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The map label for this gene is aspC [H]

Identifier: 209695181

GI number: 209695181

Start: 1782903

End: 1784102

Strand: Direct

Name: aspC [H]

Synonym: VSAL_I1687

Alternate gene names: 209695181

Gene position: 1782903-1784102 (Clockwise)

Preceding gene: 209695180

Following gene: 209695184

Centisome position: 53.62

GC content: 40.83

Gene sequence:

>1200_bases
ATGATGACTATGTTTGAAAAAATCTCTGCCGCTCCAGCTGATCCAATTCTTGGCCTAACTGATGAATTTAAAAATGACCC
TCGTGCTGAAAAAATCAACTTAGGTGTTGGTATTTATAAGAACGAAGCGGGTCAGACTCCAGTATTGAAAACAGTAAAAA
AAGCAGAAGCTGTATTGCTTGATACTGAAAAAACAAAGTCATATTTAACCATCCAAGGTACTGCAGAATACGGCCTAGCC
GTTCAAAAACTGTTGTTTGGCAATAACGCTGATGTCATTACAGAAAAACGCACTCAAACAGCACAAGCGCCTGGTGGTAC
TGGTGCACTTCGTGTAGCTGGTGAATTCATTAAACGCCAATTAGGCAATGTGAAAATTTGGATCAGTAACCCAACATGGG
CAAACCACATTGGTGTATTTACTGCTGCTGGTATCGAAACTGCACAATACAGCTACTACAACGCAGAAACTAAATCGAAA
GATTTCGCTGCAATGATGGCAGATTTACAACAAGCAGAATCTGGTGATGTTGTATTACTGCACGGATGTTGTCACAACCC
AACAGGTATTGATCCAACAGATGCTGAATGGGAAGAACTAGCAAAATTATGTGCAAATAAAGGATTATTACCACTGTTTG
ATTTTGCGTACCAAGGTTTTGCTAAAGGCGTTGAAGAAGATGCTTCTGGTCTTCGTACTTTTGCTCAATACTGCCCAGAA
TTACTTGTTGCGAGTTCGTTCTCTAAAAACTTCGGTTTATACAATGAACGTGTCGGTGCATTTACGCTGGTAGCTAAAGA
CCCTGAAGTTTCTGTTACTGCGTTCTCACAAGTGAAAGCAATTATTCGCTCTATTTACTCTAACCCACCAGCTCATGGTG
CCGCTGTCGTTACTTACATCTTAAATGATGATGCGTTGCGTACTGAGTGGGAACAAGAAGTACAAGAAATGCGAGCTCGT
ATTCAAGAGATGCGTACTCTGTTTGTTACCACTCTAAAAGAGCAAGGCGTAGACGCTAATTTCAGCTTTATTGAACGTCA
AAATGGCATGTTCTCTTTCTCTGGTCTGTCTAAAGAACAAGTGAATCGCCTAAAAGATGAGTTTGCAATTTACATCGTTG
GTTCAGGTCGAATCAGTGTTGCTGGTATGACGAAAGACAACATGCTGCCATTATGTAAAGGCATTGCCGCTGTTCTTTAA

Upstream 100 bases:

>100_bases
AAAATCACTTTTTTCGTTATCTAATCGTTGCAAACTTACAAGGTAAACGGGTATAAATAACTAAACCGTTCTTAAACTTT
TTATTTTAATCTCACCATGG

Downstream 100 bases:

>100_bases
GTCTAGCCGATAAGTAAATATCAAAAAAGGCGCTAAATACGTTTGTGTAAACAAGGTATTCAGCGCCTTTTTTTATTATC
ATTCAACCAATAAAAATGAA

Product: aromatic amino acid aminotransferase

Products: NA

Alternate protein names: AspAT; Transaminase A [H]

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MMTMFEKISAAPADPILGLTDEFKNDPRAEKINLGVGIYKNEAGQTPVLKTVKKAEAVLLDTEKTKSYLTIQGTAEYGLA
VQKLLFGNNADVITEKRTQTAQAPGGTGALRVAGEFIKRQLGNVKIWISNPTWANHIGVFTAAGIETAQYSYYNAETKSK
DFAAMMADLQQAESGDVVLLHGCCHNPTGIDPTDAEWEELAKLCANKGLLPLFDFAYQGFAKGVEEDASGLRTFAQYCPE
LLVASSFSKNFGLYNERVGAFTLVAKDPEVSVTAFSQVKAIIRSIYSNPPAHGAAVVTYILNDDALRTEWEQEVQEMRAR
IQEMRTLFVTTLKEQGVDANFSFIERQNGMFSFSGLSKEQVNRLKDEFAIYIVGSGRISVAGMTKDNMLPLCKGIAAVL

Sequences:

>Translated_399_residues
MMTMFEKISAAPADPILGLTDEFKNDPRAEKINLGVGIYKNEAGQTPVLKTVKKAEAVLLDTEKTKSYLTIQGTAEYGLA
VQKLLFGNNADVITEKRTQTAQAPGGTGALRVAGEFIKRQLGNVKIWISNPTWANHIGVFTAAGIETAQYSYYNAETKSK
DFAAMMADLQQAESGDVVLLHGCCHNPTGIDPTDAEWEELAKLCANKGLLPLFDFAYQGFAKGVEEDASGLRTFAQYCPE
LLVASSFSKNFGLYNERVGAFTLVAKDPEVSVTAFSQVKAIIRSIYSNPPAHGAAVVTYILNDDALRTEWEQEVQEMRAR
IQEMRTLFVTTLKEQGVDANFSFIERQNGMFSFSGLSKEQVNRLKDEFAIYIVGSGRISVAGMTKDNMLPLCKGIAAVL
>Mature_399_residues
MMTMFEKISAAPADPILGLTDEFKNDPRAEKINLGVGIYKNEAGQTPVLKTVKKAEAVLLDTEKTKSYLTIQGTAEYGLA
VQKLLFGNNADVITEKRTQTAQAPGGTGALRVAGEFIKRQLGNVKIWISNPTWANHIGVFTAAGIETAQYSYYNAETKSK
DFAAMMADLQQAESGDVVLLHGCCHNPTGIDPTDAEWEELAKLCANKGLLPLFDFAYQGFAKGVEEDASGLRTFAQYCPE
LLVASSFSKNFGLYNERVGAFTLVAKDPEVSVTAFSQVKAIIRSIYSNPPAHGAAVVTYILNDDALRTEWEQEVQEMRAR
IQEMRTLFVTTLKEQGVDANFSFIERQNGMFSFSGLSKEQVNRLKDEFAIYIVGSGRISVAGMTKDNMLPLCKGIAAVL

Specific function: Unknown

COG id: COG1448

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI73486658, Length=396, Percent_Identity=42.6767676767677, Blast_Score=329, Evalue=4e-90,
Organism=Homo sapiens, GI4504067, Length=394, Percent_Identity=40.6091370558376, Blast_Score=306, Evalue=2e-83,
Organism=Homo sapiens, GI117414139, Length=383, Percent_Identity=26.8929503916449, Blast_Score=143, Evalue=2e-34,
Organism=Escherichia coli, GI1787159, Length=396, Percent_Identity=62.6262626262626, Blast_Score=531, Evalue=1e-152,
Organism=Escherichia coli, GI1790488, Length=397, Percent_Identity=42.8211586901763, Blast_Score=353, Evalue=8e-99,
Organism=Caenorhabditis elegans, GI71981858, Length=399, Percent_Identity=41.8546365914787, Blast_Score=350, Evalue=1e-96,
Organism=Caenorhabditis elegans, GI25147133, Length=397, Percent_Identity=40.3022670025189, Blast_Score=324, Evalue=4e-89,
Organism=Caenorhabditis elegans, GI17569539, Length=397, Percent_Identity=37.27959697733, Blast_Score=286, Evalue=1e-77,
Organism=Caenorhabditis elegans, GI17569537, Length=389, Percent_Identity=29.8200514138817, Blast_Score=191, Evalue=6e-49,
Organism=Caenorhabditis elegans, GI25147136, Length=213, Percent_Identity=38.0281690140845, Blast_Score=173, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17550384, Length=263, Percent_Identity=34.2205323193916, Blast_Score=168, Evalue=4e-42,
Organism=Saccharomyces cerevisiae, GI6323055, Length=407, Percent_Identity=37.3464373464373, Blast_Score=292, Evalue=6e-80,
Organism=Saccharomyces cerevisiae, GI6322743, Length=430, Percent_Identity=31.8604651162791, Blast_Score=231, Evalue=1e-61,
Organism=Drosophila melanogaster, GI24580970, Length=398, Percent_Identity=40.7035175879397, Blast_Score=326, Evalue=2e-89,
Organism=Drosophila melanogaster, GI24580972, Length=398, Percent_Identity=40.7035175879397, Blast_Score=325, Evalue=3e-89,
Organism=Drosophila melanogaster, GI19922362, Length=401, Percent_Identity=41.645885286783, Blast_Score=322, Evalue=2e-88,
Organism=Drosophila melanogaster, GI24654046, Length=401, Percent_Identity=41.645885286783, Blast_Score=322, Evalue=3e-88,
Organism=Drosophila melanogaster, GI19920542, Length=389, Percent_Identity=41.1311053984576, Blast_Score=321, Evalue=7e-88,

Paralogues:

None

Copy number: 6,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000796
- InterPro:   IPR004838
- InterPro:   IPR015424
- InterPro:   IPR015421 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.1 [H]

Molecular weight: Translated: 43662; Mature: 43662

Theoretical pI: Translated: 5.18; Mature: 5.18

Prosite motif: PS00105 AA_TRANSFER_CLASS_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTMFEKISAAPADPILGLTDEFKNDPRAEKINLGVGIYKNEAGQTPVLKTVKKAEAVLL
CCCHHHHHHCCCCCCCCCCCHHHCCCCCCEEEEECEEEEECCCCCCHHHHHHHHHHEEEE
DTEKTKSYLTIQGTAEYGLAVQKLLFGNNADVITEKRTQTAQAPGGTGALRVAGEFIKRQ
ECCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEECCCHHHCCCCCCCCHHHHHHHHHHHH
LGNVKIWISNPTWANHIGVFTAAGIETAQYSYYNAETKSKDFAAMMADLQQAESGDVVLL
HCCEEEEECCCCCCHHCCEEEECCCCHHHEEEECCCCCCHHHHHHHHHHHHCCCCCEEEE
HGCCHNPTGIDPTDAEWEELAKLCANKGLLPLFDFAYQGFAKGVEEDASGLRTFAQYCPE
ECCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LLVASSFSKNFGLYNERVGAFTLVAKDPEVSVTAFSQVKAIIRSIYSNPPAHGAAVVTYI
HHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
LNDDALRTEWEQEVQEMRARIQEMRTLFVTTLKEQGVDANFSFIERQNGMFSFSGLSKEQ
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEECCCCHHH
VNRLKDEFAIYIVGSGRISVAGMTKDNMLPLCKGIAAVL
HHHHHHCEEEEEEECCEEEEEECCCCCCHHHHHHHHHHC
>Mature Secondary Structure
MMTMFEKISAAPADPILGLTDEFKNDPRAEKINLGVGIYKNEAGQTPVLKTVKKAEAVLL
CCCHHHHHHCCCCCCCCCCCHHHCCCCCCEEEEECEEEEECCCCCCHHHHHHHHHHEEEE
DTEKTKSYLTIQGTAEYGLAVQKLLFGNNADVITEKRTQTAQAPGGTGALRVAGEFIKRQ
ECCCCCCEEEEECCHHHHHHHHHHHHCCCCCEEECCCHHHCCCCCCCCHHHHHHHHHHHH
LGNVKIWISNPTWANHIGVFTAAGIETAQYSYYNAETKSKDFAAMMADLQQAESGDVVLL
HCCEEEEECCCCCCHHCCEEEECCCCHHHEEEECCCCCCHHHHHHHHHHHHCCCCCEEEE
HGCCHNPTGIDPTDAEWEELAKLCANKGLLPLFDFAYQGFAKGVEEDASGLRTFAQYCPE
ECCCCCCCCCCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
LLVASSFSKNFGLYNERVGAFTLVAKDPEVSVTAFSQVKAIIRSIYSNPPAHGAAVVTYI
HHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCCCEEEEEE
LNDDALRTEWEQEVQEMRARIQEMRTLFVTTLKEQGVDANFSFIERQNGMFSFSGLSKEQ
ECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEECCCCHHH
VNRLKDEFAIYIVGSGRISVAGMTKDNMLPLCKGIAAVL
HHHHHHCEEEEEEECCEEEEEECCCCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6378205; 3897210; 3521591; 3298240; 8905232; 9278503; 9298646; 1868057; 2007566; 2513875; 1993208; 9891001 [H]