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The map label for this gene is sbcB [H]

Identifier: 209695175

GI number: 209695175

Start: 1775608

End: 1777032

Strand: Direct

Name: sbcB [H]

Synonym: VSAL_I1680

Alternate gene names: 209695175

Gene position: 1775608-1777032 (Clockwise)

Preceding gene: 209695174

Following gene: 209695176

Centisome position: 53.4

GC content: 41.82

Gene sequence:

>1425_bases
ATGCCGCAGGATAACGCACCAAGTTTCTTCTTCTTTGATTATGAAACATGGGGAACAAGTCCCTCTTTAGATCGCCCTTG
CCAATTTGCAGGTGTGCGAACCGATGAAGACTTTAATATTATTGGTGAGCCATTAGTCATTTATTGTCGCCCTCCTATCG
ATTACTTACCTTCTCCTGAAGCGTGTTTGATTACTGGCATTACTCCGCAAATGGCGGTCAGTAAAGGTCTGTCTGAGCCT
GAGTTTATTGCTCAAATCCATAACGAGCTATCAAAACCAAACACCTGTTCTTTAGGTTATAACAACATTCGTTTTGATGA
TGAAGTTTCTCGCTACACCTTATATCGCAACTTCTTCGAACCGTATGGTTGGAGCTGGCAAAATGGTAATTCACGCTGGG
ATTTACTTGATGTGATGCGTGCTGTTTATGCGCTACGTCCTGAAGGTATTGAATGGCCAAAAGACGAAGAAGGCAAGCCA
AGCTTTAGATTAGAAAAACTCTCTCAAGCAAACGGCATTGAGCATGAAAACGCCCATGATGCGATGGCCGATGTTATTGC
GACAATTGAGCTCGCTAAAGTTGTGAAAAAAGCACAGCCTAAAATGTTTAACTACCTACTTTCTATGCGCCATAAAAAGA
AAGCGGCGACATTAATCGACATTATTGAAATGACGCCATTGATGCACGTATCTGGTATGTTCGGCGTCGATAGAGGAAAC
ATCAGTTGGATTGTGCCTGTTGCTTGGCATCCAACCAACAACAATGCGGTGATCACGATTGATTTAGCGTTAGACCCTGC
GGTTTTTCTTGAGCTAGATGCAGAACAATTACACCAACGTATGTATACCAAGCGTTCTGAATTGGGTCCTGATGAATTAC
CGGTCCCTGTTAAGCTTGTTCATCTTAACAAATGCCCTATTCTTGCCCCAGCAAAAACGTTAACGGCTGAAAATGCTATC
GCGCTTAATGTTGATCGTGAAGCGTGTTTGCGAAACTTGAAAGTGATTCGTGAAAACCCAGAAATTCGCCAAAAGTTGAT
CGACTTATACAATATTGAACCTGGCTATGAGAAATCGTCAAATGTAGATACTTTACTTTATGATGGCTTTTTCTCTCATG
CAGATAAAACAGCCATTGATATGATCCGTCAATCAACGCCTGAACAGCTTATTGATTTTGAACCGAATGTGAGTGATCCT
CGTATCAAGCCATTATTGTTCCGCTATCGTGCTCGTAACTTCCCGCACACGTTAAATGAATCAGAACAACTACGTTGGCA
AGCGCATCTACAAGATTATTTTGAGACGCACATGTCTGATTACGAAACACGCTTTGAAAGCTTATACCTTGAGTCTGAAG
GTAATGAGAAAAAGACTGCGATTCTTCGCGCCGTTTATAATTACGTACAACAGTTAGTATCATGA

Upstream 100 bases:

>100_bases
AAGTCCTCTGTAAATTTTCATCTCGCTTATTCTTCTAATGCCTTGCGATTATGTGATAGATCTCTGATAATTAATGCATT
GCTATTAATTGGACACATTT

Downstream 100 bases:

>100_bases
TTAAATATATTTACTCTTTTGCTTGGATCTTTGGATCTTTGCTTCTTTGTTTGCAGGAAATGGCATTCAATCTTGGTTAT
CCATATCGGTACCTGGCAGC

Product: exonuclease I

Products: NA

Alternate protein names: Exonuclease I; DNA deoxyribophosphodiesterase; dRPase [H]

Number of amino acids: Translated: 474; Mature: 473

Protein sequence:

>474_residues
MPQDNAPSFFFFDYETWGTSPSLDRPCQFAGVRTDEDFNIIGEPLVIYCRPPIDYLPSPEACLITGITPQMAVSKGLSEP
EFIAQIHNELSKPNTCSLGYNNIRFDDEVSRYTLYRNFFEPYGWSWQNGNSRWDLLDVMRAVYALRPEGIEWPKDEEGKP
SFRLEKLSQANGIEHENAHDAMADVIATIELAKVVKKAQPKMFNYLLSMRHKKKAATLIDIIEMTPLMHVSGMFGVDRGN
ISWIVPVAWHPTNNNAVITIDLALDPAVFLELDAEQLHQRMYTKRSELGPDELPVPVKLVHLNKCPILAPAKTLTAENAI
ALNVDREACLRNLKVIRENPEIRQKLIDLYNIEPGYEKSSNVDTLLYDGFFSHADKTAIDMIRQSTPEQLIDFEPNVSDP
RIKPLLFRYRARNFPHTLNESEQLRWQAHLQDYFETHMSDYETRFESLYLESEGNEKKTAILRAVYNYVQQLVS

Sequences:

>Translated_474_residues
MPQDNAPSFFFFDYETWGTSPSLDRPCQFAGVRTDEDFNIIGEPLVIYCRPPIDYLPSPEACLITGITPQMAVSKGLSEP
EFIAQIHNELSKPNTCSLGYNNIRFDDEVSRYTLYRNFFEPYGWSWQNGNSRWDLLDVMRAVYALRPEGIEWPKDEEGKP
SFRLEKLSQANGIEHENAHDAMADVIATIELAKVVKKAQPKMFNYLLSMRHKKKAATLIDIIEMTPLMHVSGMFGVDRGN
ISWIVPVAWHPTNNNAVITIDLALDPAVFLELDAEQLHQRMYTKRSELGPDELPVPVKLVHLNKCPILAPAKTLTAENAI
ALNVDREACLRNLKVIRENPEIRQKLIDLYNIEPGYEKSSNVDTLLYDGFFSHADKTAIDMIRQSTPEQLIDFEPNVSDP
RIKPLLFRYRARNFPHTLNESEQLRWQAHLQDYFETHMSDYETRFESLYLESEGNEKKTAILRAVYNYVQQLVS
>Mature_473_residues
PQDNAPSFFFFDYETWGTSPSLDRPCQFAGVRTDEDFNIIGEPLVIYCRPPIDYLPSPEACLITGITPQMAVSKGLSEPE
FIAQIHNELSKPNTCSLGYNNIRFDDEVSRYTLYRNFFEPYGWSWQNGNSRWDLLDVMRAVYALRPEGIEWPKDEEGKPS
FRLEKLSQANGIEHENAHDAMADVIATIELAKVVKKAQPKMFNYLLSMRHKKKAATLIDIIEMTPLMHVSGMFGVDRGNI
SWIVPVAWHPTNNNAVITIDLALDPAVFLELDAEQLHQRMYTKRSELGPDELPVPVKLVHLNKCPILAPAKTLTAENAIA
LNVDREACLRNLKVIRENPEIRQKLIDLYNIEPGYEKSSNVDTLLYDGFFSHADKTAIDMIRQSTPEQLIDFEPNVSDPR
IKPLLFRYRARNFPHTLNESEQLRWQAHLQDYFETHMSDYETRFESLYLESEGNEKKTAILRAVYNYVQQLVS

Specific function: Also functions as a DNA deoxyribophosphodiesterase that releases deoxyribose-phosphate moieties following the cleavage DNA at an apurinic/apyrimidinic (AP) site by either an AP endonuclease AP lyase [H]

COG id: COG2925

COG function: function code L; Exonuclease I

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1788321, Length=467, Percent_Identity=54.389721627409, Blast_Score=544, Evalue=1e-156,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013620
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T; PF08411 Exonuc_X-T_C [H]

EC number: =3.1.11.1 [H]

Molecular weight: Translated: 54509; Mature: 54377

Theoretical pI: Translated: 5.00; Mature: 5.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPQDNAPSFFFFDYETWGTSPSLDRPCQFAGVRTDEDFNIIGEPLVIYCRPPIDYLPSPE
CCCCCCCCEEEEEECCCCCCCCCCCCCHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
ACLITGITPQMAVSKGLSEPEFIAQIHNELSKPNTCSLGYNNIRFDDEVSRYTLYRNFFE
CEEEECCCHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHC
PYGWSWQNGNSRWDLLDVMRAVYALRPEGIEWPKDEEGKPSFRLEKLSQANGIEHENAHD
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHH
AMADVIATIELAKVVKKAQPKMFNYLLSMRHKKKAATLIDIIEMTPLMHVSGMFGVDRGN
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCC
ISWIVPVAWHPTNNNAVITIDLALDPAVFLELDAEQLHQRMYTKRSELGPDELPVPVKLV
EEEEEEEEEECCCCCEEEEEEEEECCEEEEEECHHHHHHHHHHHHHCCCCCCCCCCEEEE
HLNKCPILAPAKTLTAENAIALNVDREACLRNLKVIRENPEIRQKLIDLYNIEPGYEKSS
EECCCCCCCCHHHHCCCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
NVDTLLYDGFFSHADKTAIDMIRQSTPEQLIDFEPNVSDPRIKPLLFRYRARNFPHTLNE
CCCEEEECCHHHHCCHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
SEQLRWQAHLQDYFETHMSDYETRFESLYLESEGNEKKTAILRAVYNYVQQLVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure 
PQDNAPSFFFFDYETWGTSPSLDRPCQFAGVRTDEDFNIIGEPLVIYCRPPIDYLPSPE
CCCCCCCEEEEEECCCCCCCCCCCCCHHCCCCCCCCCCCCCCCEEEEECCCCCCCCCCC
ACLITGITPQMAVSKGLSEPEFIAQIHNELSKPNTCSLGYNNIRFDDEVSRYTLYRNFFE
CEEEECCCHHHHHHCCCCCHHHHHHHHHHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHC
PYGWSWQNGNSRWDLLDVMRAVYALRPEGIEWPKDEEGKPSFRLEKLSQANGIEHENAHD
CCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCHHH
AMADVIATIELAKVVKKAQPKMFNYLLSMRHKKKAATLIDIIEMTPLMHVSGMFGVDRGN
HHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCC
ISWIVPVAWHPTNNNAVITIDLALDPAVFLELDAEQLHQRMYTKRSELGPDELPVPVKLV
EEEEEEEEEECCCCCEEEEEEEEECCEEEEEECHHHHHHHHHHHHHCCCCCCCCCCEEEE
HLNKCPILAPAKTLTAENAIALNVDREACLRNLKVIRENPEIRQKLIDLYNIEPGYEKSS
EECCCCCCCCHHHHCCCCEEEEECCHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCC
NVDTLLYDGFFSHADKTAIDMIRQSTPEQLIDFEPNVSDPRIKPLLFRYRARNFPHTLNE
CCCEEEECCHHHHCCHHHHHHHHHCCCHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCCC
SEQLRWQAHLQDYFETHMSDYETRFESLYLESEGNEKKTAILRAVYNYVQQLVS
HHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3539937; 9097040; 9278503; 1329027 [H]