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The map label for this gene is atoS [H]

Identifier: 209694927

GI number: 209694927

Start: 1520143

End: 1522170

Strand: Direct

Name: atoS [H]

Synonym: VSAL_I1403

Alternate gene names: 209694927

Gene position: 1520143-1522170 (Clockwise)

Preceding gene: 209694922

Following gene: 209694928

Centisome position: 45.72

GC content: 39.15

Gene sequence:

>2028_bases
ATGATGTTATCGCCATCACTTTGGAAGCGTCGTATAAAAACCATGGTGCGCTATCGTCTATTGTGGCTTAACTCTGTGCC
TTTATTTTTGACAATGCTTGCTCTTATTATCATTACGGCATTTTGGTCAATTCATTACACATGGCAGAATGCCTTAAATG
ATGTAGGCAGTAAACTTTCTGTTGCGAATAACAGTATTGAACTTTTGCAGAGAGAACAAAGTGCAGAGTTAGGTGGTTTT
GTTGATTCTTATGCCTTTCAAATTAAATTGAAAAATGGGCAAGATTATATACAGCGCTGGTCAAGTAATCAGGCAGCTAA
ATATCATGCTGACTTTATTTCATTACATCCTGCCAATTACGCAAAAAAGTTACCTGAGACATTAGAAAGGCAAATGTACC
TTGGTCGATCTCGGACGTTTTTCCAAGTGATGGATGAGACCGCTTTAGTTGAAATTGATGAAGATCTGCCTAAGCGTGTC
AGTATTAGAAACAAAGATAACAACATTATTGAAACGAGAGGGCTGATCAGTCGAACACTGATCCCTATTTTCAATGAGCA
TGGCAGCTTAGAGTGGATAGTAGACAGTGGGATTATCCTGAATAACAGCACATCCTTGGTTGATAGAATTAGAGATCTTA
TTTATCCTGAAGGTAAGGGAGCCACAGAGCAAGTTGGTACGGTGACCTTATTTTTAGATGATTTGAGGATCAGTACGAAT
GTGTTTACGGATGATATATCAGGACAAGAACGCGCGATTGGTACTGAAGTCTCACCAGAGGTAAAACATCAAGTCATTGA
AAATGGTGAACGTTGGGTCAATAGAGCATACGTCTATAATGATTGGTATATTTCGGCATACAAACCCATTACTGATCTTA
ATGGGAATGTTGTTGGGATGTTGTATACCGGGTATCTAGAATGGCCATTATTAAAACAATACATCTATAACCTGTTGCAA
GCGGGCATCACGATTCTTATCACACTCTTATTATCGACTATTTTTGTTCATCGTGGGGCGAGAGATCTTTTCCAACCAAT
TGAAAGAATACACTATGTAGTAAAATCCGTTCAACTTGGAAAGAATGACCGAATAGGCGATCTTGGTCTTGATAATGGGC
ATGAATTGGCCAGTTTGGCGCAGCAATTTGATAATATGCTCGATCAATTGCAATTACGAAACAGCCAAATTCAACGAGCA
TCAAAAGAGCTTGAATCAAAGGTTGAATCAAGAACCGCCAGTTTGCATGAAAAAACCATTGAGCTTGAGCAATACATTAA
GCTATTAAAGCAAGCTCAAGATAAATTGATCATGAGTGAAAAACTGGCCTCATTAGGGGAGTTAACCGCGGGCATTGCCC
ATGAGATTAATAACCCAACGGCTGTGATATTAGGAAATGCAGAGCTGATCAAGTATGAGCTCGGTGATAATGCAAGCGTA
GTATCGGAAGAGTTAGATGCCATCATGGAACAAATTGATCGCATTCGTAATATTACTCGAAGTCTACTTCAATACAGCCG
TCAGGGAGGGATTCAAGATGAGGTTACTTGGCAATACATTAATCCTATTATTGAAGAAAGCGTCACTCTGGTACGAACTG
GTGCACATAAGCGGGATATTGACGTTGAGTTTGATTTCGAACAACCCCCAAGAGTTGAAGTAAACAGACATCACTTATTG
CAAGTATTAGTCAACTTACAGATGAACGGTATTCATGCAATGAAGGCAAAAGGTAAACTCATTATTCGAAGCAGAACGTG
GCAAGAAGAAGAGATAAACTTGGGGGCGATAATTGAAGTTGAAGATTTTGGTTCTGGTATGAGCCATGAACAATTAGGAC
GAATTTTCGATCCTTTTTATACGACTAAGCGTGATGGTACTGGGCTTGGATTATCTGTTTCTCAAAGTTTATTAAGCCAA
ACGGGAGGGGAGATTAAAGTACGATCTCAACTTGGTGAAGGGACTGTATTTACGATTTATCTACCAACCAAATCAGAACA
TTATCCATATGATAATTTGATCGGTTAA

Upstream 100 bases:

>100_bases
TGGATATGCATGAAGGGAATAAGTCAGCAGCGGCAAGACAACTCGGGGTTGCTCGTAAGACGTTAGAGCGTAAGTTTAAA
GAATGGAGTGAAGAGCGTGC

Downstream 100 bases:

>100_bases
CCATACTATGTTTAAAAGAGAGAATAATGAAAAAACCAATCCAACAAAAAATAGGCAGTGTTGCACTCGTTGTTGAAAAT
TACGATGATGCGATTGAATT

Product: signal transduction protein, histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 675; Mature: 675

Protein sequence:

>675_residues
MMLSPSLWKRRIKTMVRYRLLWLNSVPLFLTMLALIIITAFWSIHYTWQNALNDVGSKLSVANNSIELLQREQSAELGGF
VDSYAFQIKLKNGQDYIQRWSSNQAAKYHADFISLHPANYAKKLPETLERQMYLGRSRTFFQVMDETALVEIDEDLPKRV
SIRNKDNNIIETRGLISRTLIPIFNEHGSLEWIVDSGIILNNSTSLVDRIRDLIYPEGKGATEQVGTVTLFLDDLRISTN
VFTDDISGQERAIGTEVSPEVKHQVIENGERWVNRAYVYNDWYISAYKPITDLNGNVVGMLYTGYLEWPLLKQYIYNLLQ
AGITILITLLLSTIFVHRGARDLFQPIERIHYVVKSVQLGKNDRIGDLGLDNGHELASLAQQFDNMLDQLQLRNSQIQRA
SKELESKVESRTASLHEKTIELEQYIKLLKQAQDKLIMSEKLASLGELTAGIAHEINNPTAVILGNAELIKYELGDNASV
VSEELDAIMEQIDRIRNITRSLLQYSRQGGIQDEVTWQYINPIIEESVTLVRTGAHKRDIDVEFDFEQPPRVEVNRHHLL
QVLVNLQMNGIHAMKAKGKLIIRSRTWQEEEINLGAIIEVEDFGSGMSHEQLGRIFDPFYTTKRDGTGLGLSVSQSLLSQ
TGGEIKVRSQLGEGTVFTIYLPTKSEHYPYDNLIG

Sequences:

>Translated_675_residues
MMLSPSLWKRRIKTMVRYRLLWLNSVPLFLTMLALIIITAFWSIHYTWQNALNDVGSKLSVANNSIELLQREQSAELGGF
VDSYAFQIKLKNGQDYIQRWSSNQAAKYHADFISLHPANYAKKLPETLERQMYLGRSRTFFQVMDETALVEIDEDLPKRV
SIRNKDNNIIETRGLISRTLIPIFNEHGSLEWIVDSGIILNNSTSLVDRIRDLIYPEGKGATEQVGTVTLFLDDLRISTN
VFTDDISGQERAIGTEVSPEVKHQVIENGERWVNRAYVYNDWYISAYKPITDLNGNVVGMLYTGYLEWPLLKQYIYNLLQ
AGITILITLLLSTIFVHRGARDLFQPIERIHYVVKSVQLGKNDRIGDLGLDNGHELASLAQQFDNMLDQLQLRNSQIQRA
SKELESKVESRTASLHEKTIELEQYIKLLKQAQDKLIMSEKLASLGELTAGIAHEINNPTAVILGNAELIKYELGDNASV
VSEELDAIMEQIDRIRNITRSLLQYSRQGGIQDEVTWQYINPIIEESVTLVRTGAHKRDIDVEFDFEQPPRVEVNRHHLL
QVLVNLQMNGIHAMKAKGKLIIRSRTWQEEEINLGAIIEVEDFGSGMSHEQLGRIFDPFYTTKRDGTGLGLSVSQSLLSQ
TGGEIKVRSQLGEGTVFTIYLPTKSEHYPYDNLIG
>Mature_675_residues
MMLSPSLWKRRIKTMVRYRLLWLNSVPLFLTMLALIIITAFWSIHYTWQNALNDVGSKLSVANNSIELLQREQSAELGGF
VDSYAFQIKLKNGQDYIQRWSSNQAAKYHADFISLHPANYAKKLPETLERQMYLGRSRTFFQVMDETALVEIDEDLPKRV
SIRNKDNNIIETRGLISRTLIPIFNEHGSLEWIVDSGIILNNSTSLVDRIRDLIYPEGKGATEQVGTVTLFLDDLRISTN
VFTDDISGQERAIGTEVSPEVKHQVIENGERWVNRAYVYNDWYISAYKPITDLNGNVVGMLYTGYLEWPLLKQYIYNLLQ
AGITILITLLLSTIFVHRGARDLFQPIERIHYVVKSVQLGKNDRIGDLGLDNGHELASLAQQFDNMLDQLQLRNSQIQRA
SKELESKVESRTASLHEKTIELEQYIKLLKQAQDKLIMSEKLASLGELTAGIAHEINNPTAVILGNAELIKYELGDNASV
VSEELDAIMEQIDRIRNITRSLLQYSRQGGIQDEVTWQYINPIIEESVTLVRTGAHKRDIDVEFDFEQPPRVEVNRHHLL
QVLVNLQMNGIHAMKAKGKLIIRSRTWQEEEINLGAIIEVEDFGSGMSHEQLGRIFDPFYTTKRDGTGLGLSVSQSLLSQ
TGGEIKVRSQLGEGTVFTIYLPTKSEHYPYDNLIG

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=241, Percent_Identity=36.9294605809129, Blast_Score=152, Evalue=8e-38,
Organism=Escherichia coli, GI1790436, Length=243, Percent_Identity=34.9794238683128, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI87081816, Length=283, Percent_Identity=30.3886925795053, Blast_Score=97, Evalue=5e-21,
Organism=Escherichia coli, GI1790300, Length=244, Percent_Identity=32.3770491803279, Blast_Score=96, Evalue=7e-21,
Organism=Escherichia coli, GI1789149, Length=446, Percent_Identity=21.9730941704036, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786600, Length=245, Percent_Identity=22.4489795918367, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI145693157, Length=262, Percent_Identity=24.4274809160305, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1786912, Length=261, Percent_Identity=22.2222222222222, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 76911; Mature: 76911

Theoretical pI: Translated: 5.77; Mature: 5.77

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMLSPSLWKRRIKTMVRYRLLWLNSVPLFLTMLALIIITAFWSIHYTWQNALNDVGSKLS
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VANNSIELLQREQSAELGGFVDSYAFQIKLKNGQDYIQRWSSNQAAKYHADFISLHPANY
CCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHCCCCCCEEECHHEEECCHHH
AKKLPETLERQMYLGRSRTFFQVMDETALVEIDEDLPKRVSIRNKDNNIIETRGLISRTL
HHHHHHHHHHHHHHCCCCHHHHHHCCHHEEEECCCCCCCEEECCCCCCEEHHHHHHHHHH
IPIFNEHGSLEWIVDSGIILNNSTSLVDRIRDLIYPEGKGATEQVGTVTLFLDDLRISTN
HHHHCCCCCEEEEEECCEEECCCHHHHHHHHHHHCCCCCCCCHHHCEEEEEEECCEEECC
VFTDDISGQERAIGTEVSPEVKHQVIENGERWVNRAYVYNDWYISAYKPITDLNGNVVGM
EEECCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHEEEEEECEEEEEECCCCCCCCCEEEE
LYTGYLEWPLLKQYIYNLLQAGITILITLLLSTIFVHRGARDLFQPIERIHYVVKSVQLG
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
KNDRIGDLGLDNGHELASLAQQFDNMLDQLQLRNSQIQRASKELESKVESRTASLHEKTI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELEQYIKLLKQAQDKLIMSEKLASLGELTAGIAHEINNPTAVILGNAELIKYELGDNASV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEECCCCHHH
VSEELDAIMEQIDRIRNITRSLLQYSRQGGIQDEVTWQYINPIIEESVTLVRTGAHKRDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHEECCCCCCCC
DVEFDFEQPPRVEVNRHHLLQVLVNLQMNGIHAMKAKGKLIIRSRTWQEEEINLGAIIEV
CEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCHHCCCCEEEEEE
EDFGSGMSHEQLGRIFDPFYTTKRDGTGLGLSVSQSLLSQTGGEIKVRSQLGEGTVFTIY
CCCCCCCCHHHHHHHHCHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEEE
LPTKSEHYPYDNLIG
ECCCCCCCCCCCCCC
>Mature Secondary Structure
MMLSPSLWKRRIKTMVRYRLLWLNSVPLFLTMLALIIITAFWSIHYTWQNALNDVGSKLS
CCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEE
VANNSIELLQREQSAELGGFVDSYAFQIKLKNGQDYIQRWSSNQAAKYHADFISLHPANY
CCCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCHHHHHHHCCCCCCEEECHHEEECCHHH
AKKLPETLERQMYLGRSRTFFQVMDETALVEIDEDLPKRVSIRNKDNNIIETRGLISRTL
HHHHHHHHHHHHHHCCCCHHHHHHCCHHEEEECCCCCCCEEECCCCCCEEHHHHHHHHHH
IPIFNEHGSLEWIVDSGIILNNSTSLVDRIRDLIYPEGKGATEQVGTVTLFLDDLRISTN
HHHHCCCCCEEEEEECCEEECCCHHHHHHHHHHHCCCCCCCCHHHCEEEEEEECCEEECC
VFTDDISGQERAIGTEVSPEVKHQVIENGERWVNRAYVYNDWYISAYKPITDLNGNVVGM
EEECCCCCCCCCCCCCCCHHHHHHHHHCHHHHHHEEEEEECEEEEEECCCCCCCCCEEEE
LYTGYLEWPLLKQYIYNLLQAGITILITLLLSTIFVHRGARDLFQPIERIHYVVKSVQLG
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCC
KNDRIGDLGLDNGHELASLAQQFDNMLDQLQLRNSQIQRASKELESKVESRTASLHEKTI
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ELEQYIKLLKQAQDKLIMSEKLASLGELTAGIAHEINNPTAVILGNAELIKYELGDNASV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEECCCCHHH
VSEELDAIMEQIDRIRNITRSLLQYSRQGGIQDEVTWQYINPIIEESVTLVRTGAHKRDI
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCHHHEECCCCCCCC
DVEFDFEQPPRVEVNRHHLLQVLVNLQMNGIHAMKAKGKLIIRSRTWQEEEINLGAIIEV
CEEECCCCCCCCCCCHHHHHHHHHHHHCCCEEEEECCCEEEEEECCCCHHCCCCEEEEEE
EDFGSGMSHEQLGRIFDPFYTTKRDGTGLGLSVSQSLLSQTGGEIKVRSQLGEGTVFTIY
CCCCCCCCHHHHHHHHCHHHCCCCCCCCCCHHHHHHHHHCCCCCEEEEEECCCCCEEEEE
LPTKSEHYPYDNLIG
ECCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]