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The map label for this gene is soxS

Identifier: 209398875

GI number: 209398875

Start: 5205407

End: 5205730

Strand: Reverse

Name: soxS

Synonym: ECH74115_5565

Alternate gene names: 209398875

Gene position: 5205730-5205407 (Counterclockwise)

Preceding gene: 209396870

Following gene: 209399303

Centisome position: 93.43

GC content: 51.23

Gene sequence:

>324_bases
ATGTCCCATCAGAAAATTATTCAGGATCTTATCGCATGGATTGACGAGCATATTGACCAGCCGCTTAACATTGATGTCGT
CGCAAAAAAATCAGGCTATTCAAAGTGGTACCTGCAACGGATGTTCCGCACGGTGACGCATCAGACGCTTGGCGATTACA
TTCGTCAACGCCGTCTGTTACTGGCCGCCGTTGAGTTGCGCACCACCGAGCGTCCGATTTTTGATATCGCAATGGACCTG
GGTTATGTCTCTCAGCAGACCTTCTCCCGCGTTTTCCGTCGGCAGTTTGATCGCACTCCCAGCGATTATCGCCACCGCCT
GTAG

Upstream 100 bases:

>100_bases
TAATTTCTTTTCCATAAATCGCTTTACCTCAAGTTAACTTGAGGAATTATACTCCCCAACAGATGAATTAACGAACTGAA
CACTGAAAAGAGGCAGATTT

Downstream 100 bases:

>100_bases
TTTTATTGCCCGCGCGTTAACTCCCGCGCGGGTAATTGCTCCATCCATTGCATAAACACCTGCGGCGGCATCGCCTTCGC
AAAGAACCATCCCTGGCAAT

Product: DNA-binding transcriptional regulator SoxS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 107; Mature: 106

Protein sequence:

>107_residues
MSHQKIIQDLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDL
GYVSQQTFSRVFRRQFDRTPSDYRHRL

Sequences:

>Translated_107_residues
MSHQKIIQDLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDL
GYVSQQTFSRVFRRQFDRTPSDYRHRL
>Mature_106_residues
SHQKIIQDLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDLG
YVSQQTFSRVFRRQFDRTPSDYRHRL

Specific function: Transcriptional activator of the superoxide response regulon of E.coli that includes at least 10 genes such as sodA, nfo, zwf and micF. Binds the DNA sequence 5'-GCACN(7)CAA-3'. It also facilitates the subsequent binding of RNA polymerase to the micF and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm (Probable)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain

Homologues:

Organism=Escherichia coli, GI1790497, Length=107, Percent_Identity=100, Blast_Score=220, Evalue=2e-59,
Organism=Escherichia coli, GI1790857, Length=104, Percent_Identity=55.7692307692308, Blast_Score=124, Evalue=9e-31,
Organism=Escherichia coli, GI87081928, Length=98, Percent_Identity=41.8367346938776, Blast_Score=97, Evalue=3e-22,

Paralogues:

None

Copy number: 2500 (L-broth) [C]

Swissprot (AC and ID): SOXS_ECO57 (P0A9E4)

Other databases:

- EMBL:   AE005174
- EMBL:   BA000007
- PIR:   D91259
- PIR:   H86099
- RefSeq:   NP_290695.1
- RefSeq:   NP_313071.1
- ProteinModelPortal:   P0A9E4
- SMR:   P0A9E4
- EnsemblBacteria:   EBESCT00000025926
- EnsemblBacteria:   EBESCT00000058681
- GeneID:   914293
- GeneID:   960062
- GenomeReviews:   AE005174_GR
- GenomeReviews:   BA000007_GR
- KEGG:   ece:Z5661
- KEGG:   ecs:ECs5044
- GeneTree:   EBGT00050000008637
- HOGENOM:   HBG752108
- OMA:   RRPIFDI
- ProtClustDB:   PRK10219
- BioCyc:   ECOL83334:ECS5044-MONOMER
- GO:   GO:0005737
- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR018062
- InterPro:   IPR020449
- InterPro:   IPR018060
- Gene3D:   G3DSA:1.10.10.60
- PRINTS:   PR00032
- SMART:   SM00342

Pfam domain/function: PF00165 HTH_AraC; SSF46689 Homeodomain_like

EC number: NA

Molecular weight: Translated: 12911; Mature: 12780

Theoretical pI: Translated: 10.28; Mature: 10.28

Prosite motif: PS00041 HTH_ARAC_FAMILY_1; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHQKIIQDLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGDYIRQRRLL
CCHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAVELRTTERPIFDIAMDLGYVSQQTFSRVFRRQFDRTPSDYRHRL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCC
>Mature Secondary Structure 
SHQKIIQDLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRTVTHQTLGDYIRQRRLL
CHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
LAAVELRTTERPIFDIAMDLGYVSQQTFSRVFRRQFDRTPSDYRHRL
HHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796