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The map label for this gene is aapM [H]

Identifier: 209549160

GI number: 209549160

Start: 1585673

End: 1586827

Strand: Reverse

Name: aapM [H]

Synonym: Rleg2_1561

Alternate gene names: 209549160

Gene position: 1586827-1585673 (Counterclockwise)

Preceding gene: 209549161

Following gene: 209549159

Centisome position: 34.97

GC content: 59.83

Gene sequence:

>1155_bases
ATGTCGGTCGCCGATAAACCCTTCGTCAGAACGTCCATCCTTGCTGCCGAACCGCCGCCCCGCGGCGAGAGGGGAGCCGT
TGCCTGGATACGCCGCAACCTCCTGGCAACTCCGAAAGACGTGATCCTGACAATCCTGGCTGTTGCGCTGATCGCATGGG
CCGTGCCGCATCTCGTCAACTGGCTGTTCATCCAGGCCGTATGGTCCGGGCCCGACCGCACATTCTGCGCGACGACAATC
CAGGGCGGCATCCAGCCCGAGGGCTGGAGTGGCGCGTGCTGGGCCTTCGTCAGCGCCAAGTACGATCAGTTTATCTTCGG
CCGCTATCCGCTCGACGAGCGCTGGAGACCGGCGATCGTCGGGATCCTCTTCATTCTGCTTCTGGTTCCGATGCTGATCC
CGTCGGCGCCGCGCAAGGGCCTGAACGCCATTCTTCTGTTCGCCGCCCTGCCGATCATCGCCTTCTGGCTTCTTCACGGC
GGGTACGGCCTCGAAGTGGTGGAGACACCGCTCTGGGGCGGGTTGATGGTGACGCTCGTCCTGTCCTTTGTCGGCATTGC
AGTGTCATTGCCCTGCGGTATTCTGCTTGCACTGGGACGCCGTTCGAAGATGCCGGTCATCCGCATGCTCTGCGTGACCT
TCATCGAGGTCATTCGAGGCGTTCCGCTGATCACCGTCCTGTTCATGGCAAGCGTGATGTTGCCGCTCTTCCTTCCCACA
GGCTGGAACGTGGACAAACTGCTTCGGGCACTGATCGGCGTGTCGATCTTCACGTCGGCCTATATGGCCGAAGTGATCCG
TGGCGGTCTTCAAGCGATTCCGAAGGGACAGTTCGAAGGCGCCGATTCACTTGGCCTCGGCTATTGGCAAAAGACCCGGC
TGATCATCATGCCGCAGGCCATCAAGCTAGTAATCCCGAGCATCGTCAACACCTTCATCGGAACCTTCAAGGACACGTCG
CTGGTCACCATTATCGGCATGTTCGATCTGCTCGGTATTGTGAAGCAGAACTTCTCCGATGCCAACTGGGCAAGCGCCGT
CACGCCGATTACGGGCCTGATCTTCGCGGGCTTCATCTTCTGGCTGTTCTGCTTCGGCATGTCTCGCTATTCGGGCTTCA
TGGAACGCCATCTCGATACCGGCCACAAACGATAA

Upstream 100 bases:

>100_bases
ATCGTGTGCATCTGGGGTATCGCCTATCTCAGCCTGAGCATTCTCACGTCGCTGTTCATGAATTGGTTCAATGCCAAGAT
GGCACTGGTGGAGAGATAAG

Downstream 100 bases:

>100_bases
GAACGCTAAAACGATAAGAATGAGGGAAAACAATCATGGCTGAAGCTCCAGCTAAAAAGCTCACCGTTTCCGCAACGGAA
GTGGCGGTCGATATCATCAA

Product: polar amino acid ABC transporter inner membrane subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MSVADKPFVRTSILAAEPPPRGERGAVAWIRRNLLATPKDVILTILAVALIAWAVPHLVNWLFIQAVWSGPDRTFCATTI
QGGIQPEGWSGACWAFVSAKYDQFIFGRYPLDERWRPAIVGILFILLLVPMLIPSAPRKGLNAILLFAALPIIAFWLLHG
GYGLEVVETPLWGGLMVTLVLSFVGIAVSLPCGILLALGRRSKMPVIRMLCVTFIEVIRGVPLITVLFMASVMLPLFLPT
GWNVDKLLRALIGVSIFTSAYMAEVIRGGLQAIPKGQFEGADSLGLGYWQKTRLIIMPQAIKLVIPSIVNTFIGTFKDTS
LVTIIGMFDLLGIVKQNFSDANWASAVTPITGLIFAGFIFWLFCFGMSRYSGFMERHLDTGHKR

Sequences:

>Translated_384_residues
MSVADKPFVRTSILAAEPPPRGERGAVAWIRRNLLATPKDVILTILAVALIAWAVPHLVNWLFIQAVWSGPDRTFCATTI
QGGIQPEGWSGACWAFVSAKYDQFIFGRYPLDERWRPAIVGILFILLLVPMLIPSAPRKGLNAILLFAALPIIAFWLLHG
GYGLEVVETPLWGGLMVTLVLSFVGIAVSLPCGILLALGRRSKMPVIRMLCVTFIEVIRGVPLITVLFMASVMLPLFLPT
GWNVDKLLRALIGVSIFTSAYMAEVIRGGLQAIPKGQFEGADSLGLGYWQKTRLIIMPQAIKLVIPSIVNTFIGTFKDTS
LVTIIGMFDLLGIVKQNFSDANWASAVTPITGLIFAGFIFWLFCFGMSRYSGFMERHLDTGHKR
>Mature_383_residues
SVADKPFVRTSILAAEPPPRGERGAVAWIRRNLLATPKDVILTILAVALIAWAVPHLVNWLFIQAVWSGPDRTFCATTIQ
GGIQPEGWSGACWAFVSAKYDQFIFGRYPLDERWRPAIVGILFILLLVPMLIPSAPRKGLNAILLFAALPIIAFWLLHGG
YGLEVVETPLWGGLMVTLVLSFVGIAVSLPCGILLALGRRSKMPVIRMLCVTFIEVIRGVPLITVLFMASVMLPLFLPTG
WNVDKLLRALIGVSIFTSAYMAEVIRGGLQAIPKGQFEGADSLGLGYWQKTRLIIMPQAIKLVIPSIVNTFIGTFKDTSL
VTIIGMFDLLGIVKQNFSDANWASAVTPITGLIFAGFIFWLFCFGMSRYSGFMERHLDTGHKR

Specific function: Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082239, Length=376, Percent_Identity=48.6702127659575, Blast_Score=354, Evalue=4e-99,
Organism=Escherichia coli, GI1788226, Length=216, Percent_Identity=35.1851851851852, Blast_Score=111, Evalue=8e-26,
Organism=Escherichia coli, GI1786873, Length=217, Percent_Identity=29.0322580645161, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1787030, Length=182, Percent_Identity=34.0659340659341, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1786874, Length=187, Percent_Identity=24.5989304812834, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI48994930, Length=82, Percent_Identity=40.2439024390244, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788646, Length=219, Percent_Identity=26.027397260274, Blast_Score=72, Evalue=7e-14,
Organism=Escherichia coli, GI1788645, Length=199, Percent_Identity=25.6281407035176, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787086, Length=169, Percent_Identity=28.4023668639053, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787087, Length=183, Percent_Identity=26.2295081967213, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 42246; Mature: 42115

Theoretical pI: Translated: 10.11; Mature: 10.11

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVADKPFVRTSILAAEPPPRGERGAVAWIRRNLLATPKDVILTILAVALIAWAVPHLVN
CCCCCCCCHHHHHEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
WLFIQAVWSGPDRTFCATTIQGGIQPEGWSGACWAFVSAKYDQFIFGRYPLDERWRPAIV
HHHHHHHHCCCCCCEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
GILFILLLVPMLIPSAPRKGLNAILLFAALPIIAFWLLHGGYGLEVVETPLWGGLMVTLV
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHH
LSFVGIAVSLPCGILLALGRRSKMPVIRMLCVTFIEVIRGVPLITVLFMASVMLPLFLPT
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
GWNVDKLLRALIGVSIFTSAYMAEVIRGGLQAIPKGQFEGADSLGLGYWQKTRLIIMPQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCEEEEEHHH
IKLVIPSIVNTFIGTFKDTSLVTIIGMFDLLGIVKQNFSDANWASAVTPITGLIFAGFIF
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
WLFCFGMSRYSGFMERHLDTGHKR
HHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
SVADKPFVRTSILAAEPPPRGERGAVAWIRRNLLATPKDVILTILAVALIAWAVPHLVN
CCCCCCCHHHHHEECCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHH
WLFIQAVWSGPDRTFCATTIQGGIQPEGWSGACWAFVSAKYDQFIFGRYPLDERWRPAIV
HHHHHHHHCCCCCCEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCHHHHH
GILFILLLVPMLIPSAPRKGLNAILLFAALPIIAFWLLHGGYGLEVVETPLWGGLMVTLV
HHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCHHHHHHHHH
LSFVGIAVSLPCGILLALGRRSKMPVIRMLCVTFIEVIRGVPLITVLFMASVMLPLFLPT
HHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCC
GWNVDKLLRALIGVSIFTSAYMAEVIRGGLQAIPKGQFEGADSLGLGYWQKTRLIIMPQA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHCCEEEEEHHH
IKLVIPSIVNTFIGTFKDTSLVTIIGMFDLLGIVKQNFSDANWASAVTPITGLIFAGFIF
HHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
WLFCFGMSRYSGFMERHLDTGHKR
HHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8898392 [H]