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The map label for this gene is aapQ [H]

Identifier: 209549161

GI number: 209549161

Start: 1586829

End: 1588031

Strand: Reverse

Name: aapQ [H]

Synonym: Rleg2_1562

Alternate gene names: 209549161

Gene position: 1588031-1586829 (Counterclockwise)

Preceding gene: 209549162

Following gene: 209549160

Centisome position: 34.99

GC content: 58.27

Gene sequence:

>1203_bases
ATGACGCATGGGGCTGTGGATAGGACACCTTTGCATGACACCGGCTGGACTTTCCGGTCGGCAATGTACGATCCGAAATA
CCGGAGCATATTCTTCCAGATTCTAACAATCGTTGTTCTCGTGGCGTTCGTGTGGTGGGTGGCCCACAACACGGCCGTGA
ACCTTGCCCGCAGCAATACGGCATCCGGTTTCGGCTTTCTTCGCGGTCGCGCCGGTTTCGAAATCGGCCAGTCGCTGATC
GGCTATTCAAGCGACTCGACTTATGCACGCGCGCTTTTCGTCGGTATTCTGAATACCTTGCTGGTGGCGGTAACCGGTAT
CGTCACGGCAACCATCATCGGGTTCATTATCGGGATCGGCCGGTTGTCGCGGAACTGGCTGATTGCCAAGCTCAGCACGG
TCTATGTCGAAATCTTCCGCAATATTCCGCCGCTGCTCGTCATCTTCTTCTGGTATCTCGGCGTTCTCTCCGTCCTGCCG
CAGCCGCGCGAATCGGTGGGGCTGCCGTTCAGCATGTTCCTCAACAACAGAGGACTAGCCTTCCCGAAGCCGATCTTCGA
GACAGGCATGGTAGCGGTCGGCATTGCCCTGCTGATTGCGATTGTCGCCGCCATCATCATGGCGCGCTGGGCTCATAAAC
GACAGGCCGCAACCGGCCAGCCGTTCCATACGGTATGGGCGTCGATCGCGCTGATCGTCGGCCTACCATTGCTGGTCTTC
GTGGCCTCGGGCTTTCCGCTCACCTTCGATGTTCCCGTCGCCGGAAAGTTCAATCTGACGGGCGGCTCGGTCGTCGGCCC
CGAATTCATGTCGCTGTTTCTCGCTCTGTCCTTTTATACCGCCTCGTTCATCGCCGAGATCGTTCGTGGCGGCATTCGCG
GCGTTCCAAAGGGACAATCCGAGGCAGCCGGCGCGCTGGGGCTGCATCCGTCGAACGTGACGAGACTTGTCGTGGTGCCG
CAGGCGCTGCGCATCATCATTCCGCCGCTGACAAGCCAATACCTGAACCTGACCAAGAACTCCTCGCTCGCCATCGCGAT
CGGTTTCTCCGATCTCGTTGCCGTCGGCGGCACGATCCTCAATCAGAGCGGTCAAGCGATCGAGATCGTGTGCATCTGGG
GTATCGCCTATCTCAGCCTGAGCATTCTCACGTCGCTGTTCATGAATTGGTTCAATGCCAAGATGGCACTGGTGGAGAGA
TAA

Upstream 100 bases:

>100_bases
GAGCCTTGGCATGAAATGCCGGGAAGGCGGCCAGCCGCCTTCCCGCTTCTAAAAAGTCAAAAAGAAAGCCCGAAAACGGG
CACAAGGGGATTGGCGCGGC

Downstream 100 bases:

>100_bases
GATGTCGGTCGCCGATAAACCCTTCGTCAGAACGTCCATCCTTGCTGCCGAACCGCCGCCCCGCGGCGAGAGGGGAGCCG
TTGCCTGGATACGCCGCAAC

Product: polar amino acid ABC transporter inner membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 400; Mature: 399

Protein sequence:

>400_residues
MTHGAVDRTPLHDTGWTFRSAMYDPKYRSIFFQILTIVVLVAFVWWVAHNTAVNLARSNTASGFGFLRGRAGFEIGQSLI
GYSSDSTYARALFVGILNTLLVAVTGIVTATIIGFIIGIGRLSRNWLIAKLSTVYVEIFRNIPPLLVIFFWYLGVLSVLP
QPRESVGLPFSMFLNNRGLAFPKPIFETGMVAVGIALLIAIVAAIIMARWAHKRQAATGQPFHTVWASIALIVGLPLLVF
VASGFPLTFDVPVAGKFNLTGGSVVGPEFMSLFLALSFYTASFIAEIVRGGIRGVPKGQSEAAGALGLHPSNVTRLVVVP
QALRIIIPPLTSQYLNLTKNSSLAIAIGFSDLVAVGGTILNQSGQAIEIVCIWGIAYLSLSILTSLFMNWFNAKMALVER

Sequences:

>Translated_400_residues
MTHGAVDRTPLHDTGWTFRSAMYDPKYRSIFFQILTIVVLVAFVWWVAHNTAVNLARSNTASGFGFLRGRAGFEIGQSLI
GYSSDSTYARALFVGILNTLLVAVTGIVTATIIGFIIGIGRLSRNWLIAKLSTVYVEIFRNIPPLLVIFFWYLGVLSVLP
QPRESVGLPFSMFLNNRGLAFPKPIFETGMVAVGIALLIAIVAAIIMARWAHKRQAATGQPFHTVWASIALIVGLPLLVF
VASGFPLTFDVPVAGKFNLTGGSVVGPEFMSLFLALSFYTASFIAEIVRGGIRGVPKGQSEAAGALGLHPSNVTRLVVVP
QALRIIIPPLTSQYLNLTKNSSLAIAIGFSDLVAVGGTILNQSGQAIEIVCIWGIAYLSLSILTSLFMNWFNAKMALVER
>Mature_399_residues
THGAVDRTPLHDTGWTFRSAMYDPKYRSIFFQILTIVVLVAFVWWVAHNTAVNLARSNTASGFGFLRGRAGFEIGQSLIG
YSSDSTYARALFVGILNTLLVAVTGIVTATIIGFIIGIGRLSRNWLIAKLSTVYVEIFRNIPPLLVIFFWYLGVLSVLPQ
PRESVGLPFSMFLNNRGLAFPKPIFETGMVAVGIALLIAIVAAIIMARWAHKRQAATGQPFHTVWASIALIVGLPLLVFV
ASGFPLTFDVPVAGKFNLTGGSVVGPEFMSLFLALSFYTASFIAEIVRGGIRGVPKGQSEAAGALGLHPSNVTRLVVVPQ
ALRIIIPPLTSQYLNLTKNSSLAIAIGFSDLVAVGGTILNQSGQAIEIVCIWGIAYLSLSILTSLFMNWFNAKMALVER

Specific function: Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG4597

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI48994930, Length=379, Percent_Identity=51.9788918205805, Blast_Score=342, Evalue=2e-95,
Organism=Escherichia coli, GI1786874, Length=129, Percent_Identity=37.984496124031, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1786873, Length=129, Percent_Identity=30.2325581395349, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1788226, Length=130, Percent_Identity=30, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787030, Length=179, Percent_Identity=29.0502793296089, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082239, Length=75, Percent_Identity=44, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1788645, Length=161, Percent_Identity=30.4347826086957, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787087, Length=225, Percent_Identity=25.7777777777778, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 43249; Mature: 43117

Theoretical pI: Translated: 10.58; Mature: 10.58

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
THGAVDRTPLHDTGWTFRSAMYDPKYRSIFFQILTIVVLVAFVWWVAHNTAVNLARSNT
CCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
ASGFGFLRGRAGFEIGQSLIGYSSDSTYARALFVGILNTLLVAVTGIVTATIIGFIIGIG
CCCCHHHCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RLSRNWLIAKLSTVYVEIFRNIPPLLVIFFWYLGVLSVLPQPRESVGLPFSMFLNNRGLA
HHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCHHHHCCCHHHHCCCCCCC
FPKPIFETGMVAVGIALLIAIVAAIIMARWAHKRQAATGQPFHTVWASIALIVGLPLLVF
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHH
VASGFPLTFDVPVAGKFNLTGGSVVGPEFMSLFLALSFYTASFIAEIVRGGIRGVPKGQS
HHCCCCEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCC
EAAGALGLHPSNVTRLVVVPQALRIIIPPLTSQYLNLTKNSSLAIAIGFSDLVAVGGTIL
CCCCCCCCCCCCCEEEEEEHHHHHHHCCCHHHHHHHHCCCCCEEEEECHHHHHHHHHHHC
NQSGQAIEIVCIWGIAYLSLSILTSLFMNWFNAKMALVER
CCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8898392 [H]