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The map label for this gene is mdtA [H]

Identifier: 209695423

GI number: 209695423

Start: 2104217

End: 2105389

Strand: Direct

Name: mdtA [H]

Synonym: VSAL_I1963

Alternate gene names: 209695423

Gene position: 2104217-2105389 (Clockwise)

Preceding gene: 209695420

Following gene: 209695426

Centisome position: 63.28

GC content: 37.51

Gene sequence:

>1173_bases
GTGATTGTTTTTACAGTTTATTGCGTCATCTTTACATTCATTGACGAACAAATGCCTTTTCACTTGGTAAACTATGTTCA
CTCACTGAATTCCATAATTAAAATAAGTCACAGTATGAATCAAACAAAGTCTATCGCCCTTGCCGTTTTATTAGCATGTA
CTTTATCTACACTTTCTTATGCTAAAAGACCAACCAGTAATGAATCTGTTGCTGTTGTTGCTGAAGAAGTAGCAACTCAT
GAGATATCTCAGTCTTTATCGTTAATTGGAAAGCTTGAAGCCGCAGAATCCGTCATTATTTCACCTGAAGTTTCAGGAAA
AGTCGATCGTATTGCGATTAAGGCCAATCAAACGGTGAAAAAAGGTCAGCTATTGATTCAGTTAAATGATGATAAAGCAA
AAGCGGTAATAAAAGAGGCTCAAGCGTATTTACATGATGAACAACGTAAATTAAAAGAGTTTCAGCGTTTGTCGAAAAAG
AATGCGATTACTCAAACTGAGATTGATGGGCAAAAAGCCAGTGTAAATATTGCACAGGCACGTTTAGAAGCCGCAAATGC
TGAATTACGTGACTTACATATCTCAGCGCCTTTTGCCGGAACGGTTGGTTTTATTGATTTTAGCTTAGGTAAAATGGTCA
GTGTTGGTAGTGAATTACTTACATTGGACAACCTTTCTTTAATGCAATTGGATTTACAAGTGCCTGAGCGTTATTTATCA
ATGCTATCAACAAGGATGAAAGTCGAGGCTAAGAGCCAAGCATGGGGAGATCTTGAGTTCTCTGGTGAAGTGGTTGGTAT
TGATTCTCGTATAAATGCAGAAACACTTAATTTACGCATTCGAATTGATTTTCCTAATAAAGAACTAAAAATGAAGCCGG
GTATGTTAATGGCCGCAACGTTGGATTTTCCTGCTATTAATGCACCGATTATTCCTGTTCAAGCACTTGAGTATTCAGGT
ACAAAACGTTATGTGTATGTCATTGGTGATGATAATAAAGTGATTCGTACGGAAGTGGTTTTAGGTGCTCGTGTAGAAAA
CCGAGTGGTTATTGAAAAAGGCTTGGATATAGGCCAAGACATTGTTGTTCAAGGTCTTGTCAATATGCGTGATGGTGTAA
CGGTTAAAATGATCTCAACAGATGCTGAGACGATAAAAGCTGAGGTTCAATAA

Upstream 100 bases:

>100_bases
CACTTTTATGTGTTTTTTGATTTGAATGCTGACTTTTTCGTCATAAAGGGTTAAAAATCACCATTTATGAACTAAATGAG
TGAATAGTAGATAGATTGAA

Downstream 100 bases:

>100_bases
TGTGGTTATCTGATACGTCAGTAAAAAGACCGGTAGTTGCCATTGTTCTAAGTTTGTTGTTGTGTGTGTTTGGTGCGGTG
TCTTTTAGCAAGTTAGCCGT

Product: secretion protein, HlyD family

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 390; Mature: 390

Protein sequence:

>390_residues
MIVFTVYCVIFTFIDEQMPFHLVNYVHSLNSIIKISHSMNQTKSIALAVLLACTLSTLSYAKRPTSNESVAVVAEEVATH
EISQSLSLIGKLEAAESVIISPEVSGKVDRIAIKANQTVKKGQLLIQLNDDKAKAVIKEAQAYLHDEQRKLKEFQRLSKK
NAITQTEIDGQKASVNIAQARLEAANAELRDLHISAPFAGTVGFIDFSLGKMVSVGSELLTLDNLSLMQLDLQVPERYLS
MLSTRMKVEAKSQAWGDLEFSGEVVGIDSRINAETLNLRIRIDFPNKELKMKPGMLMAATLDFPAINAPIIPVQALEYSG
TKRYVYVIGDDNKVIRTEVVLGARVENRVVIEKGLDIGQDIVVQGLVNMRDGVTVKMISTDAETIKAEVQ

Sequences:

>Translated_390_residues
MIVFTVYCVIFTFIDEQMPFHLVNYVHSLNSIIKISHSMNQTKSIALAVLLACTLSTLSYAKRPTSNESVAVVAEEVATH
EISQSLSLIGKLEAAESVIISPEVSGKVDRIAIKANQTVKKGQLLIQLNDDKAKAVIKEAQAYLHDEQRKLKEFQRLSKK
NAITQTEIDGQKASVNIAQARLEAANAELRDLHISAPFAGTVGFIDFSLGKMVSVGSELLTLDNLSLMQLDLQVPERYLS
MLSTRMKVEAKSQAWGDLEFSGEVVGIDSRINAETLNLRIRIDFPNKELKMKPGMLMAATLDFPAINAPIIPVQALEYSG
TKRYVYVIGDDNKVIRTEVVLGARVENRVVIEKGLDIGQDIVVQGLVNMRDGVTVKMISTDAETIKAEVQ
>Mature_390_residues
MIVFTVYCVIFTFIDEQMPFHLVNYVHSLNSIIKISHSMNQTKSIALAVLLACTLSTLSYAKRPTSNESVAVVAEEVATH
EISQSLSLIGKLEAAESVIISPEVSGKVDRIAIKANQTVKKGQLLIQLNDDKAKAVIKEAQAYLHDEQRKLKEFQRLSKK
NAITQTEIDGQKASVNIAQARLEAANAELRDLHISAPFAGTVGFIDFSLGKMVSVGSELLTLDNLSLMQLDLQVPERYLS
MLSTRMKVEAKSQAWGDLEFSGEVVGIDSRINAETLNLRIRIDFPNKELKMKPGMLMAATLDFPAINAPIIPVQALEYSG
TKRYVYVIGDDNKVIRTEVVLGARVENRVVIEKGLDIGQDIVVQGLVNMRDGVTVKMISTDAETIKAEVQ

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=330, Percent_Identity=24.2424242424242, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87081796, Length=363, Percent_Identity=26.4462809917355, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1789929, Length=396, Percent_Identity=22.7272727272727, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1789665, Length=341, Percent_Identity=26.3929618768328, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 42972; Mature: 42972

Theoretical pI: Translated: 6.28; Mature: 6.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVFTVYCVIFTFIDEQMPFHLVNYVHSLNSIIKISHSMNQTKSIALAVLLACTLSTLSY
CEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
AKRPTSNESVAVVAEEVATHEISQSLSLIGKLEAAESVIISPEVSGKVDRIAIKANQTVK
HCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEEEEECCCCEE
KGQLLIQLNDDKAKAVIKEAQAYLHDEQRKLKEFQRLSKKNAITQTEIDGQKASVNIAQA
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEHHHHH
RLEAANAELRDLHISAPFAGTVGFIDFSLGKMVSVGSELLTLDNLSLMQLDLQVPERYLS
HHHHCCCCEEEEEEECCCCCCEEEEEHHHHHHHHCCCHHEEECCCEEEEEEHHHHHHHHH
MLSTRMKVEAKSQAWGDLEFSGEVVGIDSRINAETLNLRIRIDFPNKELKMKPGMLMAAT
HHHHHHEEEECCCCCCCEEECCEEEEECCCCCCEEEEEEEEEECCCCCEEECCCEEEEEE
LDFPAINAPIIPVQALEYSGTKRYVYVIGDDNKVIRTEVVLGARVENRVVIEKGLDIGQD
ECCCCCCCCCCEEEEEECCCCEEEEEEEECCCCEEEEEEEEECCCCCEEEEECCCCCCHH
IVVQGLVNMRDGVTVKMISTDAETIKAEVQ
HHHHHHHCCCCCCEEEEEECCHHHHEEECC
>Mature Secondary Structure
MIVFTVYCVIFTFIDEQMPFHLVNYVHSLNSIIKISHSMNQTKSIALAVLLACTLSTLSY
CEEEHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHH
AKRPTSNESVAVVAEEVATHEISQSLSLIGKLEAAESVIISPEVSGKVDRIAIKANQTVK
HCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCEEEEEEECCCCEE
KGQLLIQLNDDKAKAVIKEAQAYLHDEQRKLKEFQRLSKKNAITQTEIDGQKASVNIAQA
CCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCEEHHHHH
RLEAANAELRDLHISAPFAGTVGFIDFSLGKMVSVGSELLTLDNLSLMQLDLQVPERYLS
HHHHCCCCEEEEEEECCCCCCEEEEEHHHHHHHHCCCHHEEECCCEEEEEEHHHHHHHHH
MLSTRMKVEAKSQAWGDLEFSGEVVGIDSRINAETLNLRIRIDFPNKELKMKPGMLMAAT
HHHHHHEEEECCCCCCCEEECCEEEEECCCCCCEEEEEEEEEECCCCCEEECCCEEEEEE
LDFPAINAPIIPVQALEYSGTKRYVYVIGDDNKVIRTEVVLGARVENRVVIEKGLDIGQD
ECCCCCCCCCCEEEEEECCCCEEEEEEEECCCCEEEEEEEEECCCCCEEEEECCCCCCHH
IVVQGLVNMRDGVTVKMISTDAETIKAEVQ
HHHHHHHCCCCCCEEEEEECCHHHHEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]