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The map label for this gene is 209695033

Identifier: 209695033

GI number: 209695033

Start: 1630109

End: 1630489

Strand: Direct

Name: 209695033

Synonym: VSAL_I1528

Alternate gene names: NA

Gene position: 1630109-1630489 (Clockwise)

Preceding gene: 209695032

Following gene: 209695034

Centisome position: 49.02

GC content: 38.32

Gene sequence:

>381_bases
ATGAAGATCAGTCATTTAGACCATCTGGTGTTAACGGTTAAAGACATTACAGCAACCGTTGAGTTTTATTCTAAAATATT
AGGCATGGAAGCGGTGTATTTTGCAAAAGACAGAGTCGCTCTATCTTTTGGTCATCAGAAAATCAATTTACACCAGTCAG
GTAACGAATTTGAACCAAAAGCACAGTATGTGCAGAGTGGAAGTGCTGATTTATGTTTCATTACGGACACCCCTATCATT
GAGGTAAAAGCGCACATAGAACAACAAGGTGTTACTGTTTTTGAGGGACCAATACAGCGAACAGGGGCGATAGGCAATAT
CATCTCTGTTTATTTTAGAGATCTTGATGGTAACCTGATTGAAGTCTCCAATTATTTATAG

Upstream 100 bases:

>100_bases
CTCACTAAAGACGCTTCATTAATTGAACTTGCTCATGAAATGTTTTTAGATATCATCGATTCTAAGTAAGTTACCTTACA
TCATAATAGGGGCGGGTAGA

Downstream 100 bases:

>100_bases
TCTTCACTTCCAATAGCGTTATAACGATTAATACCGTCAATTCCTATTTATATGCAAACTGATTTTCAGCATGGTGAATT
TAAAATAGTTGACTTAATCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 126; Mature: 126

Protein sequence:

>126_residues
MKISHLDHLVLTVKDITATVEFYSKILGMEAVYFAKDRVALSFGHQKINLHQSGNEFEPKAQYVQSGSADLCFITDTPII
EVKAHIEQQGVTVFEGPIQRTGAIGNIISVYFRDLDGNLIEVSNYL

Sequences:

>Translated_126_residues
MKISHLDHLVLTVKDITATVEFYSKILGMEAVYFAKDRVALSFGHQKINLHQSGNEFEPKAQYVQSGSADLCFITDTPII
EVKAHIEQQGVTVFEGPIQRTGAIGNIISVYFRDLDGNLIEVSNYL
>Mature_126_residues
MKISHLDHLVLTVKDITATVEFYSKILGMEAVYFAKDRVALSFGHQKINLHQSGNEFEPKAQYVQSGSADLCFITDTPII
EVKAHIEQQGVTVFEGPIQRTGAIGNIISVYFRDLDGNLIEVSNYL

Specific function: Is critically involved in promoting the replication of S.typhimurium cells inside host macrophages, suggesting a role in the establishment of bacterial colonization within macrophages. May be involved in the biosynthesis and modification of the peptidogly

COG id: COG0346

COG function: function code E; Lactoylglutathione lyase and related lyases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI254039722, Length=124, Percent_Identity=57.258064516129, Blast_Score=151, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004360 [H]

Pfam domain/function: PF00903 Glyoxalase [H]

EC number: NA

Molecular weight: Translated: 14058; Mature: 14058

Theoretical pI: Translated: 5.52; Mature: 5.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKISHLDHLVLTVKDITATVEFYSKILGMEAVYFAKDRVALSFGHQKINLHQSGNEFEPK
CCCCCHHEEEEEHHHHHHHHHHHHHHHCCHHEEEECCEEEEEECCEEEEEECCCCCCCCH
AQYVQSGSADLCFITDTPIIEVKAHIEQQGVTVFEGPIQRTGAIGNIISVYFRDLDGNLI
HHHHHCCCCCEEEEECCCEEEEEEEHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCCCEE
EVSNYL
EEECCC
>Mature Secondary Structure
MKISHLDHLVLTVKDITATVEFYSKILGMEAVYFAKDRVALSFGHQKINLHQSGNEFEPK
CCCCCHHEEEEEHHHHHHHHHHHHHHHCCHHEEEECCEEEEEECCEEEEEECCCCCCCCH
AQYVQSGSADLCFITDTPIIEVKAHIEQQGVTVFEGPIQRTGAIGNIISVYFRDLDGNLI
HHHHHCCCCCEEEEECCCEEEEEEEHHHCCCEEEECCCCCCCCHHHHHHHHHHCCCCCEE
EVSNYL
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]