAATGTCTGGTTGAAG
AAGCCGTTTGCGACTGTCTTCTGGGGGAAGCTCGCATCGGTCGGGCTGCAGTTTTCGCAAGCGTATCTGCCCGGAGCCAC
GTGGAACGAAACCCATTGCAATCTACCGCAGGTCACGGAGTTGATCCGCACCGCCCGCGGAATCGTGGACGAAACGAAGC
GAGGCGAGATCTATCACGAACTCCAGTCGGTCATTCACGAACAAGGGGGATCGATCATCCCGATGTTCACCAATTTCGTC
TGGGCCGTGCGAGACAACGTGCAGCACGGACCGAACTTGCAGAACGATCTGACACTGGACGGTCTGAAATGCTTTCAGCG
TTGGTGGTTCGCCTAG

Upstream 100 bases:

>100_bases
CCGGCTATGGCCGCGGCGTTCCCGGCTCCAACCAGAGTGCACGTTTTCAGAACAGAGCCCGCCTGTGGGTGGAGCGAACG
TTTCTCAGCGGAGGTTGCAA

Downstream 100 bases:

>100_bases
TCGGATCAGCATGGACACGGCATCTCGATGCGCTCCCAATAAACGGATCGGCAAACTTTCAAGTCAGGGACCGGGGCGGG
TGCCGCGCTCCCTGAGAAAC

Product: extracellular solute-binding protein family 5

Products: ADP; phosphate; dipeptides [Cytoplasm] [C]

Alternate protein names: Dipeptide-binding protein; DBP [H]

Number of amino acids: Translated: 511; Mature: 511

Protein sequence:

>511_residues
MQYLNRRRFMQLSAAVAASGFAPGFARAEGKRGGHLRVGLAGGSSQDTLDQLTYVSDATWIFSSNVRNNLVEIDELNQQV
PGLAERWEVSPDATRFSFFIRKGVTFHSGKTLTADDVVASLNIHRGETSQSPAKEEMRDVVDIKADGSRVDVTFSTPNID
FLSLVTTFNFGILPVADGKIDRLTKDGTGPYMLESFEPGQSIILKRNPNYWKPEAGFFDTAEVTFIEDDAARMNAIRTGL
VDVVNKVDLKTASVLKRVKGIRVEDIKTEQFNSFAMMIDTAPFNDNNIRLALKYGVNREELVKKILLGYGSIGNDHPVGV
TNKFFNSQIQQTEFDADKAKYYLKQAGLTRLDVSLSASDAGFPGAVGSSSLYQSSAAAAGININVVREPNDGFYENVWLK
KPFATVFWGKLASVGLQFSQAYLPGATWNETHCNLPQVTELIRTARGIVDETKRGEIYHELQSVIHEQGGSIIPMFTNFV
WAVRDNVQHGPNLQNDLTLDGLKCFQRWWFA

Sequences:

>Translated_511_residues
MQYLNRRRFMQLSAAVAASGFAPGFARAEGKRGGHLRVGLAGGSSQDTLDQLTYVSDATWIFSSNVRNNLVEIDELNQQV
PGLAERWEVSPDATRFSFFIRKGVTFHSGKTLTADDVVASLNIHRGETSQSPAKEEMRDVVDIKADGSRVDVTFSTPNID
FLSLVTTFNFGILPVADGKIDRLTKDGTGPYMLESFEPGQSIILKRNPNYWKPEAGFFDTAEVTFIEDDAARMNAIRTGL
VDVVNKVDLKTASVLKRVKGIRVEDIKTEQFNSFAMMIDTAPFNDNNIRLALKYGVNREELVKKILLGYGSIGNDHPVGV
TNKFFNSQIQQTEFDADKAKYYLKQAGLTRLDVSLSASDAGFPGAVGSSSLYQSSAAAAGININVVREPNDGFYENVWLK
KPFATVFWGKLASVGLQFSQAYLPGATWNETHCNLPQVTELIRTARGIVDETKRGEIYHELQSVIHEQGGSIIPMFTNFV
WAVRDNVQHGPNLQNDLTLDGLKCFQRWWFA
>Mature_511_residues
MQYLNRRRFMQLSAAVAASGFAPGFARAEGKRGGHLRVGLAGGSSQDTLDQLTYVSDATWIFSSNVRNNLVEIDELNQQV
PGLAERWEVSPDATRFSFFIRKGVTFHSGKTLTADDVVASLNIHRGETSQSPAKEEMRDVVDIKADGSRVDVTFSTPNID
FLSLVTTFNFGILPVADGKIDRLTKDGTGPYMLESFEPGQSIILKRNPNYWKPEAGFFDTAEVTFIEDDAARMNAIRTGL
VDVVNKVDLKTASVLKRVKGIRVEDIKTEQFNSFAMMIDTAPFNDNNIRLALKYGVNREELVKKILLGYGSIGNDHPVGV
TNKFFNSQIQQTEFDADKAKYYLKQAGLTRLDVSLSASDAGFPGAVGSSSLYQSSAAAAGININVVREPNDGFYENVWLK
KPFATVFWGKLASVGLQFSQAYLPGATWNETHCNLPQVTELIRTARGIVDETKRGEIYHELQSVIHEQGGSIIPMFTNFV
WAVRDNVQHGPNLQNDLTLDGLKCFQRWWFA

Specific function: Dipeptide-binding protein of a transport system that can be subject to osmotic shock. DppA is also required for peptide chemotaxis [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 5 family [H]

Homologues:

Organism=Escherichia coli, GI1789966, Length=507, Percent_Identity=26.232741617357, Blast_Score=122, Evalue=6e-29,
Organism=Escherichia coli, GI1787495, Length=460, Percent_Identity=21.5217391304348, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787762, Length=476, Percent_Identity=23.3193277310924, Blast_Score=82, Evalue=8e-17,
Organism=Escherichia coli, GI1787052, Length=317, Percent_Identity=22.397476340694, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1789887, Length=441, Percent_Identity=21.9954648526077, Blast_Score=79, Evalue=7e-16,
Organism=Escherichia coli, GI1787551, Length=349, Percent_Identity=21.7765042979943, Blast_Score=76, Evalue=7e-15,

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 40 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000914 [H]

Pfam domain/function: PF00496 SBP_bac_5 [H]

EC number: NA

Molecular weight: Translated: 56695; Mature: 56695

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: PS00697 DNA_LIGASE_A1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYLNRRRFMQLSAAVAASGFAPGFARAEGKRGGHLRVGLAGGSSQDTLDQLTYVSDATW
CCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEE
IFSSNVRNNLVEIDELNQQVPGLAERWEVSPDATRFSFFIRKGVTFHSGKTLTADDVVAS
EEECCHHCCCEEHHHHHHHCCCHHHHCCCCCCHHHHHHHHHCCCEEECCCEEEHHHHEEE
LNIHRGETSQSPAKEEMRDVVDIKADGSRVDVTFSTPNIDFLSLVTTFNFGILPVADGKI
EEEECCCCCCCCHHHHHHHHEEEECCCCEEEEEECCCCCHHHHHHHHHCCCEEEECCCCH
DRLTKDGTGPYMLESFEPGQSIILKRNPNYWKPEAGFFDTAEVTFIEDDAARMNAIRTGL
HHHCCCCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHH
VDVVNKVDLKTASVLKRVKGIRVEDIKTEQFNSFAMMIDTAPFNDNNIRLALKYGVNREE
HHHHHHHCCHHHHHHHHHHCCEEEECCCCCCCCEEEEEEECCCCCCCEEEEEEECCCHHH
LVKKILLGYGSIGNDHPVGVTNKFFNSQIQQTEFDADKAKYYLKQAGLTRLDVSLSASDA
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEEECCCC
GFPGAVGSSSLYQSSAAAAGININVVREPNDGFYENVWLKKPFATVFWGKLASVGLQFSQ
CCCCCCCCCHHHHCCHHHCCCEEEEEECCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHH
AYLPGATWNETHCNLPQVTELIRTARGIVDETKRGEIYHELQSVIHEQGGSIIPMFTNFV
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHH
WAVRDNVQHGPNLQNDLTLDGLKCFQRWWFA
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MQYLNRRRFMQLSAAVAASGFAPGFARAEGKRGGHLRVGLAGGSSQDTLDQLTYVSDATW
CCCHHHHHHHHHHHHHHHCCCCCCHHHCCCCCCCEEEEEECCCCCCHHHHHHHHHCCCEE
IFSSNVRNNLVEIDELNQQVPGLAERWEVSPDATRFSFFIRKGVTFHSGKTLTADDVVAS
EEECCHHCCCEEHHHHHHHCCCHHHHCCCCCCHHHHHHHHHCCCEEECCCEEEHHHHEEE
LNIHRGETSQSPAKEEMRDVVDIKADGSRVDVTFSTPNIDFLSLVTTFNFGILPVADGKI
EEEECCCCCCCCHHHHHHHHEEEECCCCEEEEEECCCCCHHHHHHHHHCCCEEEECCCCH
DRLTKDGTGPYMLESFEPGQSIILKRNPNYWKPEAGFFDTAEVTFIEDDAARMNAIRTGL
HHHCCCCCCCEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCHHHHHHHHHHH
VDVVNKVDLKTASVLKRVKGIRVEDIKTEQFNSFAMMIDTAPFNDNNIRLALKYGVNREE
HHHHHHHCCHHHHHHHHHHCCEEEECCCCCCCCEEEEEEECCCCCCCEEEEEEECCCHHH
LVKKILLGYGSIGNDHPVGVTNKFFNSQIQQTEFDADKAKYYLKQAGLTRLDVSLSASDA
HHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHCCCEEEEEEEECCCC
GFPGAVGSSSLYQSSAAAAGININVVREPNDGFYENVWLKKPFATVFWGKLASVGLQFSQ
CCCCCCCCCHHHHCCHHHCCCEEEEEECCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHH
AYLPGATWNETHCNLPQVTELIRTARGIVDETKRGEIYHELQSVIHEQGGSIIPMFTNFV
HCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCEEEHHHHHH
WAVRDNVQHGPNLQNDLTLDGLKCFQRWWFA
HHHHCCCCCCCCCCCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; dipeptides [Periplasm]; H2O [C]

Specific reaction: ATP + dipeptides [Periplasm] + H2O = ADP + phosphate + dipeptides [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1702779; 1956284; 7536291; 8041620; 9278503; 9298646; 9600841; 8563629; 8527431 [H]