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The map label for this gene is ubiG [H]

Identifier: 209695247

GI number: 209695247

Start: 1882401

End: 1883126

Strand: Direct

Name: ubiG [H]

Synonym: VSAL_I1768

Alternate gene names: 209695247

Gene position: 1882401-1883126 (Clockwise)

Preceding gene: 209695245

Following gene: 209695248

Centisome position: 56.61

GC content: 39.94

Gene sequence:

>726_bases
ATGAAAAAGGAATTAAGAACTATGACTCAGCAGTTAAATGTCGATCCAGCAGAAATCAAAAAATTTGAAGATATGGCCTC
TCGTTGGTGGGATTTTGAAGGTGAATTTAAACCTCTACATCAAATCAATCCATTACGCCTTAATTATGTATTGACCAACG
CCAATGGTCTATTTGGTAAAAAAGTATTAGATGTTGGTTGTGGCGGCGGTATTTTAGCTGAGAGCATGGCAAAACAAGGT
GCAGACGTTATTGGGTTAGACATGGGGAAAGAGCCTCTAACCGTCGCTCGTCTTCATGCATTAGAAACGGGCACTATATT
AGAATATATCCAATCTACTGCAGAGCAGCACGCAGAAGAATACCCTGAAACATACGATGTAATAACCTGTATGGAAATGC
TAGAGCATGTGCCAGACCCTTTGTCTGTGATTCGTGCTTGCGCTAAAATGATAAAACCAGGTGGGCATGTATTTTTCTCC
ACCTTAAACCGCAATATCAAATCCTATCTGTTTGCCATTGTTGGCGCAGAACACGTTCTTAAATTGGTCCCAAAAGGCAC
TCATGATCACGATAAGTTCATCCGTCCTTCTGAATTATTAAAAATGCTCGATCAAACAGCATTACAAGAGCGTGGGATCA
CTGGTCTTCATTACAATCCATTAACAGACGCTTATTCATTAGGCACAAATGTTGATGTTAATTACATCGTTCATACAACG
CTGTAA

Upstream 100 bases:

>100_bases
CAATTCATCATATTCTTGAAAAGCCTCATAAAAACCGGTGAAAAAATCGCCATTTTAAAGTCTCTCTTTCTGCTTTTTTT
CTGTATATAATAAGGAGAAG

Downstream 100 bases:

>100_bases
AATTCAGGCTCTTTATTTATTCTTAATGTAAATAAAGAGCTTTTTCTTTCTACGTCCCTCCTATCATTTTATCTCTTGCT
CTTTTTCTCACGACATCACA

Product: 3-demethylubiquinone-9 3-methyltransferase

Products: NA

Alternate protein names: 3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase; DHHB methyltransferase [H]

Number of amino acids: Translated: 241; Mature: 241

Protein sequence:

>241_residues
MKKELRTMTQQLNVDPAEIKKFEDMASRWWDFEGEFKPLHQINPLRLNYVLTNANGLFGKKVLDVGCGGGILAESMAKQG
ADVIGLDMGKEPLTVARLHALETGTILEYIQSTAEQHAEEYPETYDVITCMEMLEHVPDPLSVIRACAKMIKPGGHVFFS
TLNRNIKSYLFAIVGAEHVLKLVPKGTHDHDKFIRPSELLKMLDQTALQERGITGLHYNPLTDAYSLGTNVDVNYIVHTT
L

Sequences:

>Translated_241_residues
MKKELRTMTQQLNVDPAEIKKFEDMASRWWDFEGEFKPLHQINPLRLNYVLTNANGLFGKKVLDVGCGGGILAESMAKQG
ADVIGLDMGKEPLTVARLHALETGTILEYIQSTAEQHAEEYPETYDVITCMEMLEHVPDPLSVIRACAKMIKPGGHVFFS
TLNRNIKSYLFAIVGAEHVLKLVPKGTHDHDKFIRPSELLKMLDQTALQERGITGLHYNPLTDAYSLGTNVDVNYIVHTT
L
>Mature_241_residues
MKKELRTMTQQLNVDPAEIKKFEDMASRWWDFEGEFKPLHQINPLRLNYVLTNANGLFGKKVLDVGCGGGILAESMAKQG
ADVIGLDMGKEPLTVARLHALETGTILEYIQSTAEQHAEEYPETYDVITCMEMLEHVPDPLSVIRACAKMIKPGGHVFFS
TLNRNIKSYLFAIVGAEHVLKLVPKGTHDHDKFIRPSELLKMLDQTALQERGITGLHYNPLTDAYSLGTNVDVNYIVHTT
L

Specific function: Ubiquinone biosynthesis. [C]

COG id: COG2227

COG function: function code H; 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. UbiG/COQ3 family [H]

Homologues:

Organism=Homo sapiens, GI118600965, Length=243, Percent_Identity=35.3909465020576, Blast_Score=175, Evalue=4e-44,
Organism=Escherichia coli, GI1788564, Length=227, Percent_Identity=69.6035242290749, Blast_Score=347, Evalue=4e-97,
Organism=Caenorhabditis elegans, GI115533050, Length=234, Percent_Identity=32.0512820512821, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6324476, Length=246, Percent_Identity=32.1138211382114, Blast_Score=125, Evalue=9e-30,
Organism=Drosophila melanogaster, GI281365311, Length=236, Percent_Identity=33.0508474576271, Blast_Score=152, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24585589, Length=228, Percent_Identity=33.3333333333333, Blast_Score=148, Evalue=3e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR010233 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: =2.1.1.64 [H]

Molecular weight: Translated: 27009; Mature: 27009

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKELRTMTQQLNVDPAEIKKFEDMASRWWDFEGEFKPLHQINPLRLNYVLTNANGLFGK
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCEEEEEEEECCCCCHHH
KVLDVGCGGGILAESMAKQGADVIGLDMGKEPLTVARLHALETGTILEYIQSTAEQHAEE
HHHHCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YPETYDVITCMEMLEHVPDPLSVIRACAKMIKPGGHVFFSTLNRNIKSYLFAIVGAEHVL
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KLVPKGTHDHDKFIRPSELLKMLDQTALQERGITGLHYNPLTDAYSLGTNVDVNYIVHTT
HHCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCEEEEEEEC
L
C
>Mature Secondary Structure
MKKELRTMTQQLNVDPAEIKKFEDMASRWWDFEGEFKPLHQINPLRLNYVLTNANGLFGK
CCHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCHHHCCCCEEEEEEEECCCCCHHH
KVLDVGCGGGILAESMAKQGADVIGLDMGKEPLTVARLHALETGTILEYIQSTAEQHAEE
HHHHCCCCCHHHHHHHHHCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YPETYDVITCMEMLEHVPDPLSVIRACAKMIKPGGHVFFSTLNRNIKSYLFAIVGAEHVL
CCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
KLVPKGTHDHDKFIRPSELLKMLDQTALQERGITGLHYNPLTDAYSLGTNVDVNYIVHTT
HHCCCCCCCHHHCCCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCEEEEEEEC
L
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA